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The map label for this gene is HyuA [H]

Identifier: 20807581

GI number: 20807581

Start: 1120955

End: 1122631

Strand: Direct

Name: HyuA [H]

Synonym: TTE1121

Alternate gene names: 20807581

Gene position: 1120955-1122631 (Clockwise)

Preceding gene: 20807580

Following gene: 20807582

Centisome position: 41.68

GC content: 32.38

Gene sequence:

>1677_bases
TTGATCATCGGTCTTGATATGGGAGGAACTAATATAGACGGAGTTATCGTAGAAAAAGGCAAGATTATAAAAACCATAAA
AAAACCTACAAATAGAGATAATTTATTTAACTCCATCTGGACTGCCCTTAAAGAACTGCTTTCAGGATATGATAATACTA
AAATAGAAAGGATAAATTTAAGCACCACTGTATCTACCAACGCCATAGTTGAAAATAAACTTTCTCCTGTAGGAATGATT
ATTCAACCTGGTCCAGGTTTGCCTTATGATTTTTTAGCCTGCGGTGATGAAAATGTATTTATATCTGGATATATTGATTA
CAGAGGTGAAATAATTAAAGATTTTAATTTGTTTGAAATAGAAAATGCCATTAAATTATTCAAAGAAAAAAATATTAAAG
CTTATGCTGTAGTCACTAAATTTTCTATTAGAAATCCTAGCATTGAAATAAAAATAAAAGAAATTTTGGAAAATGAAATA
CCCAACTCTTTTGTTACCATGGGACATACTATATCAGGCAAGTTAAATTTCCCTCGCAGAGTGTATACTTCTTATTTAAA
TTCAGCAGTGCACAGTATTTTTAATGAATTTTTAAATAATATTAAAAAATCCCTAGAAAAAGAAGGAATAAATGCACCAG
TATTTATATTAAAAGCCGACGGCGGCACTATGAATATCTCTACAGCAGAAAAAAAACCAGTAGAAACTATCCTATCTGGT
CCTGCTGCCAGCCTTATGGGAATTAATGCTATGCTTCCTACCAATGAAGATGCAATATTACTAGATATTGGAGGTACTAC
TACAGACATATTTTTCCTTGCCGATGGAGTTCCTTTATTTGAACCGTGGGGAATAAGAATAGGTAAATATAAAACTTTAA
TAAGAGCAATTTATAGTGTTTCCATAGGTTTAGGTGGAGATAGTAGTATTTGTGTTAGAAATGGCAGGATAAAAATAGGC
CCCCAAAGAGAAGGAGTGCCTTACGCTTTTGGTGGTCCCAAACCTACTCCTACAGATGCCATGATAACCTTAGAGTTGAT
AGATGAAAATGCATTTAGCCTCACTCAGGATAATGTTAAAAAAGCTTATGAAGCAATGACTTTATTGGGAAAAGAGTTAA
ATTTATCAGCAAAAGATATGGCAAAATTAATTCTCAGCACTATGGGAGATATTATTAAAAATAAAGTAGATGAACTTTTA
CATGAAATAAATAGCCGTCCCGTTTATACTGTAAAAGAATTATTGTACGGGAAAAAAATTAAACCTAAGCTGATAAATAT
AATTGGTGGTCCTTCTAAAGTATTAGCCCCTGTACTTGAAGAAAAGTTTAATTTACCTTGCTATTACCCTAAAAACTATT
CTGTAGCCAACGCTGTAGGTGCAGCTTTAGCACGACCAACTACTGAAATTACAATGCTTGTTGATACTTCTAAAAAAACA
CTTTCTGTACCTGAATTAGGATTATATGAAAAAATAACTGGAAATTATACTCTTGATAAAGCAAAAGAAAAAGCTTTAGA
ATTAGTCAAAAAATCTGCTCTATCTCTGGGCGCTTCTATTGAGGAAATAGAAGCTGAAATAGTAGAAGAAAGTAGCTTCA
ATATGGTAAGAGGATTTTATACTATCGGAAAGAACATGCGAATTAAAGCTCAGGTAAAACCAGGACTTATCCAATAA

Upstream 100 bases:

>100_bases
AAAAATTTTCTCTGTGAGAATACAAAATACAAAAAACATTAAAATATAAAATGGCGTGGAAATTTATAATAATATTATTC
CAAAGAAAGGAGGTTTTTAA

Downstream 100 bases:

>100_bases
ATTGAGAGGTGAATGAGAATGATTAAAGCTAAAAATAGATTGGGCATTGTATTCTTTCCTGCTTTTGACTGGGCTATTAG
TCCTACTCATCCAGAAAGAG

Product: N-methylhydaintoinase A

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MIIGLDMGGTNIDGVIVEKGKIIKTIKKPTNRDNLFNSIWTALKELLSGYDNTKIERINLSTTVSTNAIVENKLSPVGMI
IQPGPGLPYDFLACGDENVFISGYIDYRGEIIKDFNLFEIENAIKLFKEKNIKAYAVVTKFSIRNPSIEIKIKEILENEI
PNSFVTMGHTISGKLNFPRRVYTSYLNSAVHSIFNEFLNNIKKSLEKEGINAPVFILKADGGTMNISTAEKKPVETILSG
PAASLMGINAMLPTNEDAILLDIGGTTTDIFFLADGVPLFEPWGIRIGKYKTLIRAIYSVSIGLGGDSSICVRNGRIKIG
PQREGVPYAFGGPKPTPTDAMITLELIDENAFSLTQDNVKKAYEAMTLLGKELNLSAKDMAKLILSTMGDIIKNKVDELL
HEINSRPVYTVKELLYGKKIKPKLINIIGGPSKVLAPVLEEKFNLPCYYPKNYSVANAVGAALARPTTEITMLVDTSKKT
LSVPELGLYEKITGNYTLDKAKEKALELVKKSALSLGASIEEIEAEIVEESSFNMVRGFYTIGKNMRIKAQVKPGLIQ

Sequences:

>Translated_558_residues
MIIGLDMGGTNIDGVIVEKGKIIKTIKKPTNRDNLFNSIWTALKELLSGYDNTKIERINLSTTVSTNAIVENKLSPVGMI
IQPGPGLPYDFLACGDENVFISGYIDYRGEIIKDFNLFEIENAIKLFKEKNIKAYAVVTKFSIRNPSIEIKIKEILENEI
PNSFVTMGHTISGKLNFPRRVYTSYLNSAVHSIFNEFLNNIKKSLEKEGINAPVFILKADGGTMNISTAEKKPVETILSG
PAASLMGINAMLPTNEDAILLDIGGTTTDIFFLADGVPLFEPWGIRIGKYKTLIRAIYSVSIGLGGDSSICVRNGRIKIG
PQREGVPYAFGGPKPTPTDAMITLELIDENAFSLTQDNVKKAYEAMTLLGKELNLSAKDMAKLILSTMGDIIKNKVDELL
HEINSRPVYTVKELLYGKKIKPKLINIIGGPSKVLAPVLEEKFNLPCYYPKNYSVANAVGAALARPTTEITMLVDTSKKT
LSVPELGLYEKITGNYTLDKAKEKALELVKKSALSLGASIEEIEAEIVEESSFNMVRGFYTIGKNMRIKAQVKPGLIQ
>Mature_558_residues
MIIGLDMGGTNIDGVIVEKGKIIKTIKKPTNRDNLFNSIWTALKELLSGYDNTKIERINLSTTVSTNAIVENKLSPVGMI
IQPGPGLPYDFLACGDENVFISGYIDYRGEIIKDFNLFEIENAIKLFKEKNIKAYAVVTKFSIRNPSIEIKIKEILENEI
PNSFVTMGHTISGKLNFPRRVYTSYLNSAVHSIFNEFLNNIKKSLEKEGINAPVFILKADGGTMNISTAEKKPVETILSG
PAASLMGINAMLPTNEDAILLDIGGTTTDIFFLADGVPLFEPWGIRIGKYKTLIRAIYSVSIGLGGDSSICVRNGRIKIG
PQREGVPYAFGGPKPTPTDAMITLELIDENAFSLTQDNVKKAYEAMTLLGKELNLSAKDMAKLILSTMGDIIKNKVDELL
HEINSRPVYTVKELLYGKKIKPKLINIIGGPSKVLAPVLEEKFNLPCYYPKNYSVANAVGAALARPTTEITMLVDTSKKT
LSVPELGLYEKITGNYTLDKAKEKALELVKKSALSLGASIEEIEAEIVEESSFNMVRGFYTIGKNMRIKAQVKPGLIQ

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 61346; Mature: 61346

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLDMGGTNIDGVIVEKGKIIKTIKKPTNRDNLFNSIWTALKELLSGYDNTKIERINL
CEEEEECCCCCCCEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
STTVSTNAIVENKLSPVGMIIQPGPGLPYDFLACGDENVFISGYIDYRGEIIKDFNLFEI
EEEECCCHHHHCCCCCCEEEEECCCCCCCHHEEECCCCEEEEEEECCCCCEECCCCHHHH
ENAIKLFKEKNIKAYAVVTKFSIRNPSIEIKIKEILENEIPNSFVTMGHTISGKLNFPRR
HHHHHHHHHCCCEEEEEEEEEEECCCCEEEEHHHHHHHHCCCCEEECCEEEECCCCCCHH
VYTSYLNSAVHSIFNEFLNNIKKSLEKEGINAPVFILKADGGTMNISTAEKKPVETILSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCHHHHHHCC
PAASLMGINAMLPTNEDAILLDIGGTTTDIFFLADGVPLFEPWGIRIGKYKTLIRAIYSV
CCHHHHCCEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHH
SIGLGGDSSICVRNGRIKIGPQREGVPYAFGGPKPTPTDAMITLELIDENAFSLTQDNVK
EEECCCCCCEEEECCEEEECCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
KAYEAMTLLGKELNLSAKDMAKLILSTMGDIIKNKVDELLHEINSRPVYTVKELLYGKKI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
KPKLINIIGGPSKVLAPVLEEKFNLPCYYPKNYSVANAVGAALARPTTEITMLVDTSKKT
CCHHEEEECCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCE
LSVPELGLYEKITGNYTLDKAKEKALELVKKSALSLGASIEEIEAEIVEESSFNMVRGFY
ECCCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
TIGKNMRIKAQVKPGLIQ
EECCCEEEEEECCCCCCC
>Mature Secondary Structure
MIIGLDMGGTNIDGVIVEKGKIIKTIKKPTNRDNLFNSIWTALKELLSGYDNTKIERINL
CEEEEECCCCCCCEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
STTVSTNAIVENKLSPVGMIIQPGPGLPYDFLACGDENVFISGYIDYRGEIIKDFNLFEI
EEEECCCHHHHCCCCCCEEEEECCCCCCCHHEEECCCCEEEEEEECCCCCEECCCCHHHH
ENAIKLFKEKNIKAYAVVTKFSIRNPSIEIKIKEILENEIPNSFVTMGHTISGKLNFPRR
HHHHHHHHHCCCEEEEEEEEEEECCCCEEEEHHHHHHHHCCCCEEECCEEEECCCCCCHH
VYTSYLNSAVHSIFNEFLNNIKKSLEKEGINAPVFILKADGGTMNISTAEKKPVETILSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCHHHHHHCC
PAASLMGINAMLPTNEDAILLDIGGTTTDIFFLADGVPLFEPWGIRIGKYKTLIRAIYSV
CCHHHHCCEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHH
SIGLGGDSSICVRNGRIKIGPQREGVPYAFGGPKPTPTDAMITLELIDENAFSLTQDNVK
EEECCCCCCEEEECCEEEECCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
KAYEAMTLLGKELNLSAKDMAKLILSTMGDIIKNKVDELLHEINSRPVYTVKELLYGKKI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
KPKLINIIGGPSKVLAPVLEEKFNLPCYYPKNYSVANAVGAALARPTTEITMLVDTSKKT
CCHHEEEECCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCE
LSVPELGLYEKITGNYTLDKAKEKALELVKKSALSLGASIEEIEAEIVEESSFNMVRGFY
ECCCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
TIGKNMRIKAQVKPGLIQ
EECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]