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The map label for this gene is MelB [H]

Identifier: 20808336

GI number: 20808336

Start: 1873480

End: 1874847

Strand: Reverse

Name: MelB [H]

Synonym: TTE1932

Alternate gene names: 20808336

Gene position: 1874847-1873480 (Counterclockwise)

Preceding gene: 20808337

Following gene: 20808335

Centisome position: 69.71

GC content: 33.92

Gene sequence:

>1368_bases
ATGAAGAGGGACTTGCGGAAGCATTCAAAGTCTTATCTATATGGGAATTGCATATGTTTCCTAATGCTATTTTCAGTTAG
ATTTTTGAGAAAGGAGATTAATATGACAACTTTAAAGAAGGTAGCCTATAGTTTTGGGAATTTCCCTATAGGGATAATGT
TAGAAGCTTTCGGCACTTACGTTATGTTTTTCTATATTGATGTTTTGAAAGTAGACCCCAGCTTTATAAGCCTTGCTTTT
GTCATACACGGTATAATTTTTGCAATTTTTAATCCTCTGATAGGGTATGTATCTGACAAAACAGAGACGCGATGGGGGAG
AAGAAGACCTTATATTGCTTTTGGAATTGTTCCTTTGGCTTTAGTTTTTTATGTTATATGGAGTCCTTTTGTTTCAAAAG
AGTTCCTGCCTGCTTACTTTCTCACAGTAATTATTTTGTTTGATTTTCTCTACGTGCTGGTTGGATTAAATTTGGCGGCA
CTTTTCCCAGAGATGTTTCCAAGCTTGGAAGAAAGAGCTCAAGTTTCAGCTTACAGGCAGATGTTTGGCATACTCGGATC
AATTATAGGAGTAGTACTTCCACCTATTATTTATTCGAGATATGGTTGGAACGTATTGGGTATAATTTTTGGAACATTAA
TAGCTATAGGTTTTTTTATAGCTTTTTATGGCTGTGAAGAAAAAAAGAATATAAAGATACCTTCCATTCCCGTTTTAACT
GCTTTTAAATACGTATTTTTGAATAAGGCTTTTTTACCTTTTGTAGTGGGAGGATTTTTTGCAAAATTTCTACTTACTTC
CGTCCCTGCTGCTATACCGTTTTTTACTAAATACGTATTGAGAATTCCTGAAAAAGAAGTTTCTCTTCTACTTGGCAGTA
TATTTGTAACTGCTATTCCTATGATGCTGGTTTGGAGCAAAATAACTAAAAAATTTGGTTCGAGAAAGGCGATGTTTTTG
TCTATTGGATTTTTAATACTCGTTTTCCCTGCATACTTTTTTGTAAATACTTTTGTTGAAACATTAATTGTCTCTGTAAT
TTTCGGAGCTTTGTTAGCTGGCGTTGTAATGCTTTTGGATGTTATGCTAGCAGAAGTGATAGATGAAGATACAAAAAATA
CGGGGATGAAAAGAGAAGGGATGTATACAGGAGTTTTTGGATTCATAATAAGGTTTGGATATTCACTGCAGGGAATTGTA
ATCGGAGGTATTTTAAAGTTATCAGGTTATATTCCAAATGTTTTAGAACAGCCTTCCTCTGCAATATTAGGTATTAGATT
TTTAATAAGCGGAGTGCCTGTTATTGCTCTGTTAATAGCATTTATAAGTTTTTGGTTTTATCCAATAGGTAGAAAAGAAA
ATGCATAA

Upstream 100 bases:

>100_bases
AACTGGCCATTTATTTATGAGTTTTTCTATGAACAAGCAAAAGAGTGGTATAAAGAAGGGCTAGTAAAAGGAAAGTTAAA
ATCAGAGAAAAATACTTTAA

Downstream 100 bases:

>100_bases
AGAGGGTGAAACTTGTGAGCAAAATACACTTGGGGTTTGGATTTCATGTGAATTTGTACCATTCATATAGAAGTGATACG
CCTGATGAGGCAGGTTTTGG

Product: Na+/melibiose symporter and related transporters

Products: NA

Alternate protein names: Xylose transporter [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKRDLRKHSKSYLYGNCICFLMLFSVRFLRKEINMTTLKKVAYSFGNFPIGIMLEAFGTYVMFFYIDVLKVDPSFISLAF
VIHGIIFAIFNPLIGYVSDKTETRWGRRRPYIAFGIVPLALVFYVIWSPFVSKEFLPAYFLTVIILFDFLYVLVGLNLAA
LFPEMFPSLEERAQVSAYRQMFGILGSIIGVVLPPIIYSRYGWNVLGIIFGTLIAIGFFIAFYGCEEKKNIKIPSIPVLT
AFKYVFLNKAFLPFVVGGFFAKFLLTSVPAAIPFFTKYVLRIPEKEVSLLLGSIFVTAIPMMLVWSKITKKFGSRKAMFL
SIGFLILVFPAYFFVNTFVETLIVSVIFGALLAGVVMLLDVMLAEVIDEDTKNTGMKREGMYTGVFGFIIRFGYSLQGIV
IGGILKLSGYIPNVLEQPSSAILGIRFLISGVPVIALLIAFISFWFYPIGRKENA

Sequences:

>Translated_455_residues
MKRDLRKHSKSYLYGNCICFLMLFSVRFLRKEINMTTLKKVAYSFGNFPIGIMLEAFGTYVMFFYIDVLKVDPSFISLAF
VIHGIIFAIFNPLIGYVSDKTETRWGRRRPYIAFGIVPLALVFYVIWSPFVSKEFLPAYFLTVIILFDFLYVLVGLNLAA
LFPEMFPSLEERAQVSAYRQMFGILGSIIGVVLPPIIYSRYGWNVLGIIFGTLIAIGFFIAFYGCEEKKNIKIPSIPVLT
AFKYVFLNKAFLPFVVGGFFAKFLLTSVPAAIPFFTKYVLRIPEKEVSLLLGSIFVTAIPMMLVWSKITKKFGSRKAMFL
SIGFLILVFPAYFFVNTFVETLIVSVIFGALLAGVVMLLDVMLAEVIDEDTKNTGMKREGMYTGVFGFIIRFGYSLQGIV
IGGILKLSGYIPNVLEQPSSAILGIRFLISGVPVIALLIAFISFWFYPIGRKENA
>Mature_455_residues
MKRDLRKHSKSYLYGNCICFLMLFSVRFLRKEINMTTLKKVAYSFGNFPIGIMLEAFGTYVMFFYIDVLKVDPSFISLAF
VIHGIIFAIFNPLIGYVSDKTETRWGRRRPYIAFGIVPLALVFYVIWSPFVSKEFLPAYFLTVIILFDFLYVLVGLNLAA
LFPEMFPSLEERAQVSAYRQMFGILGSIIGVVLPPIIYSRYGWNVLGIIFGTLIAIGFFIAFYGCEEKKNIKIPSIPVLT
AFKYVFLNKAFLPFVVGGFFAKFLLTSVPAAIPFFTKYVLRIPEKEVSLLLGSIFVTAIPMMLVWSKITKKFGSRKAMFL
SIGFLILVFPAYFFVNTFVETLIVSVIFGALLAGVVMLLDVMLAEVIDEDTKNTGMKREGMYTGVFGFIIRFGYSLQGIV
IGGILKLSGYIPNVLEQPSSAILGIRFLISGVPVIALLIAFISFWFYPIGRKENA

Specific function: Responsible for transport of xylose into the cell, with the concomitant uptake of protons (symport system) [H]

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1786466, Length=418, Percent_Identity=23.2057416267943, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787902, Length=450, Percent_Identity=25.1111111111111, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790561, Length=440, Percent_Identity=22.9545454545455, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082306, Length=435, Percent_Identity=22.7586206896552, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994989, Length=436, Percent_Identity=25.2293577981651, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693206, Length=440, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51341; Mature: 51341

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9573180 [H]