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The map label for this gene is Gcd1.2 [H]

Identifier: 20808416

GI number: 20808416

Start: 1963170

End: 1965506

Strand: Reverse

Name: Gcd1.2 [H]

Synonym: TTE2013

Alternate gene names: 20808416

Gene position: 1965506-1963170 (Counterclockwise)

Preceding gene: 20808418

Following gene: 20808415

Centisome position: 73.08

GC content: 37.23

Gene sequence:

>2337_bases
ATGAAAGGGATAATAATGGCAGGTGGAGAGGGAAGCAGATTAAGGCCTTTAACTTTTGATATTCCAAAGCCTTTGGTGCC
TGTGGCAAATAAACCTGCGATAAAGCATATTGTAGAGCATTTGCACAAGTACGGAGTGGGGGAATTAGCAGTCACTCTTT
TTTATTTACCTCACAAGATAAAAGATTACTTGCTTGAAGAGTATGGAAATGAAATAAAGTTTTACACAGAAGAAAAGCCT
CTGGGGACTGCAGGAAGTGTGAAAAACGCGAAAGATTTCCTGAAGGAAACTTTTATTGTCATGAGCGGAGATGTAATTAC
AGATGTAAACATAAAGGAAGTATATGACTTTCACAGGAAAAAGGGTTCGAAAGTGACTTTAGTTTTAAAAAAAGTAGAAA
TTCCTTTAGAGTATGGAGTTGTAATAGTCGATGAAACAGGGAAAATAGTAAAGTTTTTAGAGAAACCGTCGTGGGGAGAG
GTTTTTAGCGATACTGTCAACACAGGGATTTACATAATTGAACCGGAAATACTTGAATTTATACCTGAAGATAGACCTTT
TGATTTTAGTAAAGACTTGTTTCCGCTTCTTTTGAAGGAAAACATTCCTATGTATGGGTACATTACAGAAGGCTACTGGT
GTGACATAGGAAATACAGCGCAGTACCTTTCAAGCCATTTTGATGTGTTGGAAGGTAAGCTGGATTTGGGTTACAGAAAA
ATCCTCCTTGAAGAAGGAAAAGTTATTGGCAAGAAGGTTTTAATGTCTTCGGGAGCAAAGTTGATTCTTCCTTTGATTAT
AGGAAATGAGGTGGTTATTGAGGAAAATGCTGTAGTAGGGCCTAATGTGGTCATAGGAAGAGGTACGATTATAAAGAAAG
GAAGTCATGTAAAAAATTCTGTACTGTGGGAAGATGTATATGTAGGGGAAAACAGCGAATTGAATGGAGCAGTGGTGTGC
AATAAGGTCAGAATAGATTCTAACGCAAGGATATTGGAAAATGCTGTAATAGGAGAAGGGGTTAGAATAAAGGCTTTTGC
AGAGATAAGACCGGATGTAAAAGTTTGGCCTTTTAAGGTTATAGAGGAAGAGGCAGTAGTCTCAAAGGATGTAGTTTGGG
GAAATGGCAGGAAAAACCTATCTTTTGGTTACAGAGGGATAAGGGGCATTTTTAATGAAGAGATAGGTCCTTATCAGGCT
GTAGAAATTGGGGAGGCCTTTGGGGATTTAATGAAAGGGAAAGTCATTGTGGGAAGTGATGAGGAACTAGCTTCCTCTCT
CATTGCCGATTTGATTGCTTACGGGCTTGCTTTTTCCGGGTGTGAAGTGTTAAAAAGCAATAGCTTTCTGCTGCCGGCTT
TAAGAGTGGGAATCAGGTTAAGAAGTGCAAAAGGAGGGGTGTATGTAGAAAGGATAGGGGAGGAAATTAGAATTTTATTT
TTGGATGGAGAGGGAATGGATATAGATAGAAATTTGGAGAAGAAGATAGAGAATAAATTAAAAATTCACGACATATCAAG
AAGAAAAATAGAAGACATAAAGCCAATAAAAGAGGTGGATGTAGAGGGAGATTATAAGGATTATCTTGTCAAAAATAGAG
CAGATTCTTTCAAGATAAAGGTTAAGCCTCATGATGAATGGACTAAAAAAGTGCTTCTGCAGATAAAAGGAGAGCAAATT
TTAGATGACCAAAACTATCACTTGAAAGTGAAATTGAAAAAGAATGGGGAAGAGATAGAACTTTATGACGAAAAAGATAG
GAAATTTGATGAAGATGAAGTGAATTATCTAAAGATGTTGATTGCCAGGGAAAAAGGTCTAAAGAAAGTTGTACTGCCTT
TTAACAGTTCCAAGTATTTGGCAGAGTTTGCAGAAGAACTTGCAGTAGAGACAGTTGTAGGAAAGATTTCACCAAGGGAC
CTTATGAGGTCGATGACTAATTTAGAAGAGGGAAGGCAGGTGTATTTTGACCTTTCTTTTGACGGGATAAACTTTTTGTT
AGAAGTGATTGAATACGTAAGGTTAAAGAATAAAAGGCTTTCGGAGATAAAAGATAGTTTTCCTCTTAGGTATAAAACAG
TCAAGAGAATAAGATGTGATTGGAAGGATAAGGGGAGAATAATAAGAGAACTGTTTGAAACCCGTAAAAATAATGTTACA
TTTTTGGATGGGCTAAGGTTTGAAGAGGATGAAGGATGGGTTCTAGTGGTTCCCGATAGCGAACTTCCTTTTTGCAATGT
GTATGTGGAGGCATTGACACCGGAGAAAGCTGAAAGGCTTTTTACAATTTATGAAAAAAAGATACAGGATATTTTATTGA
AAAATGATGGAAAGTGA

Upstream 100 bases:

>100_bases
TTTCATTTCAATTTTATGTAGCTTCAAGTTTGAAATGAATAATTTTTGCACAAATAAAGAAAATAAAAATTAGGGTCAAT
AAATTTTTTGGGGTGGTTGG

Downstream 100 bases:

>100_bases
TGTAAAGTGATAAATTAAAGAGGATGAGTAAGTTGTAACGCTTTACATCCTCTTTTTTTGTTTTAAAGGGCATTTAAGAA
GGCGGGATTTCTTTTGATGT

Product: nucleoside-diphosphate-sugar pyrophosphorylase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKGIIMAGGEGSRLRPLTFDIPKPLVPVANKPAIKHIVEHLHKYGVGELAVTLFYLPHKIKDYLLEEYGNEIKFYTEEKP
LGTAGSVKNAKDFLKETFIVMSGDVITDVNIKEVYDFHRKKGSKVTLVLKKVEIPLEYGVVIVDETGKIVKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPEDRPFDFSKDLFPLLLKENIPMYGYITEGYWCDIGNTAQYLSSHFDVLEGKLDLGYRK
ILLEEGKVIGKKVLMSSGAKLILPLIIGNEVVIEENAVVGPNVVIGRGTIIKKGSHVKNSVLWEDVYVGENSELNGAVVC
NKVRIDSNARILENAVIGEGVRIKAFAEIRPDVKVWPFKVIEEEAVVSKDVVWGNGRKNLSFGYRGIRGIFNEEIGPYQA
VEIGEAFGDLMKGKVIVGSDEELASSLIADLIAYGLAFSGCEVLKSNSFLLPALRVGIRLRSAKGGVYVERIGEEIRILF
LDGEGMDIDRNLEKKIENKLKIHDISRRKIEDIKPIKEVDVEGDYKDYLVKNRADSFKIKVKPHDEWTKKVLLQIKGEQI
LDDQNYHLKVKLKKNGEEIELYDEKDRKFDEDEVNYLKMLIAREKGLKKVVLPFNSSKYLAEFAEELAVETVVGKISPRD
LMRSMTNLEEGRQVYFDLSFDGINFLLEVIEYVRLKNKRLSEIKDSFPLRYKTVKRIRCDWKDKGRIIRELFETRKNNVT
FLDGLRFEEDEGWVLVVPDSELPFCNVYVEALTPEKAERLFTIYEKKIQDILLKNDGK

Sequences:

>Translated_778_residues
MKGIIMAGGEGSRLRPLTFDIPKPLVPVANKPAIKHIVEHLHKYGVGELAVTLFYLPHKIKDYLLEEYGNEIKFYTEEKP
LGTAGSVKNAKDFLKETFIVMSGDVITDVNIKEVYDFHRKKGSKVTLVLKKVEIPLEYGVVIVDETGKIVKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPEDRPFDFSKDLFPLLLKENIPMYGYITEGYWCDIGNTAQYLSSHFDVLEGKLDLGYRK
ILLEEGKVIGKKVLMSSGAKLILPLIIGNEVVIEENAVVGPNVVIGRGTIIKKGSHVKNSVLWEDVYVGENSELNGAVVC
NKVRIDSNARILENAVIGEGVRIKAFAEIRPDVKVWPFKVIEEEAVVSKDVVWGNGRKNLSFGYRGIRGIFNEEIGPYQA
VEIGEAFGDLMKGKVIVGSDEELASSLIADLIAYGLAFSGCEVLKSNSFLLPALRVGIRLRSAKGGVYVERIGEEIRILF
LDGEGMDIDRNLEKKIENKLKIHDISRRKIEDIKPIKEVDVEGDYKDYLVKNRADSFKIKVKPHDEWTKKVLLQIKGEQI
LDDQNYHLKVKLKKNGEEIELYDEKDRKFDEDEVNYLKMLIAREKGLKKVVLPFNSSKYLAEFAEELAVETVVGKISPRD
LMRSMTNLEEGRQVYFDLSFDGINFLLEVIEYVRLKNKRLSEIKDSFPLRYKTVKRIRCDWKDKGRIIRELFETRKNNVT
FLDGLRFEEDEGWVLVVPDSELPFCNVYVEALTPEKAERLFTIYEKKIQDILLKNDGK
>Mature_778_residues
MKGIIMAGGEGSRLRPLTFDIPKPLVPVANKPAIKHIVEHLHKYGVGELAVTLFYLPHKIKDYLLEEYGNEIKFYTEEKP
LGTAGSVKNAKDFLKETFIVMSGDVITDVNIKEVYDFHRKKGSKVTLVLKKVEIPLEYGVVIVDETGKIVKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPEDRPFDFSKDLFPLLLKENIPMYGYITEGYWCDIGNTAQYLSSHFDVLEGKLDLGYRK
ILLEEGKVIGKKVLMSSGAKLILPLIIGNEVVIEENAVVGPNVVIGRGTIIKKGSHVKNSVLWEDVYVGENSELNGAVVC
NKVRIDSNARILENAVIGEGVRIKAFAEIRPDVKVWPFKVIEEEAVVSKDVVWGNGRKNLSFGYRGIRGIFNEEIGPYQA
VEIGEAFGDLMKGKVIVGSDEELASSLIADLIAYGLAFSGCEVLKSNSFLLPALRVGIRLRSAKGGVYVERIGEEIRILF
LDGEGMDIDRNLEKKIENKLKIHDISRRKIEDIKPIKEVDVEGDYKDYLVKNRADSFKIKVKPHDEWTKKVLLQIKGEQI
LDDQNYHLKVKLKKNGEEIELYDEKDRKFDEDEVNYLKMLIAREKGLKKVVLPFNSSKYLAEFAEELAVETVVGKISPRD
LMRSMTNLEEGRQVYFDLSFDGINFLLEVIEYVRLKNKRLSEIKDSFPLRYKTVKRIRCDWKDKGRIIRELFETRKNNVT
FLDGLRFEEDEGWVLVVPDSELPFCNVYVEALTPEKAERLFTIYEKKIQDILLKNDGK

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=349, Percent_Identity=32.6647564469914, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI11761619, Length=333, Percent_Identity=32.7327327327327, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI31881779, Length=367, Percent_Identity=26.158038147139, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI45447090, Length=367, Percent_Identity=26.158038147139, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI9966779, Length=442, Percent_Identity=23.5294117647059, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI262205273, Length=170, Percent_Identity=30.5882352941176, Blast_Score=74, Evalue=7e-13,
Organism=Escherichia coli, GI1789837, Length=387, Percent_Identity=25.3229974160207, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788351, Length=192, Percent_Identity=25.5208333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790224, Length=193, Percent_Identity=24.8704663212435, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=379, Percent_Identity=33.509234828496, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17509979, Length=350, Percent_Identity=25.1428571428571, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=338, Percent_Identity=24.8520710059172, Blast_Score=102, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=332, Percent_Identity=37.0481927710843, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320417, Length=424, Percent_Identity=23.5849056603774, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355443, Length=349, Percent_Identity=34.6704871060172, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24644084, Length=349, Percent_Identity=34.6704871060172, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24653912, Length=380, Percent_Identity=23.9473684210526, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 88650; Mature: 88650

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIIMAGGEGSRLRPLTFDIPKPLVPVANKPAIKHIVEHLHKYGVGELAVTLFYLPHKI
CCCEEEECCCCCEECCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KDYLLEEYGNEIKFYTEEKPLGTAGSVKNAKDFLKETFIVMSGDVITDVNIKEVYDFHRK
HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHEEEEEECCEEECCCHHHHHHHHHC
KGSKVTLVLKKVEIPLEYGVVIVDETGKIVKFLEKPSWGEVFSDTVNTGIYIIEPEILEF
CCCEEEEEEEEEECCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHCCCEEEECHHHHHH
IPEDRPFDFSKDLFPLLLKENIPMYGYITEGYWCDIGNTAQYLSSHFDVLEGKLDLGYRK
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHCCCCCCCHHH
ILLEEGKVIGKKVLMSSGAKLILPLIIGNEVVIEENAVVGPNVVIGRGTIIKKGSHVKNS
HHHHCCHHHHHHHHHHCCCEEEEEEEECCEEEEECCCEECCCEEEECCEEEECCCCCCCC
VLWEDVYVGENSELNGAVVCNKVRIDSNARILENAVIGEGVRIKAFAEIRPDVKVWPFKV
EEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCEECCHHH
IEEEAVVSKDVVWGNGRKNLSFGYRGIRGIFNEEIGPYQAVEIGEAFGDLMKGKVIVGSD
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCC
EELASSLIADLIAYGLAFSGCEVLKSNSFLLPALRVGIRLRSAKGGVYVERIGEEIRILF
HHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEHHHHHCEEEECCCCCEEHEECCCEEEEEE
LDGEGMDIDRNLEKKIENKLKIHDISRRKIEDIKPIKEVDVEGDYKDYLVKNRADSFKIK
ECCCCCCCCCHHHHHHHCCEEEEECCHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCEEEE
VKPHDEWTKKVLLQIKGEQILDDQNYHLKVKLKKNGEEIELYDEKDRKFDEDEVNYLKML
EECCHHHHHHHHHEECCCHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
IAREKGLKKVVLPFNSSKYLAEFAEELAVETVVGKISPRDLMRSMTNLEEGRQVYFDLSF
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCCEEEEEEEC
DGINFLLEVIEYVRLKNKRLSEIKDSFPLRYKTVKRIRCDWKDKGRIIRELFETRKNNVT
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEE
FLDGLRFEEDEGWVLVVPDSELPFCNVYVEALTPEKAERLFTIYEKKIQDILLKNDGK
EEECEEEECCCCEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGIIMAGGEGSRLRPLTFDIPKPLVPVANKPAIKHIVEHLHKYGVGELAVTLFYLPHKI
CCCEEEECCCCCEECCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KDYLLEEYGNEIKFYTEEKPLGTAGSVKNAKDFLKETFIVMSGDVITDVNIKEVYDFHRK
HHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHEEEEEECCEEECCCHHHHHHHHHC
KGSKVTLVLKKVEIPLEYGVVIVDETGKIVKFLEKPSWGEVFSDTVNTGIYIIEPEILEF
CCCEEEEEEEEEECCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHCCCEEEECHHHHHH
IPEDRPFDFSKDLFPLLLKENIPMYGYITEGYWCDIGNTAQYLSSHFDVLEGKLDLGYRK
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHCCCCCCCHHH
ILLEEGKVIGKKVLMSSGAKLILPLIIGNEVVIEENAVVGPNVVIGRGTIIKKGSHVKNS
HHHHCCHHHHHHHHHHCCCEEEEEEEECCEEEEECCCEECCCEEEECCEEEECCCCCCCC
VLWEDVYVGENSELNGAVVCNKVRIDSNARILENAVIGEGVRIKAFAEIRPDVKVWPFKV
EEEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCEECCHHH
IEEEAVVSKDVVWGNGRKNLSFGYRGIRGIFNEEIGPYQAVEIGEAFGDLMKGKVIVGSD
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCC
EELASSLIADLIAYGLAFSGCEVLKSNSFLLPALRVGIRLRSAKGGVYVERIGEEIRILF
HHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEHHHHHCEEEECCCCCEEHEECCCEEEEEE
LDGEGMDIDRNLEKKIENKLKIHDISRRKIEDIKPIKEVDVEGDYKDYLVKNRADSFKIK
ECCCCCCCCCHHHHHHHCCEEEEECCHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCEEEE
VKPHDEWTKKVLLQIKGEQILDDQNYHLKVKLKKNGEEIELYDEKDRKFDEDEVNYLKML
EECCHHHHHHHHHEECCCHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
IAREKGLKKVVLPFNSSKYLAEFAEELAVETVVGKISPRDLMRSMTNLEEGRQVYFDLSF
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHCCCEEEEEEEC
DGINFLLEVIEYVRLKNKRLSEIKDSFPLRYKTVKRIRCDWKDKGRIIRELFETRKNNVT
CHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEE
FLDGLRFEEDEGWVLVVPDSELPFCNVYVEALTPEKAERLFTIYEKKIQDILLKNDGK
EEECEEEECCCCEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]