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The map label for this gene is PqqL2 [H]

Identifier: 20808082

GI number: 20808082

Start: 1606118

End: 1607392

Strand: Reverse

Name: PqqL2 [H]

Synonym: TTE1655

Alternate gene names: 20808082

Gene position: 1607392-1606118 (Counterclockwise)

Preceding gene: 20808083

Following gene: 20808081

Centisome position: 59.77

GC content: 36.86

Gene sequence:

>1275_bases
GTGCAGCAGGTTTATGATGAAAAGGTCAGAGAGAAGATTTTGTTTGAAGAGCTTGAAAATGGACTTAAAGTTTATGTGAT
GCCTAAGAAAGGATATACAAAGCAGTTTGCTATATTTGCAACTCGATTTGGGTCAAATGACAGCAAGTTTATCGCACCGG
GCGATGATTATGTTACAGAAGTTCCTGATGGCGTGGCCCATTTTCTTGAACATAAAATGTTTGAGGAAGAAGAAGGCAGC
ATTTTTGAGAAGTTCTCTCAACTTGGGGCATCTGCGAATGCCTATACGAATTTTACTACTACTGCCTATCTGTTTTCTAG
TACAGAAAATTTTTATGAAAATTTAAAGCTTTTGGTCCATTTTGTGCAAAATCCTTATTTTACGGATGAAAATGTGGAAA
AAGAAAAGGGGATTATAGCCCAGGAGATAAGGATGTATCAGGATGACCCAAACTGGAGAGTGTATTTTAACGCCTTGGAA
GCTTTATATCACGTCTATCCTGTGAAAAAGGACATAGCAGGGACTATTGAGTCCATCTCAAGAATTGACAAAGATATTTT
GTACAAATGCTATTACACCTTTTATCATCCTGAAAATATGGTCTTATTTGCTGTAGGGGATATTGATGTTGACAAGACTC
TTCAGGTTATAGAGGAAAATGTAAGGCAAGTTAAAAAACAAGGTGAAATAAAGAGGATTTACCCAGATGAACCTGTAGAA
GTTCACAAAAAAGAAGTAGTTCAGAATATGCAGGTTTCTATTCCTCTTTTCAATTTGGCGTTCAAGGACACAGATGTGGG
CTTTGGCGGAAGGAATTTATTGAAAAAGAGTTTGGAAGTGCAGATAGGATTAGAAATGGCTGTCGGCAGGAGTTCTGAAC
TTTATGAAAAACTCTATCAGGAAGGTCTTGTGGATAGCACTTTTGGCTTTGATTACACGGGGGAGATAGATTATGGATAC
ACTATAATAGGTGGGCAGTCAAAAGACCCGCTCAAAGTTAGGGATATTATTATTAAGGCTTTTAAAGAAAAAAGCTTTTT
GGACAGGGAGACTTTTGAGAGAATAAAGAGGAAGTACATTGGAAAATTTCTCAGGACTTTTAATTCGGTGGAAAGCATAG
CCTATAGTTTTATAAACCTGTACATGAAAGACATAGATTTGATGGATTATTTACCGGTTTTACATCAGATAAACTTCAAG
GATGTAGCAGAGAGGGTTGAAAGCCATTTAAATGAAGAAACTAGTGCGATGTCTATCATATACCCTGTTAAATAG

Upstream 100 bases:

>100_bases
GAAAATAGAGAAAGTCAGTAAAGAAGACGTAGTAGAAGTATCTAAAAAAGTGAAATTGGATACGGTTTACTTCATGAGGA
ATAAAAAGGAGGCATAAACA

Downstream 100 bases:

>100_bases
GTCTTTGGACCTTCTAGGTCTAAAGACCTGTTTTTTTATTTTTTTATAAAATTTTAGCAGGATTTTTTGATTTTATATAG
AATAACATATTAAGTGGTGA

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MQQVYDEKVREKILFEELENGLKVYVMPKKGYTKQFAIFATRFGSNDSKFIAPGDDYVTEVPDGVAHFLEHKMFEEEEGS
IFEKFSQLGASANAYTNFTTTAYLFSSTENFYENLKLLVHFVQNPYFTDENVEKEKGIIAQEIRMYQDDPNWRVYFNALE
ALYHVYPVKKDIAGTIESISRIDKDILYKCYYTFYHPENMVLFAVGDIDVDKTLQVIEENVRQVKKQGEIKRIYPDEPVE
VHKKEVVQNMQVSIPLFNLAFKDTDVGFGGRNLLKKSLEVQIGLEMAVGRSSELYEKLYQEGLVDSTFGFDYTGEIDYGY
TIIGGQSKDPLKVRDIIIKAFKEKSFLDRETFERIKRKYIGKFLRTFNSVESIAYSFINLYMKDIDLMDYLPVLHQINFK
DVAERVESHLNEETSAMSIIYPVK

Sequences:

>Translated_424_residues
MQQVYDEKVREKILFEELENGLKVYVMPKKGYTKQFAIFATRFGSNDSKFIAPGDDYVTEVPDGVAHFLEHKMFEEEEGS
IFEKFSQLGASANAYTNFTTTAYLFSSTENFYENLKLLVHFVQNPYFTDENVEKEKGIIAQEIRMYQDDPNWRVYFNALE
ALYHVYPVKKDIAGTIESISRIDKDILYKCYYTFYHPENMVLFAVGDIDVDKTLQVIEENVRQVKKQGEIKRIYPDEPVE
VHKKEVVQNMQVSIPLFNLAFKDTDVGFGGRNLLKKSLEVQIGLEMAVGRSSELYEKLYQEGLVDSTFGFDYTGEIDYGY
TIIGGQSKDPLKVRDIIIKAFKEKSFLDRETFERIKRKYIGKFLRTFNSVESIAYSFINLYMKDIDLMDYLPVLHQINFK
DVAERVESHLNEETSAMSIIYPVK
>Mature_424_residues
MQQVYDEKVREKILFEELENGLKVYVMPKKGYTKQFAIFATRFGSNDSKFIAPGDDYVTEVPDGVAHFLEHKMFEEEEGS
IFEKFSQLGASANAYTNFTTTAYLFSSTENFYENLKLLVHFVQNPYFTDENVEKEKGIIAQEIRMYQDDPNWRVYFNALE
ALYHVYPVKKDIAGTIESISRIDKDILYKCYYTFYHPENMVLFAVGDIDVDKTLQVIEENVRQVKKQGEIKRIYPDEPVE
VHKKEVVQNMQVSIPLFNLAFKDTDVGFGGRNLLKKSLEVQIGLEMAVGRSSELYEKLYQEGLVDSTFGFDYTGEIDYGY
TIIGGQSKDPLKVRDIIIKAFKEKSFLDRETFERIKRKYIGKFLRTFNSVESIAYSFINLYMKDIDLMDYLPVLHQINFK
DVAERVESHLNEETSAMSIIYPVK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=229, Percent_Identity=27.5109170305677, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787770, Length=239, Percent_Identity=24.6861924686192, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=233, Percent_Identity=27.8969957081545, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49357; Mature: 49357

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQVYDEKVREKILFEELENGLKVYVMPKKGYTKQFAIFATRFGSNDSKFIAPGDDYVTE
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCCCEECCCCCHHHH
VPDGVAHFLEHKMFEEEEGSIFEKFSQLGASANAYTNFTTTAYLFSSTENFYENLKLLVH
CCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHH
FVQNPYFTDENVEKEKGIIAQEIRMYQDDPNWRVYFNALEALYHVYPVKKDIAGTIESIS
HHHCCCCCCCCCCHHHCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHH
RIDKDILYKCYYTFYHPENMVLFAVGDIDVDKTLQVIEENVRQVKKQGEIKRIYPDEPVE
HHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHH
VHKKEVVQNMQVSIPLFNLAFKDTDVGFGGRNLLKKSLEVQIGLEMAVGRSSELYEKLYQ
HHHHHHHHHHEEECEEEEEEEECCCCCCCHHHHHHHHHHHEEEEHHHCCCCHHHHHHHHH
EGLVDSTFGFDYTGEIDYGYTIIGGQSKDPLKVRDIIIKAFKEKSFLDRETFERIKRKYI
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GKFLRTFNSVESIAYSFINLYMKDIDLMDYLPVLHQINFKDVAERVESHLNEETSAMSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEE
YPVK
EECC
>Mature Secondary Structure
MQQVYDEKVREKILFEELENGLKVYVMPKKGYTKQFAIFATRFGSNDSKFIAPGDDYVTE
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCCCEECCCCCHHHH
VPDGVAHFLEHKMFEEEEGSIFEKFSQLGASANAYTNFTTTAYLFSSTENFYENLKLLVH
CCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHH
FVQNPYFTDENVEKEKGIIAQEIRMYQDDPNWRVYFNALEALYHVYPVKKDIAGTIESIS
HHHCCCCCCCCCCHHHCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHH
RIDKDILYKCYYTFYHPENMVLFAVGDIDVDKTLQVIEENVRQVKKQGEIKRIYPDEPVE
HHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHH
VHKKEVVQNMQVSIPLFNLAFKDTDVGFGGRNLLKKSLEVQIGLEMAVGRSSELYEKLYQ
HHHHHHHHHHEEECEEEEEEEECCCCCCCHHHHHHHHHHHEEEEHHHCCCCHHHHHHHHH
EGLVDSTFGFDYTGEIDYGYTIIGGQSKDPLKVRDIIIKAFKEKSFLDRETFERIKRKYI
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GKFLRTFNSVESIAYSFINLYMKDIDLMDYLPVLHQINFKDVAERVESHLNEETSAMSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEE
YPVK
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]