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The map label for this gene is His2 [C]

Identifier: 20808251

GI number: 20808251

Start: 1785561

End: 1786292

Strand: Reverse

Name: His2 [C]

Synonym: TTE1835

Alternate gene names: 20808251

Gene position: 1786292-1785561 (Counterclockwise)

Preceding gene: 20808252

Following gene: 20808250

Centisome position: 66.42

GC content: 39.21

Gene sequence:

>732_bases
ATGAGGATTTTTGCAGATTATCACACCCATACGATATACAGCCACGGCAAAGGGACAATAGAAGAAAATGTGAAAAAAGC
GGTAGAGCTTGGGCTTAAGGCTATTGCTATTACTGACCATGGCCCTGCTCATGTGTTTTATGGCATGAGAAAAAAAGACT
TTAAGAAAATGAGAGATGAAATAGACAGGCTTAGGGAAAAATACTCTCAGATAAAAATACTGATGGGAGTGGAAGCGAAT
TTGATAAGTATAGAAGGGGATATTGATGTTCCCGATGAACTTCTGAAGTATCTAGATATTTTGCTTGTGGGGTACCACAC
TGGAATAGTACCGAAAAGTTTTAAAGACGCCATTGACCTTTTTGGTAAAAATATGGTGTCAAAGTATACAGGTTATCTTA
AAGAAGAGGTGAGAGAGAAAAATACAGAAGCGATGGTAAAAGCAATAAAAAAATATAGAATTGATATAATAACTCATCCT
GGAGCAAAGGTGGATATTGATACGCGAAAATTGGCCAGAGCAGCAAAAGAAAGTAGAACAGCACTGGAGATTAACTCGAG
TCACGGATACCTGACAGTGGAGTATGTAAAGATAGCAAAGGAAGAAGGATGTAAATTCGTCATAAACAGCGATGCCCATA
CTCCTTCTAGGGTGGGGGATTTTAAAAAGGGAATACAAATTGCGAAAGAGGCTGGACTCACTGAGGAAGACGTGATAAAC
GCCGAGAGGTGA

Upstream 100 bases:

>100_bases
CAACTTGATTGAGTATATCCAGAAAGTAGTAAAAGAGAAATTTGGAGTTGAGCTTATGCCTGAGATAAAAATTGTGGGGG
AAAAATAGGAGAGAGAACAA

Downstream 100 bases:

>100_bases
TAAATTATGAGGTTTGTGATAATAACAGGGCTTTCCGGTGCAGGAAAGACGCAGGCTTTAAAGGCGATGGAGGATATGGG
ATTTTTTTGCATAGATAATT

Product: PHP family histidinol phosphatase/hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRIFADYHTHTIYSHGKGTIEENVKKAVELGLKAIAITDHGPAHVFYGMRKKDFKKMRDEIDRLREKYSQIKILMGVEAN
LISIEGDIDVPDELLKYLDILLVGYHTGIVPKSFKDAIDLFGKNMVSKYTGYLKEEVREKNTEAMVKAIKKYRIDIITHP
GAKVDIDTRKLARAAKESRTALEINSSHGYLTVEYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQIAKEAGLTEEDVIN
AER

Sequences:

>Translated_243_residues
MRIFADYHTHTIYSHGKGTIEENVKKAVELGLKAIAITDHGPAHVFYGMRKKDFKKMRDEIDRLREKYSQIKILMGVEAN
LISIEGDIDVPDELLKYLDILLVGYHTGIVPKSFKDAIDLFGKNMVSKYTGYLKEEVREKNTEAMVKAIKKYRIDIITHP
GAKVDIDTRKLARAAKESRTALEINSSHGYLTVEYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQIAKEAGLTEEDVIN
AER
>Mature_243_residues
MRIFADYHTHTIYSHGKGTIEENVKKAVELGLKAIAITDHGPAHVFYGMRKKDFKKMRDEIDRLREKYSQIKILMGVEAN
LISIEGDIDVPDELLKYLDILLVGYHTGIVPKSFKDAIDLFGKNMVSKYTGYLKEEVREKNTEAMVKAIKKYRIDIITHP
GAKVDIDTRKLARAAKESRTALEINSSHGYLTVEYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQIAKEAGLTEEDVIN
AER

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP family [H]

Homologues:

Organism=Escherichia coli, GI1787271, Length=251, Percent_Identity=26.2948207171315, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: NA

Molecular weight: Translated: 27499; Mature: 27499

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFADYHTHTIYSHGKGTIEENVKKAVELGLKAIAITDHGPAHVFYGMRKKDFKKMRDE
CEEEECCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHEECCCHHHHHHHHHH
IDRLREKYSQIKILMGVEANLISIEGDIDVPDELLKYLDILLVGYHTGIVPKSFKDAIDL
HHHHHHHHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FGKNMVSKYTGYLKEEVREKNTEAMVKAIKKYRIDIITHPGAKVDIDTRKLARAAKESRT
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCEEECCHHHHHHHHHHCCC
ALEINSSHGYLTVEYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQIAKEAGLTEEDVIN
EEEEECCCCEEEEHEEEEHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCC
AER
CCC
>Mature Secondary Structure
MRIFADYHTHTIYSHGKGTIEENVKKAVELGLKAIAITDHGPAHVFYGMRKKDFKKMRDE
CEEEECCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCHHHEECCCHHHHHHHHHH
IDRLREKYSQIKILMGVEANLISIEGDIDVPDELLKYLDILLVGYHTGIVPKSFKDAIDL
HHHHHHHHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FGKNMVSKYTGYLKEEVREKNTEAMVKAIKKYRIDIITHPGAKVDIDTRKLARAAKESRT
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCEEECCHHHHHHHHHHCCC
ALEINSSHGYLTVEYVKIAKEEGCKFVINSDAHTPSRVGDFKKGIQIAKEAGLTEEDVIN
EEEEECCCCEEEEHEEEEHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCC
AER
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA