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The map label for this gene is FtsW3 [H]

Identifier: 20808372

GI number: 20808372

Start: 1914795

End: 1916039

Strand: Reverse

Name: FtsW3 [H]

Synonym: TTE1968

Alternate gene names: 20808372

Gene position: 1916039-1914795 (Counterclockwise)

Preceding gene: 20808373

Following gene: 20808371

Centisome position: 71.24

GC content: 39.2

Gene sequence:

>1245_bases
ATGGATGAATATGTAAAAACAGGATCTAAGGCTTTAAAAGACGTTTTCTGGATATTTGTCATAGCCTTTGCACTTTTATT
TATGCACAGAAAACCGGAGGAGGCTAACACAATATACTATACACTTGCTTTTCCTGTCTTAATTTTTATTGTCTATTACT
TGCATGTGAGGCTTTTCCCATTGGGAGAAATACAATTTGTAATCCTCACAGCCTTTTTAACTGAAATGGGGCTCATAATG
ATATATAGAGTTGCTCCAGAACTTCTTGTAAAGCAGATAATCTGGATCGCTATAGGTTTTGGCCTTTATTTCATAGCTTC
ATATCTTTTTAAACATTACGGATGGCTTTACAATTTAAAGTACGGAGAGTACATCTATATTTTTTTGGCAGTAGGGCTTA
TAATTTCTACTCTCTTTTTTGGAAAAGAAATAGGAGGAGCGAAGAACTGGCTTACTTTCGATGGGATATACGTGCAGCCT
GCAGAAGCTGCAAAAGTCATATATATAATTTTCCTTGCCAGGTATTTGAAAGACAAAAGAGATTTGAAAAATATCCTTAT
ACTGGGAGCTATAACGATAGGAATTGCTGGAATTTTCGCTTTAGAAAAAGACCTTGGAATGGCTTTTTTGTTTTACACTA
CCACAGTTCTCATGGTTTTTTTAGTGACTTCTAACCTTTTTTATGTAGCCTCAGGATTTGGACTTATGGCAATTGGCGGC
ATTTTGGCCTATTTTCTCTTCTGGCACGTAAGAGTGAGGATTGAAGCTTGGCTAAATCCCTGGATGGATGTTCCGGGGAA
GACGTATCAAATCGTGCAGTCCCTTTTCGCAATTGCTGCGGGAGGCTTTTTTGGAACGGGGCTGGGAATGGGGCATCCTG
AATATATACCCGTTGTTGCCAGCGACTTCATATTCTCTGCTATCTGTGAGGAATTTGGTATTTTAGGAGGAATTGCCATA
ATACTGGTGTATTTTGTTATAATGTACAGAGGAATTAAGGTGGCTTTGGAGGCAAGAGATGAGTTTGGCGCTTTGCTGGC
GGCAGGTCTTATTTCCATGTTTAGCCTTCAAGTTTTTACTATCATAGGAGGGGTTATAAAGTTCATACCTCTTACAGGAG
TTACTCTACCTTTTGTGAGCTACGGGGGAAGTTCAATGGTGATGAGCTTTTTTACACTGGGAATGCTAAACGGCATTTCC
GTCGGGGAGGAGGAAGAAGATGTCCAATTTGAAGCGCAATATTAA

Upstream 100 bases:

>100_bases
TTGTGAATGGCAAGAGGGTGAAGGTCGCTAGGATTAAAAATGGCGACATAATCACCCTTGGGGATGTTGATTTAAAGTTT
ATAGTTTAGGGTGAAATGAA

Downstream 100 bases:

>100_bases
AATACTCTTTGGAATCTTTGCCCTCCTCTTTTTTAGTTTGATTGCGTATTTGACATATTTTCAACTGTATGAAAGGGATA
AATTGATTACCAGCTCTTAC

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MDEYVKTGSKALKDVFWIFVIAFALLFMHRKPEEANTIYYTLAFPVLIFIVYYLHVRLFPLGEIQFVILTAFLTEMGLIM
IYRVAPELLVKQIIWIAIGFGLYFIASYLFKHYGWLYNLKYGEYIYIFLAVGLIISTLFFGKEIGGAKNWLTFDGIYVQP
AEAAKVIYIIFLARYLKDKRDLKNILILGAITIGIAGIFALEKDLGMAFLFYTTTVLMVFLVTSNLFYVASGFGLMAIGG
ILAYFLFWHVRVRIEAWLNPWMDVPGKTYQIVQSLFAIAAGGFFGTGLGMGHPEYIPVVASDFIFSAICEEFGILGGIAI
ILVYFVIMYRGIKVALEARDEFGALLAAGLISMFSLQVFTIIGGVIKFIPLTGVTLPFVSYGGSSMVMSFFTLGMLNGIS
VGEEEEDVQFEAQY

Sequences:

>Translated_414_residues
MDEYVKTGSKALKDVFWIFVIAFALLFMHRKPEEANTIYYTLAFPVLIFIVYYLHVRLFPLGEIQFVILTAFLTEMGLIM
IYRVAPELLVKQIIWIAIGFGLYFIASYLFKHYGWLYNLKYGEYIYIFLAVGLIISTLFFGKEIGGAKNWLTFDGIYVQP
AEAAKVIYIIFLARYLKDKRDLKNILILGAITIGIAGIFALEKDLGMAFLFYTTTVLMVFLVTSNLFYVASGFGLMAIGG
ILAYFLFWHVRVRIEAWLNPWMDVPGKTYQIVQSLFAIAAGGFFGTGLGMGHPEYIPVVASDFIFSAICEEFGILGGIAI
ILVYFVIMYRGIKVALEARDEFGALLAAGLISMFSLQVFTIIGGVIKFIPLTGVTLPFVSYGGSSMVMSFFTLGMLNGIS
VGEEEEDVQFEAQY
>Mature_414_residues
MDEYVKTGSKALKDVFWIFVIAFALLFMHRKPEEANTIYYTLAFPVLIFIVYYLHVRLFPLGEIQFVILTAFLTEMGLIM
IYRVAPELLVKQIIWIAIGFGLYFIASYLFKHYGWLYNLKYGEYIYIFLAVGLIISTLFFGKEIGGAKNWLTFDGIYVQP
AEAAKVIYIIFLARYLKDKRDLKNILILGAITIGIAGIFALEKDLGMAFLFYTTTVLMVFLVTSNLFYVASGFGLMAIGG
ILAYFLFWHVRVRIEAWLNPWMDVPGKTYQIVQSLFAIAAGGFFGTGLGMGHPEYIPVVASDFIFSAICEEFGILGGIAI
ILVYFVIMYRGIKVALEARDEFGALLAAGLISMFSLQVFTIIGGVIKFIPLTGVTLPFVSYGGSSMVMSFFTLGMLNGIS
VGEEEEDVQFEAQY

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=288, Percent_Identity=31.9444444444444, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786853, Length=296, Percent_Identity=31.0810810810811, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46468; Mature: 46468

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEYVKTGSKALKDVFWIFVIAFALLFMHRKPEEANTIYYTLAFPVLIFIVYYLHVRLFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCC
LGEIQFVILTAFLTEMGLIMIYRVAPELLVKQIIWIAIGFGLYFIASYLFKHYGWLYNLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
YGEYIYIFLAVGLIISTLFFGKEIGGAKNWLTFDGIYVQPAEAAKVIYIIFLARYLKDKR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEECCHHHHHHHHHHHHHHHHHHHH
DLKNILILGAITIGIAGIFALEKDLGMAFLFYTTTVLMVFLVTSNLFYVASGFGLMAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHH
ILAYFLFWHVRVRIEAWLNPWMDVPGKTYQIVQSLFAIAAGGFFGTGLGMGHPEYIPVVA
HHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEHHHH
SDFIFSAICEEFGILGGIAIILVYFVIMYRGIKVALEARDEFGALLAAGLISMFSLQVFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECHHHHHHHHHHHHHHHHHHHHHH
IIGGVIKFIPLTGVTLPFVSYGGSSMVMSFFTLGMLNGISVGEEEEDVQFEAQY
HHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MDEYVKTGSKALKDVFWIFVIAFALLFMHRKPEEANTIYYTLAFPVLIFIVYYLHVRLFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCC
LGEIQFVILTAFLTEMGLIMIYRVAPELLVKQIIWIAIGFGLYFIASYLFKHYGWLYNLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
YGEYIYIFLAVGLIISTLFFGKEIGGAKNWLTFDGIYVQPAEAAKVIYIIFLARYLKDKR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEECCHHHHHHHHHHHHHHHHHHHH
DLKNILILGAITIGIAGIFALEKDLGMAFLFYTTTVLMVFLVTSNLFYVASGFGLMAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHH
ILAYFLFWHVRVRIEAWLNPWMDVPGKTYQIVQSLFAIAAGGFFGTGLGMGHPEYIPVVA
HHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEHHHH
SDFIFSAICEEFGILGGIAIILVYFVIMYRGIKVALEARDEFGALLAAGLISMFSLQVFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECHHHHHHHHHHHHHHHHHHHHHH
IIGGVIKFIPLTGVTLPFVSYGGSSMVMSFFTLGMLNGISVGEEEEDVQFEAQY
HHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]