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The map label for this gene is SpeD

Identifier: 20807801

GI number: 20807801

Start: 1335625

End: 1335999

Strand: Direct

Name: SpeD

Synonym: TTE1354

Alternate gene names: 20807801

Gene position: 1335625-1335999 (Clockwise)

Preceding gene: 20807800

Following gene: 20807802

Centisome position: 49.66

GC content: 45.6

Gene sequence:

>375_bases
ATGAATGCTTTGGGTCGCCACATTTTGGCAGAAGTTTACGGTTGTGACAGCAGGATTTTAGACGATGTGGAAATGATCGA
AGATATCATGGTCCAAGCTGCAATAGCAACTGGCGCAGAAGTCAGAGAAGTGGCTTTTCACAAATTTAATCCCCAGGGCG
TAAGCGGAGTAGTAGTCATATCAGAGTCTCATTTAACCATTCATACGTGGCCAGAACTGGGCTATGCCGCGGTTGACGTA
TTCACGTGCGGTGACCATGTCAACCCGTGGGATGGCGTTAATTATATAGCGAGAATGTTAAAGGCAGAGAATATGACTGC
AACAGAGGTCAAGCGGGGGGTATTTGAGAAACCAGTTAAAGTTGCTAACTTCTAA

Upstream 100 bases:

>100_bases
TTAAACTGTCATGTAAAAAGCCTTGACAAAAGAGAAAAATTTGATAAAATTAAAGTCATTGAATGGGAACAAAATTTTAG
TAAAGGAGGCACGATACAAA

Downstream 100 bases:

>100_bases
CATATAAGATTTTCTAATCCTGTGTGGCTTTTATAGCCACTTTTTTCTATAATTAGGAGTGAAGATATTTATGGTAGGCT
ATGAGGAATTTGTTAAAAAA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MNALGRHILAEVYGCDSRILDDVEMIEDIMVQAAIATGAEVREVAFHKFNPQGVSGVVVISESHLTIHTWPELGYAAVDV
FTCGDHVNPWDGVNYIARMLKAENMTATEVKRGVFEKPVKVANF

Sequences:

>Translated_124_residues
MNALGRHILAEVYGCDSRILDDVEMIEDIMVQAAIATGAEVREVAFHKFNPQGVSGVVVISESHLTIHTWPELGYAAVDV
FTCGDHVNPWDGVNYIARMLKAENMTATEVKRGVFEKPVKVANF
>Mature_124_residues
MNALGRHILAEVYGCDSRILDDVEMIEDIMVQAAIATGAEVREVAFHKFNPQGVSGVVVISESHLTIHTWPELGYAAVDV
FTCGDHVNPWDGVNYIARMLKAENMTATEVKRGVFEKPVKVANF

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_THETN (Q8RA74)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622972.1
- ProteinModelPortal:   Q8RA74
- SMR:   Q8RA74
- GeneID:   997756
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1354
- NMPDR:   fig|273068.3.peg.113
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   PRK03124
- BioCyc:   TTEN273068:TTE1354-MONOMER
- BRENDA:   4.1.1.50
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13674; Mature: 13674

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALGRHILAEVYGCDSRILDDVEMIEDIMVQAAIATGAEVREVAFHKFNPQGVSGVVVI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLTIHTWPELGYAAVDVFTCGDHVNPWDGVNYIARMLKAENMTATEVKRGVFEKPVK
ECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
VANF
CCCC
>Mature Secondary Structure
MNALGRHILAEVYGCDSRILDDVEMIEDIMVQAAIATGAEVREVAFHKFNPQGVSGVVVI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLTIHTWPELGYAAVDVFTCGDHVNPWDGVNYIARMLKAENMTATEVKRGVFEKPVK
ECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
VANF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336