Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 20807653

GI number: 20807653

Start: 1197164

End: 1198381

Strand: Reverse

Name: macB [H]

Synonym: TTE1198

Alternate gene names: 20807653

Gene position: 1198381-1197164 (Counterclockwise)

Preceding gene: 20807654

Following gene: 20807621

Centisome position: 44.56

GC content: 35.71

Gene sequence:

>1218_bases
GTGAGAATAATGTATATCTGGGAAGCCTTTAAAGTAGCCATTGAAAGTATCTTAAGTAATAAGCTCAGAACTTTCCTAAC
AATGTTGGGTATCATAATAGGAATCGCTTCTGTGATAACAATTGTGTCTTTGGGAGCAGGAGGGCAAAAGGCAATATTAG
GAGAGTTTGAAAAAATAGGCGTAAATGTATTTTCTATAAAAATGAGAAACGACGTGGACATTCGAGAGGGCGATAGGTTA
ACCTTAAGAGATGTAGAAATGATAAGAAAAAGATTGCCTTCTGTAAAATACGCTGCACCAGTAGCAGAAAAAATGGGACT
TGCTAAAACTGAAAAATACACTAAAAGAGCTCTTTTTATAGGAACAGACTTTGACTATGGCAATATTTCCAGCCTCAAAG
TAATTCACGGGAGATTCCTAAATGAAAAGGACATCTTATTAGGAAGAAATGTAATACTCATTGATAAAGACTCAGCTATA
GAACTGTTTGGCTATGAAGACTGTGTAGGAAAGAGTATTAAAATAGGCACCTATTATTATTTTGATACAGCGAAGATAAT
TGGCGTCATAGACAGTGGAAATTTAAAAAGCTTAGGTGGATCAATAGCTGATCAAATACCCATAATCGCTGCAATTCCTA
TAACTTACGCACAAAAAATTTTCCCTGACATAAACATATCTCAAATTTATGTAATGACTTACGACCAAAGCCAATTAGAA
GAAGCTTCTTCCCAGGCAGTGCGTTTAATAGAATCATTACACCACAACAAAGACAAATACAAGACAGAAAATCTTATAAG
TTTTTTAGAGGAATTTAACAGAATCCTTGGGATATTTACAACTGTGATAGGTGCGATTGCGGGTATTTCTCTCTTGGTAG
GCGGAATAGGAATTATGAATATAATGCTTGTCTCTGTAACTGAACGCACCAAAGAAATAGGGATAAGAAAGGCAGTAGGT
GCAAGGAGAAAAGATATAATGATACAGTTTTTGATAGAGTCTGTTACCATATCCCTTATAGGAGGAGCAATAGGAATTTT
GCTGGGATACCTCTTAGCTAATATCGTAGGCCCCTTTATCGACATAAAACCAATTATTTCAATAAACGCGATACTTATCG
CTTTCTTCTTCTCCACCGCAGTTGGAATATTCTTTGGAATATACCCTGCTCAAAAAGCAGCAAAACTAGACCCAATAGTA
GCATTGAGATATGAATAA

Upstream 100 bases:

>100_bases
TGAACAAGACATTGCAAATCATGCAAAAAGAATAGTTCGCTTAAGAGATGGGCTCATTGTAGAAGACAGTTTGGTTTCAA
ATAGAATAACTTATTGACAG

Downstream 100 bases:

>100_bases
AAAGCAAGGGGATAAATTCCTCTTGCTTTTTATACTAAATTTTTCAAAAACATATTAAGCCTTTTTTCCCTTCCTATTGT
GGAAAAATCACCATGGCCCG

Product: ABC-type transport systems, involved in lipoprotein release, permease components

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRIMYIWEAFKVAIESILSNKLRTFLTMLGIIIGIASVITIVSLGAGGQKAILGEFEKIGVNVFSIKMRNDVDIREGDRL
TLRDVEMIRKRLPSVKYAAPVAEKMGLAKTEKYTKRALFIGTDFDYGNISSLKVIHGRFLNEKDILLGRNVILIDKDSAI
ELFGYEDCVGKSIKIGTYYYFDTAKIIGVIDSGNLKSLGGSIADQIPIIAAIPITYAQKIFPDINISQIYVMTYDQSQLE
EASSQAVRLIESLHHNKDKYKTENLISFLEEFNRILGIFTTVIGAIAGISLLVGGIGIMNIMLVSVTERTKEIGIRKAVG
ARRKDIMIQFLIESVTISLIGGAIGILLGYLLANIVGPFIDIKPIISINAILIAFFFSTAVGIFFGIYPAQKAAKLDPIV
ALRYE

Sequences:

>Translated_405_residues
MRIMYIWEAFKVAIESILSNKLRTFLTMLGIIIGIASVITIVSLGAGGQKAILGEFEKIGVNVFSIKMRNDVDIREGDRL
TLRDVEMIRKRLPSVKYAAPVAEKMGLAKTEKYTKRALFIGTDFDYGNISSLKVIHGRFLNEKDILLGRNVILIDKDSAI
ELFGYEDCVGKSIKIGTYYYFDTAKIIGVIDSGNLKSLGGSIADQIPIIAAIPITYAQKIFPDINISQIYVMTYDQSQLE
EASSQAVRLIESLHHNKDKYKTENLISFLEEFNRILGIFTTVIGAIAGISLLVGGIGIMNIMLVSVTERTKEIGIRKAVG
ARRKDIMIQFLIESVTISLIGGAIGILLGYLLANIVGPFIDIKPIISINAILIAFFFSTAVGIFFGIYPAQKAAKLDPIV
ALRYE
>Mature_405_residues
MRIMYIWEAFKVAIESILSNKLRTFLTMLGIIIGIASVITIVSLGAGGQKAILGEFEKIGVNVFSIKMRNDVDIREGDRL
TLRDVEMIRKRLPSVKYAAPVAEKMGLAKTEKYTKRALFIGTDFDYGNISSLKVIHGRFLNEKDILLGRNVILIDKDSAI
ELFGYEDCVGKSIKIGTYYYFDTAKIIGVIDSGNLKSLGGSIADQIPIIAAIPITYAQKIFPDINISQIYVMTYDQSQLE
EASSQAVRLIESLHHNKDKYKTENLISFLEEFNRILGIFTTVIGAIAGISLLVGGIGIMNIMLVSVTERTKEIGIRKAVG
ARRKDIMIQFLIESVTISLIGGAIGILLGYLLANIVGPFIDIKPIISINAILIAFFFSTAVGIFFGIYPAQKAAKLDPIV
ALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=406, Percent_Identity=37.192118226601, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44691; Mature: 44691

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIMYIWEAFKVAIESILSNKLRTFLTMLGIIIGIASVITIVSLGAGGQKAILGEFEKIG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
VNVFSIKMRNDVDIREGDRLTLRDVEMIRKRLPSVKYAAPVAEKMGLAKTEKYTKRALFI
CEEEEEEECCCCCCCCCCEEEHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHCEEEEE
GTDFDYGNISSLKVIHGRFLNEKDILLGRNVILIDKDSAIELFGYEDCVGKSIKIGTYYY
ECCCCCCCCCHHHEEHHHCCCCCCEEECCCEEEEECCCCEEEECCHHHCCCEEEEEEEEE
FDTAKIIGVIDSGNLKSLGGSIADQIPIIAAIPITYAQKIFPDINISQIYVMTYDQSQLE
EECEEEEEEECCCCCHHHCCHHHHCCCEEEECHHHHHHHHCCCCCCCEEEEEECCHHHHH
EASSQAVRLIESLHHNKDKYKTENLISFLEEFNRILGIFTTVIGAIAGISLLVGGIGIMN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERTKEIGIRKAVGARRKDIMIQFLIESVTISLIGGAIGILLGYLLANIVGPFI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIKPIISINAILIAFFFSTAVGIFFGIYPAQKAAKLDPIVALRYE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEECC
>Mature Secondary Structure
MRIMYIWEAFKVAIESILSNKLRTFLTMLGIIIGIASVITIVSLGAGGQKAILGEFEKIG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
VNVFSIKMRNDVDIREGDRLTLRDVEMIRKRLPSVKYAAPVAEKMGLAKTEKYTKRALFI
CEEEEEEECCCCCCCCCCEEEHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHCEEEEE
GTDFDYGNISSLKVIHGRFLNEKDILLGRNVILIDKDSAIELFGYEDCVGKSIKIGTYYY
ECCCCCCCCCHHHEEHHHCCCCCCEEECCCEEEEECCCCEEEECCHHHCCCEEEEEEEEE
FDTAKIIGVIDSGNLKSLGGSIADQIPIIAAIPITYAQKIFPDINISQIYVMTYDQSQLE
EECEEEEEEECCCCCHHHCCHHHHCCCEEEECHHHHHHHHCCCCCCCEEEEEECCHHHHH
EASSQAVRLIESLHHNKDKYKTENLISFLEEFNRILGIFTTVIGAIAGISLLVGGIGIMN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVSVTERTKEIGIRKAVGARRKDIMIQFLIESVTISLIGGAIGILLGYLLANIVGPFI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIKPIISINAILIAFFFSTAVGIFFGIYPAQKAAKLDPIVALRYE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA