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The map label for this gene is AccB2 [H]

Identifier: 20808747

GI number: 20808747

Start: 2271862

End: 2272230

Strand: Reverse

Name: AccB2 [H]

Synonym: TTE2383

Alternate gene names: 20808747

Gene position: 2272230-2271862 (Counterclockwise)

Preceding gene: 20808748

Following gene: 20808746

Centisome position: 84.49

GC content: 39.84

Gene sequence:

>369_bases
ATGAGGAAATTCAAAGTTACAGTAAATGGCAAGACTTATGAAGTAGAGGTAGAAGAGATGAAGGCAGAAGAAGAGAAAGA
GCTAAGCAAAAAAGAGGAAATAGTGGAGGTTAAAGAGGTTCCTAAACAGGAGGAGAAAGTTTCTACAGGAAAAGGCTCTA
AAGTAGTTTCTGCTCCTATGCCTGGTACAATTCTAGACGTCAGAGTAAAAGAGGGAGATAGAGTAAAAAGAGGGGATGTG
CTACTGATTTTAGAAGCCATGAAGATGGAAAACGAGATAATGGCTCCTGAAGATGGGATTGTAGCTAGTGTGAATGTGTC
AAAAGGGGCTTCTGTAAATACAGGAGATGTCCTTGTCACTATGGAATAA

Upstream 100 bases:

>100_bases
ACATAAGGTCTATACGGGAGACCTCAGAGGCAGTTCCTCTGTGGTCTGTAGTTGGAAGAGTAGAGCAGATGCAAGCACGG
TTTTTAAGGAGGTATTGTTG

Downstream 100 bases:

>100_bases
AAACTTCTTGATAAATTAGCATTTTTTATGGTAAAATGAAAACTGCGGGTATCGGTTTCGAACCTGACAGCTTTTAAAAA
TTTAATATTGTCATGCGTTC

Product: biotin carboxyl carrier protein

Products: NA

Alternate protein names: Biotin carrier [H]

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MRKFKVTVNGKTYEVEVEEMKAEEEKELSKKEEIVEVKEVPKQEEKVSTGKGSKVVSAPMPGTILDVRVKEGDRVKRGDV
LLILEAMKMENEIMAPEDGIVASVNVSKGASVNTGDVLVTME

Sequences:

>Translated_122_residues
MRKFKVTVNGKTYEVEVEEMKAEEEKELSKKEEIVEVKEVPKQEEKVSTGKGSKVVSAPMPGTILDVRVKEGDRVKRGDV
LLILEAMKMENEIMAPEDGIVASVNVSKGASVNTGDVLVTME
>Mature_122_residues
MRKFKVTVNGKTYEVEVEEMKAEEEKELSKKEEIVEVKEVPKQEEKVSTGKGSKVVSAPMPGTILDVRVKEGDRVKRGDV
LLILEAMKMENEIMAPEDGIVASVNVSKGASVNTGDVLVTME

Specific function: Biotin carrier subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD) [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=120, Percent_Identity=39.1666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI65506442, Length=70, Percent_Identity=44.2857142857143, Blast_Score=62, Evalue=8e-11,
Organism=Homo sapiens, GI189095269, Length=70, Percent_Identity=44.2857142857143, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17567343, Length=91, Percent_Identity=45.0549450549451, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652212, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652210, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652214, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921944, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652216, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281363050, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652224, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652222, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652220, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652218, Length=67, Percent_Identity=41.7910447761194, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: =4.1.1.70 [H]

Molecular weight: Translated: 13437; Mature: 13437

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFKVTVNGKTYEVEVEEMKAEEEKELSKKEEIVEVKEVPKQEEKVSTGKGSKVVSAPM
CCEEEEEECCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEECCC
PGTILDVRVKEGDRVKRGDVLLILEAMKMENEIMAPEDGIVASVNVSKGASVNTGDVLVT
CCEEEEEEECCCCCEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEE
ME
EC
>Mature Secondary Structure
MRKFKVTVNGKTYEVEVEEMKAEEEKELSKKEEIVEVKEVPKQEEKVSTGKGSKVVSAPM
CCEEEEEECCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEECCC
PGTILDVRVKEGDRVKRGDVLLILEAMKMENEIMAPEDGIVASVNVSKGASVNTGDVLVT
CCEEEEEEECCCCCEECCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEE
ME
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10027965 [H]