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The map label for this gene is SbcC2 [H]

Identifier: 20808433

GI number: 20808433

Start: 1975037

End: 1976686

Strand: Reverse

Name: SbcC2 [H]

Synonym: TTE2031

Alternate gene names: 20808433

Gene position: 1976686-1975037 (Counterclockwise)

Preceding gene: 20808434

Following gene: 20808432

Centisome position: 73.5

GC content: 34.06

Gene sequence:

>1650_bases
ATGATAATAAAATCGATAACCTTAAAAAACTTCAAGAGTCATAAAAATACAATTATTAATTTCAATGATAAAAACACCGT
AATCTATGGAGACAACGGAACTGGGAAAACTTCAATAGGAGAAGCAATAGCATGGTGCCTGACAGGGGCAAACCTGTTTG
GTACAGAAAATGTAACAAACAAATTAGTAACTATAGGGAAAAATGAAATGTCCGTAACCTTAGTTATAGAAAAAGATGGA
AAAGAATACGAAATAACCCGTTCAAAAAAGAAGAACGAAATAGAAATAACCATAAACGGTGTTAAGTCTACACAAATTGA
TCTGTATACTCAGTTCGTACAGGACAAGGACATATTCTTCACTGTATTCAACCCTCTATACTTTACAACTCTTGCTCCAA
GAGATGCCAAGGCCATTCTCTACAAAGTTTTGCCGGAGGTTTCCAACGAAGAAGTTTTCGAAAAACTTTCTCCAGAAGTA
GCAGAAACTTTAAAGAAAAACGGATTTAATAATGCAAACACCTTCATTGAAAAGCAGCGGGAAATTCTAAAAGACTGGGA
AGACGGGCTTTTAAAATCTGAAGGGAATATAGAGATATTGAGACAGATAATAAATGCAAAGATTCCCGAAATGAAAAGCT
TTGATGAAACACAGTTAAAAGAGCTGGAAAAGAAACTAATGGAGTTCCAGAAAAATCAAAACATAGAAATAGAAAAGGAG
CTTGCAATACTGAAAGAACAATACAAAAACCCACCGATAGAGAAACCTCAGTTAAAAGACACAAGCATCCTGCAGAAAAC
CAGAGAAGAACTGCTGCAGGAATACAAACAAATTCAAGAGCAAATCAAAAACCTTAAACCACAGTACATCACCTGTAATA
AATGTGGCAATAAAATAGATGTTACTGCAAAAGAAAAGCAGCTTTTACTGGCAAAGCTGCAGGAGATAAAAGAAAAAGGC
ACAAAAACTGCTGCAGAGTTGAAGGCTGTTATCGAAGAAAACGAAAAGGCAGAAAAAGAGTTTAAAGAAAAAGTAAACAA
ATACAGAAAAGCCCTTGAGATAAAAATCAAGAGACTAGAAAATGCACTAAATACAAATGCAAACAAAGAACAAATACAGC
AAATAATGCAGCAAATAGAAAGGCTCAGATTTGAAGAAAGAGAAGTAATAAGCCACAACGAAAGTGTCAAAGCATTGCTC
AGACAGAAAGAAGAAGCAAAAAAGAAGCTGAAAGAAGTAGAAGAAGATATAAAACTGGCCGAACAGCAAATAAACGAAGT
AAAAACTTTGATAGAATATGCAAAAGCATTCAATGCCAAAAAATTAGAACTAGAAGCAACAGAGATAAATAAATACCTGA
ACAAAGTATCACTTCAGCTCTGGAAAATTGTTCAGAGCACAGGAGAAATTAAAGACGACTTCAAAATTCTCTACGATGGA
AAAGAATTTAACATACTTTCCTACTCTGAACGAATTAAGGCAGGCCTTGAAATTGCAAACCTGATAATGGGTCTAACAAA
AATAAAATTCCCAATTTTTATAGACAATGCAGAAAGCATTACAGAATATACTGCACCAAACACACAAATACTTGAGTCCA
TAGTAAAAAAAGGAACAAAAAAACTAGAAATAAAAACTGGCAGGAGTTAA

Upstream 100 bases:

>100_bases
GGGCTATCTACTTTGACAGAGATCTAATACTTTTTGACTTATTCATGTCAAAAGCAAATTTAGAAGATATAAAAATCGAA
AAAAGAAGGGGGAAAACAAG

Downstream 100 bases:

>100_bases
TCTCCTGCTGGTTTATTTTTAAAATATAGATGTTGTTTTGCAAAAAAAAAGAGTTATAATAAAAGGAGGAGAACAAAAAA
TGGTGGTGAGAATCATGGAT

Product: DNA repair ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MIIKSITLKNFKSHKNTIINFNDKNTVIYGDNGTGKTSIGEAIAWCLTGANLFGTENVTNKLVTIGKNEMSVTLVIEKDG
KEYEITRSKKKNEIEITINGVKSTQIDLYTQFVQDKDIFFTVFNPLYFTTLAPRDAKAILYKVLPEVSNEEVFEKLSPEV
AETLKKNGFNNANTFIEKQREILKDWEDGLLKSEGNIEILRQIINAKIPEMKSFDETQLKELEKKLMEFQKNQNIEIEKE
LAILKEQYKNPPIEKPQLKDTSILQKTREELLQEYKQIQEQIKNLKPQYITCNKCGNKIDVTAKEKQLLLAKLQEIKEKG
TKTAAELKAVIEENEKAEKEFKEKVNKYRKALEIKIKRLENALNTNANKEQIQQIMQQIERLRFEEREVISHNESVKALL
RQKEEAKKKLKEVEEDIKLAEQQINEVKTLIEYAKAFNAKKLELEATEINKYLNKVSLQLWKIVQSTGEIKDDFKILYDG
KEFNILSYSERIKAGLEIANLIMGLTKIKFPIFIDNAESITEYTAPNTQILESIVKKGTKKLEIKTGRS

Sequences:

>Translated_549_residues
MIIKSITLKNFKSHKNTIINFNDKNTVIYGDNGTGKTSIGEAIAWCLTGANLFGTENVTNKLVTIGKNEMSVTLVIEKDG
KEYEITRSKKKNEIEITINGVKSTQIDLYTQFVQDKDIFFTVFNPLYFTTLAPRDAKAILYKVLPEVSNEEVFEKLSPEV
AETLKKNGFNNANTFIEKQREILKDWEDGLLKSEGNIEILRQIINAKIPEMKSFDETQLKELEKKLMEFQKNQNIEIEKE
LAILKEQYKNPPIEKPQLKDTSILQKTREELLQEYKQIQEQIKNLKPQYITCNKCGNKIDVTAKEKQLLLAKLQEIKEKG
TKTAAELKAVIEENEKAEKEFKEKVNKYRKALEIKIKRLENALNTNANKEQIQQIMQQIERLRFEEREVISHNESVKALL
RQKEEAKKKLKEVEEDIKLAEQQINEVKTLIEYAKAFNAKKLELEATEINKYLNKVSLQLWKIVQSTGEIKDDFKILYDG
KEFNILSYSERIKAGLEIANLIMGLTKIKFPIFIDNAESITEYTAPNTQILESIVKKGTKKLEIKTGRS
>Mature_549_residues
MIIKSITLKNFKSHKNTIINFNDKNTVIYGDNGTGKTSIGEAIAWCLTGANLFGTENVTNKLVTIGKNEMSVTLVIEKDG
KEYEITRSKKKNEIEITINGVKSTQIDLYTQFVQDKDIFFTVFNPLYFTTLAPRDAKAILYKVLPEVSNEEVFEKLSPEV
AETLKKNGFNNANTFIEKQREILKDWEDGLLKSEGNIEILRQIINAKIPEMKSFDETQLKELEKKLMEFQKNQNIEIEKE
LAILKEQYKNPPIEKPQLKDTSILQKTREELLQEYKQIQEQIKNLKPQYITCNKCGNKIDVTAKEKQLLLAKLQEIKEKG
TKTAAELKAVIEENEKAEKEFKEKVNKYRKALEIKIKRLENALNTNANKEQIQQIMQQIERLRFEEREVISHNESVKALL
RQKEEAKKKLKEVEEDIKLAEQQINEVKTLIEYAKAFNAKKLELEATEINKYLNKVSLQLWKIVQSTGEIKDDFKILYDG
KEFNILSYSERIKAGLEIANLIMGLTKIKFPIFIDNAESITEYTAPNTQILESIVKKGTKKLEIKTGRS

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of mre11 by unwinding and

COG id: COG0419

COG function: function code L; ATPase involved in DNA repair

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 zinc-hook domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022982
- InterPro:   IPR007517
- InterPro:   IPR013134 [H]

Pfam domain/function: PF04423 Rad50_zn_hook [H]

EC number: NA

Molecular weight: Translated: 63442; Mature: 63442

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKSITLKNFKSHKNTIINFNDKNTVIYGDNGTGKTSIGEAIAWCLTGANLFGTENVTN
CCCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH
KLVTIGKNEMSVTLVIEKDGKEYEITRSKKKNEIEITINGVKSTQIDLYTQFVQDKDIFF
HHEEECCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEE
TVFNPLYFTTLAPRDAKAILYKVLPEVSNEEVFEKLSPEVAETLKKNGFNNANTFIEKQR
EEECHHHHEECCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHH
EILKDWEDGLLKSEGNIEILRQIINAKIPEMKSFDETQLKELEKKLMEFQKNQNIEIEKE
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
LAILKEQYKNPPIEKPQLKDTSILQKTREELLQEYKQIQEQIKNLKPQYITCNKCGNKID
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEE
VTAKEKQLLLAKLQEIKEKGTKTAAELKAVIEENEKAEKEFKEKVNKYRKALEIKIKRLE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALNTNANKEQIQQIMQQIERLRFEEREVISHNESVKALLRQKEEAKKKLKEVEEDIKLA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQINEVKTLIEYAKAFNAKKLELEATEINKYLNKVSLQLWKIVQSTGEIKDDFKILYDG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
KEFNILSYSERIKAGLEIANLIMGLTKIKFPIFIDNAESITEYTAPNTQILESIVKKGTK
CCCCEECHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCC
KLEIKTGRS
EEEEECCCC
>Mature Secondary Structure
MIIKSITLKNFKSHKNTIINFNDKNTVIYGDNGTGKTSIGEAIAWCLTGANLFGTENVTN
CCCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH
KLVTIGKNEMSVTLVIEKDGKEYEITRSKKKNEIEITINGVKSTQIDLYTQFVQDKDIFF
HHEEECCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEE
TVFNPLYFTTLAPRDAKAILYKVLPEVSNEEVFEKLSPEVAETLKKNGFNNANTFIEKQR
EEECHHHHEECCCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHH
EILKDWEDGLLKSEGNIEILRQIINAKIPEMKSFDETQLKELEKKLMEFQKNQNIEIEKE
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
LAILKEQYKNPPIEKPQLKDTSILQKTREELLQEYKQIQEQIKNLKPQYITCNKCGNKID
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEE
VTAKEKQLLLAKLQEIKEKGTKTAAELKAVIEENEKAEKEFKEKVNKYRKALEIKIKRLE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALNTNANKEQIQQIMQQIERLRFEEREVISHNESVKALLRQKEEAKKKLKEVEEDIKLA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQINEVKTLIEYAKAFNAKKLELEATEINKYLNKVSLQLWKIVQSTGEIKDDFKILYDG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
KEFNILSYSERIKAGLEIANLIMGLTKIKFPIFIDNAESITEYTAPNTQILESIVKKGTK
CCCCEECHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCC
KLEIKTGRS
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA