Click here to switch to the map view.

The map label for this gene is ackA [H]

Identifier: 20807925

GI number: 20807925

Start: 1450296

End: 1451501

Strand: Reverse

Name: ackA [H]

Synonym: TTE1481

Alternate gene names: 20807925

Gene position: 1451501-1450296 (Counterclockwise)

Preceding gene: 20807926

Following gene: 20807924

Centisome position: 53.97

GC content: 40.71

Gene sequence:

>1206_bases
ATGAAAATTTTGGTTATGAATTGTGGCAGTTCTTCTTTAAAATATCAACTACTTGATATGGAAAACAACAAGGTTTTGGC
AAAGGGGTTGGCGGAAAGAATAGGAATAAATGACTCTTTATTGACCCATCAGGCGGAAGGCAAGGAAAAAGTGAAGATAC
AGAGGGATATGAAAAATCACAAGGAAGCTATACAGTTAGTTTTGGAAGTTTTAGTGGATAAAGAAATAGGTGTTATAAAG
GACATGAAGGAAATAGATGCGGTGGGACACAGGGTTGTCCACGGAGGAGAATATTTTACAGATTCTGTATTGATTGATGA
TGAAGTGATAAAGAAATTAGAAGACTGTATTGACCTTGCACCTTTACACAATCCTGCCAACATTGAAGGGATAAAAGCGT
GTCAGCAGATAATGCCAGGAGTACCCATGGTGGCAGTTTTTGATACGGCTTTCCATCAGACAATGCCGGATTATGCCTAC
ATATATCCAATTCCCTATGAGTATTACGAAAAGCACAGAATAAGAAGGTATGGCTTCCACGGGACTTCCCACAAGTACGT
CTCAATGAGAGCAGCAGAGATTCTCGGAAGGCCAATTGAAGAATTGAAAATTGTCACCTGCCATCTGGGGAATGGGGCAA
GCATTACAGCGGTTAAAAACGGCAAATCGATTGACACCAGCATGGGATTTACCCCTTTAGAAGGATTGGCAATGGGTACC
AGGTCAGGAAGCATTGACCCCTCAATTGTGACATTTTTAATGGAAAAAGAAGGCCTTACCGCTCATCAGGTAGTTGATAT
CTTGAACAAAAAATCAGGTGTTTACGGGATTTCAGGCATCAGCAATGATTTTAGAGATATAGAAAATGCAGCATTTAATG
AGGGAAATAAGAGGGCAATGCTGGCACTAAAGGTATTTGCCTACATTGCTAAAAAGACCATAGGAGCCTATGCCGCTGCT
ATGGGAGGAGTGGATGCCATTGTATTTACTGCTGGAGTTGGAGAAAATGGACCTGAGATGAGAGAATTTATTCTGGAAGG
CCTGGAGTTTTTAGGATTTACGCTTGACAAGGAGAAAAACAGGGTGAGAGGGAAAGAGGCAATAATATCTACAGAAGATT
CCAGAGTAAAAGTCATGGTAATTCCTACAAATGAGGAGTACATGATAGCGAAAGATACTGAGAAATTGGTGAAGGGGATT
AAGTAG

Upstream 100 bases:

>100_bases
TGATTTGTCAAGGGGATGCAGCGTAGAAGATATTGTAAATGTTATAGCGATAACGAGTGTACAAGCTCAAGGAATAGTGT
AAAAAGGGGAGGCAATAATT

Downstream 100 bases:

>100_bases
ATATTGACAATTGGTATAGGGGTTAGTATAATAGGTGTTGTCAATTACGTTAAGGTGTGTGAAGAAAAATGAAAATTGAC
CTTTTGAAAATCAAAGGGCA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKILVMNCGSSSLKYQLLDMENNKVLAKGLAERIGINDSLLTHQAEGKEKVKIQRDMKNHKEAIQLVLEVLVDKEIGVIK
DMKEIDAVGHRVVHGGEYFTDSVLIDDEVIKKLEDCIDLAPLHNPANIEGIKACQQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKHRIRRYGFHGTSHKYVSMRAAEILGRPIEELKIVTCHLGNGASITAVKNGKSIDTSMGFTPLEGLAMGT
RSGSIDPSIVTFLMEKEGLTAHQVVDILNKKSGVYGISGISNDFRDIENAAFNEGNKRAMLALKVFAYIAKKTIGAYAAA
MGGVDAIVFTAGVGENGPEMREFILEGLEFLGFTLDKEKNRVRGKEAIISTEDSRVKVMVIPTNEEYMIAKDTEKLVKGI
K

Sequences:

>Translated_401_residues
MKILVMNCGSSSLKYQLLDMENNKVLAKGLAERIGINDSLLTHQAEGKEKVKIQRDMKNHKEAIQLVLEVLVDKEIGVIK
DMKEIDAVGHRVVHGGEYFTDSVLIDDEVIKKLEDCIDLAPLHNPANIEGIKACQQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKHRIRRYGFHGTSHKYVSMRAAEILGRPIEELKIVTCHLGNGASITAVKNGKSIDTSMGFTPLEGLAMGT
RSGSIDPSIVTFLMEKEGLTAHQVVDILNKKSGVYGISGISNDFRDIENAAFNEGNKRAMLALKVFAYIAKKTIGAYAAA
MGGVDAIVFTAGVGENGPEMREFILEGLEFLGFTLDKEKNRVRGKEAIISTEDSRVKVMVIPTNEEYMIAKDTEKLVKGI
K
>Mature_401_residues
MKILVMNCGSSSLKYQLLDMENNKVLAKGLAERIGINDSLLTHQAEGKEKVKIQRDMKNHKEAIQLVLEVLVDKEIGVIK
DMKEIDAVGHRVVHGGEYFTDSVLIDDEVIKKLEDCIDLAPLHNPANIEGIKACQQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKHRIRRYGFHGTSHKYVSMRAAEILGRPIEELKIVTCHLGNGASITAVKNGKSIDTSMGFTPLEGLAMGT
RSGSIDPSIVTFLMEKEGLTAHQVVDILNKKSGVYGISGISNDFRDIENAAFNEGNKRAMLALKVFAYIAKKTIGAYAAA
MGGVDAIVFTAGVGENGPEMREFILEGLEFLGFTLDKEKNRVRGKEAIISTEDSRVKVMVIPTNEEYMIAKDTEKLVKGI
K

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=45.1371571072319, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI145693184, Length=398, Percent_Identity=43.9698492462312, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44362; Mature: 44362

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVMNCGSSSLKYQLLDMENNKVLAKGLAERIGINDSLLTHQAEGKEKVKIQRDMKNH
CEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
KEAIQLVLEVLVDKEIGVIKDMKEIDAVGHRVVHGGEYFTDSVLIDDEVIKKLEDCIDLA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCEEECCEEECHHHHHHHHHHHHHC
PLHNPANIEGIKACQQIMPGVPMVAVFDTAFHQTMPDYAYIYPIPYEYYEKHRIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCC
GTSHKYVSMRAAEILGRPIEELKIVTCHLGNGASITAVKNGKSIDTSMGFTPLEGLAMGT
CCCCHHHHHHHHHHHCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHEECC
RSGSIDPSIVTFLMEKEGLTAHQVVDILNKKSGVYGISGISNDFRDIENAAFNEGNKRAM
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCHHH
LALKVFAYIAKKTIGAYAAAMGGVDAIVFTAGVGENGPEMREFILEGLEFLGFTLDKEKN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHH
RVRGKEAIISTEDSRVKVMVIPTNEEYMIAKDTEKLVKGIK
HHCCCHHEEECCCCEEEEEEEECCCCEEEECCHHHHHCCCC
>Mature Secondary Structure
MKILVMNCGSSSLKYQLLDMENNKVLAKGLAERIGINDSLLTHQAEGKEKVKIQRDMKNH
CEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
KEAIQLVLEVLVDKEIGVIKDMKEIDAVGHRVVHGGEYFTDSVLIDDEVIKKLEDCIDLA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCEEECCEEECHHHHHHHHHHHHHC
PLHNPANIEGIKACQQIMPGVPMVAVFDTAFHQTMPDYAYIYPIPYEYYEKHRIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCC
GTSHKYVSMRAAEILGRPIEELKIVTCHLGNGASITAVKNGKSIDTSMGFTPLEGLAMGT
CCCCHHHHHHHHHHHCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHEECC
RSGSIDPSIVTFLMEKEGLTAHQVVDILNKKSGVYGISGISNDFRDIENAAFNEGNKRAM
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCHHH
LALKVFAYIAKKTIGAYAAAMGGVDAIVFTAGVGENGPEMREFILEGLEFLGFTLDKEKN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHH
RVRGKEAIISTEDSRVKVMVIPTNEEYMIAKDTEKLVKGIK
HHCCCHHEEECCCCEEEEEEEECCCCEEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA