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The map label for this gene is coaD

Identifier: 20807930

GI number: 20807930

Start: 1455532

End: 1456014

Strand: Reverse

Name: coaD

Synonym: TTE1486

Alternate gene names: 20807930

Gene position: 1456014-1455532 (Counterclockwise)

Preceding gene: 20807931

Following gene: 20807929

Centisome position: 54.14

GC content: 35.82

Gene sequence:

>483_bases
ATGAGAGTAGCGATTTATCCAGGAAGTTTTGATCCGGTAACTTATGGGCATATTGACATAATAAAAAGAGGTGCAAATCT
TTTTGACAAGCTGATTGTAGCTGTTTTATTAAATCCTGCTAAAAGACCTTTATTTTCTATTCAAGAAAGAATAGAGCTTC
TGAAAGAAGTGACCAAGGATATTCCCAATGTTGAAGTAGATTATTTTGACGGATTGCTGGTAGAATACGCTAAAAAAGTT
AATGCCAGTGCAATAATAAAGGGGCTCAGAATGGTTTCTGATTTTGAATACGAGTTTCAAATGGCTCTTGTAAATAAAAA
GCTAAATCCGTCAGTTGAGACAATCTTCTTAATGACCAGTCCAAAATACGGGTATCTAAGTTCTAGCCTTGTCAAGGAAA
TTGCTCAATTTGGCGGATGCCTTTCCGAGTTTGTACCTGATATTGTGGCAGAAAGGCTCATGGAAAAGTTTAAGAAAAGT
TAA

Upstream 100 bases:

>100_bases
TTCATAAAAGAGATGAGTTAAAAGAAAGATATGGAAAGCTTAAAAAAGTAAGAGAAAATAAATACGGAGAGACAATACTG
ATGTTTTATGAGGAGGTAGT

Downstream 100 bases:

>100_bases
AGGGGGTTTTATTTTTGTCAAATTTTGAAGGACTGGAAGTGCTGAGCCTTTTAGAAGAACTGGAGGATATCATAGAGAAC
AGTTCTTCAATACCGCTTTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRVAIYPGSFDPVTYGHIDIIKRGANLFDKLIVAVLLNPAKRPLFSIQERIELLKEVTKDIPNVEVDYFDGLLVEYAKKV
NASAIIKGLRMVSDFEYEFQMALVNKKLNPSVETIFLMTSPKYGYLSSSLVKEIAQFGGCLSEFVPDIVAERLMEKFKKS

Sequences:

>Translated_160_residues
MRVAIYPGSFDPVTYGHIDIIKRGANLFDKLIVAVLLNPAKRPLFSIQERIELLKEVTKDIPNVEVDYFDGLLVEYAKKV
NASAIIKGLRMVSDFEYEFQMALVNKKLNPSVETIFLMTSPKYGYLSSSLVKEIAQFGGCLSEFVPDIVAERLMEKFKKS
>Mature_160_residues
MRVAIYPGSFDPVTYGHIDIIKRGANLFDKLIVAVLLNPAKRPLFSIQERIELLKEVTKDIPNVEVDYFDGLLVEYAKKV
NASAIIKGLRMVSDFEYEFQMALVNKKLNPSVETIFLMTSPKYGYLSSSLVKEIAQFGGCLSEFVPDIVAERLMEKFKKS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=45.4545454545455, Blast_Score=166, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_THETN (Q8R9U9)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623101.1
- ProteinModelPortal:   Q8R9U9
- SMR:   Q8R9U9
- GeneID:   997565
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1486
- NMPDR:   fig|273068.3.peg.1448
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   TTEN273068:TTE1486-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18116; Mature: 18116

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIYPGSFDPVTYGHIDIIKRGANLFDKLIVAVLLNPAKRPLFSIQERIELLKEVTKD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IPNVEVDYFDGLLVEYAKKVNASAIIKGLRMVSDFEYEFQMALVNKKLNPSVETIFLMTS
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
PKYGYLSSSLVKEIAQFGGCLSEFVPDIVAERLMEKFKKS
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVAIYPGSFDPVTYGHIDIIKRGANLFDKLIVAVLLNPAKRPLFSIQERIELLKEVTKD
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IPNVEVDYFDGLLVEYAKKVNASAIIKGLRMVSDFEYEFQMALVNKKLNPSVETIFLMTS
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
PKYGYLSSSLVKEIAQFGGCLSEFVPDIVAERLMEKFKKS
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336