Click here to switch to the map view.

The map label for this gene is argS

Identifier: 20808887

GI number: 20808887

Start: 2424752

End: 2426440

Strand: Reverse

Name: argS

Synonym: TTE2533

Alternate gene names: 20808887

Gene position: 2426440-2424752 (Counterclockwise)

Preceding gene: 20808888

Following gene: 20808886

Centisome position: 90.22

GC content: 41.03

Gene sequence:

>1689_bases
TTGGAGAATATTGTTCAAAAAGCTAAAGAAGAGATAAAAGATGTTGTTTTAAAAGCATTAAATGAAGCTAAAAAAGAGGG
ATTGCTCAATTTTGAATCCATTCAAGATGTGGAAGTGGAAGAGCCAAAGGAAAAACAGCATGGGGACCTTGCTACCAATT
TTGCAATGGTTATGGCAAGAGAGGCAAAGATGGCTCCTCGTAAAATTGCAGAGATTATAGCTTCAAAAATGAATACTTCT
GGTACCTTTATAGAGAAGGTTGAAGTTGCTGGGCCAGGCTTTATCAACTTCTTTTTAAACCAAAATTTTTTGATTGAGAC
GCTTAAATTGATTCACAAAAGAGGAAAAGATTATGGAAGGGTTAACCTTGGAAAAGGCAAGAAGGTGCAGGTGGAATTTG
TTTCTGCTAACCCTACAGGTCCGATGCACATGGGAAATGCTAGAGGGGGAGCGATAGGAGACGTTTTGGCTTCCATACTC
GATTACGCGGGGTACAACGTTTCAAGGGAATTTTACATAAACGACGCGGGGAATCAGATAGAGAAGTTTGGATATTCCCT
TGAGGCTAGGTATTTGCAACTTCTTGGAATAGATGCAGAGGTGCCAGAAGGGGGTTACCACGGAGAGGACATAATAGACA
GAGCGAAAGAATTTTTAGAGATACACGGAGACAAGTATAAGGATGTGCCTTCTGAAGAGAGGAGAAAGGCTTTAATAGAA
TATGGGCTTAAAAAGAATATAGAGAAGATGAAAGAGGATTTGGTGCTTTACGGAATAGAGTATGACGTGTGGTTTTCTGA
GCAGTCCCTTTATGACAGCGGAGAAGTGTATAAAGTGATAGAGGAGCTTACAGAAAAGGGCTATACCTATGAAAAAGATG
GAGCATTGTGGTTTAAAATGACCCTTTTTGGCGCTGAGAAAGATGACGTTTTAGTGAGGTCAAATGGAGTTCCAACATAT
CTTGCCTCTGACATAGCTTATCACAAAAACAAGTTTGTGACGCGCGGATTTGACTGGGTGATAAATGTTTGGGGAGCTGA
CCACCATGGGCATGTCGCTCCTATGAAAGGGGCTATGAAGGCTTTGGGGATAGACCCCAACAGGCTGGATGTAGTTTTGA
TGCAGCTTGTCAAGCTTATAGAGGGCGGACAGGTAGTCAGGATGTCTAAAAGGACAGGAAAGATGATCACTTTAAGGGAT
TTGATAGAGGAAGTAGGTAAAGACGCAGCGAGATTTTTCTTCAATATGAGGTCTCCTGACAGCCCAATAGAGTTTGATTT
GGATTTAGCTAAGCAGCAGACGAATGAAAATCCCGTCTTTTACGTGCAGTACGCTCATGCGAGAATCTGTTCTATAATAA
GGCAGTTAGAGGAGATGGGGGTTAAGATAGAAAATATAGAAGATGTAGACCTTGGGCTTTTAAAAGAAGAGGAAGAGGTG
GATTTGATTAAAAAACTTGCCTATTTTCCTGAAGAAATAACTATAGCTGCGAAGACCTTGGCTCCTCACAGGATTACAAG
GTATGTCATAGACGTTGCTTCTCTTTTCCACTCTTTCTACAACAGCCATAGGGTGAAAGGAGCAGAGGAGAATTTAATGA
AAGCACGCTTTGCTCTGATTTTAGCTGTAAAGACTGTTCTAAAGAACGCTCTTGACATACTTAAAGTCACTGCTCCTGAA
AGAATGTAA

Upstream 100 bases:

>100_bases
GAGAGTGGAGGAGAGGTAAACATAAAGTATGTTCTCGACCTCAACAATAGAAAGGTAAGCAACAATGAACTATATCTAAA
AGTGCGGGAGGTAAATTGAG

Downstream 100 bases:

>100_bases
AGAAGGCGGTTTTTGCTGCCTTTTTTGTGTTATAATAGGTTTTAGGAGGTGGTCTTTTATGAAAATAAAATGGTTAGGAC
ACGCTTGCTTTAAATTGACT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MENIVQKAKEEIKDVVLKALNEAKKEGLLNFESIQDVEVEEPKEKQHGDLATNFAMVMAREAKMAPRKIAEIIASKMNTS
GTFIEKVEVAGPGFINFFLNQNFLIETLKLIHKRGKDYGRVNLGKGKKVQVEFVSANPTGPMHMGNARGGAIGDVLASIL
DYAGYNVSREFYINDAGNQIEKFGYSLEARYLQLLGIDAEVPEGGYHGEDIIDRAKEFLEIHGDKYKDVPSEERRKALIE
YGLKKNIEKMKEDLVLYGIEYDVWFSEQSLYDSGEVYKVIEELTEKGYTYEKDGALWFKMTLFGAEKDDVLVRSNGVPTY
LASDIAYHKNKFVTRGFDWVINVWGADHHGHVAPMKGAMKALGIDPNRLDVVLMQLVKLIEGGQVVRMSKRTGKMITLRD
LIEEVGKDAARFFFNMRSPDSPIEFDLDLAKQQTNENPVFYVQYAHARICSIIRQLEEMGVKIENIEDVDLGLLKEEEEV
DLIKKLAYFPEEITIAAKTLAPHRITRYVIDVASLFHSFYNSHRVKGAEENLMKARFALILAVKTVLKNALDILKVTAPE
RM

Sequences:

>Translated_562_residues
MENIVQKAKEEIKDVVLKALNEAKKEGLLNFESIQDVEVEEPKEKQHGDLATNFAMVMAREAKMAPRKIAEIIASKMNTS
GTFIEKVEVAGPGFINFFLNQNFLIETLKLIHKRGKDYGRVNLGKGKKVQVEFVSANPTGPMHMGNARGGAIGDVLASIL
DYAGYNVSREFYINDAGNQIEKFGYSLEARYLQLLGIDAEVPEGGYHGEDIIDRAKEFLEIHGDKYKDVPSEERRKALIE
YGLKKNIEKMKEDLVLYGIEYDVWFSEQSLYDSGEVYKVIEELTEKGYTYEKDGALWFKMTLFGAEKDDVLVRSNGVPTY
LASDIAYHKNKFVTRGFDWVINVWGADHHGHVAPMKGAMKALGIDPNRLDVVLMQLVKLIEGGQVVRMSKRTGKMITLRD
LIEEVGKDAARFFFNMRSPDSPIEFDLDLAKQQTNENPVFYVQYAHARICSIIRQLEEMGVKIENIEDVDLGLLKEEEEV
DLIKKLAYFPEEITIAAKTLAPHRITRYVIDVASLFHSFYNSHRVKGAEENLMKARFALILAVKTVLKNALDILKVTAPE
RM
>Mature_562_residues
MENIVQKAKEEIKDVVLKALNEAKKEGLLNFESIQDVEVEEPKEKQHGDLATNFAMVMAREAKMAPRKIAEIIASKMNTS
GTFIEKVEVAGPGFINFFLNQNFLIETLKLIHKRGKDYGRVNLGKGKKVQVEFVSANPTGPMHMGNARGGAIGDVLASIL
DYAGYNVSREFYINDAGNQIEKFGYSLEARYLQLLGIDAEVPEGGYHGEDIIDRAKEFLEIHGDKYKDVPSEERRKALIE
YGLKKNIEKMKEDLVLYGIEYDVWFSEQSLYDSGEVYKVIEELTEKGYTYEKDGALWFKMTLFGAEKDDVLVRSNGVPTY
LASDIAYHKNKFVTRGFDWVINVWGADHHGHVAPMKGAMKALGIDPNRLDVVLMQLVKLIEGGQVVRMSKRTGKMITLRD
LIEEVGKDAARFFFNMRSPDSPIEFDLDLAKQQTNENPVFYVQYAHARICSIIRQLEEMGVKIENIEDVDLGLLKEEEEV
DLIKKLAYFPEEITIAAKTLAPHRITRYVIDVASLFHSFYNSHRVKGAEENLMKARFALILAVKTVLKNALDILKVTAPE
RM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=575, Percent_Identity=24.8695652173913, Blast_Score=123, Evalue=5e-28,
Organism=Escherichia coli, GI1788184, Length=588, Percent_Identity=25.5102040816327, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71985061, Length=583, Percent_Identity=24.5283018867925, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=542, Percent_Identity=24.9077490774908, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=545, Percent_Identity=28.4403669724771, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321883, Length=555, Percent_Identity=24.6846846846847, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI18859963, Length=560, Percent_Identity=24.4642857142857, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_THETN (Q8R786)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624058.1
- ProteinModelPortal:   Q8R786
- GeneID:   996251
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2533
- NMPDR:   fig|273068.3.peg.2012
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   TTEN273068:TTE2533-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63694; Mature: 63694

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIVQKAKEEIKDVVLKALNEAKKEGLLNFESIQDVEVEEPKEKQHGDLATNFAMVMAR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHCCCHHHHHHHHHHH
EAKMAPRKIAEIIASKMNTSGTFIEKVEVAGPGFINFFLNQNFLIETLKLIHKRGKDYGR
HHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCE
VNLGKGKKVQVEFVSANPTGPMHMGNARGGAIGDVLASILDYAGYNVSREFYINDAGNQI
EECCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
EKFGYSLEARYLQLLGIDAEVPEGGYHGEDIIDRAKEFLEIHGDKYKDVPSEERRKALIE
HHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
YGLKKNIEKMKEDLVLYGIEYDVWFSEQSLYDSGEVYKVIEELTEKGYTYEKDGALWFKM
HHHHHHHHHHHHCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEE
TLFGAEKDDVLVRSNGVPTYLASDIAYHKNKFVTRGFDWVINVWGADHHGHVAPMKGAMK
EEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCHHHHHH
ALGIDPNRLDVVLMQLVKLIEGGQVVRMSKRTGKMITLRDLIEEVGKDAARFFFNMRSPD
HHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCHHHHHHEECCCCC
SPIEFDLDLAKQQTNENPVFYVQYAHARICSIIRQLEEMGVKIENIEDVDLGLLKEEEEV
CCCEECHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHH
DLIKKLAYFPEEITIAAKTLAPHRITRYVIDVASLFHSFYNSHRVKGAEENLMKARFALI
HHHHHHHHCCCHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAVKTVLKNALDILKVTAPERM
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MENIVQKAKEEIKDVVLKALNEAKKEGLLNFESIQDVEVEEPKEKQHGDLATNFAMVMAR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHCCCHHHHHHHHHHH
EAKMAPRKIAEIIASKMNTSGTFIEKVEVAGPGFINFFLNQNFLIETLKLIHKRGKDYGR
HHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCE
VNLGKGKKVQVEFVSANPTGPMHMGNARGGAIGDVLASILDYAGYNVSREFYINDAGNQI
EECCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
EKFGYSLEARYLQLLGIDAEVPEGGYHGEDIIDRAKEFLEIHGDKYKDVPSEERRKALIE
HHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
YGLKKNIEKMKEDLVLYGIEYDVWFSEQSLYDSGEVYKVIEELTEKGYTYEKDGALWFKM
HHHHHHHHHHHHCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEE
TLFGAEKDDVLVRSNGVPTYLASDIAYHKNKFVTRGFDWVINVWGADHHGHVAPMKGAMK
EEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCHHHHHH
ALGIDPNRLDVVLMQLVKLIEGGQVVRMSKRTGKMITLRDLIEEVGKDAARFFFNMRSPD
HHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCHHHHHHEECCCCC
SPIEFDLDLAKQQTNENPVFYVQYAHARICSIIRQLEEMGVKIENIEDVDLGLLKEEEEV
CCCEECHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHH
DLIKKLAYFPEEITIAAKTLAPHRITRYVIDVASLFHSFYNSHRVKGAEENLMKARFALI
HHHHHHHHCCCHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAVKTVLKNALDILKVTAPERM
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336