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The map label for this gene is ThrC [H]

Identifier: 20807688

GI number: 20807688

Start: 1237285

End: 1238673

Strand: Direct

Name: ThrC [H]

Synonym: TTE1236

Alternate gene names: 20807688

Gene position: 1237285-1238673 (Clockwise)

Preceding gene: 20807687

Following gene: 20807689

Centisome position: 46.01

GC content: 42.33

Gene sequence:

>1389_bases
ATGGCGCGAAAAAATGAGATTATGAAAAAATCTCTAGGAATAGACTATGAAAGATTTGAATCAGGCAGTATTGCTTTTGA
CTATGAGAGAATGATGAGAGAGACAGGTTACAGCTTAGAAGAGATAATTAAGATACAAAGAGAAGCCAATGTGGGCAATA
CTCCTTTAATAGAATTGAAAAATTTAACGGAGCTTGCAAGAAAAGTGTCTCCAACCGGCAAAGCCGCCAGAATATTTATT
AAAGATGAAGCCTGCAATCCTTCAGGAAGCTTTAAAGAAAGAAGAGCTAGCGTTTCTGTGTATCATGCGAAAAAGCACGG
TTACAAAGGAGTCATAGCAGCTACAAGCGGAAATTACGGTGCGGCAGTTGCCTCTCAAGCGGCAATGAAAGGGCTAAAGT
GCATTGTGGTACAAGAGGCATATGACAGCAGAGGTATAGGTCAGCCGGAAATCCTAGAAAAAGGGAGAAAATGCGAGACC
TTTGGTGCAGAGGTTGTACAGCTAACTGTTGGACCAGAATTATTTTATGTAAACTTGATGCTTTTAGAGGAGACGGGATA
CTTTAATGCTTCTCTTTACACGCCTTTTGGGATTGCGGGTATTGAAACATTAGGGTATGAGATAGCAAATCAGGTAAAAG
AGAGGACGGGCAAATTCCCTGATGTAGTGGTTGTGACTCACGCAGGGGGAGGGAATTTGACAGGTACTGCAAGAGGCCTT
ATAAAGGCAGGGGCTTTAGATACGAAGGTGTACGGAGTGAGCGTTGATTTGACAGGGCTACACATGGCTTCAGACACTGA
TTTTAACAGAAAATCCTTTACAACAGGCCATACCGGTTTTGGCATACCTTTTGCGACATGGCCGGATAGGGCGGATGTGC
CGAGAAATGCTGCAAGGCCTTTGAGATACATGGACGGGTATTACCTTGTAAAGCAGGGAGAAGTATTTTACATGACAGAG
CTTCTTGCTCAGTTAGAAGGATTAGAGAGGGGACCTGCTGGCAATACCTCGTTAGCTGCAGCTTTTAGCTTGGCACAGCA
GATGGAAAATGACCAGATAATAGTTGTTCAGGAGACAGAATACACTGGGGCAGGTAAAAACCCAACTGCTCAGCTGACTT
TTGCTAAGCAAAATGGAGTTCAGGTGCTTGTAGGAAATCCTGATGAGGAAGTTCCGGGTAAAAACATAATTCTTCCTGAA
CATCCTTCAATGGTCAAAGCGAGAGAAGTGAAACTTGATAATTTGAAGAAATCTTACATTAGAAATTGCATCCAGCACTT
TGGAATGCCAAATGAAGAAGACATAAAATTTTTGGCTGAGGATACCAAGTCCAGTGAAGATTTTGTGAGAAGGACAATTG
AAGAATTAAAGAATGGAGGGTTAGTATGA

Upstream 100 bases:

>100_bases
CACGACTTTGGGAGTCCAGTTCCGGAGCTTATAAAGGCTGGCATGAAGGCAAGAGAAATATTGTACGGCGGTGAAGGCAA
TGAGCAGGTATAAGGAGATA

Downstream 100 bases:

>100_bases
GAAGGGAAGACGATTTTGAAGTGAGAAGTAAGCACTTGCAACACATGACAGATGAAGAATTAGATGCCTACTTTTGGGAG
TTGGCGGAAAAAATTGTGGA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MARKNEIMKKSLGIDYERFESGSIAFDYERMMRETGYSLEEIIKIQREANVGNTPLIELKNLTELARKVSPTGKAARIFI
KDEACNPSGSFKERRASVSVYHAKKHGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCET
FGAEVVQLTVGPELFYVNLMLLEETGYFNASLYTPFGIAGIETLGYEIANQVKERTGKFPDVVVVTHAGGGNLTGTARGL
IKAGALDTKVYGVSVDLTGLHMASDTDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQGEVFYMTE
LLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAKQNGVQVLVGNPDEEVPGKNIILPE
HPSMVKAREVKLDNLKKSYIRNCIQHFGMPNEEDIKFLAEDTKSSEDFVRRTIEELKNGGLV

Sequences:

>Translated_462_residues
MARKNEIMKKSLGIDYERFESGSIAFDYERMMRETGYSLEEIIKIQREANVGNTPLIELKNLTELARKVSPTGKAARIFI
KDEACNPSGSFKERRASVSVYHAKKHGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCET
FGAEVVQLTVGPELFYVNLMLLEETGYFNASLYTPFGIAGIETLGYEIANQVKERTGKFPDVVVVTHAGGGNLTGTARGL
IKAGALDTKVYGVSVDLTGLHMASDTDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQGEVFYMTE
LLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAKQNGVQVLVGNPDEEVPGKNIILPE
HPSMVKAREVKLDNLKKSYIRNCIQHFGMPNEEDIKFLAEDTKSSEDFVRRTIEELKNGGLV
>Mature_461_residues
ARKNEIMKKSLGIDYERFESGSIAFDYERMMRETGYSLEEIIKIQREANVGNTPLIELKNLTELARKVSPTGKAARIFIK
DEACNPSGSFKERRASVSVYHAKKHGYKGVIAATSGNYGAAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETF
GAEVVQLTVGPELFYVNLMLLEETGYFNASLYTPFGIAGIETLGYEIANQVKERTGKFPDVVVVTHAGGGNLTGTARGLI
KAGALDTKVYGVSVDLTGLHMASDTDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARPLRYMDGYYLVKQGEVFYMTEL
LAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETEYTGAGKNPTAQLTFAKQNGVQVLVGNPDEEVPGKNIILPEH
PSMVKAREVKLDNLKKSYIRNCIQHFGMPNEEDIKFLAEDTKSSEDFVRRTIEELKNGGLV

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321412, Length=325, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 50740; Mature: 50609

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKNEIMKKSLGIDYERFESGSIAFDYERMMRETGYSLEEIIKIQREANVGNTPLIELK
CCCHHHHHHHHHCCCHHHCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEHH
NLTELARKVSPTGKAARIFIKDEACNPSGSFKERRASVSVYHAKKHGYKGVIAATSGNYG
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEECCCCC
AAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETFGAEVVQLTVGPELFYVNLM
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCEEEEEEEE
LLEETGYFNASLYTPFGIAGIETLGYEIANQVKERTGKFPDVVVVTHAGGGNLTGTARGL
EEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
IKAGALDTKVYGVSVDLTGLHMASDTDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARP
HCCCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LRYMDGYYLVKQGEVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETE
HHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
YTGAGKNPTAQLTFAKQNGVQVLVGNPDEEVPGKNIILPEHPSMVKAREVKLDNLKKSYI
CCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
RNCIQHFGMPNEEDIKFLAEDTKSSEDFVRRTIEELKNGGLV
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARKNEIMKKSLGIDYERFESGSIAFDYERMMRETGYSLEEIIKIQREANVGNTPLIELK
CCHHHHHHHHHCCCHHHCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEHH
NLTELARKVSPTGKAARIFIKDEACNPSGSFKERRASVSVYHAKKHGYKGVIAATSGNYG
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHCEEEEEEECCCCCCEEEEEECCCCC
AAVASQAAMKGLKCIVVQEAYDSRGIGQPEILEKGRKCETFGAEVVQLTVGPELFYVNLM
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCEEEEEEEE
LLEETGYFNASLYTPFGIAGIETLGYEIANQVKERTGKFPDVVVVTHAGGGNLTGTARGL
EEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
IKAGALDTKVYGVSVDLTGLHMASDTDFNRKSFTTGHTGFGIPFATWPDRADVPRNAARP
HCCCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LRYMDGYYLVKQGEVFYMTELLAQLEGLERGPAGNTSLAAAFSLAQQMENDQIIVVQETE
HHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
YTGAGKNPTAQLTFAKQNGVQVLVGNPDEEVPGKNIILPEHPSMVKAREVKLDNLKKSYI
CCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH
RNCIQHFGMPNEEDIKFLAEDTKSSEDFVRRTIEELKNGGLV
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]