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The map label for this gene is PotE6 [H]

Identifier: 20808968

GI number: 20808968

Start: 2515112

End: 2516539

Strand: Direct

Name: PotE6 [H]

Synonym: TTE2623

Alternate gene names: 20808968

Gene position: 2515112-2516539 (Clockwise)

Preceding gene: 20808967

Following gene: 20808982

Centisome position: 93.52

GC content: 41.18

Gene sequence:

>1428_bases
ATGGCAAATTCAACGTCTTCTTATTTGTGGCGTAAAAAGACGCTTGAGATGGTGCTTTCTGAAACCGAAGCTGAACAATT
CAAATTAAAGAAAACATTAACAGCTATTGACTTAATTGCATTAGGTATAGGCGCAATCATAGGTACTGGTATATTTGTTA
TTACTGGTGTTGCCGCCGCTGAAAAAGCTGGTCCCGCAATCGTGCTCTCATTTATTTTGGCAGGATTGGCTTGTGCTTTC
GCAGCAATTTCTTACGCAGAACTTGCATCCATGTTCCCCATAGCAGGTTCTACGTATAACTACGCATATATAGCAATGGG
TGAATTTTTGGCCTGGATAATTGGATGGGACTTAATACTTGAGTACGTATTTGCTCTTCCTGCAATTTCATTGGGTTGGT
CTGGTTATTTCACCAACCTCCTTGGAAGTATAGGAATAAACATTCCTGCATGGGCAGCTAACTCTGCATGGCAAGCACCC
GGTACTGGCGGTCTTATCAATCTTCCAGCAATAGGAATCCTTCTTGCCATCGCAATTTTAAACTACATCGGGGTAAGAGA
AACTGCTACTGTTAACAACATTGGTGTTGCTTTCAAGGTATTTGTGGTACTTTTCTTCATATTCACAGCAGTTTGGTATG
TAAAGCCAGCTAACTGGTCTCCTTTCTTGCCATACGGATGGGCAGGCGTATTCCACGGCGCAGCAATCATCTTCTTTGCA
TATATAGGATTTGACGCTGTTTCAACAGCAGCTGAAGAGACAAAGAATCCAGCAAAAGATATGCCCATAGGAATTTTAGG
ATCTCTTGGAATTAGTACCCTTTTGTACATCGCTGTTTCAGCGATTTTGACAGGTGTTGTTTCATACACCGAGTTGAACG
ACCCAGCCCCTGTTGCAAAGGCTCTCAACTTAATAGGTCTAAACTGGGCAAGAGGACTTGTTTCACTAGGTGCCATTGTA
GGTATTACAACAGTTTTGCTTGTTATGTTCTACGGCTCCACAAGAATTATCTTTGCTATGTCTCGTGATGGATTACTCCC
ACCTATTTTCTCAAAAGTTCATCCAAAATATAGAACACCTACTCTCGCTATATATCTCATAACGATTGCAACAACTTTAG
TAGCTGGATTTTTCCCAATTGGCGTAATCGCAGAACTTGTAAATATAGGAACTATGTTGGCATTTGTATTAACTTCTATC
GCTACAATAGTATTAAGATACACACAACCTGACTTGCCGAGAAAATTCAGAGCTCCTGGCATGCCATGGACTGGTATTTT
GGCAATAGCTTTTGTACTTTCACTTATGGTATCTCTGCCATGGGAGACATGGGTAAGACTTATTGTATGGTTCGTAATAG
GGCTCTTCATCTACTTTGGATATGGTAGACACAACAGCATACTTGCTAAACAGCAGACCCAGCATTAA

Upstream 100 bases:

>100_bases
AATGTGGTATTTTTGAAAGAGGGGGGGATGTGTTGGATTTGGGATATGTTAAAATTTTGTAAGTATACAAACAATTTTTT
AAAAAGGGGGTTACATCTTA

Downstream 100 bases:

>100_bases
AGAAATAAAAAGGCGGCGATTTTGCCGCCTTTTTATTTCTGCTTTCTATATTTCAATTAATTCGCTTTCAATATTTCTTA
AAGCCATCCCTATTTTAGAT

Product: amino acid transporters

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MANSTSSYLWRKKTLEMVLSETEAEQFKLKKTLTAIDLIALGIGAIIGTGIFVITGVAAAEKAGPAIVLSFILAGLACAF
AAISYAELASMFPIAGSTYNYAYIAMGEFLAWIIGWDLILEYVFALPAISLGWSGYFTNLLGSIGINIPAWAANSAWQAP
GTGGLINLPAIGILLAIAILNYIGVRETATVNNIGVAFKVFVVLFFIFTAVWYVKPANWSPFLPYGWAGVFHGAAIIFFA
YIGFDAVSTAAEETKNPAKDMPIGILGSLGISTLLYIAVSAILTGVVSYTELNDPAPVAKALNLIGLNWARGLVSLGAIV
GITTVLLVMFYGSTRIIFAMSRDGLLPPIFSKVHPKYRTPTLAIYLITIATTLVAGFFPIGVIAELVNIGTMLAFVLTSI
ATIVLRYTQPDLPRKFRAPGMPWTGILAIAFVLSLMVSLPWETWVRLIVWFVIGLFIYFGYGRHNSILAKQQTQH

Sequences:

>Translated_475_residues
MANSTSSYLWRKKTLEMVLSETEAEQFKLKKTLTAIDLIALGIGAIIGTGIFVITGVAAAEKAGPAIVLSFILAGLACAF
AAISYAELASMFPIAGSTYNYAYIAMGEFLAWIIGWDLILEYVFALPAISLGWSGYFTNLLGSIGINIPAWAANSAWQAP
GTGGLINLPAIGILLAIAILNYIGVRETATVNNIGVAFKVFVVLFFIFTAVWYVKPANWSPFLPYGWAGVFHGAAIIFFA
YIGFDAVSTAAEETKNPAKDMPIGILGSLGISTLLYIAVSAILTGVVSYTELNDPAPVAKALNLIGLNWARGLVSLGAIV
GITTVLLVMFYGSTRIIFAMSRDGLLPPIFSKVHPKYRTPTLAIYLITIATTLVAGFFPIGVIAELVNIGTMLAFVLTSI
ATIVLRYTQPDLPRKFRAPGMPWTGILAIAFVLSLMVSLPWETWVRLIVWFVIGLFIYFGYGRHNSILAKQQTQH
>Mature_474_residues
ANSTSSYLWRKKTLEMVLSETEAEQFKLKKTLTAIDLIALGIGAIIGTGIFVITGVAAAEKAGPAIVLSFILAGLACAFA
AISYAELASMFPIAGSTYNYAYIAMGEFLAWIIGWDLILEYVFALPAISLGWSGYFTNLLGSIGINIPAWAANSAWQAPG
TGGLINLPAIGILLAIAILNYIGVRETATVNNIGVAFKVFVVLFFIFTAVWYVKPANWSPFLPYGWAGVFHGAAIIFFAY
IGFDAVSTAAEETKNPAKDMPIGILGSLGISTLLYIAVSAILTGVVSYTELNDPAPVAKALNLIGLNWARGLVSLGAIVG
ITTVLLVMFYGSTRIIFAMSRDGLLPPIFSKVHPKYRTPTLAIYLITIATTLVAGFFPIGVIAELVNIGTMLAFVLTSIA
TIVLRYTQPDLPRKFRAPGMPWTGILAIAFVLSLMVSLPWETWVRLIVWFVIGLFIYFGYGRHNSILAKQQTQH

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=431, Percent_Identity=32.4825986078886, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI114326550, Length=431, Percent_Identity=32.4825986078886, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4507047, Length=434, Percent_Identity=33.1797235023041, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI181337167, Length=415, Percent_Identity=34.6987951807229, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI258614005, Length=420, Percent_Identity=33.8095238095238, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI258614003, Length=420, Percent_Identity=33.8095238095238, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=34.2857142857143, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI110347453, Length=405, Percent_Identity=34.320987654321, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI187423910, Length=490, Percent_Identity=24.0816326530612, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI7657591, Length=490, Percent_Identity=24.0816326530612, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI33286428, Length=408, Percent_Identity=24.7549019607843, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI71979932, Length=230, Percent_Identity=29.1304347826087, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87082023, Length=460, Percent_Identity=25.8695652173913, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081869, Length=389, Percent_Identity=25.706940874036, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788480, Length=387, Percent_Identity=28.9405684754522, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786694, Length=423, Percent_Identity=23.8770685579196, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082250, Length=354, Percent_Identity=26.271186440678, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786302, Length=448, Percent_Identity=23.6607142857143, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789017, Length=444, Percent_Identity=24.5495495495495, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790653, Length=494, Percent_Identity=22.8744939271255, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786602, Length=477, Percent_Identity=23.2704402515723, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786789, Length=456, Percent_Identity=21.7105263157895, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=391, Percent_Identity=36.8286445012788, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17533459, Length=419, Percent_Identity=34.1288782816229, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=33.8164251207729, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17537453, Length=393, Percent_Identity=24.9363867684478, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17568033, Length=425, Percent_Identity=24, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=418, Percent_Identity=25.5980861244019, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71990446, Length=379, Percent_Identity=24.802110817942, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993915, Length=392, Percent_Identity=23.469387755102, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321629, Length=391, Percent_Identity=24.8081841432225, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667468, Length=398, Percent_Identity=37.6884422110553, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI221512776, Length=459, Percent_Identity=34.640522875817, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24666159, Length=459, Percent_Identity=34.640522875817, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24668806, Length=430, Percent_Identity=32.7906976744186, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI21356285, Length=430, Percent_Identity=32.7906976744186, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24668802, Length=430, Percent_Identity=32.7906976744186, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI161077963, Length=421, Percent_Identity=34.4418052256532, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI281366235, Length=416, Percent_Identity=32.9326923076923, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI116007820, Length=416, Percent_Identity=32.9326923076923, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=32.3671497584541, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=32.3671497584541, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21357367, Length=423, Percent_Identity=22.9314420803783, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221331183, Length=418, Percent_Identity=25.1196172248804, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17647653, Length=418, Percent_Identity=25.1196172248804, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24664379, Length=418, Percent_Identity=25.1196172248804, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651635, Length=438, Percent_Identity=24.6575342465753, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24651633, Length=438, Percent_Identity=24.6575342465753, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641993, Length=425, Percent_Identity=25.1764705882353, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641995, Length=425, Percent_Identity=25.4117647058824, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51190; Mature: 51059

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSTSSYLWRKKTLEMVLSETEAEQFKLKKTLTAIDLIALGIGAIIGTGIFVITGVAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAGPAIVLSFILAGLACAFAAISYAELASMFPIAGSTYNYAYIAMGEFLAWIIGWDLIL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYVFALPAISLGWSGYFTNLLGSIGINIPAWAANSAWQAPGTGGLINLPAIGILLAIAIL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
NYIGVRETATVNNIGVAFKVFVVLFFIFTAVWYVKPANWSPFLPYGWAGVFHGAAIIFFA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
YIGFDAVSTAAEETKNPAKDMPIGILGSLGISTLLYIAVSAILTGVVSYTELNDPAPVAK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALNLIGLNWARGLVSLGAIVGITTVLLVMFYGSTRIIFAMSRDGLLPPIFSKVHPKYRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCCCC
TLAIYLITIATTLVAGFFPIGVIAELVNIGTMLAFVLTSIATIVLRYTQPDLPRKFRAPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
MPWTGILAIAFVLSLMVSLPWETWVRLIVWFVIGLFIYFGYGRHNSILAKQQTQH
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
ANSTSSYLWRKKTLEMVLSETEAEQFKLKKTLTAIDLIALGIGAIIGTGIFVITGVAAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAGPAIVLSFILAGLACAFAAISYAELASMFPIAGSTYNYAYIAMGEFLAWIIGWDLIL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EYVFALPAISLGWSGYFTNLLGSIGINIPAWAANSAWQAPGTGGLINLPAIGILLAIAIL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
NYIGVRETATVNNIGVAFKVFVVLFFIFTAVWYVKPANWSPFLPYGWAGVFHGAAIIFFA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
YIGFDAVSTAAEETKNPAKDMPIGILGSLGISTLLYIAVSAILTGVVSYTELNDPAPVAK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALNLIGLNWARGLVSLGAIVGITTVLLVMFYGSTRIIFAMSRDGLLPPIFSKVHPKYRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCCCC
TLAIYLITIATTLVAGFFPIGVIAELVNIGTMLAFVLTSIATIVLRYTQPDLPRKFRAPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
MPWTGILAIAFVLSLMVSLPWETWVRLIVWFVIGLFIYFGYGRHNSILAKQQTQH
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]