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The map label for this gene is DeoC

Identifier: 20807455

GI number: 20807455

Start: 977546

End: 978241

Strand: Direct

Name: DeoC

Synonym: TTE0975

Alternate gene names: 20807455

Gene position: 977546-978241 (Clockwise)

Preceding gene: 20807454

Following gene: 20807456

Centisome position: 36.35

GC content: 41.52

Gene sequence:

>696_bases
ATGTTGAAAAAGGAGGAATCTTTAATGAACATAGCTAAGATGATAGACCACACTCTTTTAAAGCCAAATGCCACAAAAGA
AGAGATAAAAAAGGTCTGCGAAGAGGCGAGGGAATACGGATTTGCTTCAGTGTGCATAAATCCATGTTTTGTTGATTTGG
CCTATGAGATGCTAAAGGATACTGATGTGAAGGTATGCACGGTTGTAGGTTTCCCTCTGGGAGCTAATACAATTGAGACA
AAAGTGGTTGAGGCAGTGGAAGCGGTTAAAAAGGGAGCTACTGAGATAGATATGGTGCTTAATATAAGCATGCTGAAAAG
TGGCGAATATGACTATGTGAAGAAAGAAATAGGGGAAGTAGTAAAGGCTGTGAAATCCCACGGGGACATAGTTGTGAAAG
TGATACTGGAGACTTGCTATTTATCTGATGAGGAGAAAATCAAAGCCTGTGAGATTTCAAAGGAAGCAGGCGCTGATTTT
GTAAAAACTTCTACAGGCTTTGGGCCGGGAGGTGCTACAGTAGAAGATGTGAAGCTCATGAGAAAAGTGGTTGGAGAGAA
TTTTGGAGTAAAAGCTTCCGGCGGAATAAGAAGCTATGAAGATGCAAAAGCGATGATAGAAGCAGGGGCTAACAGGATTG
GAGCTAGTGCGGGTGTTAAAATAGTAGAGGAGTGGAAAAAACAAGGTTTAGGTTGA

Upstream 100 bases:

>100_bases
TAAAGTGAGGAAAGGCTGGAGGGACAATGAGAAGCTTCTCAGGAAATTGGGCTATGCCATTGACAAGTAAGCTTTTAGAG
TAGTAAATTATAGGAGAAAG

Downstream 100 bases:

>100_bases
TAAAAATGCGCTTTTTAAAAACAGAGGCAATAGTTTTAAAGAGCAATTTGATAAGCGAGAAGGATAAAATTGCTACTCTT
TTCACCAGAGATTACGGGAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKDTDVKVCTVVGFPLGANTIET
KVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEVVKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADF
VKTSTGFGPGGATVEDVKLMRKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG

Sequences:

>Translated_231_residues
MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKDTDVKVCTVVGFPLGANTIET
KVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEVVKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADF
VKTSTGFGPGGATVEDVKLMRKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG
>Mature_231_residues
MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKDTDVKVCTVVGFPLGANTIET
KVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEVVKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADF
VKTSTGFGPGGATVEDVKLMRKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1790841, Length=226, Percent_Identity=32.7433628318584, Blast_Score=104, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19922098, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_THETN (Q8RB49)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622626.1
- ProteinModelPortal:   Q8RB49
- SMR:   Q8RB49
- GeneID:   995824
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0975
- NMPDR:   fig|273068.3.peg.398
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   TTEN273068:TTE0975-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 25008; Mature: 25008

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 162-162 ACT_SITE 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKD
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
TDVKVCTVVGFPLGANTIETKVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEV
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADFVKTSTGFGPGGATVEDVKLM
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCHHHCCCCCCCCCCCHHHHHHH
RKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKD
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
TDVKVCTVVGFPLGANTIETKVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEV
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADFVKTSTGFGPGGATVEDVKLM
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCHHHCCCCCCCCCCCHHHHHHH
RKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336