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The map label for this gene is Dak1.2 [H]

Identifier: 20808400

GI number: 20808400

Start: 1945145

End: 1946143

Strand: Reverse

Name: Dak1.2 [H]

Synonym: TTE1997

Alternate gene names: 20808400

Gene position: 1946143-1945145 (Counterclockwise)

Preceding gene: 20808401

Following gene: 20808399

Centisome position: 72.36

GC content: 43.24

Gene sequence:

>999_bases
ATGAAAAAGTTAATTAACAACCCTGAGAGCGTTGTAAAGGAGATGATTGAGGGGCTTTTGGCAGCTCATCCCAATTATCT
CAGAAAGCTTGAGAATATCAATGTGATTGTGAGAAAAGATGCGCCAGTTGAAGGTAAAGTAGGACTTGTCAGTGGTGGAG
GAAGTGGACACGAACCTGCCCACGCAGGATACGTGGGTTACGGAATGCTTGACGCTGCTTGCCCTGGAGAAGTCTTTACT
TCACCGACACCTGACCAGATGTATGAGGCTATTAAGGCTGTAAACTCTGGGAAGGGCGTGCTGCTTATCATTAAAAATTA
CACGGGAGACGTAATGAATTTTGAAATGGCAAGAGAAATGGCGCAAGCAGAGGGAATAGAGGTGGACCAGGTTATAGTAA
ACGATGATGTGGCAGTGGAAAACAGCACTTGGACGCAAGGCAGACGCGGTATAGCAGGAACTGTTTTTGTCCATAAGATT
GCCGGAGCAAAAGCTCAAGAGGGAGCTAGCCTTAAGGAGGTAAAGAGGGTAGCTGAAAAAGTCATAGCGAATGTCCGTTC
GATGGGAATGGCGTTAACACCTTGTACTGTGCCTGCAGCGGGTAAGCCAAGTTTTACTCTTCAAGAAGATGAGATGGAGA
TTGGAATAGGCATACACGGAGAGCCTGGTACGCACAGAGAGAAGATAAAACACGTTGATGAAATAGTGGAGCATTTAATG
GACAAAATAATAAATGACCTTCCTTATAAATCAGGCGATGAAGTGGCTGTAATGATAAATGGAATGGGTGGAACTCCTCT
GATGGAGCTTTATATCGCTAACAGAAAAGTCGCAGAAATTCTAAAAGAAAAGGATATAAAAGTTTACAAGACTTATGTGG
GAGAATTTATGACTTCTCTTGAGATGAGCGGCTTTTCTATAACTTTGTTAAAGCTGGATGAGGAGTTAAAGGCATTGTTG
GATGCAAAGGCTGATACGCCAGCATTTAAACAACTATAA

Upstream 100 bases:

>100_bases
TTTTATTTTTGGGGAAAATAAGCAAAAAAAAACTGGCATGGTTTTTGCATAATAATAAAGCAAAAGAATTAAAGTAATTT
ACTGTGGGGAGGTACTTTTC

Downstream 100 bases:

>100_bases
TTTTCAGGAGGTAGGAAGTATAAATGGTTATTACAAAGGAAGATGTGCTAAAAGTTATAGATAAAATTGTGGAAGTGATA
AGGGAAAATAAAGAATATCT

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKLINNPESVVKEMIEGLLAAHPNYLRKLENINVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGEVFT
SPTPDQMYEAIKAVNSGKGVLLIIKNYTGDVMNFEMAREMAQAEGIEVDQVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLKEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLQEDEMEIGIGIHGEPGTHREKIKHVDEIVEHLM
DKIINDLPYKSGDEVAVMINGMGGTPLMELYIANRKVAEILKEKDIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKALL
DAKADTPAFKQL

Sequences:

>Translated_332_residues
MKKLINNPESVVKEMIEGLLAAHPNYLRKLENINVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGEVFT
SPTPDQMYEAIKAVNSGKGVLLIIKNYTGDVMNFEMAREMAQAEGIEVDQVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLKEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLQEDEMEIGIGIHGEPGTHREKIKHVDEIVEHLM
DKIINDLPYKSGDEVAVMINGMGGTPLMELYIANRKVAEILKEKDIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKALL
DAKADTPAFKQL
>Mature_332_residues
MKKLINNPESVVKEMIEGLLAAHPNYLRKLENINVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGEVFT
SPTPDQMYEAIKAVNSGKGVLLIIKNYTGDVMNFEMAREMAQAEGIEVDQVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLKEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLQEDEMEIGIGIHGEPGTHREKIKHVDEIVEHLM
DKIINDLPYKSGDEVAVMINGMGGTPLMELYIANRKVAEILKEKDIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKALL
DAKADTPAFKQL

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=336, Percent_Identity=42.8571428571429, Blast_Score=269, Evalue=3e-72,
Organism=Escherichia coli, GI87081857, Length=354, Percent_Identity=46.045197740113, Blast_Score=333, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17565018, Length=328, Percent_Identity=35.6707317073171, Blast_Score=221, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6321055, Length=314, Percent_Identity=42.3566878980892, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6323570, Length=323, Percent_Identity=38.6996904024768, Blast_Score=195, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 36023; Mature: 36023

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLINNPESVVKEMIEGLLAAHPNYLRKLENINVIVRKDAPVEGKVGLVSGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCCCC
HAGYVGYGMLDAACPGEVFTSPTPDQMYEAIKAVNSGKGVLLIIKNYTGDVMNFEMAREM
CCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
AQAEGIEVDQVIVNDDVAVENSTWTQGRRGIAGTVFVHKIAGAKAQEGASLKEVKRVAEK
HHHCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIANVRSMGMALTPCTVPAAGKPSFTLQEDEMEIGIGIHGEPGTHREKIKHVDEIVEHLM
HHHHHHHCCEEECCCCCCCCCCCCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
DKIINDLPYKSGDEVAVMINGMGGTPLMELYIANRKVAEILKEKDIKVYKTYVGEFMTSL
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EMSGFSITLLKLDEELKALLDAKADTPAFKQL
HCCCCEEEEEECCHHHHHHHHCCCCCCHHHCC
>Mature Secondary Structure
MKKLINNPESVVKEMIEGLLAAHPNYLRKLENINVIVRKDAPVEGKVGLVSGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCCCC
HAGYVGYGMLDAACPGEVFTSPTPDQMYEAIKAVNSGKGVLLIIKNYTGDVMNFEMAREM
CCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
AQAEGIEVDQVIVNDDVAVENSTWTQGRRGIAGTVFVHKIAGAKAQEGASLKEVKRVAEK
HHHCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIANVRSMGMALTPCTVPAAGKPSFTLQEDEMEIGIGIHGEPGTHREKIKHVDEIVEHLM
HHHHHHHCCEEECCCCCCCCCCCCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
DKIINDLPYKSGDEVAVMINGMGGTPLMELYIANRKVAEILKEKDIKVYKTYVGEFMTSL
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EMSGFSITLLKLDEELKALLDAKADTPAFKQL
HCCCCEEEEEECCHHHHHHHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]