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The map label for this gene is CheA2 [H]

Identifier: 20807864

GI number: 20807864

Start: 1396495

End: 1398435

Strand: Reverse

Name: CheA2 [H]

Synonym: TTE1417

Alternate gene names: 20807864

Gene position: 1398435-1396495 (Counterclockwise)

Preceding gene: 20807865

Following gene: 20807863

Centisome position: 52.0

GC content: 37.92

Gene sequence:

>1941_bases
ATGGAAACCAATCAATATATTGAGATATTTATAGAAGAGTCACAGGAACACATAGAAAATTTAAACAGCAACTTGCTCCT
TTTAGAAAAAGACCCTCAGAACAAGGGAGTAATTGATGAAATCTTCAGGTCTGCCCATACCTTAAAAGGAATGGCAGCTA
CTATGGGCTTTGAAAACATGAATAAGTTAGCCCACAAGATGGAAGATGTGCTTCAAGAAGTAAAGAACGGTAAACTGTCC
ATTACCAGCTCTATAATGGATATACTTTTTAAAAGCGTAGATGTTTTAGGTGAAATGCTAAACTCCATATCTCAAACAGG
AGAAGATTTTCCGGCAGACGACGTGATATTCTTGCTTTCGGGCATAAAGAAAATGCCGGGAAATGAAGAAAAGGCTATTA
CCTATAGTGGCAGTCTTTCTATTAACGAATACGAGGAAGATATAATAAGAGAAGCCTATAAAGAAAATTACAAGGCTTTT
AAAATAACTGTGCATATAGACAAAGGCTGCATGATGAAGTCTGCAAGGGCTTTTGTGATATTTAACAACCTCGATAAAAT
GGGAGACATAATAAATTCTTTTCCTCCTGTTGAGGATATAGAGGATGAAAAATTTGATTATAGCTTCACACTCCATTTTC
TCACAAAAGAAGAAAAGGAAAAGTTAGAAGAAATGCTCCTTGCCATTCCTGAAGTAGAAAGAGTAGAGATAGAGGAAATA
AATGTGACTCCTTCCAAGGAGGAAACAGAAGACACTCAGATTTTAGAAGCTGCTAAGAAGACGATAAGCCAGAATAAAAC
TTCAAAAAGCGTCAGGGTAGATATAGACAGACTCGACAATCTCATGAATTTGGTCAGCGAACTGATAATCATAAAGACCA
GGTTAGAAGGGCTGGAAGCTGATAACAAAAATCCAGAAACAGCAAATGCAATTGAATACTTGGAGAGAATTACTACCAGC
TTGCACGATGCAGTTATGAAGGTGAGGATGGTACCTGTAGAGAGGGTATTTAATAGATTCCCGAGGATGGTAAGAGACCT
CTCCCACGAGTTAGGGAAAAAAATTACACTCAATATGTATGGCCAGGAAACTGAGGTAGACAGGACTGTAATAGATGAAA
TTGGGGACCCTCTTGTTCACCTAATAAGAAATTCCATTGATCACGGAATAGAGCCGCCGGAGGAGAGGATAAAAAAGGGC
AAGCCTGAGGTGGGCACAATCAATTTAAAAGCCTATCACGAAGGAAATAACGTCATAATCGAAGTGAGCGATGATGGAAG
AGGAATTGACATTGAAAAGGTGAAAGAAAAAGCCATAGAAAGAGGACTTTACACTCAAGAGCAAATTGCTAGTCTTTCGA
AGGACAAGATATTTGAAATTTTATTTAAACCCGGCTTTAGCACAGCAGACAAAGTAACTGACATTTCTGGAAGAGGCGTA
GGATTAGATGTTGTAAAAAATAAGATTGAATCTTTGAATGGAACGATTGAGGTGTTCTCAGAGCCAGATAAAGGAACAAA
ATTTGTTATAAAGCTTCCTTTGACTTTGGCTATAATACAGGCTCTATTGGTGAAAGTAGGAGATGAAAAGTTTGCAATTC
CTCTAAATTCAATCTCCGAAATAGTCCACAAAAAAGAGGATGAAGTGAGAAATGTCCAAGGAAAGGAAATAGTTCTCTAC
AGGGGTCGAGTCATTCCAATAATTCGATTAAACGAAATACTTCAGACGAAAAAAGTGGAATCAAATGGAAATTTAATTTG
CGTGATAATCAAGAAAGGAGAAAATCTGGCCTGCTGCACAGTGGACGACTTAATTGGACAGCAGGAGATAGTCATAAAGC
CTTTAGGCAAATACTTATCCAACGTAAAGGTAATTGCAGGAGCAACTATATTAGGTGACGGACAGGTAGCGCTTATTGTG
GACGCCAATAATTTATTCTGA

Upstream 100 bases:

>100_bases
AAAGGAATGCCGTATAGTGCCATCAAAACAGGGCTGGTAGACAAAATTCTACCGCTAGATAAAATTCCACAGGAGATAAT
AGAGAAAGTGAGGGAGTTTT

Downstream 100 bases:

>100_bases
ATAGGAGGGAAGAATTTTGAGCCTATTTGTTGTGGCAAAGATTGAAGATGAAGAATACGCCATAGGAATTGAAAAGGTGC
AGACTATAGAGAAGATTTTG

Product: chemotaxis protein histidine kinase-like kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
METNQYIEIFIEESQEHIENLNSNLLLLEKDPQNKGVIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGKLS
ITSSIMDILFKSVDVLGEMLNSISQTGEDFPADDVIFLLSGIKKMPGNEEKAITYSGSLSINEYEEDIIREAYKENYKAF
KITVHIDKGCMMKSARAFVIFNNLDKMGDIINSFPPVEDIEDEKFDYSFTLHFLTKEEKEKLEEMLLAIPEVERVEIEEI
NVTPSKEETEDTQILEAAKKTISQNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNKNPETANAIEYLERITTS
LHDAVMKVRMVPVERVFNRFPRMVRDLSHELGKKITLNMYGQETEVDRTVIDEIGDPLVHLIRNSIDHGIEPPEERIKKG
KPEVGTINLKAYHEGNNVIIEVSDDGRGIDIEKVKEKAIERGLYTQEQIASLSKDKIFEILFKPGFSTADKVTDISGRGV
GLDVVKNKIESLNGTIEVFSEPDKGTKFVIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKEDEVRNVQGKEIVLY
RGRVIPIIRLNEILQTKKVESNGNLICVIIKKGENLACCTVDDLIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIV
DANNLF

Sequences:

>Translated_646_residues
METNQYIEIFIEESQEHIENLNSNLLLLEKDPQNKGVIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGKLS
ITSSIMDILFKSVDVLGEMLNSISQTGEDFPADDVIFLLSGIKKMPGNEEKAITYSGSLSINEYEEDIIREAYKENYKAF
KITVHIDKGCMMKSARAFVIFNNLDKMGDIINSFPPVEDIEDEKFDYSFTLHFLTKEEKEKLEEMLLAIPEVERVEIEEI
NVTPSKEETEDTQILEAAKKTISQNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNKNPETANAIEYLERITTS
LHDAVMKVRMVPVERVFNRFPRMVRDLSHELGKKITLNMYGQETEVDRTVIDEIGDPLVHLIRNSIDHGIEPPEERIKKG
KPEVGTINLKAYHEGNNVIIEVSDDGRGIDIEKVKEKAIERGLYTQEQIASLSKDKIFEILFKPGFSTADKVTDISGRGV
GLDVVKNKIESLNGTIEVFSEPDKGTKFVIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKEDEVRNVQGKEIVLY
RGRVIPIIRLNEILQTKKVESNGNLICVIIKKGENLACCTVDDLIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIV
DANNLF
>Mature_646_residues
METNQYIEIFIEESQEHIENLNSNLLLLEKDPQNKGVIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGKLS
ITSSIMDILFKSVDVLGEMLNSISQTGEDFPADDVIFLLSGIKKMPGNEEKAITYSGSLSINEYEEDIIREAYKENYKAF
KITVHIDKGCMMKSARAFVIFNNLDKMGDIINSFPPVEDIEDEKFDYSFTLHFLTKEEKEKLEEMLLAIPEVERVEIEEI
NVTPSKEETEDTQILEAAKKTISQNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNKNPETANAIEYLERITTS
LHDAVMKVRMVPVERVFNRFPRMVRDLSHELGKKITLNMYGQETEVDRTVIDEIGDPLVHLIRNSIDHGIEPPEERIKKG
KPEVGTINLKAYHEGNNVIIEVSDDGRGIDIEKVKEKAIERGLYTQEQIASLSKDKIFEILFKPGFSTADKVTDISGRGV
GLDVVKNKIESLNGTIEVFSEPDKGTKFVIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKEDEVRNVQGKEIVLY
RGRVIPIIRLNEILQTKKVESNGNLICVIIKKGENLACCTVDDLIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIV
DANNLF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=663, Percent_Identity=32.8808446455505, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72714; Mature: 72714

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNQYIEIFIEESQEHIENLNSNLLLLEKDPQNKGVIDEIFRSAHTLKGMAATMGFENM
CCCCCEEEEEEHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHH
NKLAHKMEDVLQEVKNGKLSITSSIMDILFKSVDVLGEMLNSISQTGEDFPADDVIFLLS
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GIKKMPGNEEKAITYSGSLSINEYEEDIIREAYKENYKAFKITVHIDKGCMMKSARAFVI
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHCCCEEEE
FNNLDKMGDIINSFPPVEDIEDEKFDYSFTLHFLTKEEKEKLEEMLLAIPEVERVEIEEI
ECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEE
NVTPSKEETEDTQILEAAKKTISQNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
DNKNPETANAIEYLERITTSLHDAVMKVRMVPVERVFNRFPRMVRDLSHELGKKITLNMY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEC
GQETEVDRTVIDEIGDPLVHLIRNSIDHGIEPPEERIKKGKPEVGTINLKAYHEGNNVII
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEEEEECCCEEEE
EVSDDGRGIDIEKVKEKAIERGLYTQEQIASLSKDKIFEILFKPGFSTADKVTDISGRGV
EECCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCC
GLDVVKNKIESLNGTIEVFSEPDKGTKFVIKLPLTLAIIQALLVKVGDEKFAIPLNSISE
CHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHH
IVHKKEDEVRNVQGKEIVLYRGRVIPIIRLNEILQTKKVESNGNLICVIIKKGENLACCT
HHHCCHHHHHCCCCCEEEEECCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
VDDLIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIVDANNLF
HHHHCCCCHHHHHHHHHHHCCCEEEECEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
METNQYIEIFIEESQEHIENLNSNLLLLEKDPQNKGVIDEIFRSAHTLKGMAATMGFENM
CCCCCEEEEEEHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHH
NKLAHKMEDVLQEVKNGKLSITSSIMDILFKSVDVLGEMLNSISQTGEDFPADDVIFLLS
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GIKKMPGNEEKAITYSGSLSINEYEEDIIREAYKENYKAFKITVHIDKGCMMKSARAFVI
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHCCCEEEE
FNNLDKMGDIINSFPPVEDIEDEKFDYSFTLHFLTKEEKEKLEEMLLAIPEVERVEIEEI
ECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEE
NVTPSKEETEDTQILEAAKKTISQNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
DNKNPETANAIEYLERITTSLHDAVMKVRMVPVERVFNRFPRMVRDLSHELGKKITLNMY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEC
GQETEVDRTVIDEIGDPLVHLIRNSIDHGIEPPEERIKKGKPEVGTINLKAYHEGNNVII
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEEEEECCCEEEE
EVSDDGRGIDIEKVKEKAIERGLYTQEQIASLSKDKIFEILFKPGFSTADKVTDISGRGV
EECCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCC
GLDVVKNKIESLNGTIEVFSEPDKGTKFVIKLPLTLAIIQALLVKVGDEKFAIPLNSISE
CHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHH
IVHKKEDEVRNVQGKEIVLYRGRVIPIIRLNEILQTKKVESNGNLICVIIKKGENLACCT
HHHCCHHHHHCCCCCEEEEECCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCCEEEEE
VDDLIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIVDANNLF
HHHHCCCCHHHHHHHHHHHCCCEEEECEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938941; 9384377 [H]