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The map label for this gene is engD [H]

Identifier: 20808085

GI number: 20808085

Start: 1609461

End: 1610552

Strand: Direct

Name: engD [H]

Synonym: TTE1658

Alternate gene names: 20808085

Gene position: 1609461-1610552 (Clockwise)

Preceding gene: 20808042

Following gene: 20808102

Centisome position: 59.84

GC content: 38.0

Gene sequence:

>1092_bases
ATGGAAATAGGAATTGTTGGTCTACCAAATGTAGGAAAGAGCACACTTTTTAACGCAATAACCAAAGCTGGTGCAGAATG
CGCCAATTATCCTTTTTGCACTATTGAGCCAAATGTAGGGATTGTATCTGTCCCCGATGAAAGATTGGATTTTCTTGCTA
AAATTGAAAATCCTCAAAAAGTAGTTCCTGCCACCATAAAATTTGTGGACATTGCAGGCCTTGTAAAAGGCGCAAGCAAA
GGAGAAGGTTTAGGAAATAAATTTTTATCTCATATAAGAGAAGTAGACGCAATTTTAAACGTTGTGAGATGCTTTGAAGA
CAGCAATATAGTGCATGTGGAAGGGTCTATTGACCCCGTAAGAGATGTCGAGATTATAAACCTGGAGCTCATACTGGCTG
ATTTAGAGACTGTAGAAAGGCGAATGCAAAAAACTTCAAAACTTGCTAGAAACGATAAAAAAGCCGCCTTTGAACTTGAA
GTTTTGGAAAAAATAAAAAATACACTGGAAGAGGGAAAGCCTGCAAGGGCAGTTCAATTTGATGAAGAAGAAAAAGCCGT
AGTAAATCAGCTGATGCTTTTAACTTCAAAGCCTGTGATGTATGTGGCAAATATATCAGAAGAAGATTTAATCTTAAGAG
AAGAAAATCTACACGTAAAAAAGCTAAGAGAATATGCATTAAAAGAAGGCTCAGAAGTTTTAGTAATAAGCGCAAAAATT
GAAGAAGAGCTAGCAGCTCTTCCAGATGAAGAAAGAAATGAGCTTTTAAAAGAATACGGGCTCAAAGAGCCCGGGCTTAA
CAATATAATAAGGCACGGATATTCTCTTTTAGGACTAATTACATTTTTCACTGCAGGGCCTAAAGAAGTACATGCCTGGA
CAATAAAAAGGGGAACTAAAGCTCCTCAAGCGGCTGGGAAAATCCACTCTGACTTTGAAAGAGGGTTTATAAGAGCAGAA
GTAATCTCCTTTGAAGATTTAGTCAAAGCAGGATCACAGGCAGCAGCAAGAGAAATGGGGCTTTTAAGGCTTGAAGGCAA
AGACTATGTCATGCAGGATGGAGATGTTGTAGTATTTAGATTTAACGTGTAA

Upstream 100 bases:

>100_bases
AAAGTATTATGCTAAATTATGGAAAAGCATTAAAAACATTTGAAAAATTTTTATGAGTAATATATAATCCATATGTGTAT
AATTAATGGAGGGAGAATAA

Downstream 100 bases:

>100_bases
TCTACTCCAGGCTTATTTCCACATGTTCTCCATCCTCTTTATCGTATACATCCACGATTTTTCCTGTTTCTCCTTCTTCT
ATAGCTTTTAAAAGGTCATT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVSVPDERLDFLAKIENPQKVVPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPVRDVEIINLELILADLETVERRMQKTSKLARNDKKAAFELE
VLEKIKNTLEEGKPARAVQFDEEEKAVVNQLMLLTSKPVMYVANISEEDLILREENLHVKKLREYALKEGSEVLVISAKI
EEELAALPDEERNELLKEYGLKEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKRGTKAPQAAGKIHSDFERGFIRAE
VISFEDLVKAGSQAAAREMGLLRLEGKDYVMQDGDVVVFRFNV

Sequences:

>Translated_363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVSVPDERLDFLAKIENPQKVVPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPVRDVEIINLELILADLETVERRMQKTSKLARNDKKAAFELE
VLEKIKNTLEEGKPARAVQFDEEEKAVVNQLMLLTSKPVMYVANISEEDLILREENLHVKKLREYALKEGSEVLVISAKI
EEELAALPDEERNELLKEYGLKEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKRGTKAPQAAGKIHSDFERGFIRAE
VISFEDLVKAGSQAAAREMGLLRLEGKDYVMQDGDVVVFRFNV
>Mature_363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVSVPDERLDFLAKIENPQKVVPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPVRDVEIINLELILADLETVERRMQKTSKLARNDKKAAFELE
VLEKIKNTLEEGKPARAVQFDEEEKAVVNQLMLLTSKPVMYVANISEEDLILREENLHVKKLREYALKEGSEVLVISAKI
EEELAALPDEERNELLKEYGLKEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKRGTKAPQAAGKIHSDFERGFIRAE
VISFEDLVKAGSQAAAREMGLLRLEGKDYVMQDGDVVVFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=47.9674796747967, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI58761502, Length=216, Percent_Identity=43.0555555555556, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI24308117, Length=99, Percent_Identity=38.3838383838384, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=57.967032967033, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=143, Percent_Identity=32.8671328671329, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=45.6284153005465, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17552324, Length=191, Percent_Identity=27.7486910994764, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=44.8648648648649, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=39.3139841688654, Blast_Score=255, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6321649, Length=350, Percent_Identity=27.4285714285714, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321962, Length=149, Percent_Identity=27.5167785234899, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=47.554347826087, Blast_Score=329, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=47.554347826087, Blast_Score=329, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=47.554347826087, Blast_Score=329, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=46.177370030581, Blast_Score=274, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24585318, Length=190, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129375, Length=113, Percent_Identity=31.858407079646, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40307; Mature: 40307

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVSVPDERLDFLAKIENPQK
CCEEEEECCCCCHHHHHHHHHHHCHHHCCCCEEEECCCCCEEECCHHHHHHHHHCCCCCH
VVPATIKFVDIAGLVKGASKGEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPV
HCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
RDVEIINLELILADLETVERRMQKTSKLARNDKKAAFELEVLEKIKNTLEEGKPARAVQF
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECC
DEEEKAVVNQLMLLTSKPVMYVANISEEDLILREENLHVKKLREYALKEGSEVLVISAKI
CCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEECH
EEELAALPDEERNELLKEYGLKEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKRGTK
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
APQAAGKIHSDFERGFIRAEVISFEDLVKAGSQAAAREMGLLRLEGKDYVMQDGDVVVFR
CCHHHHHHHHHHHHCCHHHHHHCHHHHHHCCCHHHHHHCCEEEECCCCEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVSVPDERLDFLAKIENPQK
CCEEEEECCCCCHHHHHHHHHHHCHHHCCCCEEEECCCCCEEECCHHHHHHHHHCCCCCH
VVPATIKFVDIAGLVKGASKGEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPV
HCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
RDVEIINLELILADLETVERRMQKTSKLARNDKKAAFELEVLEKIKNTLEEGKPARAVQF
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECC
DEEEKAVVNQLMLLTSKPVMYVANISEEDLILREENLHVKKLREYALKEGSEVLVISAKI
CCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEECH
EEELAALPDEERNELLKEYGLKEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKRGTK
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
APQAAGKIHSDFERGFIRAEVISFEDLVKAGSQAAAREMGLLRLEGKDYVMQDGDVVVFR
CCHHHHHHHHHHHHCCHHHHHHCHHHHHHCCCHHHHHHCCEEEECCCCEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]