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The map label for this gene is Apt2 [H]

Identifier: 20808923

GI number: 20808923

Start: 2463863

End: 2464687

Strand: Reverse

Name: Apt2 [H]

Synonym: TTE2574

Alternate gene names: 20808923

Gene position: 2464687-2463863 (Counterclockwise)

Preceding gene: 20808925

Following gene: 20808922

Centisome position: 91.64

GC content: 39.64

Gene sequence:

>825_bases
TTGATGGAAAAGTATAAAAGGTATGAGAGGCTTGTGGCTCTTCTCAAATTTTTTACTGACAATCCCAACAAATTGGTAAA
CCTCGAGCAGTTTATGGATATGTTTAATATAGCTAAGTCTTCGGCTTCAGAAGATATAGATATTTTAGAAGAGATATTAG
AAAAATTTGATATGGGGAAATTGATGACTTTTCCGGGGGCTGGCGGAGGAGTCAAGTATATCCCTGTTTCAAGTTTAAAA
AGCTATGTGCCTTTTGTGAAAGAGGTATGTGAAAGACTTAAAGACCCTTCAAGGATAATTCCAGGGGGTTTTCTGTACAC
AGCTGATTTGATTTATTCTCCTCCCATTGTGAGTAAAATTGCTGAGGTTTTAGTGTATCCCTTTATTGAAAAAGAGATTG
ACGCTGTTGTTACTGTGGAGACAAAAGGGATACCTATTGCCCTCATGTGCGCAAGGGTTTTGAATGTGCCACTGGTGATA
GTGAGGAAAGACAGCCGTGTGACAGAAGGTTCTTTTGTGTCCATAAATTATGTGTCAGGTTCTCAAAGGCATATAAGGTC
TATGTCGTTGGCAAGAAGGGCTCTTGACAAGGGAGCAAAAGTCCTCCTGGTGGACGATTTTATGAAGGCAGGAGGCACTT
TGAAGGGCATGACAGAGCTTATGGAAGAATTTGATGCTCATGTTGTGGGGGCAGGAGTGATGATTGCGACAGAGGAACCT
AGGGAGAAGTTGATAGACAATTACATCTCTATTTTTGTGTTAAAAAATGTGGAGGAAGAAAAGAATATTGTAGAGATAGA
GATAAGTGACTGGATCTTAAAATAA

Upstream 100 bases:

>100_bases
TGTTGTCACTGTTTTATAAAAAAATTATACCACATGTTGCAGAAAAGTGAACTTTTAAATATAATTTTAGTATAAAAGTT
TGTGAATTGGAGGTTAATTT

Downstream 100 bases:

>100_bases
AAATTTTTATTTCATGAAGGAAATTTTAAGTTTTTGGCGAATATATTAAAGAGAGGGATAAGCCTGATTCTTGCGGAGAT
TGCAAGAAAAAGACAGCAGT

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MMEKYKRYERLVALLKFFTDNPNKLVNLEQFMDMFNIAKSSASEDIDILEEILEKFDMGKLMTFPGAGGGVKYIPVSSLK
SYVPFVKEVCERLKDPSRIIPGGFLYTADLIYSPPIVSKIAEVLVYPFIEKEIDAVVTVETKGIPIALMCARVLNVPLVI
VRKDSRVTEGSFVSINYVSGSQRHIRSMSLARRALDKGAKVLLVDDFMKAGGTLKGMTELMEEFDAHVVGAGVMIATEEP
REKLIDNYISIFVLKNVEEEKNIVEIEISDWILK

Sequences:

>Translated_274_residues
MMEKYKRYERLVALLKFFTDNPNKLVNLEQFMDMFNIAKSSASEDIDILEEILEKFDMGKLMTFPGAGGGVKYIPVSSLK
SYVPFVKEVCERLKDPSRIIPGGFLYTADLIYSPPIVSKIAEVLVYPFIEKEIDAVVTVETKGIPIALMCARVLNVPLVI
VRKDSRVTEGSFVSINYVSGSQRHIRSMSLARRALDKGAKVLLVDDFMKAGGTLKGMTELMEEFDAHVVGAGVMIATEEP
REKLIDNYISIFVLKNVEEEKNIVEIEISDWILK
>Mature_274_residues
MMEKYKRYERLVALLKFFTDNPNKLVNLEQFMDMFNIAKSSASEDIDILEEILEKFDMGKLMTFPGAGGGVKYIPVSSLK
SYVPFVKEVCERLKDPSRIIPGGFLYTADLIYSPPIVSKIAEVLVYPFIEKEIDAVVTVETKGIPIALMCARVLNVPLVI
VRKDSRVTEGSFVSINYVSGSQRHIRSMSLARRALDKGAKVLLVDDFMKAGGTLKGMTELMEEFDAHVVGAGVMIATEEP
REKLIDNYISIFVLKNVEEEKNIVEIEISDWILK

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- ProDom:   PD029816 [H]

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N [H]

EC number: NA

Molecular weight: Translated: 30828; Mature: 30828

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKYKRYERLVALLKFFTDNPNKLVNLEQFMDMFNIAKSSASEDIDILEEILEKFDMGK
CCHHHHHHHHHHHHHHHHCCCCHHEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
LMTFPGAGGGVKYIPVSSLKSYVPFVKEVCERLKDPSRIIPGGFLYTADLIYSPPIVSKI
EEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHCCCHHHHHH
AEVLVYPFIEKEIDAVVTVETKGIPIALMCARVLNVPLVIVRKDSRVTEGSFVSINYVSG
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC
SQRHIRSMSLARRALDKGAKVLLVDDFMKAGGTLKGMTELMEEFDAHVVGAGVMIATEEP
CHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEECCCEEEECCCH
REKLIDNYISIFVLKNVEEEKNIVEIEISDWILK
HHHHHHHHHHHHHEECCCCCCCEEEEEECCHHCC
>Mature Secondary Structure
MMEKYKRYERLVALLKFFTDNPNKLVNLEQFMDMFNIAKSSASEDIDILEEILEKFDMGK
CCHHHHHHHHHHHHHHHHCCCCHHEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
LMTFPGAGGGVKYIPVSSLKSYVPFVKEVCERLKDPSRIIPGGFLYTADLIYSPPIVSKI
EEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHCCCHHHHHH
AEVLVYPFIEKEIDAVVTVETKGIPIALMCARVLNVPLVIVRKDSRVTEGSFVSINYVSG
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC
SQRHIRSMSLARRALDKGAKVLLVDDFMKAGGTLKGMTELMEEFDAHVVGAGVMIATEEP
CHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEECCCEEEECCCH
REKLIDNYISIFVLKNVEEEKNIVEIEISDWILK
HHHHHHHHHHHHHEECCCCCCCEEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7638212 [H]