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The map label for this gene is FtsW [H]

Identifier: 20807386

GI number: 20807386

Start: 913518

End: 914615

Strand: Direct

Name: FtsW [H]

Synonym: TTE0905

Alternate gene names: 20807386

Gene position: 913518-914615 (Clockwise)

Preceding gene: 20807385

Following gene: 20807387

Centisome position: 33.97

GC content: 39.34

Gene sequence:

>1098_bases
GTGTTTGATAAAAAGCTTCTTAAAAATTTTGATTGGGGGCTTTTAATTGTGGTTTTATTAATTTCTATATACAGTCTCAT
AGTTATCACAAGTGCATCTCATGCTCTGCAGACAGGTTCATATAAAAAAGTGATAGTGCAAGCTGTGGCAATTTTGATAG
GACTTATTTCAATTGCATTTATATGCCTTTTTGACTACAATGTACTGGCTAAATTTTCCACATTTATATATATTTTAAAC
TTAATTGGCTTGGCGCTGGTATTAGTGATAGGTAAGGTCAGCAATGGGGCACAGAGCTGGATAAGCCTTGGACCTGTTGA
TATACAGCCTTCAGAGTTTTCTAAGTTAGCCTTGGTGCTTACTTTAGCTAACATGTTCAGCAATCAGGAAGAAATCAAAT
CTTTCAGAGAGCTCATAGGCCCTCTTGTATATGTAGGAATTCCTTTTATTGCTGTGATGTTGCAACCTGATTTGGGGACG
GGGCTTGTCTTTATAGCAATTTTTTTAGCAATTGTATATATATCTGGAATAAGGACTAAAGTGCTCGCGCAACTTTTTGC
AATAGGAATTGCAATGCTGCCTATTGGATACAAACTCTTAAAGCCCTATCAGAGAAATCGCCTTTTGTCCTTTTTAAACC
CCGAATTGGACCCAATGGGGACAGGCTATCACGTGATACAGTCAAAGATAGCAGTAGGTTCAGGGATGTTCTGGGGGAAA
GGACTTTTTCACGGCAGCCAGACCCAGCTTTATTACCTTCCAGAGGCTTGGACAGACTTTATCTTTTCTGTTGTTGGGGA
GGAATTAGGATTCGTAGGTGCTACTTTTCTTATAATCCTTTACGCCATAATGCTTTATAAAGCCTGGAAAATTGCGTATA
ATGCCAAGGACAAGTACGGAATGCTTGTGGCAGTCGGGATAATTGCCATGTTCACCTTTCACATATTTGAAAATATAGGC
ATGACAATTGGACTTATGCCAATCACCGGTATTCCTCTTCCTTTTATGAGCTATGGGGGAAGTGCTATGGTAGTGGACAT
GATGGCGATAGGGCTTTTAGAGAGTATCAGCATGAGAAGGCAGAAAATAAACTTCTGA

Upstream 100 bases:

>100_bases
GTGATAAGGTAAACTGGCGACCAGCCAGTTTTTTTATGTAGTTAAAACTTTTATTGTATGGTATAATACAAATTGGATTT
TTTAAGAAGGGAGAATAGCT

Downstream 100 bases:

>100_bases
GGGGGGCATTTTTATGAATATCGCTCTTATTGCGCATGACCAGAAGAAAGAACTTATGGTTAACTTTGCTATCGCTTATA
AGCACATATTTGAAAAATGC

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MFDKKLLKNFDWGLLIVVLLISIYSLIVITSASHALQTGSYKKVIVQAVAILIGLISIAFICLFDYNVLAKFSTFIYILN
LIGLALVLVIGKVSNGAQSWISLGPVDIQPSEFSKLALVLTLANMFSNQEEIKSFRELIGPLVYVGIPFIAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFAIGIAMLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAVGSGMFWGK
GLFHGSQTQLYYLPEAWTDFIFSVVGEELGFVGATFLIILYAIMLYKAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGLMPITGIPLPFMSYGGSAMVVDMMAIGLLESISMRRQKINF

Sequences:

>Translated_365_residues
MFDKKLLKNFDWGLLIVVLLISIYSLIVITSASHALQTGSYKKVIVQAVAILIGLISIAFICLFDYNVLAKFSTFIYILN
LIGLALVLVIGKVSNGAQSWISLGPVDIQPSEFSKLALVLTLANMFSNQEEIKSFRELIGPLVYVGIPFIAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFAIGIAMLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAVGSGMFWGK
GLFHGSQTQLYYLPEAWTDFIFSVVGEELGFVGATFLIILYAIMLYKAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGLMPITGIPLPFMSYGGSAMVVDMMAIGLLESISMRRQKINF
>Mature_365_residues
MFDKKLLKNFDWGLLIVVLLISIYSLIVITSASHALQTGSYKKVIVQAVAILIGLISIAFICLFDYNVLAKFSTFIYILN
LIGLALVLVIGKVSNGAQSWISLGPVDIQPSEFSKLALVLTLANMFSNQEEIKSFRELIGPLVYVGIPFIAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFAIGIAMLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAVGSGMFWGK
GLFHGSQTQLYYLPEAWTDFIFSVVGEELGFVGATFLIILYAIMLYKAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGLMPITGIPLPFMSYGGSAMVVDMMAIGLLESISMRRQKINF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=38.1924198250729, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=31.043956043956, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40321; Mature: 40321

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCC
>Mature Secondary Structure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HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]