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The map label for this gene is SerB [H]

Identifier: 20808805

GI number: 20808805

Start: 2337684

End: 2338349

Strand: Reverse

Name: SerB [H]

Synonym: TTE2448

Alternate gene names: 20808805

Gene position: 2338349-2337684 (Counterclockwise)

Preceding gene: 20808806

Following gene: 20808803

Centisome position: 86.95

GC content: 34.53

Gene sequence:

>666_bases
GTGGCTCTTAAAAGGATGAAGGGAGAGGAGCAGATGAAAAAAGTTTTTTTGGTGGATTTTGATGGAACTGTGACCAAAAA
AGATGCTGTCTACATGATGGTAGAGAAGTTTGCAAAGGAAGGTTGGCAGTATTACAATGAGTTGTGGGAAAAAGGAGAGA
TGTCTACAGAAGAGTGTGCTATTGAGACTTTAAAGCTAATGGAAGTGTCTGAAGAAGAGCTTTTTAAATTTATAATGGAA
AATGTAGAAATAGATGACCATTTCCTGGAGTTTTTAGGGGTAACAAAAGAAAAAGAATATGAAGTAGTTATTGTCAGCGA
TGGATACGATTTTATAATAGAGGCGGTGATGAAAAAGTATAATTTAAAACTTCCCTACTATAGCAATAAAATGTGGTTTG
AAGGGGGAAAAATAAAAGTAGCTTTTCCCTATAAAGATAAAGAGTGCGATAAATGTGGAATGTGTAAACTCAATATTTTA
AAAGAGTACAGAAAAAAGGGATATAGTGTTGCCTTTGTAGGAGATGGGTATTCTGATTTCTGTGTGGTGGAACATGCTGA
TGAGGTTTTTGCTAAAGACGTGTTAGCAGATTACTGCGAGGAAAAAGGAATTAAATATTTTCGATTTGGTAGCTTCAAAG
ACATAATAAGATATGTAAAGCGATAA

Upstream 100 bases:

>100_bases
ATAATCGATGGTTAAAGCAAATTGGCTATGACTATCATGACAAGATAATTGCAGTTCTTTCTAATTCGGAACATAAAGAT
CTGGCGATAAAATTTGTGAA

Downstream 100 bases:

>100_bases
ACACTAATGAGTGTTTATCGCTTTTACAAGAGGGGGAAGTACCTGCTTTTTGCGAGAAATCACGTAAGGAAGATAGAAAC
TGTTGTTTTGTATCTTTACA

Product: phosphoserine phosphatase

Products: L-serine; D-serine; phosphate

Alternate protein names: HK-MTPenyl-1-P phosphatase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MALKRMKGEEQMKKVFLVDFDGTVTKKDAVYMMVEKFAKEGWQYYNELWEKGEMSTEECAIETLKLMEVSEEELFKFIME
NVEIDDHFLEFLGVTKEKEYEVVIVSDGYDFIIEAVMKKYNLKLPYYSNKMWFEGGKIKVAFPYKDKECDKCGMCKLNIL
KEYRKKGYSVAFVGDGYSDFCVVEHADEVFAKDVLADYCEEKGIKYFRFGSFKDIIRYVKR

Sequences:

>Translated_221_residues
MALKRMKGEEQMKKVFLVDFDGTVTKKDAVYMMVEKFAKEGWQYYNELWEKGEMSTEECAIETLKLMEVSEEELFKFIME
NVEIDDHFLEFLGVTKEKEYEVVIVSDGYDFIIEAVMKKYNLKLPYYSNKMWFEGGKIKVAFPYKDKECDKCGMCKLNIL
KEYRKKGYSVAFVGDGYSDFCVVEHADEVFAKDVLADYCEEKGIKYFRFGSFKDIIRYVKR
>Mature_220_residues
ALKRMKGEEQMKKVFLVDFDGTVTKKDAVYMMVEKFAKEGWQYYNELWEKGEMSTEECAIETLKLMEVSEEELFKFIMEN
VEIDDHFLEFLGVTKEKEYEVVIVSDGYDFIIEAVMKKYNLKLPYYSNKMWFEGGKIKVAFPYKDKECDKCGMCKLNILK
EYRKKGYSVAFVGDGYSDFCVVEHADEVFAKDVLADYCEEKGIKYFRFGSFKDIIRYVKR

Specific function: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) [H]

COG id: COG4359

COG function: function code E; Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MtnX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR006384 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.3

Molecular weight: Translated: 26156; Mature: 26024

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKRMKGEEQMKKVFLVDFDGTVTKKDAVYMMVEKFAKEGWQYYNELWEKGEMSTEECA
CCCCCCCCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IETLKLMEVSEEELFKFIMENVEIDDHFLEFLGVTKEKEYEVVIVSDGYDFIIEAVMKKY
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH
NLKLPYYSNKMWFEGGKIKVAFPYKDKECDKCGMCKLNILKEYRKKGYSVAFVGDGYSDF
CCCCCEECCEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCE
CVVEHADEVFAKDVLADYCEEKGIKYFRFGSFKDIIRYVKR
EEEHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
ALKRMKGEEQMKKVFLVDFDGTVTKKDAVYMMVEKFAKEGWQYYNELWEKGEMSTEECA
CCCCCCCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IETLKLMEVSEEELFKFIMENVEIDDHFLEFLGVTKEKEYEVVIVSDGYDFIIEAVMKKY
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH
NLKLPYYSNKMWFEGGKIKVAFPYKDKECDKCGMCKLNILKEYRKKGYSVAFVGDGYSDF
CCCCCEECCEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCE
CVVEHADEVFAKDVLADYCEEKGIKYFRFGSFKDIIRYVKR
EEEHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-O-phosphoserine; D-O-phosphoserine; H2O

Specific reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA