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The map label for this gene is ArgK [C]

Identifier: 20808751

GI number: 20808751

Start: 2274546

End: 2275490

Strand: Reverse

Name: ArgK [C]

Synonym: TTE2387

Alternate gene names: 20808751

Gene position: 2275490-2274546 (Counterclockwise)

Preceding gene: 20808752

Following gene: 20808750

Centisome position: 84.61

GC content: 41.27

Gene sequence:

>945_bases
ATGATGGAATTAGAAAAGCTGCTTCTTAATAGAGACAAAAGAGCAATAGCAAGAGCCATAACCTACGCTGAAGACGACGA
AGAAAAAGCCAGGGAGATAATAAGAAAACTTTACAAAAGGTCCGGCAATGCCTATATAGTTGGCATTACCGGACCGCCAG
GGGTTGGCAAGAGCACTTTGACTGACAGATTGGTAAAGAATTTGGTGGAAGAGGGGAAAAAAATAGGAATAATAGCTGTT
GACCCTACGAGTCCTTTTACTGGCGGGTCTATACTTGGCGACAGGATAAGGATGCAGGATTTGACCACACATCCCAATGT
CTACATAAGGAGCATGGGGACAAGAGGACATCTCGGAGGGCTTTCAAAAGGAACCTATATGGCGGTGAGAATTTTAGATA
TAGCAGGGATGGACTACGTGTTTGTTGAGACTGTAGGAGTAGGCCAATCAGAGGTAGACATAATAAAAATAGCTGATACA
GTGGTGATGGTTTTAGCGCCCGGACTTGGAGATGATATACAGGCCATAAAGGCTGGAATAATGGAGATAGCAGATGTATT
CGTTGTAAACAAAAGCGACAGAGAAGGAGCTGATAAAACTGTATTAGAGCTTAACATGATGCTTGACTTAGATATGCCAA
AGGAGTGGAGACCTCCTGTTGTAAAAGCAGTAGCACAGGAGGGAAAGGGTATAGGTGAGGTGCTTGAAAAAATTCATTCT
CATAAAGAGTACCTCATCTCAAGCGGTCAGCTTGAAGAGAGGAGAAAAAACAGAATAAAAATGGAAATAACAGAAAGTGT
AAAAAATAAGCTTATGAAAGACGTGTTTGCAAAAATGGGAAACGAAGAATTTGACCAGAAAATTCAAAAAGTCATGGCTA
AAGAAATTGACCCTTATACAGTTGCAGAAGCTCTCTATAGGCAAATACTTGAGAGGAGGGAATGA

Upstream 100 bases:

>100_bases
TTTTGAAAGAGCACGGCATAGCAGAGATATTCACCCCTGGCACTCCCACTTCAGCAGTCATTGAATATATAAAAGCCAAT
GTTAAGAGGTTGGCAAAAAA

Downstream 100 bases:

>100_bases
TGTGATTAAAAAGGTAGACCATATAGGGATAGCAGTAAAGAGCATAGAAGAAGCGAGAAAGTTTTATGAAGAAGTGCTGG
GCTTGAAAGTGACAGGGATA

Product: periplasmic protein kinase ArgK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MMELEKLLLNRDKRAIARAITYAEDDEEKAREIIRKLYKRSGNAYIVGITGPPGVGKSTLTDRLVKNLVEEGKKIGIIAV
DPTSPFTGGSILGDRIRMQDLTTHPNVYIRSMGTRGHLGGLSKGTYMAVRILDIAGMDYVFVETVGVGQSEVDIIKIADT
VVMVLAPGLGDDIQAIKAGIMEIADVFVVNKSDREGADKTVLELNMMLDLDMPKEWRPPVVKAVAQEGKGIGEVLEKIHS
HKEYLISSGQLEERRKNRIKMEITESVKNKLMKDVFAKMGNEEFDQKIQKVMAKEIDPYTVAEALYRQILERRE

Sequences:

>Translated_314_residues
MMELEKLLLNRDKRAIARAITYAEDDEEKAREIIRKLYKRSGNAYIVGITGPPGVGKSTLTDRLVKNLVEEGKKIGIIAV
DPTSPFTGGSILGDRIRMQDLTTHPNVYIRSMGTRGHLGGLSKGTYMAVRILDIAGMDYVFVETVGVGQSEVDIIKIADT
VVMVLAPGLGDDIQAIKAGIMEIADVFVVNKSDREGADKTVLELNMMLDLDMPKEWRPPVVKAVAQEGKGIGEVLEKIHS
HKEYLISSGQLEERRKNRIKMEITESVKNKLMKDVFAKMGNEEFDQKIQKVMAKEIDPYTVAEALYRQILERRE
>Mature_314_residues
MMELEKLLLNRDKRAIARAITYAEDDEEKAREIIRKLYKRSGNAYIVGITGPPGVGKSTLTDRLVKNLVEEGKKIGIIAV
DPTSPFTGGSILGDRIRMQDLTTHPNVYIRSMGTRGHLGGLSKGTYMAVRILDIAGMDYVFVETVGVGQSEVDIIKIADT
VVMVLAPGLGDDIQAIKAGIMEIADVFVVNKSDREGADKTVLELNMMLDLDMPKEWRPPVVKAVAQEGKGIGEVLEKIHS
HKEYLISSGQLEERRKNRIKMEITESVKNKLMKDVFAKMGNEEFDQKIQKVMAKEIDPYTVAEALYRQILERRE

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=325, Percent_Identity=33.2307692307692, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI1789285, Length=290, Percent_Identity=35.1724137931034, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71994271, Length=333, Percent_Identity=34.8348348348348, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI71994275, Length=293, Percent_Identity=36.518771331058, Blast_Score=180, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35075; Mature: 35075

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELEKLLLNRDKRAIARAITYAEDDEEKAREIIRKLYKRSGNAYIVGITGPPGVGKSTL
CCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
TDRLVKNLVEEGKKIGIIAVDPTSPFTGGSILGDRIRMQDLTTHPNVYIRSMGTRGHLGG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LSKGTYMAVRILDIAGMDYVFVETVGVGQSEVDIIKIADTVVMVLAPGLGDDIQAIKAGI
CCCCCEEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MEIADVFVVNKSDREGADKTVLELNMMLDLDMPKEWRPPVVKAVAQEGKGIGEVLEKIHS
HHHHHHHEECCCCCCCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
HKEYLISSGQLEERRKNRIKMEITESVKNKLMKDVFAKMGNEEFDQKIQKVMAKEIDPYT
HHHHHHCCCCHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
VAEALYRQILERRE
HHHHHHHHHHHHCC
>Mature Secondary Structure
MMELEKLLLNRDKRAIARAITYAEDDEEKAREIIRKLYKRSGNAYIVGITGPPGVGKSTL
CCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
TDRLVKNLVEEGKKIGIIAVDPTSPFTGGSILGDRIRMQDLTTHPNVYIRSMGTRGHLGG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LSKGTYMAVRILDIAGMDYVFVETVGVGQSEVDIIKIADTVVMVLAPGLGDDIQAIKAGI
CCCCCEEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MEIADVFVVNKSDREGADKTVLELNMMLDLDMPKEWRPPVVKAVAQEGKGIGEVLEKIHS
HHHHHHHEECCCCCCCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
HKEYLISSGQLEERRKNRIKMEITESVKNKLMKDVFAKMGNEEFDQKIQKVMAKEIDPYT
HHHHHHCCCCHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
VAEALYRQILERRE
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]