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The map label for this gene is codY

Identifier: 20807893

GI number: 20807893

Start: 1420226

End: 1420978

Strand: Reverse

Name: codY

Synonym: TTE1446

Alternate gene names: 20807893

Gene position: 1420978-1420226 (Counterclockwise)

Preceding gene: 20807894

Following gene: 20807892

Centisome position: 52.84

GC content: 38.91

Gene sequence:

>753_bases
ATGACGCTTTTAGAAAAAACGAGAAAATTAAATCGAATCTTACAAAAGACTGGCATACAACCGGTAGACTTTATGGAAAT
GGCTTCTATTTTAAAAGAAGTAATTGAAGCCAATGTCTATATCTTAAGTAGAAAAGGGAAAGTTCTAGGGTATAGCGCTT
TAAAGGACTATGGAGATGAAATTTTTGCGAAAGACAAGGCAATTCCTGAGGAGTACAACGACAGACTTTTAAGAGTTACA
GAAACGCTAGCAAATGACAAAGGAAAGCTCTTTAAAGAAGAGAAGGCCCTAGCTGACTTGATAGTGACAGTTGTCCCTAT
AAATGGAGGAGGAGATAGACTAGGTACTTTGCTTCTTATAAGATCCACGAAAGAATTTACTGACGACGATTTGATAATTG
CAGAGTACGGAGCTACAGTGGTAGGCCTTGAGATTTTAAGAGCAAAGAATGAAGAAATTGAAGAAGAGGCACGGAAAAGG
GCTGTAGTGCAGATGGCTTTAGCTACTCTCTCCTATTCAGAGCTTCAAGCTATAAAGAACATATTTGAGGAATTGAAAGG
GAAAGAGGGACTTCTTGTTGCCAGCAAGATAGCTGACAAAGTAGGCATTACAAGGTCTGTAATTGTAAATGCTTTGAGAA
AGTTTGAAAGCGCTGGAATAATTGAGTCCCGTTCCTTGGGCATGAAGGGGACTCATATAAGGGTTCTCAATGAAAAGCTC
CTGGAAGAGCTTGAAAAAATGAAAAGAGACTGA

Upstream 100 bases:

>100_bases
CAGCAGATTATGTCAAAGAACAATTAAAAGACAGCTTAAACAAGTACGAAGTCAATAAATACATTTTGTAAAAAAATAAA
AAACACAGGAGGATTGAAAA

Downstream 100 bases:

>100_bases
CCCCTGCTACTTAGCAGGGGTTTTTTATTTTGGAAAATAGGACTTTTTTCTTATGGAGGAAAATGTTAAGACATGGTATA
ATAATATTCGATAAAATTTG

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTLLEKTRKLNRILQKTGIQPVDFMEMASILKEVIEANVYILSRKGKVLGYSALKDYGDEIFAKDKAIPEEYNDRLLRVT
ETLANDKGKLFKEEKALADLIVTVVPINGGGDRLGTLLLIRSTKEFTDDDLIIAEYGATVVGLEILRAKNEEIEEEARKR
AVVQMALATLSYSELQAIKNIFEELKGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNEKL
LEELEKMKRD

Sequences:

>Translated_250_residues
MTLLEKTRKLNRILQKTGIQPVDFMEMASILKEVIEANVYILSRKGKVLGYSALKDYGDEIFAKDKAIPEEYNDRLLRVT
ETLANDKGKLFKEEKALADLIVTVVPINGGGDRLGTLLLIRSTKEFTDDDLIIAEYGATVVGLEILRAKNEEIEEEARKR
AVVQMALATLSYSELQAIKNIFEELKGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNEKL
LEELEKMKRD
>Mature_249_residues
TLLEKTRKLNRILQKTGIQPVDFMEMASILKEVIEANVYILSRKGKVLGYSALKDYGDEIFAKDKAIPEEYNDRLLRVTE
TLANDKGKLFKEEKALADLIVTVVPINGGGDRLGTLLLIRSTKEFTDDDLIIAEYGATVVGLEILRAKNEEIEEEARKRA
VVQMALATLSYSELQAIKNIFEELKGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNEKLL
EELEKMKRD

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_THETN (Q8R9Y4)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623064.1
- ProteinModelPortal:   Q8R9Y4
- GeneID:   997888
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1446
- NMPDR:   fig|273068.3.peg.1411
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- BioCyc:   TTEN273068:TTE1446-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 27995; Mature: 27864

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLEKTRKLNRILQKTGIQPVDFMEMASILKEVIEANVYILSRKGKVLGYSALKDYGDE
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHH
IFAKDKAIPEEYNDRLLRVTETLANDKGKLFKEEKALADLIVTVVPINGGGDRLGTLLLI
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHEE
RSTKEFTDDDLIIAEYGATVVGLEILRAKNEEIEEEARKRAVVQMALATLSYSELQAIKN
ECCCCCCCCCEEEEHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEELKGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNEKL
HHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHH
LEELEKMKRD
HHHHHHHHCC
>Mature Secondary Structure 
TLLEKTRKLNRILQKTGIQPVDFMEMASILKEVIEANVYILSRKGKVLGYSALKDYGDE
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHH
IFAKDKAIPEEYNDRLLRVTETLANDKGKLFKEEKALADLIVTVVPINGGGDRLGTLLLI
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHEE
RSTKEFTDDDLIIAEYGATVVGLEILRAKNEEIEEEARKRAVVQMALATLSYSELQAIKN
ECCCCCCCCCEEEEHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEELKGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNEKL
HHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHH
LEELEKMKRD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336