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The map label for this gene is RecD2 [H]

Identifier: 20808503

GI number: 20808503

Start: 2030600

End: 2032771

Strand: Reverse

Name: RecD2 [H]

Synonym: TTE2109

Alternate gene names: 20808503

Gene position: 2032771-2030600 (Counterclockwise)

Preceding gene: 20808504

Following gene: 20808502

Centisome position: 75.58

GC content: 39.04

Gene sequence:

>2172_bases
ATGATAGAAAACCTGCAGGAAATCAAAAACTGCACAATTGAAAAAATTATTTTCACATCAAACGACGGTTATACAGTTGC
AGCTGTCCGAACAGAAGACAATAACTTTGTTGCAACCTTTCAGGGCAGTTACAAACAGGGACAGAAGCTGGATTTGATAG
GAGAATGGTACGTCCATTCGAAATACGGCAGACAGTTCAGAGTTGTATTCGCAGAAATATCAAAAGACGCAGATGAGGAC
GATATAGAAATTTTTCTCCAAAGCATAAAAGGCATAGGCCCGGTAAGGGCAAGGAAAATAGTCGCAGCATTTAAAAAACA
TACCATACAGGTTATTGAAAAAAACCCCGAAAAGCTCAGAGAAATTGGGATACCACAGAAGGTAGTTGATTCAGTAAATG
CTGAAATTACGCAGAACAAAGAGTTCAACGAAATAAAGCTTGAGCTTCTGCTTTTAGGATTTTCGCTGAACATGATAAAA
AAGCTTTATGACCGCTACGGCAGTAATACACTCCTGCAGGTAAAAGCGAATCCCTACAAAATTGCAGAAGAAGTTGACGG
AATAGGCTTTATTAAAGCCGATGAAATAGCCAGAAAATTTGGCATAGAGCAGGATAATGCCTACAGGATTCAGTCAGGCT
TAAAATATACGCTGTACCTTGCCGAAACAGAAGGACACTTATACCTGCCGATTACAACACTGTGCAAAGCAGCATCGGAG
AAGATTTTAAAAGTAGGGTACACAAAAGTTTTAGATCAGGCTCTGTATTTAACAGCTGCACAGGAGCTTTATGACGATGA
AGGGAAAGTGTACCTGCCTAAAAATTTTTACAACGAAAAGTACATTGCTGAGAAAATTGCTAAGATGCTCAATGAAAAGC
CCTGGAGAATAAACAACATTGATGAGCTTATCAAAGAAGCAGAGGCTGCAAAAAACATCAGATACAGTCCAAAACAGAAA
GAAGCCATAAAAAAGGCGGTTGAAAACAACATATCCATCATAACTGGAGGGCCGGGCACAGGAAAAACGACGATTGTCAG
CGCTCTTCTATATATTTTCCAAAAACAAGATAAGCTTGTGGCTTTAGCATCTCCAACAGGCAAAGCAGCAAAAAGGCTTG
AAGAAGTAACAATCTACCCGGCAAAAACGATCCACAGACTGCTGGAGGCAAGGTTTGATAAAGAATTTAGGAGTGTAAGA
TTTTTTAGAAACGAAAATAATCCTCTTGATGAGGATGTTGTTATTATTGATGAATTCTCAATGGTTGACAATGAACTTGC
TGCAAGTTTATTTAAAGCCTTGAGGAAAGATACAAAGCTTGTCATAATAGGAGACATGGATCAGCTTCCATCAGTAGGCG
CAGGAAACGTCTTAAGAGACTTAATTGAGTCGGGTATAATACCTGTAACAAAACTTGACGTTATTTTCAGGCAGGGAGAA
ACGTCAGGGATAATCCTCAACTCGAAACTCATAAGAGAAGGGAAAATGGTGCGATTTAATAACAAAGATTTTATCTTTCA
TGAACTTGTAAAGCCTGAGCAGGTTGTAGATGAGTTTATAAAAGAACTTGAAAAAGGCAAAACACTTGATGATGTGCAGA
TTTTAACACCAATGAAAAAGACAGACATAGGGACGCTGGAGTTGAACAGGCTGATACAGGAACGAATAAATCCACCACAT
CCCCAGAAAGAGGAAATAGCATACGGCAGCAAAATATTCAGAGTTGGAGATAAAGTCATGCAGACTCAAAACAACTACGA
AAAAGAAATCTTCAATGGCGACACGGGCTATGTAAAAAGAGCTTACAGAGACGAAGAAGGTCTAAGGCATGTTGTGATAG
ATTTTGATGGGCGAATAGTCGATCTGGTAGAGGAAGAGTTAAAAGAAATAATTCCTGCCTATGCAATCACAATCCATAAG
TCGCAGGGCAGTGAGTACGATACTGTAATCGTGGTACTTGCAATGAACCACTACATCATGCTTAAAAGAAACCTTCTGTA
CACTGCTGTCACAAGAGCTAAAAACGTTGTTAAAATCTTTGGAGACATGCAGGCTATAAAAATAGCTATAAACACAATTG
ACAGCTCAAAGAGGTATACGGCTCTAAAGGAGAGATTGAAAAACGTGAAGGAGTATGCTGAAAGGGGAATTTTATATGCT
CTGGAGATATAA

Upstream 100 bases:

>100_bases
AAGATAAACATTGCTCTCAGTTTATTTGATAGAGAGATGGGGATAGATTTTTCACCTGAACAGATCATGAAAATACAATA
ACTGCAAGGAAGTGGTTAAC

Downstream 100 bases:

>100_bases
TCCAAATACAAAAATTGAACTGCGGAGGAAGTATCCTGTAACTCCCAGCGACTTCCCCCTTTCTGACATTGTAAAAACTA
TTTTTGAAAGCAAAAGCATT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MIENLQEIKNCTIEKIIFTSNDGYTVAAVRTEDNNFVATFQGSYKQGQKLDLIGEWYVHSKYGRQFRVVFAEISKDADED
DIEIFLQSIKGIGPVRARKIVAAFKKHTIQVIEKNPEKLREIGIPQKVVDSVNAEITQNKEFNEIKLELLLLGFSLNMIK
KLYDRYGSNTLLQVKANPYKIAEEVDGIGFIKADEIARKFGIEQDNAYRIQSGLKYTLYLAETEGHLYLPITTLCKAASE
KILKVGYTKVLDQALYLTAAQELYDDEGKVYLPKNFYNEKYIAEKIAKMLNEKPWRINNIDELIKEAEAAKNIRYSPKQK
EAIKKAVENNISIITGGPGTGKTTIVSALLYIFQKQDKLVALASPTGKAAKRLEEVTIYPAKTIHRLLEARFDKEFRSVR
FFRNENNPLDEDVVIIDEFSMVDNELAASLFKALRKDTKLVIIGDMDQLPSVGAGNVLRDLIESGIIPVTKLDVIFRQGE
TSGIILNSKLIREGKMVRFNNKDFIFHELVKPEQVVDEFIKELEKGKTLDDVQILTPMKKTDIGTLELNRLIQERINPPH
PQKEEIAYGSKIFRVGDKVMQTQNNYEKEIFNGDTGYVKRAYRDEEGLRHVVIDFDGRIVDLVEEELKEIIPAYAITIHK
SQGSEYDTVIVVLAMNHYIMLKRNLLYTAVTRAKNVVKIFGDMQAIKIAINTIDSSKRYTALKERLKNVKEYAERGILYA
LEI

Sequences:

>Translated_723_residues
MIENLQEIKNCTIEKIIFTSNDGYTVAAVRTEDNNFVATFQGSYKQGQKLDLIGEWYVHSKYGRQFRVVFAEISKDADED
DIEIFLQSIKGIGPVRARKIVAAFKKHTIQVIEKNPEKLREIGIPQKVVDSVNAEITQNKEFNEIKLELLLLGFSLNMIK
KLYDRYGSNTLLQVKANPYKIAEEVDGIGFIKADEIARKFGIEQDNAYRIQSGLKYTLYLAETEGHLYLPITTLCKAASE
KILKVGYTKVLDQALYLTAAQELYDDEGKVYLPKNFYNEKYIAEKIAKMLNEKPWRINNIDELIKEAEAAKNIRYSPKQK
EAIKKAVENNISIITGGPGTGKTTIVSALLYIFQKQDKLVALASPTGKAAKRLEEVTIYPAKTIHRLLEARFDKEFRSVR
FFRNENNPLDEDVVIIDEFSMVDNELAASLFKALRKDTKLVIIGDMDQLPSVGAGNVLRDLIESGIIPVTKLDVIFRQGE
TSGIILNSKLIREGKMVRFNNKDFIFHELVKPEQVVDEFIKELEKGKTLDDVQILTPMKKTDIGTLELNRLIQERINPPH
PQKEEIAYGSKIFRVGDKVMQTQNNYEKEIFNGDTGYVKRAYRDEEGLRHVVIDFDGRIVDLVEEELKEIIPAYAITIHK
SQGSEYDTVIVVLAMNHYIMLKRNLLYTAVTRAKNVVKIFGDMQAIKIAINTIDSSKRYTALKERLKNVKEYAERGILYA
LEI
>Mature_723_residues
MIENLQEIKNCTIEKIIFTSNDGYTVAAVRTEDNNFVATFQGSYKQGQKLDLIGEWYVHSKYGRQFRVVFAEISKDADED
DIEIFLQSIKGIGPVRARKIVAAFKKHTIQVIEKNPEKLREIGIPQKVVDSVNAEITQNKEFNEIKLELLLLGFSLNMIK
KLYDRYGSNTLLQVKANPYKIAEEVDGIGFIKADEIARKFGIEQDNAYRIQSGLKYTLYLAETEGHLYLPITTLCKAASE
KILKVGYTKVLDQALYLTAAQELYDDEGKVYLPKNFYNEKYIAEKIAKMLNEKPWRINNIDELIKEAEAAKNIRYSPKQK
EAIKKAVENNISIITGGPGTGKTTIVSALLYIFQKQDKLVALASPTGKAAKRLEEVTIYPAKTIHRLLEARFDKEFRSVR
FFRNENNPLDEDVVIIDEFSMVDNELAASLFKALRKDTKLVIIGDMDQLPSVGAGNVLRDLIESGIIPVTKLDVIFRQGE
TSGIILNSKLIREGKMVRFNNKDFIFHELVKPEQVVDEFIKELEKGKTLDDVQILTPMKKTDIGTLELNRLIQERINPPH
PQKEEIAYGSKIFRVGDKVMQTQNNYEKEIFNGDTGYVKRAYRDEEGLRHVVIDFDGRIVDLVEEELKEIIPAYAITIHK
SQGSEYDTVIVVLAMNHYIMLKRNLLYTAVTRAKNVVKIFGDMQAIKIAINTIDSSKRYTALKERLKNVKEYAERGILYA
LEI

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=568, Percent_Identity=29.0492957746479, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 82524; Mature: 82524

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENLQEIKNCTIEKIIFTSNDGYTVAAVRTEDNNFVATFQGSYKQGQKLDLIGEWYVHS
CCCCHHHHHCCCEEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEHEEEEC
KYGRQFRVVFAEISKDADEDDIEIFLQSIKGIGPVRARKIVAAFKKHTIQVIEKNPEKLR
CCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EIGIPQKVVDSVNAEITQNKEFNEIKLELLLLGFSLNMIKKLYDRYGSNTLLQVKANPYK
HCCCCHHHHHHCCCCCCCCCCCCHHEEEHHEEHHHHHHHHHHHHHHCCCEEEEEECCCHH
IAEEVDGIGFIKADEIARKFGIEQDNAYRIQSGLKYTLYLAETEGHLYLPITTLCKAASE
HHHHCCCCCEEEHHHHHHHHCCCCCCCEEECCCCEEEEEEEECCCEEEEEHHHHHHHHHH
KILKVGYTKVLDQALYLTAAQELYDDEGKVYLPKNFYNEKYIAEKIAKMLNEKPWRINNI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCH
DELIKEAEAAKNIRYSPKQKEAIKKAVENNISIITGGPGTGKTTIVSALLYIFQKQDKLV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEE
ALASPTGKAAKRLEEVTIYPAKTIHRLLEARFDKEFRSVRFFRNENNPLDEDVVIIDEFS
EEECCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHH
MVDNELAASLFKALRKDTKLVIIGDMDQLPSVGAGNVLRDLIESGIIPVTKLDVIFRQGE
HHHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCC
TSGIILNSKLIREGKMVRFNNKDFIFHELVKPEQVVDEFIKELEKGKTLDDVQILTPMKK
CCEEEEEHHHHCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCC
TDIGTLELNRLIQERINPPHPQKEEIAYGSKIFRVGDKVMQTQNNYEKEIFNGDTGYVKR
CCCCHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
AYRDEEGLRHVVIDFDGRIVDLVEEELKEIIPAYAITIHKSQGSEYDTVIVVLAMNHYIM
HHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCEEE
LKRNLLYTAVTRAKNVVKIFGDMQAIKIAINTIDSSKRYTALKERLKNVKEYAERGILYA
EEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LEI
EEC
>Mature Secondary Structure
MIENLQEIKNCTIEKIIFTSNDGYTVAAVRTEDNNFVATFQGSYKQGQKLDLIGEWYVHS
CCCCHHHHHCCCEEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEHEEEEC
KYGRQFRVVFAEISKDADEDDIEIFLQSIKGIGPVRARKIVAAFKKHTIQVIEKNPEKLR
CCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EIGIPQKVVDSVNAEITQNKEFNEIKLELLLLGFSLNMIKKLYDRYGSNTLLQVKANPYK
HCCCCHHHHHHCCCCCCCCCCCCHHEEEHHEEHHHHHHHHHHHHHHCCCEEEEEECCCHH
IAEEVDGIGFIKADEIARKFGIEQDNAYRIQSGLKYTLYLAETEGHLYLPITTLCKAASE
HHHHCCCCCEEEHHHHHHHHCCCCCCCEEECCCCEEEEEEEECCCEEEEEHHHHHHHHHH
KILKVGYTKVLDQALYLTAAQELYDDEGKVYLPKNFYNEKYIAEKIAKMLNEKPWRINNI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCH
DELIKEAEAAKNIRYSPKQKEAIKKAVENNISIITGGPGTGKTTIVSALLYIFQKQDKLV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEE
ALASPTGKAAKRLEEVTIYPAKTIHRLLEARFDKEFRSVRFFRNENNPLDEDVVIIDEFS
EEECCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHH
MVDNELAASLFKALRKDTKLVIIGDMDQLPSVGAGNVLRDLIESGIIPVTKLDVIFRQGE
HHHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCC
TSGIILNSKLIREGKMVRFNNKDFIFHELVKPEQVVDEFIKELEKGKTLDDVQILTPMKK
CCEEEEEHHHHCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCC
TDIGTLELNRLIQERINPPHPQKEEIAYGSKIFRVGDKVMQTQNNYEKEIFNGDTGYVKR
CCCCHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHH
AYRDEEGLRHVVIDFDGRIVDLVEEELKEIIPAYAITIHKSQGSEYDTVIVVLAMNHYIM
HHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCEEE
LKRNLLYTAVTRAKNVVKIFGDMQAIKIAINTIDSSKRYTALKERLKNVKEYAERGILYA
EEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEE
LEI
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]