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The map label for this gene is CheA [H]

Identifier: 20807518

GI number: 20807518

Start: 1044584

End: 1046995

Strand: Direct

Name: CheA [H]

Synonym: TTE1039

Alternate gene names: 20807518

Gene position: 1044584-1046995 (Clockwise)

Preceding gene: 20807517

Following gene: 20807519

Centisome position: 38.84

GC content: 35.74

Gene sequence:

>2412_bases
ATGAAGAATGAATCCAATGGATTTATAAAGAATGCAAAAAAATTGCTTGACAATATAGGCTTTTTTGTGCTTGGGTTAGA
AGATGCTTATGAGAAAGATAAAGCAGCTGAAGAAATTTTAAGCAGATTGAGTGAGTTATTGCAATTATGCAAGTCCTATG
ATTTTAATAAACTGAGTTCTTTTATAGAAAGTTTAATAAAACTGATTAAGGAAATAGCACAAAAAGAGAAATTTCTCGAT
ACGGAGATAAGTGATTTTTTACTGGATTCTTTTGAGAGGATAATAAGTTTAGTTGAAAACGCTGAAAAAGAAGGACTTGA
GACATTAAAAGCGCCGGAGCTAAAAGAATTTGAAGGCAGAATATCAGAGTTTTTGGATGAAATGGATAAAATGCCTCAAG
CTTCTGTGATACATACAGACGACATGTTACGCACTATTTCCAAAGACAAAAAGATTTTTTTAAATGAATTAATACAAAAA
AGCGAAAATGTTTATGAAATACTACTTCAAGTAGTAGGTACAAAAGCTGTAGAAATTGATGTAACGGAATTTTTTGACAA
ATTAAAAGAAATTGGAGAGGTTACACATATTGATGCTGATACGCGAAAATTACCTTTACTAGAAGAGCTTGATCCTTCTA
TCCCTTATATATCTTTGACTTTTGTATTGATATCTGATAAAAATGCCCAAGAAATAGAAGATACACTGTATAAAGTAATA
GGAACAGATACTGATGTAAAGGTACTTGTGTCACCGGTATTTCCTGATGCAATTGAAAAATTTACGACATCGAAAGGCGA
TTCTTTATCAGCTATGTCGGCTGGAGAAGACAAGGTACAAGAAGTCATGGATATGATAATTTCACAGCAGGAGGAGTTCT
ATAAGATTGCAGAGACGCCAGAAGACCGGCGCTGGAGAGGAAACATGGTTATAAATGTGCTTCAAAGGATAGCAGAATAC
ATGGGTTGGGTTACAAAAAGTGGAAATTTAGTTAAAATGATTAAAACAAACAAAATCAAATTACCAGAAAGATTTGTAAA
TCTTGTGAATCTTATAATAAACAACGACAAAAAATTGCAGGAAAATGAGTCTAAAGATAGGGGAGTTTATGCAGCAAGAA
CTGAGAATGAAGAAATAGAAAGGCGTGAAATTAAACAAGGTGAAGAGAAAATCTTGCAAGAGTATAATGAAAGTATTTCC
AGAGATATGACGAACAATAAAGGTTTTTCAGAAATCGAAACTACGAAGACGCTGAAAGTAGACCAGACTAAAATCGATGA
GCTTATGAAGTTAGTAGGAGAACTGGTTGCAGTCAATAATGGACTTTCGTTTATGATAAAAAAAATCGAAATGGAATATG
GATCAACAGATGTAACAAAAGAATTAAAAGATAAGCAGGTTTTGTTAAAGAGGATAGGAAATGACTTACAGGACATAGTA
ATGAGCTTGAGACTTCTTCCAATAAAATATATATTTGATCGTTTTCCCAGAATGATTCGCGAGATTAGCAGAAAACTTGA
CAAGAAGGTACGTCTTGTTACCGAGGGGGAGGAAACCCAGATAGACAAGAATATTGTAACGGCGCTTTATGATCCAATGT
TACACATTATAAGGAATGCAATCGATCACGGAATTGAGAAACCAGAAGAACGGTTAAAAAAGGGAAAATCCGAAGAAGGT
TTGTTGGTTCTAAAGGCACAAAAAATAGGAGATAAGGTTATTATTGAGGTCAGAGATGATGGACGTGGCATCGATACTGA
GGTAGTAAAAGCGAAGGCAGTTCAAAAAGGTTTTGTATCTGCTGAAAAAGGAGCGACGATGGATGAACACGCTGTTTTGG
AACTTCTGTTTATACCTGGTTTTAGTACTTCAGATGACGTAACGGAGTTGTCTGGTAGAGGTGTGGGAATGGATGTCGTG
CGTGATACAGTGAGAAGACTGGGTGGTAATGTGCGTTTGATGAGTAAAGCGGGAGTAGGTACTTCTGTATACCTGGAACT
GCCTGTGACAATGGTAACATCCAGGGTGCTGTTATTTACTTTGAAAGAGCGCCGTTATGCCTTGCCCCTTGAAAGTGTAG
GAGAACTAGTAAAAATAAAGGCTGAGGATATAAGAAAGATGAAAGGAAAAGAAGTAGTAGTATTGAGGGGAGAAATAATG
CCACTTTTGAGACTAAAGGAATTTATGGGACTTCAAAATGATGCGGAAGAAAAATTTGATACAGAATATTCACTTGTTGT
ACTAAATAATGGCGTGGCGGTGATGGTAGATGAATTTATTGGTGAGCAGGAGATCATTATAAGGCCACTTCCGGAGGAAC
TATCTTCAGTATATTTTTTGGGTGCGGCTATATTGGGAGATGGGGATATTGTTCTTGTTCTAAATCCTGAAAAATTAGGA
GGAGGCATTTAA

Upstream 100 bases:

>100_bases
TTCGAGTTGGGGCAAATCTTTATTTAGAAAAACCGGTTGATCCGATATGCTTGCAACTTTCTGCAAAAATGCTTACAGGG
ATAAGGTAGGGATGACTGAA

Downstream 100 bases:

>100_bases
AGTGATGTTGGACTATCTTGATGCCTATGTTGAGGAGACGGAAGAACAGCTTTCAAGATTGGAACAGCTTTTTTTGGAAA
TAGAGAAAAATACCAACCAA

Product: chemotaxis protein histidine kinase-like kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 803

Protein sequence:

>803_residues
MKNESNGFIKNAKKLLDNIGFFVLGLEDAYEKDKAAEEILSRLSELLQLCKSYDFNKLSSFIESLIKLIKEIAQKEKFLD
TEISDFLLDSFERIISLVENAEKEGLETLKAPELKEFEGRISEFLDEMDKMPQASVIHTDDMLRTISKDKKIFLNELIQK
SENVYEILLQVVGTKAVEIDVTEFFDKLKEIGEVTHIDADTRKLPLLEELDPSIPYISLTFVLISDKNAQEIEDTLYKVI
GTDTDVKVLVSPVFPDAIEKFTTSKGDSLSAMSAGEDKVQEVMDMIISQQEEFYKIAETPEDRRWRGNMVINVLQRIAEY
MGWVTKSGNLVKMIKTNKIKLPERFVNLVNLIINNDKKLQENESKDRGVYAARTENEEIERREIKQGEEKILQEYNESIS
RDMTNNKGFSEIETTKTLKVDQTKIDELMKLVGELVAVNNGLSFMIKKIEMEYGSTDVTKELKDKQVLLKRIGNDLQDIV
MSLRLLPIKYIFDRFPRMIREISRKLDKKVRLVTEGEETQIDKNIVTALYDPMLHIIRNAIDHGIEKPEERLKKGKSEEG
LLVLKAQKIGDKVIIEVRDDGRGIDTEVVKAKAVQKGFVSAEKGATMDEHAVLELLFIPGFSTSDDVTELSGRGVGMDVV
RDTVRRLGGNVRLMSKAGVGTSVYLELPVTMVTSRVLLFTLKERRYALPLESVGELVKIKAEDIRKMKGKEVVVLRGEIM
PLLRLKEFMGLQNDAEEKFDTEYSLVVLNNGVAVMVDEFIGEQEIIIRPLPEELSSVYFLGAAILGDGDIVLVLNPEKLG
GGI

Sequences:

>Translated_803_residues
MKNESNGFIKNAKKLLDNIGFFVLGLEDAYEKDKAAEEILSRLSELLQLCKSYDFNKLSSFIESLIKLIKEIAQKEKFLD
TEISDFLLDSFERIISLVENAEKEGLETLKAPELKEFEGRISEFLDEMDKMPQASVIHTDDMLRTISKDKKIFLNELIQK
SENVYEILLQVVGTKAVEIDVTEFFDKLKEIGEVTHIDADTRKLPLLEELDPSIPYISLTFVLISDKNAQEIEDTLYKVI
GTDTDVKVLVSPVFPDAIEKFTTSKGDSLSAMSAGEDKVQEVMDMIISQQEEFYKIAETPEDRRWRGNMVINVLQRIAEY
MGWVTKSGNLVKMIKTNKIKLPERFVNLVNLIINNDKKLQENESKDRGVYAARTENEEIERREIKQGEEKILQEYNESIS
RDMTNNKGFSEIETTKTLKVDQTKIDELMKLVGELVAVNNGLSFMIKKIEMEYGSTDVTKELKDKQVLLKRIGNDLQDIV
MSLRLLPIKYIFDRFPRMIREISRKLDKKVRLVTEGEETQIDKNIVTALYDPMLHIIRNAIDHGIEKPEERLKKGKSEEG
LLVLKAQKIGDKVIIEVRDDGRGIDTEVVKAKAVQKGFVSAEKGATMDEHAVLELLFIPGFSTSDDVTELSGRGVGMDVV
RDTVRRLGGNVRLMSKAGVGTSVYLELPVTMVTSRVLLFTLKERRYALPLESVGELVKIKAEDIRKMKGKEVVVLRGEIM
PLLRLKEFMGLQNDAEEKFDTEYSLVVLNNGVAVMVDEFIGEQEIIIRPLPEELSSVYFLGAAILGDGDIVLVLNPEKLG
GGI
>Mature_803_residues
MKNESNGFIKNAKKLLDNIGFFVLGLEDAYEKDKAAEEILSRLSELLQLCKSYDFNKLSSFIESLIKLIKEIAQKEKFLD
TEISDFLLDSFERIISLVENAEKEGLETLKAPELKEFEGRISEFLDEMDKMPQASVIHTDDMLRTISKDKKIFLNELIQK
SENVYEILLQVVGTKAVEIDVTEFFDKLKEIGEVTHIDADTRKLPLLEELDPSIPYISLTFVLISDKNAQEIEDTLYKVI
GTDTDVKVLVSPVFPDAIEKFTTSKGDSLSAMSAGEDKVQEVMDMIISQQEEFYKIAETPEDRRWRGNMVINVLQRIAEY
MGWVTKSGNLVKMIKTNKIKLPERFVNLVNLIINNDKKLQENESKDRGVYAARTENEEIERREIKQGEEKILQEYNESIS
RDMTNNKGFSEIETTKTLKVDQTKIDELMKLVGELVAVNNGLSFMIKKIEMEYGSTDVTKELKDKQVLLKRIGNDLQDIV
MSLRLLPIKYIFDRFPRMIREISRKLDKKVRLVTEGEETQIDKNIVTALYDPMLHIIRNAIDHGIEKPEERLKKGKSEEG
LLVLKAQKIGDKVIIEVRDDGRGIDTEVVKAKAVQKGFVSAEKGATMDEHAVLELLFIPGFSTSDDVTELSGRGVGMDVV
RDTVRRLGGNVRLMSKAGVGTSVYLELPVTMVTSRVLLFTLKERRYALPLESVGELVKIKAEDIRKMKGKEVVVLRGEIM
PLLRLKEFMGLQNDAEEKFDTEYSLVVLNNGVAVMVDEFIGEQEIIIRPLPEELSSVYFLGAAILGDGDIVLVLNPEKLG
GGI

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=391, Percent_Identity=35.5498721227622, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91075; Mature: 91075

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50851 CHEW ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNESNGFIKNAKKLLDNIGFFVLGLEDAYEKDKAAEEILSRLSELLQLCKSYDFNKLSS
CCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIESLIKLIKEIAQKEKFLDTEISDFLLDSFERIISLVENAEKEGLETLKAPELKEFEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ISEFLDEMDKMPQASVIHTDDMLRTISKDKKIFLNELIQKSENVYEILLQVVGTKAVEID
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEE
VTEFFDKLKEIGEVTHIDADTRKLPLLEELDPSIPYISLTFVLISDKNAQEIEDTLYKVI
HHHHHHHHHHHHHHEECCCCCCCCCCHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHH
GTDTDVKVLVSPVFPDAIEKFTTSKGDSLSAMSAGEDKVQEVMDMIISQQEEFYKIAETP
CCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHCHHHHHHHHCCC
EDRRWRGNMVINVLQRIAEYMGWVTKSGNLVKMIKTNKIKLPERFVNLVNLIINNDKKLQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHH
ENESKDRGVYAARTENEEIERREIKQGEEKILQEYNESISRDMTNNKGFSEIETTKTLKV
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCEEC
DQTKIDELMKLVGELVAVNNGLSFMIKKIEMEYGSTDVTKELKDKQVLLKRIGNDLQDIV
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
MSLRLLPIKYIFDRFPRMIREISRKLDKKVRLVTEGEETQIDKNIVTALYDPMLHIIRNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IDHGIEKPEERLKKGKSEEGLLVLKAQKIGDKVIIEVRDDGRGIDTEVVKAKAVQKGFVS
HHHCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AEKGATMDEHAVLELLFIPGFSTSDDVTELSGRGVGMDVVRDTVRRLGGNVRLMSKAGVG
CCCCCCCCHHHHHHEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TSVYLELPVTMVTSRVLLFTLKERRYALPLESVGELVKIKAEDIRKMKGKEVVVLRGEIM
EEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHH
PLLRLKEFMGLQNDAEEKFDTEYSLVVLNNGVAVMVDEFIGEQEIIIRPLPEELSSVYFL
HHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCEEEEHHHCCCCCEEEECCCHHHHHHHHH
GAAILGDGDIVLVLNPEKLGGGI
HHHEECCCCEEEEECCHHCCCCC
>Mature Secondary Structure
MKNESNGFIKNAKKLLDNIGFFVLGLEDAYEKDKAAEEILSRLSELLQLCKSYDFNKLSS
CCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIESLIKLIKEIAQKEKFLDTEISDFLLDSFERIISLVENAEKEGLETLKAPELKEFEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ISEFLDEMDKMPQASVIHTDDMLRTISKDKKIFLNELIQKSENVYEILLQVVGTKAVEID
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEE
VTEFFDKLKEIGEVTHIDADTRKLPLLEELDPSIPYISLTFVLISDKNAQEIEDTLYKVI
HHHHHHHHHHHHHHEECCCCCCCCCCHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHH
GTDTDVKVLVSPVFPDAIEKFTTSKGDSLSAMSAGEDKVQEVMDMIISQQEEFYKIAETP
CCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHCHHHHHHHHCCC
EDRRWRGNMVINVLQRIAEYMGWVTKSGNLVKMIKTNKIKLPERFVNLVNLIINNDKKLQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHH
ENESKDRGVYAARTENEEIERREIKQGEEKILQEYNESISRDMTNNKGFSEIETTKTLKV
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCEEC
DQTKIDELMKLVGELVAVNNGLSFMIKKIEMEYGSTDVTKELKDKQVLLKRIGNDLQDIV
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
MSLRLLPIKYIFDRFPRMIREISRKLDKKVRLVTEGEETQIDKNIVTALYDPMLHIIRNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IDHGIEKPEERLKKGKSEEGLLVLKAQKIGDKVIIEVRDDGRGIDTEVVKAKAVQKGFVS
HHHCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AEKGATMDEHAVLELLFIPGFSTSDDVTELSGRGVGMDVVRDTVRRLGGNVRLMSKAGVG
CCCCCCCCHHHHHHEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TSVYLELPVTMVTSRVLLFTLKERRYALPLESVGELVKIKAEDIRKMKGKEVVVLRGEIM
EEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHH
PLLRLKEFMGLQNDAEEKFDTEYSLVVLNNGVAVMVDEFIGEQEIIIRPLPEELSSVYFL
HHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCEEEEHHHCCCCCEEEECCCHHHHHHHHH
GAAILGDGDIVLVLNPEKLGGGI
HHHEECCCCEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]