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The map label for this gene is Thy1

Identifier: 20808601

GI number: 20808601

Start: 2130717

End: 2132237

Strand: Reverse

Name: Thy1

Synonym: TTE2225

Alternate gene names: NA

Gene position: 2132237-2130717 (Counterclockwise)

Preceding gene: 20808603

Following gene: 20808600

Centisome position: 79.28

GC content: 39.64

Gene sequence:

>1521_bases
ATGCAGATGAGGAAGCTGACTCCAGAGGAAGAGAAGCTCCTTCAAAATTTTGTTACCGATGTCTACGGCCCAGTGTACTT
CATACATTCTCTTCCAGAATTTATAATCCCACCTATAAATTCAAAGGTGAGCAGAAAAGATACGAGCTGGAGGCTTAACA
TTCTTGAATCTCTCACAGATGGGGATTTGGATATAACGGAGTACCTGCCTAAACATAGCATTCCCATGGAAAGAGCTATA
GAGAAAGCTAGAGAATTTCATGAAAAGTGGGTTGAAAAGTTTGGGCATTCATCAATTGCAGAGCAGCACTTGATGCACCT
TTGTGTGGAAGATGTATCCAGACTTTTGTCCGGCGACATTGAACTTATGAACAGAAGACCTGCATTTATAGAATGGAGTC
AGAGGTATCAGAAGCCAACAAGAGAGAAAGTAGTTATCCCGCCCGAATTAGAGAAAGAACCTGTCTTAAAGGAAAAGTTT
TTAAAAGTTTGGAATGCAACTTACGATGCGTATGAAAAGCTGGTAAAGGTTTTGACAGAATATTTGAGGAGAGCAGAGGA
GAAAAAAGAAGGTGAAACTGAAGAAAAATTTTTAAATAGGATAGAAAAGATCGCTTTTGAAGACGCGCGCTATGCATTAA
TTCTTGCAACTAGGACGAGCTTCGCAGTTGCCTTAAACGCCTTAGACTTGCAGGACATTGTGAGAAAGTTGTTTGCCCAT
CCTACAGAAGAAGCAAAAGTGCTTGCAAAAAGGATAGTAGAACAAGGGGAGAAGATTGCGCCGAGCACCTTAAGACATCT
CACTCCTACTCCTTATCAGATGAAGGTGAGAGAAAGATTAAAGGATATATCAAAAAAAATCCTGGGAGATAAGAGGGCTA
TTTCTTCTGATGATGTAGTTCTTTTAGATTATACGGGGAAGGGTACGGATTTTTCTCCAGTTGATACAGTTGTCGCTCAT
ATCTTATTTACTTATTCTGGTAAAGAATTTGTGGAAGTAAAAGAAAAAGTAAAAGCAATGAAGGAAGAAGAAAAGGAGAA
AGTTATAAAAACTGCGGTAGAAGAGATTGGAGAGTTTGACCATCTGATAGATGCTTTTAAATCGGTAAGGTTTAAATTCC
AGCTTAAAATAAGCGAAGCTAACTGGCATCAACTCTTGCGTCACCGGACCATAATATTTGACTGGACAGAGCCGACTGTA
GAAAATGGATTTGTCATTCCTCCAAATGTAGTAAAAGCTGGCGCTGAAGATATTTTAATTGGGGCTTTAAAAACCTCGGA
AGAGTTATTCTATGAGCTTAAAGAGAAAATGCCTGAAGTGAGCCCTTACGTGGTCACAAATGCTCATAAGAGATTGGTTG
TGATGAATGCAGATTTGTGGGCTTTTGACCACTTTGCGAATTTGAGATGTACAAAGGAAGCACAGTGGGACATAAGGGAA
ACGTCTTTTAAAATGCTTGGACTCATAAGAGAAGTAGCGCCTCAACTGGCCTTTTTTATGGCGAGAAGGAAAAGAGCTTA
A

Upstream 100 bases:

>100_bases
AACAGCTATCAGCAGATAGCTGTTTTTTTATATATTTTTGTGGTACAATTATATAAAGTATGGTTCGCTGTTTTTACAAT
TTTTGAAAGGAGTTTTTACC

Downstream 100 bases:

>100_bases
AAGATGGAGAGGAGATTATGAAAACGAGTTTTAAGGAAATAAGTTTGCCAAAACTTAATAACCTTACTCCTTCACTGGAG
TCCACTGCTTTGAAGTTGAT

Product: alternative thymidylate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MQMRKLTPEEEKLLQNFVTDVYGPVYFIHSLPEFIIPPINSKVSRKDTSWRLNILESLTDGDLDITEYLPKHSIPMERAI
EKAREFHEKWVEKFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTREKVVIPPELEKEPVLKEKF
LKVWNATYDAYEKLVKVLTEYLRRAEEKKEGETEEKFLNRIEKIAFEDARYALILATRTSFAVALNALDLQDIVRKLFAH
PTEEAKVLAKRIVEQGEKIAPSTLRHLTPTPYQMKVRERLKDISKKILGDKRAISSDDVVLLDYTGKGTDFSPVDTVVAH
ILFTYSGKEFVEVKEKVKAMKEEEKEKVIKTAVEEIGEFDHLIDAFKSVRFKFQLKISEANWHQLLRHRTIIFDWTEPTV
ENGFVIPPNVVKAGAEDILIGALKTSEELFYELKEKMPEVSPYVVTNAHKRLVVMNADLWAFDHFANLRCTKEAQWDIRE
TSFKMLGLIREVAPQLAFFMARRKRA

Sequences:

>Translated_506_residues
MQMRKLTPEEEKLLQNFVTDVYGPVYFIHSLPEFIIPPINSKVSRKDTSWRLNILESLTDGDLDITEYLPKHSIPMERAI
EKAREFHEKWVEKFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTREKVVIPPELEKEPVLKEKF
LKVWNATYDAYEKLVKVLTEYLRRAEEKKEGETEEKFLNRIEKIAFEDARYALILATRTSFAVALNALDLQDIVRKLFAH
PTEEAKVLAKRIVEQGEKIAPSTLRHLTPTPYQMKVRERLKDISKKILGDKRAISSDDVVLLDYTGKGTDFSPVDTVVAH
ILFTYSGKEFVEVKEKVKAMKEEEKEKVIKTAVEEIGEFDHLIDAFKSVRFKFQLKISEANWHQLLRHRTIIFDWTEPTV
ENGFVIPPNVVKAGAEDILIGALKTSEELFYELKEKMPEVSPYVVTNAHKRLVVMNADLWAFDHFANLRCTKEAQWDIRE
TSFKMLGLIREVAPQLAFFMARRKRA
>Mature_506_residues
MQMRKLTPEEEKLLQNFVTDVYGPVYFIHSLPEFIIPPINSKVSRKDTSWRLNILESLTDGDLDITEYLPKHSIPMERAI
EKAREFHEKWVEKFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTREKVVIPPELEKEPVLKEKF
LKVWNATYDAYEKLVKVLTEYLRRAEEKKEGETEEKFLNRIEKIAFEDARYALILATRTSFAVALNALDLQDIVRKLFAH
PTEEAKVLAKRIVEQGEKIAPSTLRHLTPTPYQMKVRERLKDISKKILGDKRAISSDDVVLLDYTGKGTDFSPVDTVVAH
ILFTYSGKEFVEVKEKVKAMKEEEKEKVIKTAVEEIGEFDHLIDAFKSVRFKFQLKISEANWHQLLRHRTIIFDWTEPTV
ENGFVIPPNVVKAGAEDILIGALKTSEELFYELKEKMPEVSPYVVTNAHKRLVVMNADLWAFDHFANLRCTKEAQWDIRE
TSFKMLGLIREVAPQLAFFMARRKRA

Specific function: Unknown

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 thyX (flavin-dependent thymidylate synthase) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: NA

Molecular weight: Translated: 58932; Mature: 58932

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMRKLTPEEEKLLQNFVTDVYGPVYFIHSLPEFIIPPINSKVSRKDTSWRLNILESLTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
GDLDITEYLPKHSIPMERAIEKAREFHEKWVEKFGHSSIAEQHLMHLCVEDVSRLLSGDI
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ELMNRRPAFIEWSQRYQKPTREKVVIPPELEKEPVLKEKFLKVWNATYDAYEKLVKVLTE
HHHCCCCCCEEHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRRAEEKKEGETEEKFLNRIEKIAFEDARYALILATRTSFAVALNALDLQDIVRKLFAH
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCC
PTEEAKVLAKRIVEQGEKIAPSTLRHLTPTPYQMKVRERLKDISKKILGDKRAISSDDVV
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LLDYTGKGTDFSPVDTVVAHILFTYSGKEFVEVKEKVKAMKEEEKEKVIKTAVEEIGEFD
EEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIDAFKSVRFKFQLKISEANWHQLLRHRTIIFDWTEPTVENGFVIPPNVVKAGAEDILI
HHHHHHHHCEEEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCEECCCHHHHCCCHHHEE
GALKTSEELFYELKEKMPEVSPYVVTNAHKRLVVMNADLWAFDHFANLRCTKEAQWDIRE
EHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCHHHHHHHCCCEECCCCCCCHHH
TSFKMLGLIREVAPQLAFFMARRKRA
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQMRKLTPEEEKLLQNFVTDVYGPVYFIHSLPEFIIPPINSKVSRKDTSWRLNILESLTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
GDLDITEYLPKHSIPMERAIEKAREFHEKWVEKFGHSSIAEQHLMHLCVEDVSRLLSGDI
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ELMNRRPAFIEWSQRYQKPTREKVVIPPELEKEPVLKEKFLKVWNATYDAYEKLVKVLTE
HHHCCCCCCEEHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRRAEEKKEGETEEKFLNRIEKIAFEDARYALILATRTSFAVALNALDLQDIVRKLFAH
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCC
PTEEAKVLAKRIVEQGEKIAPSTLRHLTPTPYQMKVRERLKDISKKILGDKRAISSDDVV
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LLDYTGKGTDFSPVDTVVAHILFTYSGKEFVEVKEKVKAMKEEEKEKVIKTAVEEIGEFD
EEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIDAFKSVRFKFQLKISEANWHQLLRHRTIIFDWTEPTVENGFVIPPNVVKAGAEDILI
HHHHHHHHCEEEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCEECCCHHHHCCCHHHEE
GALKTSEELFYELKEKMPEVSPYVVTNAHKRLVVMNADLWAFDHFANLRCTKEAQWDIRE
EHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCHHHHHHHCCCEECCCCCCCHHH
TSFKMLGLIREVAPQLAFFMARRKRA
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]