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The map label for this gene is HypE2 [C]

Identifier: 20807973

GI number: 20807973

Start: 1498946

End: 1499947

Strand: Direct

Name: HypE2 [C]

Synonym: TTE1537

Alternate gene names: 20807973

Gene position: 1498946-1499947 (Clockwise)

Preceding gene: 20807964

Following gene: 20807984

Centisome position: 55.73

GC content: 37.13

Gene sequence:

>1002_bases
ATGAAGCTAGAAATAGGGAAAATTCCTGTAGAAGTGATGAAAAGGTCCATTTTCCCTTATCTTGGCACAAAAAGAAAAGA
AGTCTTAGTTCACTCCCAGTTAGGAGAAGACTCCAGCATAATCGATTTTGGTGAATACGTAGCAGTTCTTTCCACAGACC
CAATTACAGCAGCAGATAAATTGAGCGGCTTTTTATCTGTCATAATATCCTGCAATGACCTTGCAGCCTGCGGCGCAGAA
CCTATTGGCATACTCACCACAATACTTCTTCCAGAGGGCACAGAGGAACAAATGCTTAAAAATATAATGCAGGAAATTGA
CAAAGCTTCTAAAATGATAGGAATTGAAGTTTTAGGAGGGCATACTGAAGTAACTCAAGCAGTAAATAAACCTGTAATAA
GCACAACAGCAATTGGAATTGCTAGAAAAGGAAAATACATAACCTCAAAAGGGGCTAAAATAGGAGATGACGTAATTGTA
ACAAAAGCTTTGGGACTTGAAGGAACAGCAATTTTGGCAACAGATTATGAGGATTTGCTCATCAAACATTTCGGGAAAGA
CTTTGTCTTAAAAGCACAAAGCTTTATAAACGAAATAAGCGTAATAGAGGAGGGTCTAATAGCTTCCCAAAATGGCGCAA
ATGCCATGCATGATATAACAGAAGGAGGAGTGCTAGGAGCAACTTATGAAATTTCCGAAGCATCAGGATTAGGGATTGAA
ATATACGAAGAAAAATTGCCTTTTCGACGTGAGACAAAGGAAATATGCAAATTTTTTGGATTAAATCCTTTAAAATTGAT
ATCCAGCGGTTCCATGCTGATTACTGCAGAAGATGGAAACAGAATAGTCAAAGCCTTATCTGAAAAAGGAATACAAGCTA
CAATAATAGGAAAAATTGTGAAAGAAGGAAGGTATTTGATAACTTCTTCCGGAAAAGAAAAAATTCTTCCACCTGAAAAA
GACGAAATATACAGAGCAGATAAAGGCAGGGCAAAAAATTAA

Upstream 100 bases:

>100_bases
CATTCTCTTCAAGTTGTCCATAGGGAATATTTAAAAAAAGCAAAAATGTGGTAATATGAAATTGTTCGCTCTAAATATCA
AGAAAAAAGGATGTGACAAA

Downstream 100 bases:

>100_bases
TCCCTGTCTTTCTCTGCCCTTAAAATTTCGAGCAATCTTGTAAAATAATCGGGCAAAGGGGCTTCAAATTCCATGTACAC
TCCTTTTGTCGGATGAATAA

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKLEIGKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVLSTDPITAADKLSGFLSVIISCNDLAACGAE
PIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEVTQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIV
TKALGLEGTAILATDYEDLLIKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIE
IYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITAEDGNRIVKALSEKGIQATIIGKIVKEGRYLITSSGKEKILPPEK
DEIYRADKGRAKN

Sequences:

>Translated_333_residues
MKLEIGKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVLSTDPITAADKLSGFLSVIISCNDLAACGAE
PIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEVTQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIV
TKALGLEGTAILATDYEDLLIKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIE
IYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITAEDGNRIVKALSEKGIQATIIGKIVKEGRYLITSSGKEKILPPEK
DEIYRADKGRAKN
>Mature_333_residues
MKLEIGKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVLSTDPITAADKLSGFLSVIISCNDLAACGAE
PIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEVTQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIV
TKALGLEGTAILATDYEDLLIKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIE
IYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITAEDGNRIVKALSEKGIQATIIGKIVKEGRYLITSSGKEKILPPEK
DEIYRADKGRAKN

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=285, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35957; Mature: 35957

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEIGKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVLSTDPITAADK
CCCCCCCCCHHHHHHHHHHHCCCCHHHEEEEHHCCCCCCEEEHHHEEEEEECCCCCHHHH
LSGFLSVIISCNDLAACGAEPIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGG
HHHHHHHHHCCCCHHHCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECC
HTEVTQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDLL
CHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCEEEECCHHHHH
IKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIE
HHHCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCCCEEEEEEEECCCCCCCEE
IYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITAEDGNRIVKALSEKGIQATIIGKIV
EEHHCCCCHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCEEHHHHHHH
KEGRYLITSSGKEKILPPEKDEIYRADKGRAKN
HCCCEEEECCCCCCCCCCCHHHHEECCCCCCCC
>Mature Secondary Structure
MKLEIGKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVLSTDPITAADK
CCCCCCCCCHHHHHHHHHHHCCCCHHHEEEEHHCCCCCCEEEHHHEEEEEECCCCCHHHH
LSGFLSVIISCNDLAACGAEPIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGG
HHHHHHHHHCCCCHHHCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECC
HTEVTQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDLL
CHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCEEEECCHHHHH
IKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIE
HHHCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHCCCCEEEEEEEECCCCCCCEE
IYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITAEDGNRIVKALSEKGIQATIIGKIV
EEHHCCCCHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCHHHHHHHHHCCCEEHHHHHHH
KEGRYLITSSGKEKILPPEKDEIYRADKGRAKN
HCCCEEEECCCCCCCCCCCHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]