BacMap

Definition	Thermoanaerobacter tengcongensis MB4, complete genome.
Accession	NC_003869
Length	2,689,445

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The map label for this gene is HflB3 [H]

Identifier: 20808757

GI number: 20808757

Start: 2281312

End: 2283147

Strand: Reverse

Name: HflB3 [H]

Synonym: TTE2393

Alternate gene names: 20808757

Gene position: 2283147-2281312 (Counterclockwise)

Preceding gene: 20808758

Following gene: 20808756

Centisome position: 84.89

GC content: 44.28

Gene sequence:

>1836_bases
TTGAAAGATAACAATAAAATTTTCAGGAGCATGGTACTTTATCTCCTCATTTTCATAGCTATATATGCGATGGTACAGCT
TTATTCCCAAGCTACGCCTCAGGTAACTAAAATAGACTACGGAGAGCTGGTAAGGTATATAAGTGCAAATCAGATAAAAA
GTATTACTCTTTCGGGCAATCAGGTGAAAGGCGTATTCAAAAACGGCACCGAGTTTGAAAGCAGTGTGCCTGATATAACC
AATTTTATGTCTTTTGTGGACCCGTATATATTGGAAGGCAAACTGGATTTTAAATATGAGCCCCAGGTGGGACCGCCTTG
GTGGGTTCAGATGCTTCCTTCCCTGTTCTTGGTAGGTGTGCTCATTCTCTTCTGGTATATATTTATGCAGCAAGCACAGG
GCGGGGGAGGAAGCAGGGTGATGTCTTTTGGCAAGAGCAGAGCTAGAATGGTTACAGATAAGGACAAAAGAGTTACTTTT
AATGATGTGGCGGGTGCAGATGAAGAAAAAGAAGAACTCCAAGAGATTGTAGAGTTTTTGAAATATCCAAAAAAATTTAT
TGAATTAGGGGCGAGAATTCCTAAAGGAGTGCTTTTAGTAGGTCCACCGGGCACGGGGAAGACTCTTCTGGCAAGAGCTG
TTGCAGGAGAGGCAGGGGTTCCCTTTTTCAGCATAAGCGGTTCTGACTTTGTGGAGATGTTTGTGGGTGTGGGTGCAGCG
AGAGTAAGAGACCTTTTTGAGCAGGCGAAGAAAAACGCACCTTGTATAGTGTTTATAGATGAGATAGATGCTGTAGGTAG
GCAGAGAGGGGCAGGTCTGGGCGGAGGGCATGACGAGAGAGAGCAAACGTTGAACCAGTTATTGGTTGAGATGGACGGAT
TTAGTGTAAATGAAGGGATAATCGTAATTGCAGCTACAAACAGGCCTGATATACTGGATCCCGCCCTTTTAAGGCCTGGG
AGGTTTGACAGGCATATTGTGGTCAATATTCCTGACATAAAAGGGAGAGAAGAAATTTTGAAAGTCCATGCTAGAAATAA
ACCTCTGGCGCCTGACGTGTCCCTTCAAGTTATTGCCAGGAGGACGCCGGGCTTTACAGGGGCTGACCTAGAAAATGTGA
TGAATGAGGCAGCTCTGCTGGCGGCAAGAAAGGGTTTAAAGCAGATAACCATGGCAGAATTGGAGGAAGCTATCACCAGA
GTCGTAGCTGGGCCTGAAAAAAGGAGTAGAATCATGTCTGAAAAAGACAAAAAATTGGTAGCCTATCACGAAGCAGGGCA
TGCTGTTGTTGCGAAGCTTTTGCCCACGACTCCGCCTGTTCACGAGGTTACCATCATTCCAAGAGGGAGAGCTGGAGGTT
ACACGATGCTTCTCCCCGAAGAAGACAAGTACTACATGTCAAAGTCAGAGATGATGGATGAAATAGTTCACCTTTTGGGA
GGGCGCGCTGCTGAGAAGTTGGTGCTAAATGATATAAGCACTGGCGCTCAGAATGATATAGAAAGAGCTACCAATATTGC
CAGGAAAATGGTGACAGAGTATGGAATGAGCGACAGATTAGGTCCTATGACTTTTGGCACAAAAAGCGAAGAAGTGTTTT
TAGGAAGGGATTTAGGAAGGACGAGAAACTACAGTGAGGAAGTGGCTGCAGAGATAGACAGAGAGATAAGGAGAATAATA
GAGGAAGCTTATAAGAGAGCGGAAAGCCTTCTACAAGAGAATATAGATAAACTTCACAGAGTGGCGAAGGCCCTTATGGA
AAAAGAGAAGCTCAATGGAGAAGAGTTTGAAAAAGTATTTAATGGAGAAGAAATAGAAGGGGTTTCTTTTGCCTGA

Upstream 100 bases:

>100_bases
GGGGTTTTAAAGCCAGAGCTTTATAAATGATTTGGTTTTTTGTTCTTTATATGGTATTATAGATTAAAGTAGTGGGACTT
GTTTGAAGGAGGGGCCTTAT

Downstream 100 bases:

>100_bases
ATTGTATAAGTCGCAAGACTTATACAATTTTTTTTATAAAAACTTTAGTTAACAATAAAAAAATTATTGAAAAGAAGAAG
GAATTTTGCCTGTTTATGTC

Product: ATP-dependent Zn protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MKDNNKIFRSMVLYLLIFIAIYAMVQLYSQATPQVTKIDYGELVRYISANQIKSITLSGNQVKGVFKNGTEFESSVPDIT
NFMSFVDPYILEGKLDFKYEPQVGPPWWVQMLPSLFLVGVLILFWYIFMQQAQGGGGSRVMSFGKSRARMVTDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFIELGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHIVVNIPDIKGREEILKVHARNKPLAPDVSLQVIARRTPGFTGADLENVMNEAALLAARKGLKQITMAELEEAITR
VVAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPTTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRAAEKLVLNDISTGAQNDIERATNIARKMVTEYGMSDRLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIRRII
EEAYKRAESLLQENIDKLHRVAKALMEKEKLNGEEFEKVFNGEEIEGVSFA

Sequences:

>Translated_611_residues
MKDNNKIFRSMVLYLLIFIAIYAMVQLYSQATPQVTKIDYGELVRYISANQIKSITLSGNQVKGVFKNGTEFESSVPDIT
NFMSFVDPYILEGKLDFKYEPQVGPPWWVQMLPSLFLVGVLILFWYIFMQQAQGGGGSRVMSFGKSRARMVTDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFIELGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHIVVNIPDIKGREEILKVHARNKPLAPDVSLQVIARRTPGFTGADLENVMNEAALLAARKGLKQITMAELEEAITR
VVAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPTTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRAAEKLVLNDISTGAQNDIERATNIARKMVTEYGMSDRLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIRRII
EEAYKRAESLLQENIDKLHRVAKALMEKEKLNGEEFEKVFNGEEIEGVSFA
>Mature_611_residues
MKDNNKIFRSMVLYLLIFIAIYAMVQLYSQATPQVTKIDYGELVRYISANQIKSITLSGNQVKGVFKNGTEFESSVPDIT
NFMSFVDPYILEGKLDFKYEPQVGPPWWVQMLPSLFLVGVLILFWYIFMQQAQGGGGSRVMSFGKSRARMVTDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFIELGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHIVVNIPDIKGREEILKVHARNKPLAPDVSLQVIARRTPGFTGADLENVMNEAALLAARKGLKQITMAELEEAITR
VVAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPTTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRAAEKLVLNDISTGAQNDIERATNIARKMVTEYGMSDRLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIRRII
EEAYKRAESLLQENIDKLHRVAKALMEKEKLNGEEFEKVFNGEEIEGVSFA

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=495, Percent_Identity=48.4848484848485, Blast_Score=454, Evalue=1e-127,
Organism=Homo sapiens, GI4507173, Length=498, Percent_Identity=44.7791164658635, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI7657689, Length=453, Percent_Identity=47.9028697571744, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI21327685, Length=453, Percent_Identity=47.9028697571744, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4506209, Length=246, Percent_Identity=45.9349593495935, Blast_Score=226, Evalue=7e-59,
Organism=Homo sapiens, GI24497435, Length=254, Percent_Identity=44.4881889763779, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=45.575221238938, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI21361144, Length=252, Percent_Identity=45.2380952380952, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=40, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=40.5511811023622, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=40.3636363636364, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=40.3636363636364, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=43.1111111111111, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI89064750, Length=259, Percent_Identity=38.996138996139, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI5729991, Length=259, Percent_Identity=38.996138996139, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI229577436, Length=259, Percent_Identity=41.6988416988417, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI24430155, Length=259, Percent_Identity=38.996138996139, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI40806173, Length=194, Percent_Identity=51.0309278350515, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4505725, Length=229, Percent_Identity=41.0480349344978, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI24497618, Length=244, Percent_Identity=41.8032786885246, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=41.3223140495868, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI14149767, Length=254, Percent_Identity=37.7952755905512, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI62177112, Length=254, Percent_Identity=37.7952755905512, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI5901990, Length=254, Percent_Identity=39.7637795275591, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI194018488, Length=235, Percent_Identity=41.2765957446808, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI226371754, Length=259, Percent_Identity=36.2934362934363, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI7019569, Length=237, Percent_Identity=37.1308016877637, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI31377644, Length=283, Percent_Identity=35.3356890459364, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI17865802, Length=237, Percent_Identity=38.8185654008439, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI11875211, Length=234, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI40806170, Length=234, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI156564401, Length=234, Percent_Identity=38.4615384615385, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI31742536, Length=233, Percent_Identity=34.3347639484979, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI112789543, Length=233, Percent_Identity=34.3347639484979, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI310125282, Length=234, Percent_Identity=38.034188034188, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310125280, Length=231, Percent_Identity=38.0952380952381, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI64084766, Length=260, Percent_Identity=28.0769230769231, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI116292174, Length=285, Percent_Identity=29.1228070175439, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4757852, Length=160, Percent_Identity=31.25, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI119964730, Length=160, Percent_Identity=31.25, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789568, Length=598, Percent_Identity=52.0066889632107, Blast_Score=638, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=457, Percent_Identity=51.4223194748359, Blast_Score=447, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17554264, Length=443, Percent_Identity=48.3069977426637, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115534323, Length=455, Percent_Identity=46.3736263736264, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17563248, Length=253, Percent_Identity=45.8498023715415, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17554786, Length=254, Percent_Identity=45.6692913385827, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI25144278, Length=254, Percent_Identity=45.2755905511811, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=254, Percent_Identity=45.2755905511811, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17532375, Length=232, Percent_Identity=41.8103448275862, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17508701, Length=279, Percent_Identity=40.1433691756272, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17531535, Length=233, Percent_Identity=42.9184549356223, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17563250, Length=254, Percent_Identity=41.7322834645669, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=227, Percent_Identity=44.0528634361233, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71987372, Length=227, Percent_Identity=44.0528634361233, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=251, Percent_Identity=41.8326693227092, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508053, Length=255, Percent_Identity=41.5686274509804, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=39.4422310756972, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=282, Percent_Identity=37.2340425531915, Blast_Score=175, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI133931034, Length=248, Percent_Identity=40.7258064516129, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193206114, Length=248, Percent_Identity=40.7258064516129, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193206116, Length=248, Percent_Identity=40.7258064516129, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25153574, Length=265, Percent_Identity=36.2264150943396, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI193209502, Length=262, Percent_Identity=36.2595419847328, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=49.0909090909091, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=49.0909090909091, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI86561515, Length=232, Percent_Identity=37.5, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133901658, Length=263, Percent_Identity=37.6425855513308, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=262, Percent_Identity=37.0229007633588, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=251, Percent_Identity=34.6613545816733, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=234, Percent_Identity=40.1709401709402, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17508421, Length=263, Percent_Identity=36.8821292775665, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI32563584, Length=249, Percent_Identity=37.3493975903614, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17541224, Length=239, Percent_Identity=35.1464435146443, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=239, Percent_Identity=35.1464435146443, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=228, Percent_Identity=36.8421052631579, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323736, Length=494, Percent_Identity=47.5708502024291, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6320854, Length=466, Percent_Identity=48.7124463519313, Blast_Score=451, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325281, Length=451, Percent_Identity=45.6762749445676, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=42.911877394636, Blast_Score=218, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=42.9133858267717, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6320077, Length=242, Percent_Identity=43.801652892562, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=259, Percent_Identity=43.6293436293436, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6320197, Length=254, Percent_Identity=40.5511811023622, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=41.4634146341463, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=244, Percent_Identity=43.0327868852459, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324000, Length=286, Percent_Identity=36.7132867132867, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322651, Length=251, Percent_Identity=37.0517928286853, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6321709, Length=243, Percent_Identity=40.7407407407407, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323429, Length=252, Percent_Identity=38.0952380952381, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322994, Length=236, Percent_Identity=38.135593220339, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6325431, Length=262, Percent_Identity=34.7328244274809, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=247, Percent_Identity=36.8421052631579, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319554, Length=218, Percent_Identity=37.1559633027523, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=241, Percent_Identity=35.6846473029046, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=251, Percent_Identity=33.0677290836653, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=192, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665814, Length=493, Percent_Identity=48.2758620689655, Blast_Score=453, Evalue=1e-127,
Organism=Drosophila melanogaster, GI28574878, Length=493, Percent_Identity=48.2758620689655, Blast_Score=453, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24639391, Length=447, Percent_Identity=49.8881431767338, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24658770, Length=498, Percent_Identity=44.9799196787149, Blast_Score=424, Evalue=1e-118,
Organism=Drosophila melanogaster, GI17137738, Length=246, Percent_Identity=45.9349593495935, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI161076486, Length=241, Percent_Identity=43.5684647302905, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI17137560, Length=241, Percent_Identity=43.5684647302905, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI161076488, Length=241, Percent_Identity=43.5684647302905, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI19920408, Length=254, Percent_Identity=44.4881889763779, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI45554047, Length=170, Percent_Identity=58.8235294117647, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24651451, Length=254, Percent_Identity=43.7007874015748, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI17738151, Length=252, Percent_Identity=44.4444444444444, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24660075, Length=252, Percent_Identity=42.8571428571429, Blast_Score=205, Evalue=9e-53,
Organism=Drosophila melanogaster, GI281365776, Length=252, Percent_Identity=42.8571428571429, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI45552965, Length=252, Percent_Identity=42.8571428571429, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24652279, Length=203, Percent_Identity=45.320197044335, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24640100, Length=255, Percent_Identity=40.3921568627451, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24649446, Length=254, Percent_Identity=40.9448818897638, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI19921202, Length=261, Percent_Identity=38.6973180076628, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=38.0392156862745, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281361487, Length=262, Percent_Identity=38.1679389312977, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI18860063, Length=234, Percent_Identity=41.025641025641, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24656820, Length=287, Percent_Identity=37.9790940766551, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24656825, Length=271, Percent_Identity=38.7453874538745, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363136, Length=241, Percent_Identity=39.0041493775934, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI78707192, Length=241, Percent_Identity=39.0041493775934, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24644145, Length=263, Percent_Identity=37.2623574144487, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI281360136, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24644411, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360146, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360138, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360144, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360140, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360142, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21357333, Length=255, Percent_Identity=37.2549019607843, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21355121, Length=240, Percent_Identity=35.4166666666667, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI18859657, Length=233, Percent_Identity=39.4849785407725, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI20129529, Length=247, Percent_Identity=36.0323886639676, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571849, Length=229, Percent_Identity=40.174672489083, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571847, Length=229, Percent_Identity=40.174672489083, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24581396, Length=292, Percent_Identity=35.958904109589, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129423, Length=248, Percent_Identity=34.2741935483871, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI17864540, Length=265, Percent_Identity=35.4716981132075, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI28573010, Length=224, Percent_Identity=38.8392857142857, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24639486, Length=282, Percent_Identity=30.1418439716312, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 68051; Mature: 68051

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNNKIFRSMVLYLLIFIAIYAMVQLYSQATPQVTKIDYGELVRYISANQIKSITLSGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCEEEEEECCC
QVKGVFKNGTEFESSVPDITNFMSFVDPYILEGKLDFKYEPQVGPPWWVQMLPSLFLVGV
EEEHHHCCCCCHHHCCCHHHHHHHHHCCHHCCCEECEEECCCCCCHHHHHHHHHHHHHHH
LILFWYIFMQQAQGGGGSRVMSFGKSRARMVTDKDKRVTFNDVAGADEEKEELQEIVEFL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHHHHHHH
KYPKKFIELGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGAA
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCHH
RVRDLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGI
HHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCE
IVIAATNRPDILDPALLRPGRFDRHIVVNIPDIKGREEILKVHARNKPLAPDVSLQVIAR
EEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEE
RTPGFTGADLENVMNEAALLAARKGLKQITMAELEEAITRVVAGPEKRSRIMSEKDKKLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
AYHEAGHAVVAKLLPTTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
EEHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
GRAAEKLVLNDISTGAQNDIERATNIARKMVTEYGMSDRLGPMTFGTKSEEVFLGRDLGR
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCC
TRNYSEEVAAEIDREIRRIIEEAYKRAESLLQENIDKLHRVAKALMEKEKLNGEEFEKVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NGEEIEGVSFA
CCCCCCCCCCC
>Mature Secondary Structure
MKDNNKIFRSMVLYLLIFIAIYAMVQLYSQATPQVTKIDYGELVRYISANQIKSITLSGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCEEEEEECCC
QVKGVFKNGTEFESSVPDITNFMSFVDPYILEGKLDFKYEPQVGPPWWVQMLPSLFLVGV
EEEHHHCCCCCHHHCCCHHHHHHHHHCCHHCCCEECEEECCCCCCHHHHHHHHHHHHHHH
LILFWYIFMQQAQGGGGSRVMSFGKSRARMVTDKDKRVTFNDVAGADEEKEELQEIVEFL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHHHHHHH
KYPKKFIELGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGAA
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCHH
RVRDLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGI
HHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCE
IVIAATNRPDILDPALLRPGRFDRHIVVNIPDIKGREEILKVHARNKPLAPDVSLQVIAR
EEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEE
RTPGFTGADLENVMNEAALLAARKGLKQITMAELEEAITRVVAGPEKRSRIMSEKDKKLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
AYHEAGHAVVAKLLPTTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
EEHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
GRAAEKLVLNDISTGAQNDIERATNIARKMVTEYGMSDRLGPMTFGTKSEEVFLGRDLGR
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCC
TRNYSEEVAAEIDREIRRIIEEAYKRAESLLQENIDKLHRVAKALMEKEKLNGEEFEKVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NGEEIEGVSFA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA