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The map label for this gene is PotE4 [H]

Identifier: 20808328

GI number: 20808328

Start: 1861509

End: 1862822

Strand: Direct

Name: PotE4 [H]

Synonym: TTE1924

Alternate gene names: 20808328

Gene position: 1861509-1862822 (Clockwise)

Preceding gene: 20808326

Following gene: 20808369

Centisome position: 69.22

GC content: 42.39

Gene sequence:

>1314_bases
ATGGTTGAAGAGAGAAACAAAGAAGAATTAAAGCGAGTACTGGGTACATGGGACCTAGTAGCATTTGCAATTATGACTAT
GGTGCCTATTGCGCCCATGGGGATTTACGGTGTAATAGCAGTTGTCAGTCACGGGCATGTGCCATTGGCGTATACACTTG
CTGCTATAGCCATGTACTTCACTGCTTGGGGATATGCTCAATTTGCCTTAAGGTACCCAGAAGCAGGTTCTGTTTATGCT
TATGTGCGCGAATCTGTCGGATTCCACGCAGGTTTTCTAGCAGGATGGTCAATTCTTCTAGATTACATCTTAGTTCCAGC
ACTTGTCATAATGGTTTCAGCCCTTTGGCTAGAAGCTTTGACTTCTATAAGCATGATATGGTGGGCTTTGCTCTTTATAG
TGCTAGCCACTTTTATGAACGTTTTGGGTATTCAGCTTACTTCCCGCGCCGCATGGATACTATTTGTTTTTGAACTTTTT
GTCCTCATAGTATTCATTGCAGTAGCAATATACAAAATCGCTTCTACACCTGGCTTAAGTTTTAATTTAGCTCCATTTTA
CAATCCTAGTGACTTCAGCCTTCACGCAGTCTTAGCAGGAACTTCTATTGCCGTTTTAAGCTTCTTAGGATTTGACATCA
TGACCACCCTCGCAGAAGAAACAGTAGAAGCCAGAAAAAACGTATCTCGAGCCGTTCGAATAGTAATTCCTTTAGTCGCA
TTAATGTTTGTGTTGCAGACCTATTTAGGCGCGGTGGTACACCCAGGGTATAAATTTGCAGATCCAGACGTGGCCTTCTT
TGAAATCACAAAAGAGGTAGGCGGAAACTGGCTTCAGATGCTTGCCGTGTTGGGTACCGTGCTAGCCTGGGGAATAGGAG
ATACTATGGCTGCTCAAGCAGGTATATCAAGAGTCCTTTTCTCCATGGGGCGTCAAGGCCATCTTCCAAAAATTTTTGCG
CGCATTCACCCCCAGTATAAAACTCCATATGTAGCTACAATATTTGTCGCCCTTATAACCGGGCCTTTAATCTATCTCTT
GACCTTAAAAGATATCACTTCATTAGTAAACTTTGGTGCTCTTACTTCTTTCATCGCAATGCATCTCTCTTTAGGATACA
TCTTTTTAGCAAAAGAAAAGAGACCATTAGCCGTAATTATGCCAGCTATTGGCTTTATTATTACTGCTGCCGTATGGTGG
GGATTAGATAAGCTTGCCAAAGAATTAGGATTTGCATGGCTCATATTAGGTTTCATTTATTTAGCCATTATTACCCGAGG
TTTTCGCGTCAAGACCACTCTGCCCATTGATTGA

Upstream 100 bases:

>100_bases
TAATTCAAAGTTTTAAACTTGAAAATTGCCTTTTGAGATATTATACTCTCCTTTAACTAAGCATGAAATAAACCTGAAAA
CACGAGGGAGGGGAAAGAAA

Downstream 100 bases:

>100_bases
AAAAGAGGGAACAGATTCTACAAGAGCTGTTCCCTCTTCTTATTTGTTTATTTTGTAATATTTTGTTTTACACATTCCTA
TCTTCTGCAATACTTCTTCG

Product: amino acid transporters

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MVEERNKEELKRVLGTWDLVAFAIMTMVPIAPMGIYGVIAVVSHGHVPLAYTLAAIAMYFTAWGYAQFALRYPEAGSVYA
YVRESVGFHAGFLAGWSILLDYILVPALVIMVSALWLEALTSISMIWWALLFIVLATFMNVLGIQLTSRAAWILFVFELF
VLIVFIAVAIYKIASTPGLSFNLAPFYNPSDFSLHAVLAGTSIAVLSFLGFDIMTTLAEETVEARKNVSRAVRIVIPLVA
LMFVLQTYLGAVVHPGYKFADPDVAFFEITKEVGGNWLQMLAVLGTVLAWGIGDTMAAQAGISRVLFSMGRQGHLPKIFA
RIHPQYKTPYVATIFVALITGPLIYLLTLKDITSLVNFGALTSFIAMHLSLGYIFLAKEKRPLAVIMPAIGFIITAAVWW
GLDKLAKELGFAWLILGFIYLAIITRGFRVKTTLPID

Sequences:

>Translated_437_residues
MVEERNKEELKRVLGTWDLVAFAIMTMVPIAPMGIYGVIAVVSHGHVPLAYTLAAIAMYFTAWGYAQFALRYPEAGSVYA
YVRESVGFHAGFLAGWSILLDYILVPALVIMVSALWLEALTSISMIWWALLFIVLATFMNVLGIQLTSRAAWILFVFELF
VLIVFIAVAIYKIASTPGLSFNLAPFYNPSDFSLHAVLAGTSIAVLSFLGFDIMTTLAEETVEARKNVSRAVRIVIPLVA
LMFVLQTYLGAVVHPGYKFADPDVAFFEITKEVGGNWLQMLAVLGTVLAWGIGDTMAAQAGISRVLFSMGRQGHLPKIFA
RIHPQYKTPYVATIFVALITGPLIYLLTLKDITSLVNFGALTSFIAMHLSLGYIFLAKEKRPLAVIMPAIGFIITAAVWW
GLDKLAKELGFAWLILGFIYLAIITRGFRVKTTLPID
>Mature_437_residues
MVEERNKEELKRVLGTWDLVAFAIMTMVPIAPMGIYGVIAVVSHGHVPLAYTLAAIAMYFTAWGYAQFALRYPEAGSVYA
YVRESVGFHAGFLAGWSILLDYILVPALVIMVSALWLEALTSISMIWWALLFIVLATFMNVLGIQLTSRAAWILFVFELF
VLIVFIAVAIYKIASTPGLSFNLAPFYNPSDFSLHAVLAGTSIAVLSFLGFDIMTTLAEETVEARKNVSRAVRIVIPLVA
LMFVLQTYLGAVVHPGYKFADPDVAFFEITKEVGGNWLQMLAVLGTVLAWGIGDTMAAQAGISRVLFSMGRQGHLPKIFA
RIHPQYKTPYVATIFVALITGPLIYLLTLKDITSLVNFGALTSFIAMHLSLGYIFLAKEKRPLAVIMPAIGFIITAAVWW
GLDKLAKELGFAWLILGFIYLAIITRGFRVKTTLPID

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=357, Percent_Identity=26.0504201680672, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI258614005, Length=413, Percent_Identity=23.4866828087167, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI258614003, Length=413, Percent_Identity=23.4866828087167, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI258645169, Length=413, Percent_Identity=23.4866828087167, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI181337167, Length=383, Percent_Identity=23.4986945169713, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI186910308, Length=440, Percent_Identity=23.1818181818182, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI186910306, Length=440, Percent_Identity=23.1818181818182, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI186910304, Length=440, Percent_Identity=23.1818181818182, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI33286428, Length=393, Percent_Identity=24.6819338422392, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9790235, Length=324, Percent_Identity=25.6172839506173, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI115648063, Length=422, Percent_Identity=22.2748815165877, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI115648022, Length=422, Percent_Identity=22.2748815165877, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081869, Length=438, Percent_Identity=29.2237442922374, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082023, Length=441, Percent_Identity=31.5192743764172, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1789017, Length=407, Percent_Identity=24.8157248157248, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=388, Percent_Identity=24.7422680412371, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17533459, Length=401, Percent_Identity=21.6957605985037, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666159, Length=391, Percent_Identity=23.0179028132992, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI221512776, Length=391, Percent_Identity=22.7621483375959, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24668806, Length=396, Percent_Identity=24.4949494949495, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356285, Length=396, Percent_Identity=24.4949494949495, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24668802, Length=396, Percent_Identity=24.4949494949495, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281366235, Length=418, Percent_Identity=23.6842105263158, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI116007820, Length=418, Percent_Identity=23.6842105263158, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=23.9709443099274, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=23.9709443099274, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI45550968, Length=415, Percent_Identity=24.8192771084337, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19921172, Length=415, Percent_Identity=24.8192771084337, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24667468, Length=387, Percent_Identity=22.7390180878553, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357367, Length=371, Percent_Identity=22.3719676549865, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48151; Mature: 48151

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEERNKEELKRVLGTWDLVAFAIMTMVPIAPMGIYGVIAVVSHGHVPLAYTLAAIAMYF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TAWGYAQFALRYPEAGSVYAYVRESVGFHAGFLAGWSILLDYILVPALVIMVSALWLEAL
HHHHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISMIWWALLFIVLATFMNVLGIQLTSRAAWILFVFELFVLIVFIAVAIYKIASTPGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FNLAPFYNPSDFSLHAVLAGTSIAVLSFLGFDIMTTLAEETVEARKNVSRAVRIVIPLVA
EECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFVLQTYLGAVVHPGYKFADPDVAFFEITKEVGGNWLQMLAVLGTVLAWGIGDTMAAQA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
GISRVLFSMGRQGHLPKIFARIHPQYKTPYVATIFVALITGPLIYLLTLKDITSLVNFGA
HHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSFIAMHLSLGYIFLAKEKRPLAVIMPAIGFIITAAVWWGLDKLAKELGFAWLILGFIY
HHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIITRGFRVKTTLPID
HHHHHCCCEEEEECCCC
>Mature Secondary Structure
MVEERNKEELKRVLGTWDLVAFAIMTMVPIAPMGIYGVIAVVSHGHVPLAYTLAAIAMYF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TAWGYAQFALRYPEAGSVYAYVRESVGFHAGFLAGWSILLDYILVPALVIMVSALWLEAL
HHHHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISMIWWALLFIVLATFMNVLGIQLTSRAAWILFVFELFVLIVFIAVAIYKIASTPGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FNLAPFYNPSDFSLHAVLAGTSIAVLSFLGFDIMTTLAEETVEARKNVSRAVRIVIPLVA
EECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFVLQTYLGAVVHPGYKFADPDVAFFEITKEVGGNWLQMLAVLGTVLAWGIGDTMAAQA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
GISRVLFSMGRQGHLPKIFARIHPQYKTPYVATIFVALITGPLIYLLTLKDITSLVNFGA
HHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSFIAMHLSLGYIFLAKEKRPLAVIMPAIGFIITAAVWWGLDKLAKELGFAWLILGFIY
HHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIITRGFRVKTTLPID
HHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]