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The map label for this gene is MazG [H]

Identifier: 20808811

GI number: 20808811

Start: 2341145

End: 2342644

Strand: Reverse

Name: MazG [H]

Synonym: TTE2454

Alternate gene names: 20808811

Gene position: 2342644-2341145 (Counterclockwise)

Preceding gene: 20808814

Following gene: 20808810

Centisome position: 87.11

GC content: 38.67

Gene sequence:

>1500_bases
GTGAGCGAACTAGCTATAGTAGGATTGGGATCAGGGTCAATGGACAGTTTGACAGTAGGAGCTTTAAAGAAATTGGAAGA
AGCTGAGCGGATTTTTCTAAGGACTGCCAAGCATTCTGTTGTGAAAGAGCTGGAAAAGAAGGGCTTTATTTTCGAAACTT
TTGACAGTTTTTATGAAAAGTACGAGACTTTTGAAGAAGTGTATGAGAATATAGCACGAGAGGTTATAGAAAAGGCAAAA
AAATATCAAAAAGTAGTTTATGCGGTTCCTGGACATCCATATGTGGGCGAAAAAACTGTAGAGTACATATTAAACTTTTG
CGATGGATGTGCCGATATATCAATAGAACTGGTTCCTGCGGTTTCATCAATTGATGCGATTTTGAACGATTTGAAGGTTG
ACCCTGTGGAAGGATTAAAAATAATTGATGCTCTCTCTCTAAGTGAGCAAAGGCCGGATAAGAGATGCCACAATATAGTG
CTGCAGGTTTATGATAAGTTTGTTGCATCAGAAGTGAAATTGAAGCTGGCAGAAGTTTATGGAGATACTCATGAAGTGGT
AGTTATAAAAAACGCTGGGATGAGGGATCGAAAAATTGAAAAAGTGCCTATATACGAGATTGACAGGTTAGATTGGATTG
ATTATTTGACTTCTCTGTACATTCCTCCTGTAAAAGGATTTTTTCAGGAAAAATACGATATATACGACCTTTTGGATATA
ATGAAGGCTTTGAGGGCTGAGGATGGATGCCCTTGGGATAGGGAACAAACCCATAAGACTTTAGAGAAGTACTTAATTGA
AGAAAGCTATGAGCTAGTTGATGCCATTGAAAAAGAGGCAGAGGACAAAATGGTGGAAGAGCTGGGAGATGTCCTTTTGC
AGGTGGTTTTCCACTCTCAAATAGCGGCGGAAAGGGGAACATTCGACTTTGGAGAAGTTGTAGATAGAATATGCAAAAAG
ATGATTTGGCGCCATCCCCACGTTTTTGGCGAAGAAAAGGTAAAAAATTCTCAGGAAGTTTTGGACAAGTGGGAAAAATT
AAAATGGGAAGAGAAAAAAAGAGAAGAAAAGGAACTTAATTCTTACACGGATGTTTTGAGGGATGTGCCAAGGTATGTGC
CTGCTTTGATGAGAAGTTTTAAGGTGCAGGAAAAGGCTTCAAGGGTGGGGTTTGATTGGGATCGGGTTGAGGAGGCGTTT
TCAAAAATTTATGAAGAATTAGAGGAATTAAAGGAGGTGTATAAAGGAGAAAATAAGGAAAAGATAAAGGAAGAGATAGG
TGATTTGATCTTTGCGGTAGTCAATGTGGCAAGGTTTTTAGATGTGGACCCTGAACAAGCTACTCATCAGACGGTTGAGA
AGTTTATTGAGAGGTTTTCCTATATAGAGAGGGAAGCCAGAAAGAAAGGCATGAAGTTGGAAAATATGACATTAAGTGAC
ATGGATGCTCTTTGGAATGAGGCGAAGGCGAATAATTTTAATAAAAAAAATGAAAAATAA

Upstream 100 bases:

>100_bases
GCAACTTTTTCAACAGGGGAGAAAAGAAAAAATTTAACTATATAAAAAATACTGAAAGTGATATAATATTATCCGTAAAC
ACTTTCTCGGGGTGATATTT

Downstream 100 bases:

>100_bases
GCTTAAATTAGCAGGATTTTTCGATTTTGTGAAGAATAAATAAAAAGTAAAAGTATATTTAAAAATAACGAAGGAGGGTA
TTGATTGTGAATAAGGCAGA

Product: pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSELAIVGLGSGSMDSLTVGALKKLEEAERIFLRTAKHSVVKELEKKGFIFETFDSFYEKYETFEEVYENIAREVIEKAK
KYQKVVYAVPGHPYVGEKTVEYILNFCDGCADISIELVPAVSSIDAILNDLKVDPVEGLKIIDALSLSEQRPDKRCHNIV
LQVYDKFVASEVKLKLAEVYGDTHEVVVIKNAGMRDRKIEKVPIYEIDRLDWIDYLTSLYIPPVKGFFQEKYDIYDLLDI
MKALRAEDGCPWDREQTHKTLEKYLIEESYELVDAIEKEAEDKMVEELGDVLLQVVFHSQIAAERGTFDFGEVVDRICKK
MIWRHPHVFGEEKVKNSQEVLDKWEKLKWEEKKREEKELNSYTDVLRDVPRYVPALMRSFKVQEKASRVGFDWDRVEEAF
SKIYEELEELKEVYKGENKEKIKEEIGDLIFAVVNVARFLDVDPEQATHQTVEKFIERFSYIEREARKKGMKLENMTLSD
MDALWNEAKANNFNKKNEK

Sequences:

>Translated_499_residues
MSELAIVGLGSGSMDSLTVGALKKLEEAERIFLRTAKHSVVKELEKKGFIFETFDSFYEKYETFEEVYENIAREVIEKAK
KYQKVVYAVPGHPYVGEKTVEYILNFCDGCADISIELVPAVSSIDAILNDLKVDPVEGLKIIDALSLSEQRPDKRCHNIV
LQVYDKFVASEVKLKLAEVYGDTHEVVVIKNAGMRDRKIEKVPIYEIDRLDWIDYLTSLYIPPVKGFFQEKYDIYDLLDI
MKALRAEDGCPWDREQTHKTLEKYLIEESYELVDAIEKEAEDKMVEELGDVLLQVVFHSQIAAERGTFDFGEVVDRICKK
MIWRHPHVFGEEKVKNSQEVLDKWEKLKWEEKKREEKELNSYTDVLRDVPRYVPALMRSFKVQEKASRVGFDWDRVEEAF
SKIYEELEELKEVYKGENKEKIKEEIGDLIFAVVNVARFLDVDPEQATHQTVEKFIERFSYIEREARKKGMKLENMTLSD
MDALWNEAKANNFNKKNEK
>Mature_498_residues
SELAIVGLGSGSMDSLTVGALKKLEEAERIFLRTAKHSVVKELEKKGFIFETFDSFYEKYETFEEVYENIAREVIEKAKK
YQKVVYAVPGHPYVGEKTVEYILNFCDGCADISIELVPAVSSIDAILNDLKVDPVEGLKIIDALSLSEQRPDKRCHNIVL
QVYDKFVASEVKLKLAEVYGDTHEVVVIKNAGMRDRKIEKVPIYEIDRLDWIDYLTSLYIPPVKGFFQEKYDIYDLLDIM
KALRAEDGCPWDREQTHKTLEKYLIEESYELVDAIEKEAEDKMVEELGDVLLQVVFHSQIAAERGTFDFGEVVDRICKKM
IWRHPHVFGEEKVKNSQEVLDKWEKLKWEEKKREEKELNSYTDVLRDVPRYVPALMRSFKVQEKASRVGFDWDRVEEAFS
KIYEELEELKEVYKGENKEKIKEEIGDLIFAVVNVARFLDVDPEQATHQTVEKFIERFSYIEREARKKGMKLENMTLSDM
DALWNEAKANNFNKKNEK

Specific function: Unknown

COG id: COG3956

COG function: function code R; Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789144, Length=258, Percent_Identity=43.4108527131783, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR004518
- InterPro:   IPR011551 [H]

Pfam domain/function: PF03819 MazG; PF00590 TP_methylase [H]

EC number: NA

Molecular weight: Translated: 58206; Mature: 58075

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELAIVGLGSGSMDSLTVGALKKLEEAERIFLRTAKHSVVKELEKKGFIFETFDSFYEK
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YETFEEVYENIAREVIEKAKKYQKVVYAVPGHPYVGEKTVEYILNFCDGCADISIELVPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHH
VSSIDAILNDLKVDPVEGLKIIDALSLSEQRPDKRCHNIVLQVYDKFVASEVKLKLAEVY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDTHEVVVIKNAGMRDRKIEKVPIYEIDRLDWIDYLTSLYIPPVKGFFQEKYDIYDLLDI
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MKALRAEDGCPWDREQTHKTLEKYLIEESYELVDAIEKEAEDKMVEELGDVLLQVVFHSQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAERGTFDFGEVVDRICKKMIWRHPHVFGEEKVKNSQEVLDKWEKLKWEEKKREEKELN
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
SYTDVLRDVPRYVPALMRSFKVQEKASRVGFDWDRVEEAFSKIYEELEELKEVYKGENKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIKEEIGDLIFAVVNVARFLDVDPEQATHQTVEKFIERFSYIEREARKKGMKLENMTLSD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MDALWNEAKANNFNKKNEK
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SELAIVGLGSGSMDSLTVGALKKLEEAERIFLRTAKHSVVKELEKKGFIFETFDSFYEK
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YETFEEVYENIAREVIEKAKKYQKVVYAVPGHPYVGEKTVEYILNFCDGCADISIELVPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHH
VSSIDAILNDLKVDPVEGLKIIDALSLSEQRPDKRCHNIVLQVYDKFVASEVKLKLAEVY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDTHEVVVIKNAGMRDRKIEKVPIYEIDRLDWIDYLTSLYIPPVKGFFQEKYDIYDLLDI
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MKALRAEDGCPWDREQTHKTLEKYLIEESYELVDAIEKEAEDKMVEELGDVLLQVVFHSQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAERGTFDFGEVVDRICKKMIWRHPHVFGEEKVKNSQEVLDKWEKLKWEEKKREEKELN
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
SYTDVLRDVPRYVPALMRSFKVQEKASRVGFDWDRVEEAFSKIYEELEELKEVYKGENKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIKEEIGDLIFAVVNVARFLDVDPEQATHQTVEKFIERFSYIEREARKKGMKLENMTLSD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MDALWNEAKANNFNKKNEK
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]