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The map label for this gene is ruvB [H]

Identifier: 20807636

GI number: 20807636

Start: 1178276

End: 1179292

Strand: Direct

Name: ruvB [H]

Synonym: TTE1180

Alternate gene names: 20807636

Gene position: 1178276-1179292 (Clockwise)

Preceding gene: 20807635

Following gene: 20807637

Centisome position: 43.81

GC content: 39.63

Gene sequence:

>1017_bases
ATGGAAGAAAGGATATTGACTCAAAATTTTACTCAAGAGGATGCGACGGAATACAGTCTCCGTCCCAGGTGGCTTTCTGA
GTACATAGGACAGGAGAAAATAAAACAGGAGCTAAAAATCTATATAGAAGCAGCTAAAAAAAGAGGAGAACCACTAGACC
ATGTCCTACTTTACGGTCCTCCCGGGCTTGGGAAGACTACTTTAGCTACAGTTATTTCTAATGAAATGGGTGTAGGCATA
AAAATAACTTCAGGACCTGCTATAGAGAGGTCTGGAGATTTAGCCGCAATTTTGACGAATTTGCAGGAGAATGACATACT
CTTTATAGACGAGATTCACAGATTAAACAGAAGCGTTGAGGAGATTTTGTATCCTGCTATGGAAGATTTTGAGCTTGACA
TAGTAATAGGGAAGGGACCAAGCGCTCGGTCTATAAGGCTTAGCCTTCCTAAATTTACGCTTATTGGAGCTACTACAAGG
GCAGCTCTCATGACTTCTCCTTTAAGGAGTAGATTTGGAGTCATAAATCGCCTTGATTATTATTCAGTAGAGGAATTAAA
GGAAATTATAAAAAGGTCAGCTAATATTTTGAATATTGGTATTGACGAAGATGCAGCTTTTGAGATAGCTAGAAGGTCCA
GAGGAACTCCCAGAATAGCCAACAGGCTTTTAAAAAGGGTGAGAGATTTCGCGGAAGTGAAAGGAAATGGCTATATTGAT
TACAATACGGCAAATATAGCTTTAAACATGCTTGGGGTCGATGAAATGGGTTTAGAGGAAATTGATAGAAAGATCTTGAT
TGCAATAATAGAGAAGTTTGGCGGAGGACCTGTTGGAATTGATGCTATTGCTGCATCAGTTGGTGAAGATGGGGATACAA
TAGAAGATATGTACGAGCCTTATCTCATGCAGATAGGATTTTTAAATAGAACTCCAAGAGGGAGAGTAGTTACAAAACTG
GCCTATCAGTATCTTAAGTACCCTTATGTTGAGCAGAGGAGGATTGAGGATGTTTGA

Upstream 100 bases:

>100_bases
AAAAGTGAGGCTATTTACGCTCTTTCTGATGTAAACTGTGAAAGTGTGGAACAGGCTGTCAAAGAGGCGCTGAAAAAATT
GGCGAAATAGGGTGAAGTAA

Downstream 100 bases:

>100_bases
CAGCTTTGGCAAAATGTTAATATTTATGGGAGCAATTTTAATCGCCATAGGACTTCTTTTTTCAGCAGGTTCAAAAATTG
GTTTGGGCCGTTTGCCAGGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTR
AALMTSPLRSRFGVINRLDYYSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYID
YNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEPYLMQIGFLNRTPRGRVVTKL
AYQYLKYPYVEQRRIEDV

Sequences:

>Translated_338_residues
MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTR
AALMTSPLRSRFGVINRLDYYSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYID
YNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEPYLMQIGFLNRTPRGRVVTKL
AYQYLKYPYVEQRRIEDV
>Mature_338_residues
MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTR
AALMTSPLRSRFGVINRLDYYSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYID
YNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEPYLMQIGFLNRTPRGRVVTKL
AYQYLKYPYVEQRRIEDV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=324, Percent_Identity=57.4074074074074, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787119, Length=239, Percent_Identity=30.5439330543933, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38073; Mature: 38073

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGP
CCCCCCCCCCCCHHCHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PGLGKTTLATVISNEMGVGIKITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVE
CCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTRAALMTSPLRSRFGVINRLDY
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
YSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYID
CCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEP
EEHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
YLMQIGFLNRTPRGRVVTKLAYQYLKYPYVEQRRIEDV
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MEERILTQNFTQEDATEYSLRPRWLSEYIGQEKIKQELKIYIEAAKKRGEPLDHVLLYGP
CCCCCCCCCCCCHHCHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PGLGKTTLATVISNEMGVGIKITSGPAIERSGDLAAILTNLQENDILFIDEIHRLNRSVE
CCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDFELDIVIGKGPSARSIRLSLPKFTLIGATTRAALMTSPLRSRFGVINRLDY
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
YSVEELKEIIKRSANILNIGIDEDAAFEIARRSRGTPRIANRLLKRVRDFAEVKGNGYID
CCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
YNTANIALNMLGVDEMGLEEIDRKILIAIIEKFGGGPVGIDAIAASVGEDGDTIEDMYEP
EEHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
YLMQIGFLNRTPRGRVVTKLAYQYLKYPYVEQRRIEDV
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA