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The map label for this gene is yegE [H]

Identifier: 20807566

GI number: 20807566

Start: 1101447

End: 1103459

Strand: Direct

Name: yegE [H]

Synonym: TTE1100

Alternate gene names: 20807566

Gene position: 1101447-1103459 (Clockwise)

Preceding gene: 20807565

Following gene: 20807567

Centisome position: 40.95

GC content: 39.05

Gene sequence:

>2013_bases
ATGATGAATGCTTTTTACCTGAAGAAGGTCCTCATTGTAGAAGATAGCAGGCTCAATGCGCAGATAACAGCGGATATTCT
GACCAGGCATGGATACGAAACAGAGATAGTCACATCAGGCGAAGAGGCTGTTGAAAAAGCACTAAATAACATCAAAAGTC
CGGACTTAATTCTTATGGACATAGAACTTAAAGGAGCAATCGATGGGATAGATGCAGCAAGAATAATTCAACAGCATAAA
GATATCCCAATTCTATTTCTCACTGCCAATGCCAGTAAAGAAATAATGGAAAAAATAAAATCAGTTTCAGCTTATGGGTA
TGTTCTTAAGGGTGTAGATGAGTATGTACTCATATCTCAAATAGAAATGGCTTTTAAGCTCTATGAGGCTAAAATGCAGC
TAAAAAAGAGAGAAGAGCTGTTCCGCAATATGTTTGAAAATCATGACGTAGCAATGATACTTATTGATCCACAAGCCGGA
CGCATCATTGATGCTAACAAAGCTGCCTGCCACTTCTACGGTTATTCCAGAGAAACTATGCTGCAGATGGACATAGAAGC
TGTTATTGGCGTTTCTACCATAGATGGTGGTCAGAGGTGTTCGGAAGCTTTAAAGAAGGGCTGTAATCCCTGCATTTGCT
TCCAACGGTTAGCTAACGGAGAAGAGAAATTAGTAGAAATATATTCATCCCCTGTAGATTATCAAGGAAAAACACTGATG
CATCTGATTGTCTTTGACATCACCGAACAGTGGAAAGCAAAGAGAGAGCTTGAATTTTATAAAAATCTTTTTGAAGACTC
ACTCAATGAAATTTACATATTCCATCCGCAGACACTAAAATTCATCGCAGTAAACCGTGGAGCAAGGGAAAATTTGGGAT
ATACTGAAGAAGAGCTTAAACAAATGACTCCTGTTGACTTAAAGCCAGAGTTTACCTTGCAAAGCTTTAAAGAACTTCTT
GAGCCCCTTTTAAGAGATGAACAGAAGCAAATCGTTTTTGACACAGTGCACCGCAGAAAAGACGGTTCTTTATATCCAGT
AGAAATCCATTTAGAACTTGTAGAGTTTGATAAAGAAAAAGTATTTGTAGCACTTGTGATTGATATAACAGAACGTCGAG
AAATGGAAAAAGAACTGAAGGAAAGGAATGAAATTTTAAGCACCATAATGGAGTCTGCAGGAGATGCCATTATTATGATT
GACGATAACGGTAAAGTAACTTTTTGGAATCCTGCGGCGGAACGCATACTTGGTTATTCAAGAGAAGAAATAATAGGAAA
GGATTTGCACATGTTTATGATACAAGATATGCGACTGTACGAAGCTTATAGAGAAGCATTTAAAAAATTCCGTTTAACCG
GAAAAGGAAGTGTCGTAGGTAAGACAGTTGAGATGAAGACAAGGCACAAAAATGGGCATGAAATTGATGTAGAACTTTCA
CTTTCTGCCGTTAGAATTAAAGATTCATGGCATGCAATAGGAATTATTCGCGACATAAGCGAGCGCAAGAGATTTGAGGA
ACTGCTTTACCGCCAGTCCATTACCGATCCCCTTACAAATATTTACAACAGACGCTTTTTCATGCAGATGCTGGAGCAGG
AAATAGAGCGAGTAAAACGAAATAAAAAGCCCTTTTCACTTATTATGTTTGACCTGGATCACTTCAAAAACGTAAATGAC
CGCTTTGGGCATGCTGCAGGAGATACGGTTCTTAGAAGTGTTGCCAATACAGTAAAAAAGAGGATACGAAAAACAGATTA
CTTTGCACGCTGGGGAGGGGAGGAATTTATAATTCTTCTGCCTGAAACTTCCTTGAATAATGCAGCTGAGCTGGCTGAAG
AACTCAGAAAGAAAATAAGTGAAACAGCGCTGGACGGTATAGGAAAGGTAACAGCCAGCTTTGGTGTGACGGAATATAGA
AATACTGATACTATGGACACAGTTCTTCTAAGAGTGGATGGAGCGCTTTATGAGGCAAAAGGGTCAGGGAGAAATTGTGT
GAAAATCGCGTAA

Upstream 100 bases:

>100_bases
TTATTGCACTTTTCAAGTGAGAAGAGTACAATAGTACTTTGGAAAATAAAAATCATAAATAATTTTTCAAAGATACTTGC
AAAAAGGTTGGAGGTACCAG

Downstream 100 bases:

>100_bases
AACATAAAATCTTTGAAAGGGGGGCAGAAGGGAGAGCTCTTTTATAGAGCCTTGCCTTAAAAACTATGGAGAAAGGGAAA
GAAACCAAAGACATTTTGGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MMNAFYLKKVLIVEDSRLNAQITADILTRHGYETEIVTSGEEAVEKALNNIKSPDLILMDIELKGAIDGIDAARIIQQHK
DIPILFLTANASKEIMEKIKSVSAYGYVLKGVDEYVLISQIEMAFKLYEAKMQLKKREELFRNMFENHDVAMILIDPQAG
RIIDANKAACHFYGYSRETMLQMDIEAVIGVSTIDGGQRCSEALKKGCNPCICFQRLANGEEKLVEIYSSPVDYQGKTLM
HLIVFDITEQWKAKRELEFYKNLFEDSLNEIYIFHPQTLKFIAVNRGARENLGYTEEELKQMTPVDLKPEFTLQSFKELL
EPLLRDEQKQIVFDTVHRRKDGSLYPVEIHLELVEFDKEKVFVALVIDITERREMEKELKERNEILSTIMESAGDAIIMI
DDNGKVTFWNPAAERILGYSREEIIGKDLHMFMIQDMRLYEAYREAFKKFRLTGKGSVVGKTVEMKTRHKNGHEIDVELS
LSAVRIKDSWHAIGIIRDISERKRFEELLYRQSITDPLTNIYNRRFFMQMLEQEIERVKRNKKPFSLIMFDLDHFKNVND
RFGHAAGDTVLRSVANTVKKRIRKTDYFARWGGEEFIILLPETSLNNAAELAEELRKKISETALDGIGKVTASFGVTEYR
NTDTMDTVLLRVDGALYEAKGSGRNCVKIA

Sequences:

>Translated_670_residues
MMNAFYLKKVLIVEDSRLNAQITADILTRHGYETEIVTSGEEAVEKALNNIKSPDLILMDIELKGAIDGIDAARIIQQHK
DIPILFLTANASKEIMEKIKSVSAYGYVLKGVDEYVLISQIEMAFKLYEAKMQLKKREELFRNMFENHDVAMILIDPQAG
RIIDANKAACHFYGYSRETMLQMDIEAVIGVSTIDGGQRCSEALKKGCNPCICFQRLANGEEKLVEIYSSPVDYQGKTLM
HLIVFDITEQWKAKRELEFYKNLFEDSLNEIYIFHPQTLKFIAVNRGARENLGYTEEELKQMTPVDLKPEFTLQSFKELL
EPLLRDEQKQIVFDTVHRRKDGSLYPVEIHLELVEFDKEKVFVALVIDITERREMEKELKERNEILSTIMESAGDAIIMI
DDNGKVTFWNPAAERILGYSREEIIGKDLHMFMIQDMRLYEAYREAFKKFRLTGKGSVVGKTVEMKTRHKNGHEIDVELS
LSAVRIKDSWHAIGIIRDISERKRFEELLYRQSITDPLTNIYNRRFFMQMLEQEIERVKRNKKPFSLIMFDLDHFKNVND
RFGHAAGDTVLRSVANTVKKRIRKTDYFARWGGEEFIILLPETSLNNAAELAEELRKKISETALDGIGKVTASFGVTEYR
NTDTMDTVLLRVDGALYEAKGSGRNCVKIA
>Mature_670_residues
MMNAFYLKKVLIVEDSRLNAQITADILTRHGYETEIVTSGEEAVEKALNNIKSPDLILMDIELKGAIDGIDAARIIQQHK
DIPILFLTANASKEIMEKIKSVSAYGYVLKGVDEYVLISQIEMAFKLYEAKMQLKKREELFRNMFENHDVAMILIDPQAG
RIIDANKAACHFYGYSRETMLQMDIEAVIGVSTIDGGQRCSEALKKGCNPCICFQRLANGEEKLVEIYSSPVDYQGKTLM
HLIVFDITEQWKAKRELEFYKNLFEDSLNEIYIFHPQTLKFIAVNRGARENLGYTEEELKQMTPVDLKPEFTLQSFKELL
EPLLRDEQKQIVFDTVHRRKDGSLYPVEIHLELVEFDKEKVFVALVIDITERREMEKELKERNEILSTIMESAGDAIIMI
DDNGKVTFWNPAAERILGYSREEIIGKDLHMFMIQDMRLYEAYREAFKKFRLTGKGSVVGKTVEMKTRHKNGHEIDVELS
LSAVRIKDSWHAIGIIRDISERKRFEELLYRQSITDPLTNIYNRRFFMQMLEQEIERVKRNKKPFSLIMFDLDHFKNVND
RFGHAAGDTVLRSVANTVKKRIRKTDYFARWGGEEFIILLPETSLNNAAELAEELRKKISETALDGIGKVTASFGVTEYR
NTDTMDTVLLRVDGALYEAKGSGRNCVKIA

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=276, Percent_Identity=32.6086956521739, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788381, Length=578, Percent_Identity=26.1245674740484, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87082007, Length=185, Percent_Identity=38.9189189189189, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=40, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=34.8837209302326, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=31.2101910828025, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=206, Percent_Identity=28.1553398058252, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=35.1190476190476, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787541, Length=300, Percent_Identity=25, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=30.379746835443, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081921, Length=103, Percent_Identity=34.9514563106796, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=32.2981366459627, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787056, Length=159, Percent_Identity=30.8176100628931, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 77226; Mature: 77226

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAFYLKKVLIVEDSRLNAQITADILTRHGYETEIVTSGEEAVEKALNNIKSPDLILMD
CCCHHHHEEEEEEECCCCCCEEEHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEE
IELKGAIDGIDAARIIQQHKDIPILFLTANASKEIMEKIKSVSAYGYVLKGVDEYVLISQ
EEECCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IEMAFKLYEAKMQLKKREELFRNMFENHDVAMILIDPQAGRIIDANKAACHFYGYSRETM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEEEECCCCCHH
LQMDIEAVIGVSTIDGGQRCSEALKKGCNPCICFQRLANGEEKLVEIYSSPVDYQGKTLM
EEEEHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEE
HLIVFDITEQWKAKRELEFYKNLFEDSLNEIYIFHPQTLKFIAVNRGARENLGYTEEELK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHH
QMTPVDLKPEFTLQSFKELLEPLLRDEQKQIVFDTVHRRKDGSLYPVEIHLELVEFDKEK
HCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCE
VFVALVIDITERREMEKELKERNEILSTIMESAGDAIIMIDDNGKVTFWNPAAERILGYS
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECHHHHHHHCCC
REEIIGKDLHMFMIQDMRLYEAYREAFKKFRLTGKGSVVGKTVEMKTRHKNGHEIDVELS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEEE
LSAVRIKDSWHAIGIIRDISERKRFEELLYRQSITDPLTNIYNRRFFMQMLEQEIERVKR
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NKKPFSLIMFDLDHFKNVNDRFGHAAGDTVLRSVANTVKKRIRKTDYFARWGGEEFIILL
CCCCEEEEEEEHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PETSLNNAAELAEELRKKISETALDGIGKVTASFGVTEYRNTDTMDTVLLRVDGALYEAK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEECCCEEECC
GSGRNCVKIA
CCCCCEEEEC
>Mature Secondary Structure
MMNAFYLKKVLIVEDSRLNAQITADILTRHGYETEIVTSGEEAVEKALNNIKSPDLILMD
CCCHHHHEEEEEEECCCCCCEEEHHHHHCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEE
IELKGAIDGIDAARIIQQHKDIPILFLTANASKEIMEKIKSVSAYGYVLKGVDEYVLISQ
EEECCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IEMAFKLYEAKMQLKKREELFRNMFENHDVAMILIDPQAGRIIDANKAACHFYGYSRETM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEEEECCCCCHH
LQMDIEAVIGVSTIDGGQRCSEALKKGCNPCICFQRLANGEEKLVEIYSSPVDYQGKTLM
EEEEHHHHEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEE
HLIVFDITEQWKAKRELEFYKNLFEDSLNEIYIFHPQTLKFIAVNRGARENLGYTEEELK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHH
QMTPVDLKPEFTLQSFKELLEPLLRDEQKQIVFDTVHRRKDGSLYPVEIHLELVEFDKEK
HCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCE
VFVALVIDITERREMEKELKERNEILSTIMESAGDAIIMIDDNGKVTFWNPAAERILGYS
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECHHHHHHHCCC
REEIIGKDLHMFMIQDMRLYEAYREAFKKFRLTGKGSVVGKTVEMKTRHKNGHEIDVELS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEEE
LSAVRIKDSWHAIGIIRDISERKRFEELLYRQSITDPLTNIYNRRFFMQMLEQEIERVKR
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NKKPFSLIMFDLDHFKNVNDRFGHAAGDTVLRSVANTVKKRIRKTDYFARWGGEEFIILL
CCCCEEEEEEEHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PETSLNNAAELAEELRKKISETALDGIGKVTASFGVTEYRNTDTMDTVLLRVDGALYEAK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEECCCEEECC
GSGRNCVKIA
CCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]