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The map label for this gene is AroA [H]

Identifier: 20807493

GI number: 20807493

Start: 1015406

End: 1016422

Strand: Direct

Name: AroA [H]

Synonym: TTE1013

Alternate gene names: 20807493

Gene position: 1015406-1016422 (Clockwise)

Preceding gene: 20807492

Following gene: 20807494

Centisome position: 37.76

GC content: 43.36

Gene sequence:

>1017_bases
ATGGTAATTGTAATGAATATAGATGCTAGTGAGAAACAAATTTCCGAGATTACAAATCTTTTAACTTCTCTCGGGCTGGG
TTATCACATTTCAAGAGGGGAAGAAAAAATAGTAATAGGTGTGATAGGGGATAAAAGGAAACTTGATGGAAAAGCGATAG
AGATGATGGAAGGAGTAGAGAAAGTAATTCCAATAGTCGACCCTTATAAGCTAGCTAGCAGGATATTCAAACCAGAGCCT
ACTATTGTAAAAGTTGGCGATATTGAAATAGGAGGCAAAAATATTGTCATAATGGCAGGACCTTGTGCTGTAGAGAGCCG
AGAACAGCTTTTTGAGAGTGCTATGGCAGTGAAAAGGGCGGGAGCTCACTTTTTAAGGGGAGGGGCATATAAACCCAGGA
CCTCGCCTTACTCTTTCCAAGGGTTAGAGGAGGAAGGATTAAAAATGCTCAGTGAAGCGAGAGAGCTTACGGGTCTTAAA
ATTGTCACGGAAGTGATGGACGTGCATTCAGTGGAAAAAGTTGCGGAGTATGCGGATGTCCTTCAAATTGGAGCAAGAAA
CATGCAGAATTTCTCACTTCTTAAGGCGGTAGGGAGGATGAATAAGCCTGTACTTTTAAAAAGGGGGCTTGCCGCGACTT
TGGAGGAGTGGTTGAGCGCTGCAGAGTACATCTTAAATGAGGGAAATAAGGATGTAATTCTCTGCGAAAGAGGTATAAGG
ACTTTTGAGACTTATACCCGCAATACTTTAGATTTGAGTGCGGTTCCAGCCATAAAAAAACTGAGTCATCTACCTATAAT
AGTAGACCCCAGCCATGGAACTGGTCGGTGGCACCTTGTGCCTTCCATGGCCAAAGCGGCTGTTGCTGCAGGAGCGGATG
GACTTATCATAGAAGTGCATCCTGACCCTAAAAATGCTCTTTCTGATGGGCCTCAATCTTTGACCCCAGACAACTTTGAA
AGCTTGGTGAAAGAATTAAAAATTATTGCTGAAGCTGTAGGGCGGGAACTGGCATGA

Upstream 100 bases:

>100_bases
AAAGAGGCTTTGGAAGATCTGAAGATAAAGGCAGATTTTTTGAAAGTGATAGGTTCTTATCCAAAGTTCAAGATGGGAAA
ATAAAGGGAGGAGAAGAGGT

Downstream 100 bases:

>100_bases
TAGAGAAGGTAGCTGTTGTGGGACTGGGCCTTATAGGCGGGTCTATCGCAAAAGCTTTAAGAAAGTATACAGATATAGAT
GTTGTCGGGGTGGATATTGA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVIVMNIDASEKQISEITNLLTSLGLGYHISRGEEKIVIGVIGDKRKLDGKAIEMMEGVEKVIPIVDPYKLASRIFKPEP
TIVKVGDIEIGGKNIVIMAGPCAVESREQLFESAMAVKRAGAHFLRGGAYKPRTSPYSFQGLEEEGLKMLSEARELTGLK
IVTEVMDVHSVEKVAEYADVLQIGARNMQNFSLLKAVGRMNKPVLLKRGLAATLEEWLSAAEYILNEGNKDVILCERGIR
TFETYTRNTLDLSAVPAIKKLSHLPIIVDPSHGTGRWHLVPSMAKAAVAAGADGLIIEVHPDPKNALSDGPQSLTPDNFE
SLVKELKIIAEAVGRELA

Sequences:

>Translated_338_residues
MVIVMNIDASEKQISEITNLLTSLGLGYHISRGEEKIVIGVIGDKRKLDGKAIEMMEGVEKVIPIVDPYKLASRIFKPEP
TIVKVGDIEIGGKNIVIMAGPCAVESREQLFESAMAVKRAGAHFLRGGAYKPRTSPYSFQGLEEEGLKMLSEARELTGLK
IVTEVMDVHSVEKVAEYADVLQIGARNMQNFSLLKAVGRMNKPVLLKRGLAATLEEWLSAAEYILNEGNKDVILCERGIR
TFETYTRNTLDLSAVPAIKKLSHLPIIVDPSHGTGRWHLVPSMAKAAVAAGADGLIIEVHPDPKNALSDGPQSLTPDNFE
SLVKELKIIAEAVGRELA
>Mature_338_residues
MVIVMNIDASEKQISEITNLLTSLGLGYHISRGEEKIVIGVIGDKRKLDGKAIEMMEGVEKVIPIVDPYKLASRIFKPEP
TIVKVGDIEIGGKNIVIMAGPCAVESREQLFESAMAVKRAGAHFLRGGAYKPRTSPYSFQGLEEEGLKMLSEARELTGLK
IVTEVMDVHSVEKVAEYADVLQIGARNMQNFSLLKAVGRMNKPVLLKRGLAATLEEWLSAAEYILNEGNKDVILCERGIR
TFETYTRNTLDLSAVPAIKKLSHLPIIVDPSHGTGRWHLVPSMAKAAVAAGADGLIIEVHPDPKNALSDGPQSLTPDNFE
SLVKELKIIAEAVGRELA

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=272, Percent_Identity=28.3088235294118, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36829; Mature: 36829

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVMNIDASEKQISEITNLLTSLGLGYHISRGEEKIVIGVIGDKRKLDGKAIEMMEGVE
CEEEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHH
KVIPIVDPYKLASRIFKPEPTIVKVGDIEIGGKNIVIMAGPCAVESREQLFESAMAVKRA
HHCCCCCHHHHHHHHCCCCCCEEEECCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHH
GAHFLRGGAYKPRTSPYSFQGLEEEGLKMLSEARELTGLKIVTEVMDVHSVEKVAEYADV
CHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQIGARNMQNFSLLKAVGRMNKPVLLKRGLAATLEEWLSAAEYILNEGNKDVILCERGIR
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCH
TFETYTRNTLDLSAVPAIKKLSHLPIIVDPSHGTGRWHLVPSMAKAAVAAGADGLIIEVH
HHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEECHHHHHHHHHCCCCCEEEEEC
PDPKNALSDGPQSLTPDNFESLVKELKIIAEAVGRELA
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVIVMNIDASEKQISEITNLLTSLGLGYHISRGEEKIVIGVIGDKRKLDGKAIEMMEGVE
CEEEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHH
KVIPIVDPYKLASRIFKPEPTIVKVGDIEIGGKNIVIMAGPCAVESREQLFESAMAVKRA
HHCCCCCHHHHHHHHCCCCCCEEEECCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHH
GAHFLRGGAYKPRTSPYSFQGLEEEGLKMLSEARELTGLKIVTEVMDVHSVEKVAEYADV
CHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQIGARNMQNFSLLKAVGRMNKPVLLKRGLAATLEEWLSAAEYILNEGNKDVILCERGIR
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCH
TFETYTRNTLDLSAVPAIKKLSHLPIIVDPSHGTGRWHLVPSMAKAAVAAGADGLIIEVH
HHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEECHHHHHHHHHCCCCCEEEEEC
PDPKNALSDGPQSLTPDNFESLVKELKIIAEAVGRELA
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]