Click here to switch to the map view.

The map label for this gene is msbA [C]

Identifier: 20807630

GI number: 20807630

Start: 1174602

End: 1174961

Strand: Direct

Name: msbA [C]

Synonym: TTE1174

Alternate gene names: 20807630

Gene position: 1174602-1174961 (Clockwise)

Preceding gene: 20807629

Following gene: 20807631

Centisome position: 43.67

GC content: 28.33

Gene sequence:

>360_bases
GTGGAGGTTTACGATTATAAAACTATTGATAAACTGCTAAAAGATTTAAATGTAAATATAGATAAATTTCATGAAGGATT
GAATACAAAACTAAATGAAGCCTCAAGCAATATTTCAAGAGGAGAAAAATTAAAGATAGCGATTGCAAGGACATTTTTAA
AAGATCCAGATGTTATAGTGTTAGATGAGCCCACGTCTGCCTTAGATGTTGTTAGTATTGAGAAATTAAAATCTATGCTA
ACAGCACTCAAGAAAGAAAAAATAATTTTAATTGTTACTCATAATCAAGAGTTTTTAAATATAGCGGATGAAGTGATAGA
TTTAAATAGAATTTCTAAAAAGGTGGAATGTTTGGTGTAA

Upstream 100 bases:

>100_bases
CAGATACAAATGCTGGCTATCCAGAAGTAAGAGCAGAAATATTGAAGCAAAAGACAGTTGAAGTGATTAAGTCTTTAGAA
AAAGGCAATTTCTAAAAGGG

Downstream 100 bases:

>100_bases
GAAGTTTCACAAGTTTTGAATTTAGAAATTCTATAGAAATCAAGAACCTAACCTTTTCCTACGATGGGAAGAGGAATGCT
TTACTTGCTGTAACCCATAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MEVYDYKTIDKLLKDLNVNIDKFHEGLNTKLNEASSNISRGEKLKIAIARTFLKDPDVIVLDEPTSALDVVSIEKLKSML
TALKKEKIILIVTHNQEFLNIADEVIDLNRISKKVECLV

Sequences:

>Translated_119_residues
MEVYDYKTIDKLLKDLNVNIDKFHEGLNTKLNEASSNISRGEKLKIAIARTFLKDPDVIVLDEPTSALDVVSIEKLKSML
TALKKEKIILIVTHNQEFLNIADEVIDLNRISKKVECLV
>Mature_119_residues
MEVYDYKTIDKLLKDLNVNIDKFHEGLNTKLNEASSNISRGEKLKIAIARTFLKDPDVIVLDEPTSALDVVSIEKLKSML
TALKKEKIILIVTHNQEFLNIADEVIDLNRISKKVECLV

Specific function: Involved In Lipid A Export And Possibly Also In Glycerophospholipid Export And For Biogenesis Of The Outer Membrane. Transmembrane Domains (Tmd) Form A Pore In The Inner Membrane And The ATP-Binding Domain (Nbd) Is Responsible For Energy Generation. [C]

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=98, Percent_Identity=34.6938775510204, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787143, Length=87, Percent_Identity=36.7816091954023, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787112, Length=101, Percent_Identity=33.6633663366337, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1790162, Length=68, Percent_Identity=38.2352941176471, Blast_Score=62, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=93, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=86, Percent_Identity=36.046511627907, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17511077, Length=94, Percent_Identity=36.1702127659575, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=87, Percent_Identity=34.4827586206897, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=87, Percent_Identity=34.4827586206897, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=87, Percent_Identity=35.632183908046, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=75, Percent_Identity=38.6666666666667, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI85726357, Length=91, Percent_Identity=35.1648351648352, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397593, Length=99, Percent_Identity=32.3232323232323, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363262, Length=89, Percent_Identity=35.9550561797753, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=89, Percent_Identity=35.9550561797753, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357907, Length=98, Percent_Identity=36.734693877551, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 13524; Mature: 13524

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVYDYKTIDKLLKDLNVNIDKFHEGLNTKLNEASSNISRGEKLKIAIARTFLKDPDVIV
CCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCEEEHHHHHHHCCCCCEEE
LDEPTSALDVVSIEKLKSMLTALKKEKIILIVTHNQEFLNIADEVIDLNRISKKVECLV
EECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVYDYKTIDKLLKDLNVNIDKFHEGLNTKLNEASSNISRGEKLKIAIARTFLKDPDVIV
CCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCEEEHHHHHHHCCCCCEEE
LDEPTSALDVVSIEKLKSMLTALKKEKIILIVTHNQEFLNIADEVIDLNRISKKVECLV
EECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]