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The map label for this gene is BtuC2 [C]

Identifier: 20808280

GI number: 20808280

Start: 1811511

End: 1812575

Strand: Reverse

Name: BtuC2 [C]

Synonym: TTE1868

Alternate gene names: 20808280

Gene position: 1812575-1811511 (Counterclockwise)

Preceding gene: 20808281

Following gene: 20808279

Centisome position: 67.4

GC content: 41.5

Gene sequence:

>1065_bases
TTGAGGCAGTTGATATTAGAGGCGGTACCTGAAAGTTACAATCGTTATATAAGGAGAAAAATATGGATAATACTTCTTAC
TATATTAACAACTTTTCTCCTTGCTGTGTATGCCATAAATGCTGGTTCTGCAGGACTTAGCGTGAAGGATGTAGTAAAAA
CTTTGGTAGGACAAGGGGAAGAAAGATTCAGGATAATTGTGTGGAATATAAGGATGCCGAGAATTTTATCGGCTATGATG
GCAGGAGTAGGGCTTTCTGTAGCTGGGTGTGTTACGCAAAGCATATTGAGAAATCCCTTGGCGTCCCCTTTTACTTTAGG
GATATCACAGGGTGCAGCTTTTGGAGCGGCAGTTGCCATTATCTTATTTGGGGCAGGAAGCACTACAAATCCTGATTCTG
TAATAATAAACAATCCTTATCTGGTAGTTATCTTTGCTTTTTTGGGGTCTATGGGTTCTACTGTAGTTGTGCTTATGTTG
GCAAAAAATTTTAGAGTTACACCTGAAGCGATGGTGCTTGCAGGGGTTGCCTTGGGTTCTCTATTTTCTGCCATCACGAT
GATTTTGCAGTACTTTGCAGATGATGTAAAAGTGGCTTCAATAGTTTTCTGGACTTTTGGTGATTTGGGAAGGGCTTCCT
GGAGAGATTTAACTATAATGTCTGTTGTGGTAGGGATTTCACTTATATATTTTATGTTAAACCGATGGAATTACAATGCT
TTAGACAGCGGAGAGGAGACGGCAAAGGGGTTAGGCGTAGAAGTTGAGAAGATAAGGCTTTATGGCATGTTTATGTCTTC
TCTTGTTGCTGCAGTGATTACATCTTTTGTTGGCATAATAGGGTTTGTAGGGCTTGTAGGGCCCCACATTATGAGAAGAT
TGATTGGAGGAGACCACAGGTTTTTAATTCCTGCGTCTTCTGCAATAGGTGCACTGATACTTCTTGCTTCAGATACTCTG
GGCAGGACAATAATTTCTCCGATAGTTCTGCCCGTTGGAGCTATCACTTCCTTTTTAGGTGCCCCGGTTTTCCTGTATGT
GCTTTCTAGGGGGTATAGAAGGTGA

Upstream 100 bases:

>100_bases
GGTCTATGGCGGTTTTGAAAAAATTAAATTTTAAGGGATAATCAAAGATAAATTCCTCCACTTTTTGTGGGGGAATTATA
AAGGACGAGGGGATGAAGTC

Downstream 100 bases:

>100_bases
TTTTAAACATAGATGGTATAGAATTCAGTTACACCAGCGTTCCTGTGTTAAGAAATGTGAAATTTCATCTTGAAAAAGGA
GAATTTTTATCTATTTTAGG

Product: ABC-type cobalamin/Fe3+-siderophores transport systems, permease components

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRQLILEAVPESYNRYIRRKIWIILLTILTTFLLAVYAINAGSAGLSVKDVVKTLVGQGEERFRIIVWNIRMPRILSAMM
AGVGLSVAGCVTQSILRNPLASPFTLGISQGAAFGAAVAIILFGAGSTTNPDSVIINNPYLVVIFAFLGSMGSTVVVLML
AKNFRVTPEAMVLAGVALGSLFSAITMILQYFADDVKVASIVFWTFGDLGRASWRDLTIMSVVVGISLIYFMLNRWNYNA
LDSGEETAKGLGVEVEKIRLYGMFMSSLVAAVITSFVGIIGFVGLVGPHIMRRLIGGDHRFLIPASSAIGALILLASDTL
GRTIISPIVLPVGAITSFLGAPVFLYVLSRGYRR

Sequences:

>Translated_354_residues
MRQLILEAVPESYNRYIRRKIWIILLTILTTFLLAVYAINAGSAGLSVKDVVKTLVGQGEERFRIIVWNIRMPRILSAMM
AGVGLSVAGCVTQSILRNPLASPFTLGISQGAAFGAAVAIILFGAGSTTNPDSVIINNPYLVVIFAFLGSMGSTVVVLML
AKNFRVTPEAMVLAGVALGSLFSAITMILQYFADDVKVASIVFWTFGDLGRASWRDLTIMSVVVGISLIYFMLNRWNYNA
LDSGEETAKGLGVEVEKIRLYGMFMSSLVAAVITSFVGIIGFVGLVGPHIMRRLIGGDHRFLIPASSAIGALILLASDTL
GRTIISPIVLPVGAITSFLGAPVFLYVLSRGYRR
>Mature_354_residues
MRQLILEAVPESYNRYIRRKIWIILLTILTTFLLAVYAINAGSAGLSVKDVVKTLVGQGEERFRIIVWNIRMPRILSAMM
AGVGLSVAGCVTQSILRNPLASPFTLGISQGAAFGAAVAIILFGAGSTTNPDSVIINNPYLVVIFAFLGSMGSTVVVLML
AKNFRVTPEAMVLAGVALGSLFSAITMILQYFADDVKVASIVFWTFGDLGRASWRDLTIMSVVVGISLIYFMLNRWNYNA
LDSGEETAKGLGVEVEKIRLYGMFMSSLVAAVITSFVGIIGFVGLVGPHIMRRLIGGDHRFLIPASSAIGALILLASDTL
GRTIISPIVLPVGAITSFLGAPVFLYVLSRGYRR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=292, Percent_Identity=32.8767123287671, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1790740, Length=296, Percent_Identity=33.445945945946, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786347, Length=292, Percent_Identity=33.9041095890411, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790741, Length=307, Percent_Identity=30.6188925081433, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=30.9904153354633, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786804, Length=340, Percent_Identity=28.8235294117647, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38119; Mature: 38119

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQLILEAVPESYNRYIRRKIWIILLTILTTFLLAVYAINAGSAGLSVKDVVKTLVGQGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
ERFRIIVWNIRMPRILSAMMAGVGLSVAGCVTQSILRNPLASPFTLGISQGAAFGAAVAI
CCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
ILFGAGSTTNPDSVIINNPYLVVIFAFLGSMGSTVVVLMLAKNFRVTPEAMVLAGVALGS
HHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LFSAITMILQYFADDVKVASIVFWTFGDLGRASWRDLTIMSVVVGISLIYFMLNRWNYNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDSGEETAKGLGVEVEKIRLYGMFMSSLVAAVITSFVGIIGFVGLVGPHIMRRLIGGDHR
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FLIPASSAIGALILLASDTLGRTIISPIVLPVGAITSFLGAPVFLYVLSRGYRR
EEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRQLILEAVPESYNRYIRRKIWIILLTILTTFLLAVYAINAGSAGLSVKDVVKTLVGQGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
ERFRIIVWNIRMPRILSAMMAGVGLSVAGCVTQSILRNPLASPFTLGISQGAAFGAAVAI
CCEEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
ILFGAGSTTNPDSVIINNPYLVVIFAFLGSMGSTVVVLMLAKNFRVTPEAMVLAGVALGS
HHCCCCCCCCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LFSAITMILQYFADDVKVASIVFWTFGDLGRASWRDLTIMSVVVGISLIYFMLNRWNYNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDSGEETAKGLGVEVEKIRLYGMFMSSLVAAVITSFVGIIGFVGLVGPHIMRRLIGGDHR
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FLIPASSAIGALILLASDTLGRTIISPIVLPVGAITSFLGAPVFLYVLSRGYRR
EEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]