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The map label for this gene is AroC

Identifier: 20808136

GI number: 20808136

Start: 1661646

End: 1662698

Strand: Reverse

Name: AroC

Synonym: TTE1711

Alternate gene names: 20808136

Gene position: 1662698-1661646 (Counterclockwise)

Preceding gene: 20808137

Following gene: 20808135

Centisome position: 61.82

GC content: 42.17

Gene sequence:

>1053_bases
ATGAGATATCTTACAGCTGGAGAATCACACGGGGAGGCTTTGATTGCCATTATTGAAGGGCTTCCTTCAAATCTTTTTAT
TGATGCAGAATTTATCAATAAAGAGCTGGAAAGAAGACAAAAAGGCTACGGCAGAGGAGGAAGGATGGCTATTGAAAAAG
ATGAAATACATATAATAAGTGGGGTAAGGGATGGGAAGACTACTGGTGCCCCTCTTGCAATGGAGATTAAAAATAGGGAT
TATAAAAACTGGAAGGATAAAAAGGTTCCTCCTGTCACAAGGCCCAGGCCAGGACATGCAGATTTACCCGGTTCTATTAA
GTATAACCAGAGGGATATAAGAAATATTTTGGAAAGAGCCAGTGCCAGAGAGACGGCGGCAAGGGTGGCAGTTGGAAGTG
TTGCCAAGCTTCTCTTGAAAGAATTGAATATATCTTTAAAAAGCAGAGTTTTGGAGATTGGAGGAGCAAAAAGAGAAGAA
AAGTGGAAAAGGCTTATTGAAAAAGCGAAAAAAGAAGGGGATACTCTGGGAGGAATAATAGAGATTGTGATTGAAGGGGT
GCCTGTTGGGCTGGGAAGCCATGCTCAGTGGGATAGAAAGTTGGATGCGTTACTCGCTTATCATGTGATGAGCGTTCAAG
GCATAAAAGGTGTTGAATTTGGACTGGGATTTGAGGCGGCAAGACTTCCCGGATCGCTGGTGCACGATGATATATATTAC
AAGGAAAACGAGGGTTTTTATAGAAAGACGAATAATGCCGGAGGCATTGAGGGAGGCATGTCAAACGGGAATCCTATAGT
GATAAGGGCTGCTATGAAGCCAATTCCCACTCTTTTACGGCCTCTTGACTCTGTGGATATAGCTACAAAAGAAGAGACAA
AAGCTATTTATGAAAGGTCGGATGTCACTGCTGTTGAAGCTGCTGCTTGTGTTTTGGAGGCTGTCTGTGCATGGGTGATT
GCTGATGAATGCCTTAAAAAATTTGGCGGTGATTCAGTTGAGGAGCTAAAAAGAAACTATGATACTTATTTAGCATATGT
GAGAAGTTTTTGA

Upstream 100 bases:

>100_bases
GTGTTTACAGGTATAGTGAGAATTCTCGTGAGCCTTCTTTACTTTGTGGTGGCATCCTATGAAGAAAAGATAGAGGAAGA
AGAAAAGGTAGGGGGATAAG

Downstream 100 bases:

>100_bases
ATGATTAACAATAAGTACAATTAAAGGGGGAAGAGGTATGTTAATCAATACCTCGAAGCACGAAGTTTATTATCAGGCAG
GTTACTCTATTGGCAGTCAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRYLTAGESHGEALIAIIEGLPSNLFIDAEFINKELERRQKGYGRGGRMAIEKDEIHIISGVRDGKTTGAPLAMEIKNRD
YKNWKDKKVPPVTRPRPGHADLPGSIKYNQRDIRNILERASARETAARVAVGSVAKLLLKELNISLKSRVLEIGGAKREE
KWKRLIEKAKKEGDTLGGIIEIVIEGVPVGLGSHAQWDRKLDALLAYHVMSVQGIKGVEFGLGFEAARLPGSLVHDDIYY
KENEGFYRKTNNAGGIEGGMSNGNPIVIRAAMKPIPTLLRPLDSVDIATKEETKAIYERSDVTAVEAAACVLEAVCAWVI
ADECLKKFGGDSVEELKRNYDTYLAYVRSF

Sequences:

>Translated_350_residues
MRYLTAGESHGEALIAIIEGLPSNLFIDAEFINKELERRQKGYGRGGRMAIEKDEIHIISGVRDGKTTGAPLAMEIKNRD
YKNWKDKKVPPVTRPRPGHADLPGSIKYNQRDIRNILERASARETAARVAVGSVAKLLLKELNISLKSRVLEIGGAKREE
KWKRLIEKAKKEGDTLGGIIEIVIEGVPVGLGSHAQWDRKLDALLAYHVMSVQGIKGVEFGLGFEAARLPGSLVHDDIYY
KENEGFYRKTNNAGGIEGGMSNGNPIVIRAAMKPIPTLLRPLDSVDIATKEETKAIYERSDVTAVEAAACVLEAVCAWVI
ADECLKKFGGDSVEELKRNYDTYLAYVRSF
>Mature_350_residues
MRYLTAGESHGEALIAIIEGLPSNLFIDAEFINKELERRQKGYGRGGRMAIEKDEIHIISGVRDGKTTGAPLAMEIKNRD
YKNWKDKKVPPVTRPRPGHADLPGSIKYNQRDIRNILERASARETAARVAVGSVAKLLLKELNISLKSRVLEIGGAKREE
KWKRLIEKAKKEGDTLGGIIEIVIEGVPVGLGSHAQWDRKLDALLAYHVMSVQGIKGVEFGLGFEAARLPGSLVHDDIYY
KENEGFYRKTNNAGGIEGGMSNGNPIVIRAAMKPIPTLLRPLDSVDIATKEETKAIYERSDVTAVEAAACVLEAVCAWVI
ADECLKKFGGDSVEELKRNYDTYLAYVRSF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=348, Percent_Identity=34.7701149425287, Blast_Score=148, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6321290, Length=363, Percent_Identity=32.5068870523416, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_THETN (Q8R9A6)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623307.1
- HSSP:   O66493
- ProteinModelPortal:   Q8R9A6
- SMR:   Q8R9A6
- GeneID:   996683
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1711
- NMPDR:   fig|273068.3.peg.1690
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   TTEN273068:TTE1711-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38674; Mature: 38674

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGEALIAIIEGLPSNLFIDAEFINKELERRQKGYGRGGRMAIEKDEIHIIS
CCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEE
GVRDGKTTGAPLAMEIKNRDYKNWKDKKVPPVTRPRPGHADLPGSIKYNQRDIRNILERA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SARETAARVAVGSVAKLLLKELNISLKSRVLEIGGAKREEKWKRLIEKAKKEGDTLGGII
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
EIVIEGVPVGLGSHAQWDRKLDALLAYHVMSVQGIKGVEFGLGFEAARLPGSLVHDDIYY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHCCCEE
KENEGFYRKTNNAGGIEGGMSNGNPIVIRAAMKPIPTLLRPLDSVDIATKEETKAIYERS
ECCCCCEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
DVTAVEAAACVLEAVCAWVIADECLKKFGGDSVEELKRNYDTYLAYVRSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGEALIAIIEGLPSNLFIDAEFINKELERRQKGYGRGGRMAIEKDEIHIIS
CCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEE
GVRDGKTTGAPLAMEIKNRDYKNWKDKKVPPVTRPRPGHADLPGSIKYNQRDIRNILERA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SARETAARVAVGSVAKLLLKELNISLKSRVLEIGGAKREEKWKRLIEKAKKEGDTLGGII
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
EIVIEGVPVGLGSHAQWDRKLDALLAYHVMSVQGIKGVEFGLGFEAARLPGSLVHDDIYY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHCCCEE
KENEGFYRKTNNAGGIEGGMSNGNPIVIRAAMKPIPTLLRPLDSVDIATKEETKAIYERS
ECCCCCEEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
DVTAVEAAACVLEAVCAWVIADECLKKFGGDSVEELKRNYDTYLAYVRSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336