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The map label for this gene is His2.2 [H]

Identifier: 20808955

GI number: 20808955

Start: 2497617

End: 2498435

Strand: Direct

Name: His2.2 [H]

Synonym: TTE2610

Alternate gene names: 20808955

Gene position: 2497617-2498435 (Clockwise)

Preceding gene: 20808950

Following gene: 20808967

Centisome position: 92.87

GC content: 34.92

Gene sequence:

>819_bases
ATGCCAGCAGATTACCATGTACATATAGAAAATGGCCCATTTACTATTGAGTGGCTCAAAGAATTTGTAAATCAAGGGTT
AAAAAGAGGTTTAAAAGAAATAGGTATCTCTGAACACGGTCACAGGTTTAAAGAAGGTTTTGAGGCTTACAAAAGCGATG
GATTCAGAACAGAGTGGATAAAAACTTACATGGACCAAAGTATTGAAGATTACGTGGAACTTATCAAAGAAGCAAAACAA
ATGGGTCTTCCAGTTAAGCTGGGAATTGAAGCCGATTATTTTCCGGGAAAGGAAAAAGAAATAAGGGATTTCCTAACTCT
TTACCTGTGGGACTTTATAATAGGCTCTGTTCACTGGATTGACGATTGGGGAATAGACCTTGAAGAATCAATAGAGGAAT
GGCACAGAAGAAATGTTGATGAAGTATACCTGGAGTATTTTAATATAATTGAAAAAATGGCCAAGACAGGACTTTTTGAC
ATAATAGGGCACATTGACCTCGTGAAAATTTTTGGATTTAGACCCAATTATAAAGTTTTTGAAAAGATAGAAAGAAATAT
TGAAGAAATTTCTAAGACTGGCATAGTGATTGAGGTTTCAACTGCGGGATTGAGAAAACCTGTTGGAGAAATTTATCCTT
CAAAAGAGATAATGGCGATGATTAAGAAATACAATATCCCTGTTGTAGTAAATTCCGATGCTCACTACCCTGAACATGTG
GGATATGAATTTGAAAAAGCCTATAACTATGTAAAAGAATTCGGTATAAAGAGGCTTTATTATTTTGAGGGGAGAAAAAG
GATACCTTACAATATTTAA

Upstream 100 bases:

>100_bases
AAGTAAAGAGGAGATCGATTTATTTTATTATACCACAAATTGATTTCCTTTTTTCAAAATATTATAATGGCACTAAAGAT
GTGAGAAAGGATGTGGTTTT

Downstream 100 bases:

>100_bases
AGGAGCAAGAGTAACCTTGCTCCTTTATTATTTGTACACATCCCCTCTTGAATCGAAATCTTTTACTTTAATTACAAAAT
TTTCATTATCAACTTCGAAA

Product: PHP family histidinol phosphatase/hydrolase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPADYHVHIENGPFTIEWLKEFVNQGLKRGLKEIGISEHGHRFKEGFEAYKSDGFRTEWIKTYMDQSIEDYVELIKEAKQ
MGLPVKLGIEADYFPGKEKEIRDFLTLYLWDFIIGSVHWIDDWGIDLEESIEEWHRRNVDEVYLEYFNIIEKMAKTGLFD
IIGHIDLVKIFGFRPNYKVFEKIERNIEEISKTGIVIEVSTAGLRKPVGEIYPSKEIMAMIKKYNIPVVVNSDAHYPEHV
GYEFEKAYNYVKEFGIKRLYYFEGRKRIPYNI

Sequences:

>Translated_272_residues
MPADYHVHIENGPFTIEWLKEFVNQGLKRGLKEIGISEHGHRFKEGFEAYKSDGFRTEWIKTYMDQSIEDYVELIKEAKQ
MGLPVKLGIEADYFPGKEKEIRDFLTLYLWDFIIGSVHWIDDWGIDLEESIEEWHRRNVDEVYLEYFNIIEKMAKTGLFD
IIGHIDLVKIFGFRPNYKVFEKIERNIEEISKTGIVIEVSTAGLRKPVGEIYPSKEIMAMIKKYNIPVVVNSDAHYPEHV
GYEFEKAYNYVKEFGIKRLYYFEGRKRIPYNI
>Mature_271_residues
PADYHVHIENGPFTIEWLKEFVNQGLKRGLKEIGISEHGHRFKEGFEAYKSDGFRTEWIKTYMDQSIEDYVELIKEAKQM
GLPVKLGIEADYFPGKEKEIRDFLTLYLWDFIIGSVHWIDDWGIDLEESIEEWHRRNVDEVYLEYFNIIEKMAKTGLFDI
IGHIDLVKIFGFRPNYKVFEKIERNIEEISKTGIVIEVSTAGLRKPVGEIYPSKEIMAMIKKYNIPVVVNSDAHYPEHVG
YEFEKAYNYVKEFGIKRLYYFEGRKRIPYNI

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 32229; Mature: 32098

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADYHVHIENGPFTIEWLKEFVNQGLKRGLKEIGISEHGHRFKEGFEAYKSDGFRTEWI
CCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHH
KTYMDQSIEDYVELIKEAKQMGLPVKLGIEADYFPGKEKEIRDFLTLYLWDFIIGSVHWI
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEE
DDWGIDLEESIEEWHRRNVDEVYLEYFNIIEKMAKTGLFDIIGHIDLVKIFGFRPNYKVF
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EKIERNIEEISKTGIVIEVSTAGLRKPVGEIYPSKEIMAMIKKYNIPVVVNSDAHYPEHV
HHHHHHHHHHHHCCCEEEECCCHHHCCHHHHCCCHHHHHHHHHCCCCEEECCCCCCCHHH
GYEFEKAYNYVKEFGIKRLYYFEGRKRIPYNI
CCHHHHHHHHHHHHCCHHEEEECCCCCCCCCC
>Mature Secondary Structure 
PADYHVHIENGPFTIEWLKEFVNQGLKRGLKEIGISEHGHRFKEGFEAYKSDGFRTEWI
CCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHH
KTYMDQSIEDYVELIKEAKQMGLPVKLGIEADYFPGKEKEIRDFLTLYLWDFIIGSVHWI
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEE
DDWGIDLEESIEEWHRRNVDEVYLEYFNIIEKMAKTGLFDIIGHIDLVKIFGFRPNYKVF
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EKIERNIEEISKTGIVIEVSTAGLRKPVGEIYPSKEIMAMIKKYNIPVVVNSDAHYPEHV
HHHHHHHHHHHHCCCEEEECCCHHHCCHHHHCCCHHHHHHHHHCCCCEEECCCCCCCHHH
GYEFEKAYNYVKEFGIKRLYYFEGRKRIPYNI
CCHHHHHHHHHHHHCCHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]