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The map label for this gene is ZntA [H]

Identifier: 20808818

GI number: 20808818

Start: 2351206

End: 2353596

Strand: Reverse

Name: ZntA [H]

Synonym: TTE2463

Alternate gene names: 20808818

Gene position: 2353596-2351206 (Counterclockwise)

Preceding gene: 20808819

Following gene: 20808817

Centisome position: 87.51

GC content: 36.43

Gene sequence:

>2391_bases
ATGGCCGAAAAAGCTAATTTAAAAATAACTGGGATGTCTTGTGCAGCTTGTGCAACCAAAATAGAAAAAGGGCTTAAAAG
CTTAGATGGAGTTTTAGACGCAAATGTAAATCTTGCCGTTGAAAAAGCAACAGTTATATATGATCCAGATAAAATTAATA
TATGCGATATTGAGAAAAAGATAGAAGATATAGGATATGGTGTAATAAAAGATAAAGTAGAGCTTGCACTTATGGGTATG
TCCTGCGCATCCTGCGCTGCCAAAATCGAAAAAACCTTAAAAAACCTGCCTGGTGTAAGCAATGCATCAGTTAATTTTGC
AGCTGAGACGGCAATTGTCGAATATGATTCAAATGAAATTGATACAGAAAAAATGATTAAAGCGATAAAAGATATAGGAT
ATGATGCAAAAGAAAAGACTGGAGTAGGTATTGACACAGAAAAAGAGATAAAGGAGAGAGAAATAAATACATTAAGGAAA
CTTGTAATATATTCAGCGATTTTAACTGTGCCGTTAGTAATATCAATGGTTTTGAGAATGTTTAAAATTTCAGGTGGAAT
ACTTGATAATCCATGGTTACAGGTATTTTTATCTTCACCTGTTCAGTTTATTGTAGGTTTTAGATATTATAAAGGTGCTT
GGAACAATTTAAAAAATATGACGGCAAATATGGATACTTTGGTAGCTATGGGAACATCTGCAGCATATTTTTATAGTTTG
TACAATGTATTTACTAAACCCTCTCATGAGATACACAATTACTTGTATTTTGAGGCATCAGCAGTTATTATAACGCTTGT
AACATTAGGTAAGCTGCTTGAAGCTATAGCCAAGGGAAAAACGTCTGAAGCAATAAAAAACCTCATGGGACTACAAGCAA
AGACCGCAAGAGTGATAAGGGATGGGCAAGAATTAGATATACCTATTGAAGAAGTCAAAGTCGGGGATATCGTTGTTGTA
AGGCCGGGCGAAAAAATACCAGTTGACGGTAAAATAGTTGAGGGTAGTTCCACAATAGATGAATCTATGATAACTGGTGA
ATCTATTCCTGTAGAAAAAGGCGTTGGTGATGAAGTAATTGGCGCTACGATAAATAAAACAGGAACGTTTAAATTTGAAG
CGACAAAAGTGGGTAAAGATACGGTACTATCGCAAATTATTAAAATGGTAGAAGATGCCCAAGGATCAAAAGCGCCAATT
CAACAAATTGCTGATAAAATCTCTGGTATTTTTGTACCCACAGTTATAGCCATAGCTGCTACCACATTTTTAATTTGGTA
TTTTGGGTATGGAGATTTTAATGCGGGCATAATAAATGCAGTATCAGTACTTGTAATTGCCTGCCCGTGTGCGCTTGGAC
TTGCAGTTCCCACTTCTGTGATGGTAGGGACAGGAAAAGGAGCAGAAAATGGTATACTCATAAAGGGAGGAGAACATCTG
CAGAGGGCAGGGAAAATAACGGCAATAGTATTTGATAAGACTGGGACGATAACAAAAGGAGAACCGGAAGTTACAGACAT
AGTAACTTTTGGAGATTTCACCGAAGATGAGATTTTGAAAATTGCGGGAATTGCGGAAAAAAATTCTGAGCATCCATTGG
GACAAGCAATTGTCAATAAAGCAAAAGAAAAATTCAAAATATTGGAAGACCCTGAGAAATTTGAGGCTGTACCAGGCTAT
GGTATATGCATTACGATAAATGAAAAAGAGTTTTATATTGGCAATAGAAGGCTCATGGACAGACAAAATATTGATATAAC
GTCAATTGAAGATAAGGTTGAAGAACTAGAATTACAAGGTAAAACAGCAATGATATTGGCATCTCACGACAGAGTTTATG
GCATTATAGCTGTTGCAGATACTGTAAAGAGTGACTCGGCAAAAGCAATTCAAAAGTTACAAGCTATGGGTATTGAAGTA
TACATGATTACGGGAGATAATAAAAGGACTGCTGAGGCAATAGCAAAACAAGTTGGTATAAAAAATGTGTTGGCAGAAGT
ATTGCCAGAACATAAGGCTTTGGAGATTATGAAGCTTCAAAAAATGGGAAAAGTAGTTGCAATGGTGGGAGATGGTATTA
ATGATGCTCCTGCTTTAGCTACTGCGGATGTTGGCATAGCGATAGGTACAGGTACAGATGTGGCGATAGAAACCTCAGAT
ATAACGCTTTTAAGTGGAAATCTTATGGGTATTGTGACCGCTATAAAATTAAGCAAAGCTACGATGAGAAATATATATCA
AAATTTATTCTGGGCTTTTGTATACAATACAATCGGCATACCATTTGCTGCGATGGGCCTTTTAACTCCAGCTATAGCAG
GAGGGGCAATGGCATTTAGCTCAGTGTCAGTTGTAACAAATGCTTTAAGACTGAGAAGATTTAAAGTATAA

Upstream 100 bases:

>100_bases
GCGGAATAATAGAAAGAAAAGTTAGATAAAATTTTGGAATTTCCTTTTATGTGGAAGAATTTCCTATAAGAATACTGAGA
GATGAAGAGGAGATGAAAAT

Downstream 100 bases:

>100_bases
GTTAAAATCATGTTATGCTAAGCTTTAGAACAAAGGAGTATGGGGATTATGGAGGAAAAGATTTTAAATAAATTTTGTGA
AAGTGCCGCTATGGTTTAAG

Product: cation transport ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MAEKANLKITGMSCAACATKIEKGLKSLDGVLDANVNLAVEKATVIYDPDKINICDIEKKIEDIGYGVIKDKVELALMGM
SCASCAAKIEKTLKNLPGVSNASVNFAAETAIVEYDSNEIDTEKMIKAIKDIGYDAKEKTGVGIDTEKEIKEREINTLRK
LVIYSAILTVPLVISMVLRMFKISGGILDNPWLQVFLSSPVQFIVGFRYYKGAWNNLKNMTANMDTLVAMGTSAAYFYSL
YNVFTKPSHEIHNYLYFEASAVIITLVTLGKLLEAIAKGKTSEAIKNLMGLQAKTARVIRDGQELDIPIEEVKVGDIVVV
RPGEKIPVDGKIVEGSSTIDESMITGESIPVEKGVGDEVIGATINKTGTFKFEATKVGKDTVLSQIIKMVEDAQGSKAPI
QQIADKISGIFVPTVIAIAATTFLIWYFGYGDFNAGIINAVSVLVIACPCALGLAVPTSVMVGTGKGAENGILIKGGEHL
QRAGKITAIVFDKTGTITKGEPEVTDIVTFGDFTEDEILKIAGIAEKNSEHPLGQAIVNKAKEKFKILEDPEKFEAVPGY
GICITINEKEFYIGNRRLMDRQNIDITSIEDKVEELELQGKTAMILASHDRVYGIIAVADTVKSDSAKAIQKLQAMGIEV
YMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKALEIMKLQKMGKVVAMVGDGINDAPALATADVGIAIGTGTDVAIETSD
ITLLSGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAGGAMAFSSVSVVTNALRLRRFKV

Sequences:

>Translated_796_residues
MAEKANLKITGMSCAACATKIEKGLKSLDGVLDANVNLAVEKATVIYDPDKINICDIEKKIEDIGYGVIKDKVELALMGM
SCASCAAKIEKTLKNLPGVSNASVNFAAETAIVEYDSNEIDTEKMIKAIKDIGYDAKEKTGVGIDTEKEIKEREINTLRK
LVIYSAILTVPLVISMVLRMFKISGGILDNPWLQVFLSSPVQFIVGFRYYKGAWNNLKNMTANMDTLVAMGTSAAYFYSL
YNVFTKPSHEIHNYLYFEASAVIITLVTLGKLLEAIAKGKTSEAIKNLMGLQAKTARVIRDGQELDIPIEEVKVGDIVVV
RPGEKIPVDGKIVEGSSTIDESMITGESIPVEKGVGDEVIGATINKTGTFKFEATKVGKDTVLSQIIKMVEDAQGSKAPI
QQIADKISGIFVPTVIAIAATTFLIWYFGYGDFNAGIINAVSVLVIACPCALGLAVPTSVMVGTGKGAENGILIKGGEHL
QRAGKITAIVFDKTGTITKGEPEVTDIVTFGDFTEDEILKIAGIAEKNSEHPLGQAIVNKAKEKFKILEDPEKFEAVPGY
GICITINEKEFYIGNRRLMDRQNIDITSIEDKVEELELQGKTAMILASHDRVYGIIAVADTVKSDSAKAIQKLQAMGIEV
YMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKALEIMKLQKMGKVVAMVGDGINDAPALATADVGIAIGTGTDVAIETSD
ITLLSGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAGGAMAFSSVSVVTNALRLRRFKV
>Mature_795_residues
AEKANLKITGMSCAACATKIEKGLKSLDGVLDANVNLAVEKATVIYDPDKINICDIEKKIEDIGYGVIKDKVELALMGMS
CASCAAKIEKTLKNLPGVSNASVNFAAETAIVEYDSNEIDTEKMIKAIKDIGYDAKEKTGVGIDTEKEIKEREINTLRKL
VIYSAILTVPLVISMVLRMFKISGGILDNPWLQVFLSSPVQFIVGFRYYKGAWNNLKNMTANMDTLVAMGTSAAYFYSLY
NVFTKPSHEIHNYLYFEASAVIITLVTLGKLLEAIAKGKTSEAIKNLMGLQAKTARVIRDGQELDIPIEEVKVGDIVVVR
PGEKIPVDGKIVEGSSTIDESMITGESIPVEKGVGDEVIGATINKTGTFKFEATKVGKDTVLSQIIKMVEDAQGSKAPIQ
QIADKISGIFVPTVIAIAATTFLIWYFGYGDFNAGIINAVSVLVIACPCALGLAVPTSVMVGTGKGAENGILIKGGEHLQ
RAGKITAIVFDKTGTITKGEPEVTDIVTFGDFTEDEILKIAGIAEKNSEHPLGQAIVNKAKEKFKILEDPEKFEAVPGYG
ICITINEKEFYIGNRRLMDRQNIDITSIEDKVEELELQGKTAMILASHDRVYGIIAVADTVKSDSAKAIQKLQAMGIEVY
MITGDNKRTAEAIAKQVGIKNVLAEVLPEHKALEIMKLQKMGKVVAMVGDGINDAPALATADVGIAIGTGTDVAIETSDI
TLLSGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAGGAMAFSSVSVVTNALRLRRFKV

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=866, Percent_Identity=40.0692840646651, Blast_Score=587, Evalue=1e-167,
Organism=Homo sapiens, GI115529486, Length=903, Percent_Identity=38.8704318936877, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI55743073, Length=542, Percent_Identity=44.280442804428, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI48762687, Length=612, Percent_Identity=24.0196078431373, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI48762685, Length=612, Percent_Identity=24.0196078431373, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI48762689, Length=612, Percent_Identity=24.0196078431373, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI48762691, Length=612, Percent_Identity=24.0196078431373, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI28373107, Length=188, Percent_Identity=31.3829787234043, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI28373109, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI28373115, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI28373111, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI28373103, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI28373113, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI28373105, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI209413709, Length=188, Percent_Identity=31.3829787234043, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI24638454, Length=188, Percent_Identity=31.3829787234043, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI27886529, Length=188, Percent_Identity=32.4468085106383, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4502285, Length=188, Percent_Identity=31.3829787234043, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI10835220, Length=188, Percent_Identity=32.4468085106383, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310128958, Length=159, Percent_Identity=34.5911949685535, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI118498343, Length=184, Percent_Identity=32.6086956521739, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI4502271, Length=204, Percent_Identity=28.921568627451, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI153946397, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI21361181, Length=204, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI237681109, Length=204, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI237681111, Length=204, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI22748667, Length=204, Percent_Identity=26.9607843137255, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI51944966, Length=197, Percent_Identity=26.3959390862944, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI297374799, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI83700225, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1786691, Length=852, Percent_Identity=38.7323943661972, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1789879, Length=725, Percent_Identity=32, Blast_Score=338, Evalue=9e-94,
Organism=Escherichia coli, GI1786914, Length=514, Percent_Identity=31.1284046692607, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI2367363, Length=611, Percent_Identity=25.0409165302782, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17556548, Length=881, Percent_Identity=37.116912599319, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI71997262, Length=601, Percent_Identity=26.4559068219634, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71997275, Length=601, Percent_Identity=26.4559068219634, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71997269, Length=578, Percent_Identity=26.643598615917, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557486, Length=184, Percent_Identity=33.695652173913, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193210130, Length=187, Percent_Identity=31.5508021390374, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988506, Length=187, Percent_Identity=31.5508021390374, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17554158, Length=187, Percent_Identity=31.5508021390374, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32566766, Length=190, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17557770, Length=190, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203356, Length=183, Percent_Identity=31.1475409836066, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193203354, Length=183, Percent_Identity=31.1475409836066, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559224, Length=230, Percent_Identity=26.9565217391304, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531459, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71999370, Length=519, Percent_Identity=22.1579961464355, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71999372, Length=519, Percent_Identity=22.1579961464355, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=867, Percent_Identity=37.2549019607843, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6319772, Length=844, Percent_Identity=28.0805687203791, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6325221, Length=559, Percent_Identity=27.906976744186, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321430, Length=559, Percent_Identity=27.1914132379249, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321271, Length=174, Percent_Identity=37.9310344827586, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321432, Length=160, Percent_Identity=37.5, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320243, Length=196, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320244, Length=196, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320245, Length=298, Percent_Identity=24.8322147651007, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221329854, Length=909, Percent_Identity=32.7832783278328, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI17136664, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24762455, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762453, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762447, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762457, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762449, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762445, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24762451, Length=165, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668696, Length=167, Percent_Identity=34.7305389221557, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668708, Length=167, Percent_Identity=34.7305389221557, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161085803, Length=167, Percent_Identity=34.7305389221557, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366617, Length=167, Percent_Identity=34.7305389221557, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668704, Length=167, Percent_Identity=34.7305389221557, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366676, Length=232, Percent_Identity=26.2931034482759, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648582, Length=236, Percent_Identity=25.4237288135593, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45553441, Length=210, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648580, Length=210, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648578, Length=210, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553435, Length=318, Percent_Identity=24.2138364779874, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553439, Length=318, Percent_Identity=24.2138364779874, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362164, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648576, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553437, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 85713; Mature: 85582

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKANLKITGMSCAACATKIEKGLKSLDGVLDANVNLAVEKATVIYDPDKINICDIEKK
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHH
IEDIGYGVIKDKVELALMGMSCASCAAKIEKTLKNLPGVSNASVNFAAETAIVEYDSNEI
HHHCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCC
DTEKMIKAIKDIGYDAKEKTGVGIDTEKEIKEREINTLRKLVIYSAILTVPLVISMVLRM
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKISGGILDNPWLQVFLSSPVQFIVGFRYYKGAWNNLKNMTANMDTLVAMGTSAAYFYSL
HHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCHHHHHHHH
YNVFTKPSHEIHNYLYFEASAVIITLVTLGKLLEAIAKGKTSEAIKNLMGLQAKTARVIR
HHHHCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHC
DGQELDIPIEEVKVGDIVVVRPGEKIPVDGKIVEGSSTIDESMITGESIPVEKGVGDEVI
CCCCCCCCHHHEEECCEEEECCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCHHH
GATINKTGTFKFEATKVGKDTVLSQIIKMVEDAQGSKAPIQQIADKISGIFVPTVIAIAA
CCEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
TTFLIWYFGYGDFNAGIINAVSVLVIACPCALGLAVPTSVMVGTGKGAENGILIKGGEHL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHH
QRAGKITAIVFDKTGTITKGEPEVTDIVTFGDFTEDEILKIAGIAEKNSEHPLGQAIVNK
HHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCHHHHHHHH
AKEKFKILEDPEKFEAVPGYGICITINEKEFYIGNRRLMDRQNIDITSIEDKVEELELQG
HHHHHHCCCCHHHHCCCCCCEEEEEECCCEEEECCCEECCCCCCCEEHHHHHHHHHHHCC
KTAMILASHDRVYGIIAVADTVKSDSAKAIQKLQAMGIEVYMITGDNKRTAEAIAKQVGI
CEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCH
KNVLAEVLPEHKALEIMKLQKMGKVVAMVGDGINDAPALATADVGIAIGTGTDVAIETSD
HHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCCCEEEECCCCEEEEECC
ITLLSGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAGGAMAFS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
SVSVVTNALRLRRFKV
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEKANLKITGMSCAACATKIEKGLKSLDGVLDANVNLAVEKATVIYDPDKINICDIEKK
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHH
IEDIGYGVIKDKVELALMGMSCASCAAKIEKTLKNLPGVSNASVNFAAETAIVEYDSNEI
HHHCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCC
DTEKMIKAIKDIGYDAKEKTGVGIDTEKEIKEREINTLRKLVIYSAILTVPLVISMVLRM
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKISGGILDNPWLQVFLSSPVQFIVGFRYYKGAWNNLKNMTANMDTLVAMGTSAAYFYSL
HHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCHHHHHHHH
YNVFTKPSHEIHNYLYFEASAVIITLVTLGKLLEAIAKGKTSEAIKNLMGLQAKTARVIR
HHHHCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHC
DGQELDIPIEEVKVGDIVVVRPGEKIPVDGKIVEGSSTIDESMITGESIPVEKGVGDEVI
CCCCCCCCHHHEEECCEEEECCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCHHH
GATINKTGTFKFEATKVGKDTVLSQIIKMVEDAQGSKAPIQQIADKISGIFVPTVIAIAA
CCEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
TTFLIWYFGYGDFNAGIINAVSVLVIACPCALGLAVPTSVMVGTGKGAENGILIKGGEHL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHH
QRAGKITAIVFDKTGTITKGEPEVTDIVTFGDFTEDEILKIAGIAEKNSEHPLGQAIVNK
HHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCHHHHHHHH
AKEKFKILEDPEKFEAVPGYGICITINEKEFYIGNRRLMDRQNIDITSIEDKVEELELQG
HHHHHHCCCCHHHHCCCCCCEEEEEECCCEEEECCCEECCCCCCCEEHHHHHHHHHHHCC
KTAMILASHDRVYGIIAVADTVKSDSAKAIQKLQAMGIEVYMITGDNKRTAEAIAKQVGI
CEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCH
KNVLAEVLPEHKALEIMKLQKMGKVVAMVGDGINDAPALATADVGIAIGTGTDVAIETSD
HHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCCCEEEECCCCEEEEECC
ITLLSGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAGGAMAFS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
SVSVVTNALRLRRFKV
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA