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The map label for this gene is GntR [H]

Identifier: 20808907

GI number: 20808907

Start: 2446401

End: 2447078

Strand: Reverse

Name: GntR [H]

Synonym: TTE2558

Alternate gene names: 20808907

Gene position: 2447078-2446401 (Counterclockwise)

Preceding gene: 20808908

Following gene: 20808906

Centisome position: 90.99

GC content: 41.89

Gene sequence:

>678_bases
ATGAGCGAGTTTTTTACTCTGGAAAATTACAAGCCGCTACGGGATCTGGTTTTTGACTACATGAAAGAAGCTATAATAAC
AGGGAAGCTAAAGCCAGGAGAAAGGCTTATGGAAGTCCAGCTGGCAGAAAAGCTTGGGGTGAGCCGCACTCCTGTTAGAG
AGGCTATAAGAAAGCTGGAGCTTGAAGGACTTGTTGTAATGGTGCCTCGAAAGGGAGCGTATGTGGCGGATTTGAATGCG
AAAGACCTGTTGAACGTGTTGGAGGTCAGAAGTTCTTTAGAGGGATTGGCGGCTTCTCTTGCTGCAGAGAGGATTACTGA
TGAGGAAGTAGAGAAGCTCAAAAAGATCGTAGAGGAGTTTAGAATTAAAATGGAAGAGGGAGATTTAGAAGCGTTAATAA
GGCTTGATAAAGAGTTTCACGATTTAATTTTTGCCGCATCCCGTAATGACAAATTAATACAGATAATGAATAATTTACAA
GAGCATGTCCACCGGTTCAGGGTAAAATACATCACTGAGGAAAAGAAGGCAAAGAGAATCTATCAGGAACACAAAAAAAT
AGCTGAGCTAATTGAACAAAGAGATGCAAACGGGGCGAGAAAATGGGCAGAAAAGCACGTTCACAATTTTCAGGAAGAAG
TAGTAAGGGATTCAAAGTACTTCAGCGATAAGGAGTGA

Upstream 100 bases:

>100_bases
TTAATGATGTTGAAAAGCTTGTAAGGGCTTATCATGACCTTAAGGGAGTTTATCCTTTTGTTGCCATTTCTAAAACTATA
GACAAGGGGTTAGAAATATT

Downstream 100 bases:

>100_bases
GGCTGATGAACGCTGTTATTTTGGCCGGCAGTACCAAGGAGGACAAACTGCCTGATAAGGCATTTGTGAACCTTAAGGGG
AGATACATGATTTCTTATGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSEFFTLENYKPLRDLVFDYMKEAIITGKLKPGERLMEVQLAEKLGVSRTPVREAIRKLELEGLVVMVPRKGAYVADLNA
KDLLNVLEVRSSLEGLAASLAAERITDEEVEKLKKIVEEFRIKMEEGDLEALIRLDKEFHDLIFAASRNDKLIQIMNNLQ
EHVHRFRVKYITEEKKAKRIYQEHKKIAELIEQRDANGARKWAEKHVHNFQEEVVRDSKYFSDKE

Sequences:

>Translated_225_residues
MSEFFTLENYKPLRDLVFDYMKEAIITGKLKPGERLMEVQLAEKLGVSRTPVREAIRKLELEGLVVMVPRKGAYVADLNA
KDLLNVLEVRSSLEGLAASLAAERITDEEVEKLKKIVEEFRIKMEEGDLEALIRLDKEFHDLIFAASRNDKLIQIMNNLQ
EHVHRFRVKYITEEKKAKRIYQEHKKIAELIEQRDANGARKWAEKHVHNFQEEVVRDSKYFSDKE
>Mature_224_residues
SEFFTLENYKPLRDLVFDYMKEAIITGKLKPGERLMEVQLAEKLGVSRTPVREAIRKLELEGLVVMVPRKGAYVADLNAK
DLLNVLEVRSSLEGLAASLAAERITDEEVEKLKKIVEEFRIKMEEGDLEALIRLDKEFHDLIFAASRNDKLIQIMNNLQE
HVHRFRVKYITEEKKAKRIYQEHKKIAELIEQRDANGARKWAEKHVHNFQEEVVRDSKYFSDKE

Specific function: Unknown

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787821, Length=222, Percent_Identity=25.2252252252252, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87081914, Length=139, Percent_Identity=31.6546762589928, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=225, Percent_Identity=26.2222222222222, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789353, Length=220, Percent_Identity=27.7272727272727, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082149, Length=200, Percent_Identity=26, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI48994961, Length=201, Percent_Identity=28.3582089552239, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI48994955, Length=208, Percent_Identity=26.4423076923077, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000485
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26340; Mature: 26209

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFFTLENYKPLRDLVFDYMKEAIITGKLKPGERLMEVQLAEKLGVSRTPVREAIRKLE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LEGLVVMVPRKGAYVADLNAKDLLNVLEVRSSLEGLAASLAAERITDEEVEKLKKIVEEF
HCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RIKMEEGDLEALIRLDKEFHDLIFAASRNDKLIQIMNNLQEHVHRFRVKYITEEKKAKRI
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQEHKKIAELIEQRDANGARKWAEKHVHNFQEEVVRDSKYFSDKE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEFFTLENYKPLRDLVFDYMKEAIITGKLKPGERLMEVQLAEKLGVSRTPVREAIRKLE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LEGLVVMVPRKGAYVADLNAKDLLNVLEVRSSLEGLAASLAAERITDEEVEKLKKIVEEF
HCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RIKMEEGDLEALIRLDKEFHDLIFAASRNDKLIQIMNNLQEHVHRFRVKYITEEKKAKRI
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQEHKKIAELIEQRDANGARKWAEKHVHNFQEEVVRDSKYFSDKE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]