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The map label for this gene is KdpD [H]

Identifier: 20808412

GI number: 20808412

Start: 1957197

End: 1958294

Strand: Reverse

Name: KdpD [H]

Synonym: TTE2009

Alternate gene names: 20808412

Gene position: 1958294-1957197 (Counterclockwise)

Preceding gene: 20808413

Following gene: 20808411

Centisome position: 72.81

GC content: 39.53

Gene sequence:

>1098_bases
ATGAGAGAAATTGAAAGGGCAAATAAAGGAAGGCTCAAGATTTACCTTGGTGCTGCTCCTGGTGTCGGAAAGACCTACCA
CATGTTACAGGATGCCAATGAGATGAAGAAAAGAGGCATAGACGTAGTTATTGGTTTTGTAGAAACCTATGGGAGAAAAG
ACACAGAGGAGCAGATAGGGGACCTTGAGATTATTCCTTTGAAGGAAATAAATTACAAAGGTGTAATTCTTAAGGAGATG
GATTTGGAGGCAATTATTAAGAGAAAACCTCAGGTAGTCGTTGTAGATGAATTGGCTCACACAAATGCTCCTGGTTCAAA
AAATGAGAAAAGGTATCAGGACGTGTTAGAACTCATAGACAACGGCATAAGCGTTATGACGGCTGTAAACATACAGCATT
TTGAAAGCTTGAATGACTATGTAAACAGGATGACGAATGTGAAAGTTAGAGAGACCATCCCCGATAAAATTCTTGAACTG
GCTGATGAGATTGAAGTGGTGGACGTATCTCCAGAGACCTTAATTGAGAGGTTGAAAAACGGCAAAATTTATAGTCCTGA
TAAGATTGAGACAGCTCTTAATAATTTCTTCAGAGTAGGGAATTTAGCGGCTTTAAGAGAGCTGACATTGAGGGAAGTGG
CCAATGAGGTTGACGATAGGCTTTTAGAGTACAGGAATAAGAAGAAAGTCGTGGGATTAAAGGGAGCGCAGGAAAAGATA
CTGGTGTGTGTAAATTTGAGGTTTAATGCGGAATATTTGATAAGGCGTGGATATAGGCTAGCTAAAATGCTTAAGGCTGA
CCTGTTTGTGCTTCATGTCTACAACGACGATGAGCTCAAAGACCATAAAAATTTGAAAAAGTTAGATGAGATTACTATGC
TGTGCAATAAATTAGAAGCCAAGTTTTACATGGTGAAATCAAATGACCCGGCAAAGGCTATAATAAAATTTGCTGAGGAG
AATGCCATTACTCAGATTGTGGTAGGACAGTCTGTAAGAAGAAGGATAGACGAAATAATAAGAGGCTCAATTGTGAGAAG
GATAATGAAGGGGACCAAATTTATAGATGTGCTTGTAGTTGCTGATCCGAGGGGTTAA

Upstream 100 bases:

>100_bases
CGAGGGTTAATGTATTGAAACTGAATTTGAGCTTATTGGAAGAAATTAAAAAGCATAAAAAGTGAGGTAAATGGCAGTGA
AGAGGTCCCCAGACTACTTC

Downstream 100 bases:

>100_bases
TCCCCCTTTTTTTATAAAGTTTTAAGAAGGGTTGCGATATGAAAAAAGAGGAGAAAAAGGGGTATATATCGGCTACTGAA
GTAAATCAGTTTCTTTACTG

Product: osmosensitive K+ channel histidine kinase sensor subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MREIERANKGRLKIYLGAAPGVGKTYHMLQDANEMKKRGIDVVIGFVETYGRKDTEEQIGDLEIIPLKEINYKGVILKEM
DLEAIIKRKPQVVVVDELAHTNAPGSKNEKRYQDVLELIDNGISVMTAVNIQHFESLNDYVNRMTNVKVRETIPDKILEL
ADEIEVVDVSPETLIERLKNGKIYSPDKIETALNNFFRVGNLAALRELTLREVANEVDDRLLEYRNKKKVVGLKGAQEKI
LVCVNLRFNAEYLIRRGYRLAKMLKADLFVLHVYNDDELKDHKNLKKLDEITMLCNKLEAKFYMVKSNDPAKAIIKFAEE
NAITQIVVGQSVRRRIDEIIRGSIVRRIMKGTKFIDVLVVADPRG

Sequences:

>Translated_365_residues
MREIERANKGRLKIYLGAAPGVGKTYHMLQDANEMKKRGIDVVIGFVETYGRKDTEEQIGDLEIIPLKEINYKGVILKEM
DLEAIIKRKPQVVVVDELAHTNAPGSKNEKRYQDVLELIDNGISVMTAVNIQHFESLNDYVNRMTNVKVRETIPDKILEL
ADEIEVVDVSPETLIERLKNGKIYSPDKIETALNNFFRVGNLAALRELTLREVANEVDDRLLEYRNKKKVVGLKGAQEKI
LVCVNLRFNAEYLIRRGYRLAKMLKADLFVLHVYNDDELKDHKNLKKLDEITMLCNKLEAKFYMVKSNDPAKAIIKFAEE
NAITQIVVGQSVRRRIDEIIRGSIVRRIMKGTKFIDVLVVADPRG
>Mature_365_residues
MREIERANKGRLKIYLGAAPGVGKTYHMLQDANEMKKRGIDVVIGFVETYGRKDTEEQIGDLEIIPLKEINYKGVILKEM
DLEAIIKRKPQVVVVDELAHTNAPGSKNEKRYQDVLELIDNGISVMTAVNIQHFESLNDYVNRMTNVKVRETIPDKILEL
ADEIEVVDVSPETLIERLKNGKIYSPDKIETALNNFFRVGNLAALRELTLREVANEVDDRLLEYRNKKKVVGLKGAQEKI
LVCVNLRFNAEYLIRRGYRLAKMLKADLFVLHVYNDDELKDHKNLKKLDEITMLCNKLEAKFYMVKSNDPAKAIIKFAEE
NAITQIVVGQSVRRRIDEIIRGSIVRRIMKGTKFIDVLVVADPRG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=365, Percent_Identity=37.8082191780822, Blast_Score=266, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41791; Mature: 41791

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00216 SUGAR_TRANSPORT_1 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIERANKGRLKIYLGAAPGVGKTYHMLQDANEMKKRGIDVVIGFVETYGRKDTEEQIG
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHCCCCCCHHHHC
DLEIIPLKEINYKGVILKEMDLEAIIKRKPQVVVVDELAHTNAPGSKNEKRYQDVLELID
CEEEEEECCCCCCEEEEECCCHHHHHHCCCCEEEEECHHCCCCCCCCCHHHHHHHHHHHH
NGISVMTAVNIQHFESLNDYVNRMTNVKVRETIPDKILELADEIEVVDVSPETLIERLKN
CCCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHC
GKIYSPDKIETALNNFFRVGNLAALRELTLREVANEVDDRLLEYRNKKKVVGLKGAQEKI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEE
LVCVNLRFNAEYLIRRGYRLAKMLKADLFVLHVYNDDELKDHKNLKKLDEITMLCNKLEA
EEEEEEEECHHHHHHCCHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
KFYMVKSNDPAKAIIKFAEENAITQIVVGQSVRRRIDEIIRGSIVRRIMKGTKFIDVLVV
EEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ADPRG
ECCCC
>Mature Secondary Structure
MREIERANKGRLKIYLGAAPGVGKTYHMLQDANEMKKRGIDVVIGFVETYGRKDTEEQIG
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEEEHHHHCCCCCCHHHHC
DLEIIPLKEINYKGVILKEMDLEAIIKRKPQVVVVDELAHTNAPGSKNEKRYQDVLELID
CEEEEEECCCCCCEEEEECCCHHHHHHCCCCEEEEECHHCCCCCCCCCHHHHHHHHHHHH
NGISVMTAVNIQHFESLNDYVNRMTNVKVRETIPDKILELADEIEVVDVSPETLIERLKN
CCCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHC
GKIYSPDKIETALNNFFRVGNLAALRELTLREVANEVDDRLLEYRNKKKVVGLKGAQEKI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEE
LVCVNLRFNAEYLIRRGYRLAKMLKADLFVLHVYNDDELKDHKNLKKLDEITMLCNKLEA
EEEEEEEECHHHHHHCCHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
KFYMVKSNDPAKAIIKFAEENAITQIVVGQSVRRRIDEIIRGSIVRRIMKGTKFIDVLVV
EEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ADPRG
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]