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The map label for this gene is 20808959

Identifier: 20808959

GI number: 20808959

Start: 2500702

End: 2501787

Strand: Reverse

Name: 20808959

Synonym: TTE2614

Alternate gene names: NA

Gene position: 2501787-2500702 (Counterclockwise)

Preceding gene: 20808960

Following gene: 20808958

Centisome position: 93.02

GC content: 37.38

Gene sequence:

>1086_bases
ATGGAAGATATGCTACTTATGACGCCGGGGCCGACAATGGTACCAGAAGAAGTGAAAAAAGTTGCAGGTATGCAGCCTTT
TCATCACAGGACAGAAGAATTTTATCAATTATTCTCCAAGCTCAATGAAAATTTAAAGAAAATATTTCAGACAAAAAATG
AAGTTATAACTCTTACCTCTTCAGGAACAGGTGGAATGGAAGCCGCTGTAGCTAATCTTTTCTCTGCGGGAGATAAAGTC
TTAGTTGCAAGTATAGGATATTTTGGAGAGAGATTTTATGATATAGCTAGGGCTTATGGGCTTGATGCGGAAATTTATGA
CTTTGGGTGGGGAAATGCAGTAGATTTAGATATATTAGAAGATAAACTTAAAAAAGGGAATTATAAAGCCCTTTTAGTTA
CTCATAATGAAACCTCAACAGGAGTGACAAATAATATAGAAAATATAGCAAAAATCGCAAATAGGTACAATGTTCCCGTG
ATAGTAGATGCGGTAAGTTCATTGGGGGGAATACCGCTTAAAATGGATGAATGGGGGATTGACGCCGTCATTACTTGCTC
CCAGAAGTGCTTAATGTCGCCCCCAGGTTTAAGCTTCATCGCCTTAAGTGATAGAGCATGGGAAATGACTAAAACATCCA
ATCTACCAAAATACTATTTTGACCTTAGAAAAGCGAGAGAAGGAGTATTAAAGCCTAAGCCTGATACGCCTGCTACTCCT
GCTGTATCCACAATAATGGCTGTAGCAAAGGCGACAGATATGCTTTTAGAAAAAGGATTAGATAATGTATACAAAAAACA
ATCCGAGTACGGCAAAAAAGTGAGAAAATATGTAAAGGAATTAGGTTTAGACCTACTTCCTAGTGAAGAGGTAGCTTCTA
ATTTAATTACTGCTATAAAAGTTCCAGAAAGGTACAAAGCATCAGATATAATAAACTATATGAAGGAAAAGCACAGAGTT
TTAATCACAGGAGGACAGGGGCCTTTAAAAGGCAAGATTATTAGAATTGGCCACATGGGTTATCTGACAGATGAAATGTT
AGATAAAGCATTATATGCCCTAAAAGATGCCATATCCTCACTGTGA

Upstream 100 bases:

>100_bases
ATAATGTCCTTACTTCACGGACACATGTATTTTTCACTTGCATTTTTCACTTCATTGATTTATCATATTAAATATACACC
AAGTGACGGGGAGTGGGAAA

Downstream 100 bases:

>100_bases
ATTGAAGAAATGGGAGGGAAAGGATTTTGAAGATAATTGTCACAGAAAAAATCTCAGAAAATGGTATCGATTATCTTAAA
AAATACGCTGATGTTGACGT

Product: Serine-pyruvate aminotransferase/ aspartate aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MEDMLLMTPGPTMVPEEVKKVAGMQPFHHRTEEFYQLFSKLNENLKKIFQTKNEVITLTSSGTGGMEAAVANLFSAGDKV
LVASIGYFGERFYDIARAYGLDAEIYDFGWGNAVDLDILEDKLKKGNYKALLVTHNETSTGVTNNIENIAKIANRYNVPV
IVDAVSSLGGIPLKMDEWGIDAVITCSQKCLMSPPGLSFIALSDRAWEMTKTSNLPKYYFDLRKAREGVLKPKPDTPATP
AVSTIMAVAKATDMLLEKGLDNVYKKQSEYGKKVRKYVKELGLDLLPSEEVASNLITAIKVPERYKASDIINYMKEKHRV
LITGGQGPLKGKIIRIGHMGYLTDEMLDKALYALKDAISSL

Sequences:

>Translated_361_residues
MEDMLLMTPGPTMVPEEVKKVAGMQPFHHRTEEFYQLFSKLNENLKKIFQTKNEVITLTSSGTGGMEAAVANLFSAGDKV
LVASIGYFGERFYDIARAYGLDAEIYDFGWGNAVDLDILEDKLKKGNYKALLVTHNETSTGVTNNIENIAKIANRYNVPV
IVDAVSSLGGIPLKMDEWGIDAVITCSQKCLMSPPGLSFIALSDRAWEMTKTSNLPKYYFDLRKAREGVLKPKPDTPATP
AVSTIMAVAKATDMLLEKGLDNVYKKQSEYGKKVRKYVKELGLDLLPSEEVASNLITAIKVPERYKASDIINYMKEKHRV
LITGGQGPLKGKIIRIGHMGYLTDEMLDKALYALKDAISSL
>Mature_361_residues
MEDMLLMTPGPTMVPEEVKKVAGMQPFHHRTEEFYQLFSKLNENLKKIFQTKNEVITLTSSGTGGMEAAVANLFSAGDKV
LVASIGYFGERFYDIARAYGLDAEIYDFGWGNAVDLDILEDKLKKGNYKALLVTHNETSTGVTNNIENIAKIANRYNVPV
IVDAVSSLGGIPLKMDEWGIDAVITCSQKCLMSPPGLSFIALSDRAWEMTKTSNLPKYYFDLRKAREGVLKPKPDTPATP
AVSTIMAVAKATDMLLEKGLDNVYKKQSEYGKKVRKYVKELGLDLLPSEEVASNLITAIKVPERYKASDIINYMKEKHRV
LITGGQGPLKGKIIRIGHMGYLTDEMLDKALYALKDAISSL

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=368, Percent_Identity=30.1630434782609, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17536281, Length=355, Percent_Identity=29.8591549295775, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321079, Length=358, Percent_Identity=31.0055865921788, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17530823, Length=363, Percent_Identity=32.2314049586777, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 40005; Mature: 40005

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDMLLMTPGPTMVPEEVKKVAGMQPFHHRTEEFYQLFSKLNENLKKIFQTKNEVITLTS
CCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SGTGGMEAAVANLFSAGDKVLVASIGYFGERFYDIARAYGLDAEIYDFGWGNAVDLDILE
CCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHH
DKLKKGNYKALLVTHNETSTGVTNNIENIAKIANRYNVPVIVDAVSSLGGIPLKMDEWGI
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHEEHHHHHCCCCEEECCCCC
DAVITCSQKCLMSPPGLSFIALSDRAWEMTKTSNLPKYYFDLRKAREGVLKPKPDTPATP
CCEEECCHHHHCCCCCCEEEEECCCCEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
AVSTIMAVAKATDMLLEKGLDNVYKKQSEYGKKVRKYVKELGLDLLPSEEVASNLITAIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
VPERYKASDIINYMKEKHRVLITGGQGPLKGKIIRIGHMGYLTDEMLDKALYALKDAISS
CCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MEDMLLMTPGPTMVPEEVKKVAGMQPFHHRTEEFYQLFSKLNENLKKIFQTKNEVITLTS
CCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SGTGGMEAAVANLFSAGDKVLVASIGYFGERFYDIARAYGLDAEIYDFGWGNAVDLDILE
CCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHH
DKLKKGNYKALLVTHNETSTGVTNNIENIAKIANRYNVPVIVDAVSSLGGIPLKMDEWGI
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHEEHHHHHCCCCEEECCCCC
DAVITCSQKCLMSPPGLSFIALSDRAWEMTKTSNLPKYYFDLRKAREGVLKPKPDTPATP
CCEEECCHHHHCCCCCCEEEEECCCCEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
AVSTIMAVAKATDMLLEKGLDNVYKKQSEYGKKVRKYVKELGLDLLPSEEVASNLITAIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
VPERYKASDIINYMKEKHRVLITGGQGPLKGKIIRIGHMGYLTDEMLDKALYALKDAISS
CCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]