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The map label for this gene is TypA [H]

Identifier: 20807363

GI number: 20807363

Start: 893574

End: 895394

Strand: Direct

Name: TypA [H]

Synonym: TTE0882

Alternate gene names: 20807363

Gene position: 893574-895394 (Clockwise)

Preceding gene: 20807362

Following gene: 20807365

Centisome position: 33.23

GC content: 40.75

Gene sequence:

>1821_bases
ATGAGGGCAGTAAGGGAAGATGTAAGAAATGTAGCGATTATAGCTCATGTAGACCACGGCAAGACTACTTTGGTGGATGC
CATGTTAAAACAGAGCGGTATATTCAGGTGGAATGAGAAAGTGGAAGAGAGAATACTTGACTTTAATGACCTTGAAAGAG
AAAGAGGAATAACAATATTAGCTAAGAATACGGCGGTAAGGTATAAAAATGTGAAAATAAATATAGTTGATACGCCAGGA
CATGCTGATTTTAGCGGTGAAGTTGAAAGAGTCTTGAAGATGGTAGATGGAGTGCTTCTTCTGGTAGACTCTTTTGAAGG
ACCTATGCCCCAGACGAGATTTGTTTTGAGCAAGGCTTTGGAGCTTGATTTAAAGCCAATAGTTGTAATAAGTAAAATTG
ATAGGCCTGATGCAAGGCCAAATGAGGTCATTGACGAGGTTTTTGACCTCTTTATAGAGCTTGGCGCCAATGATGACCAG
ATTGATTTTCCTGTTGTGTATACTTCTGGAAAAGGTGGCATAGCAAAATTAGATTTAAAGGAGGAATCTCGTGATTTAAG
GCCTCTATTTGAAACTATAATAAAATACATTCCTGCTCCTTCAGGAGACATAGAGGGACCTTTTCAGCTTATAGTCACTA
CTTTGGACTATGACGACTACATCGGCAGGATTGCTATTGGAAAGGTAGTGAGAGGCAGAATTAAAGCTGGAGAAGAAGTG
GCGATATGCAAAAAGGGTGGAAGTATTCAGAAGTTCAACATAAACAACATATACCAATTTGAGGGATTAAGAAGGGTGCC
TGTGGAAGAGGCAAAACTTGGGGATATAGTAGCCGTTTCGGGAATTAGAGATATTGAGATAGGAGAGACAATAGCGGATA
AGGACAACCCTGAACCTGTAGACTTTGTAGAAATTGAGGAGCCTACTGTGTCCATGACTTTTAGTGTGAATACCAGTCCC
TTTGCAGGAACAGAAGGGAAATACGTGACTTCTAGACATCTAAGAGAAAGACTTTTTAAGGAACTGGAGACAAATGTGGC
TTTAAGAGTGGAGGAGACAGATTCCCCTGATTCTTTTAAGGTTTCTGGCAGAGGAGAATTGCACCTTTCTATTTTGATTG
AGACTATGAGAAGGGAAGGATATGAGCTACAGGTTTCAAAACCTACAGTTATATTCAAGGAAGTAAATGGAGTAAAGATG
GAACCTATTGAGCTTTTGACCGTAGATATTCCAGAAGAGTACATGGGAGTTGTAATGGAAAAATTGGGGCCCAGGAAAGC
CGAATTGATGGACATGCACACTTTAAAACCGGGGACTATAAGGCTTAAGTTTAAGATTCCTACAAGGGGTTTGATAGGAT
ACAGGTCAGAGTTTTTGACTGATACAAAGGGAAATGGAATAATGACCTCTGTGTTTTACGGCTATGAACCTTACAAAGGT
GAAATTCCCTCTCGATCAAGGGGAGCTCTTGTTGCTTTTGAGACGGGTATTGCCACGACTTACGGCCTTTATCACGCTCA
GGAAAGGGGAACTCTTTTTATTGAGCCAGGCACCAAGGTGTACGAAGGAATGGTTGTCGGCATGAATTCCCGAAGTGGGG
ATATTGAAGTCAATGTATGTAAGAAAAAACACGTCACCAATTTGCGGTCTGCAACGGCTGAAGAAGCCCTAAGGCTTTCT
CCTGTGAAAAAGATGACTTTAGAGGAAGCTCTAGAATTTATAGATAATGACGAGTTGGTAGAAGTTACGCCTCAGAGCAT
AAGAATAAGAAAGAAAATTTTGGATTCCCAGCAGAGGTACAAAAGTGCAAAACAAAAATAG

Upstream 100 bases:

>100_bases
TGACACTATCAAAGTGCTCTTTTTATATTGACTATTTTGATGGCTTGGTATATCATATAATACTGTACATGATATACCTT
TTTATGGAAGGAGATACCTT

Downstream 100 bases:

>100_bases
AAATGGAGCCTTTTGGCTCCCTTTTATTTATACAAGTCATTTAAAATTTTGTTTATGTAATTTATAGTTTCAGGGTAAGG
GGGAATGCCTTGGTATTTTT

Product: stress response membrane GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MRAVREDVRNVAIIAHVDHGKTTLVDAMLKQSGIFRWNEKVEERILDFNDLERERGITILAKNTAVRYKNVKINIVDTPG
HADFSGEVERVLKMVDGVLLLVDSFEGPMPQTRFVLSKALELDLKPIVVISKIDRPDARPNEVIDEVFDLFIELGANDDQ
IDFPVVYTSGKGGIAKLDLKEESRDLRPLFETIIKYIPAPSGDIEGPFQLIVTTLDYDDYIGRIAIGKVVRGRIKAGEEV
AICKKGGSIQKFNINNIYQFEGLRRVPVEEAKLGDIVAVSGIRDIEIGETIADKDNPEPVDFVEIEEPTVSMTFSVNTSP
FAGTEGKYVTSRHLRERLFKELETNVALRVEETDSPDSFKVSGRGELHLSILIETMRREGYELQVSKPTVIFKEVNGVKM
EPIELLTVDIPEEYMGVVMEKLGPRKAELMDMHTLKPGTIRLKFKIPTRGLIGYRSEFLTDTKGNGIMTSVFYGYEPYKG
EIPSRSRGALVAFETGIATTYGLYHAQERGTLFIEPGTKVYEGMVVGMNSRSGDIEVNVCKKKHVTNLRSATAEEALRLS
PVKKMTLEEALEFIDNDELVEVTPQSIRIRKKILDSQQRYKSAKQK

Sequences:

>Translated_606_residues
MRAVREDVRNVAIIAHVDHGKTTLVDAMLKQSGIFRWNEKVEERILDFNDLERERGITILAKNTAVRYKNVKINIVDTPG
HADFSGEVERVLKMVDGVLLLVDSFEGPMPQTRFVLSKALELDLKPIVVISKIDRPDARPNEVIDEVFDLFIELGANDDQ
IDFPVVYTSGKGGIAKLDLKEESRDLRPLFETIIKYIPAPSGDIEGPFQLIVTTLDYDDYIGRIAIGKVVRGRIKAGEEV
AICKKGGSIQKFNINNIYQFEGLRRVPVEEAKLGDIVAVSGIRDIEIGETIADKDNPEPVDFVEIEEPTVSMTFSVNTSP
FAGTEGKYVTSRHLRERLFKELETNVALRVEETDSPDSFKVSGRGELHLSILIETMRREGYELQVSKPTVIFKEVNGVKM
EPIELLTVDIPEEYMGVVMEKLGPRKAELMDMHTLKPGTIRLKFKIPTRGLIGYRSEFLTDTKGNGIMTSVFYGYEPYKG
EIPSRSRGALVAFETGIATTYGLYHAQERGTLFIEPGTKVYEGMVVGMNSRSGDIEVNVCKKKHVTNLRSATAEEALRLS
PVKKMTLEEALEFIDNDELVEVTPQSIRIRKKILDSQQRYKSAKQK
>Mature_606_residues
MRAVREDVRNVAIIAHVDHGKTTLVDAMLKQSGIFRWNEKVEERILDFNDLERERGITILAKNTAVRYKNVKINIVDTPG
HADFSGEVERVLKMVDGVLLLVDSFEGPMPQTRFVLSKALELDLKPIVVISKIDRPDARPNEVIDEVFDLFIELGANDDQ
IDFPVVYTSGKGGIAKLDLKEESRDLRPLFETIIKYIPAPSGDIEGPFQLIVTTLDYDDYIGRIAIGKVVRGRIKAGEEV
AICKKGGSIQKFNINNIYQFEGLRRVPVEEAKLGDIVAVSGIRDIEIGETIADKDNPEPVDFVEIEEPTVSMTFSVNTSP
FAGTEGKYVTSRHLRERLFKELETNVALRVEETDSPDSFKVSGRGELHLSILIETMRREGYELQVSKPTVIFKEVNGVKM
EPIELLTVDIPEEYMGVVMEKLGPRKAELMDMHTLKPGTIRLKFKIPTRGLIGYRSEFLTDTKGNGIMTSVFYGYEPYKG
EIPSRSRGALVAFETGIATTYGLYHAQERGTLFIEPGTKVYEGMVVGMNSRSGDIEVNVCKKKHVTNLRSATAEEALRLS
PVKKMTLEEALEFIDNDELVEVTPQSIRIRKKILDSQQRYKSAKQK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=493, Percent_Identity=27.3833671399594, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=39.8496240601504, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI18390331, Length=201, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4503483, Length=147, Percent_Identity=36.0544217687075, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI34147630, Length=272, Percent_Identity=31.25, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI25306287, Length=133, Percent_Identity=37.593984962406, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI19923640, Length=133, Percent_Identity=37.593984962406, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI25306283, Length=133, Percent_Identity=37.593984962406, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI217272894, Length=141, Percent_Identity=36.1702127659575, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI217272892, Length=141, Percent_Identity=36.1702127659575, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=31.0077519379845, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI48994988, Length=600, Percent_Identity=53, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=476, Percent_Identity=29.2016806722689, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789738, Length=161, Percent_Identity=35.4037267080745, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790835, Length=377, Percent_Identity=23.6074270557029, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789737, Length=324, Percent_Identity=29.320987654321, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790412, Length=324, Percent_Identity=29.320987654321, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557151, Length=330, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17533571, Length=177, Percent_Identity=36.7231638418079, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=37.3239436619718, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=177, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=37.6923076923077, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=37.6923076923077, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=189, Percent_Identity=31.7460317460317, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556456, Length=282, Percent_Identity=29.0780141843972, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323320, Length=487, Percent_Identity=29.1581108829569, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324707, Length=147, Percent_Identity=43.5374149659864, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=147, Percent_Identity=43.5374149659864, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324761, Length=279, Percent_Identity=29.7491039426523, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6322359, Length=155, Percent_Identity=38.0645161290323, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=35.5704697986577, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=312, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI78706572, Length=520, Percent_Identity=25.5769230769231, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=41.4285714285714, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24585711, Length=153, Percent_Identity=38.562091503268, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24585713, Length=153, Percent_Identity=38.562091503268, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24585709, Length=153, Percent_Identity=38.562091503268, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI281363316, Length=321, Percent_Identity=28.3489096573209, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17864358, Length=321, Percent_Identity=28.3489096573209, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24582462, Length=179, Percent_Identity=35.7541899441341, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357743, Length=173, Percent_Identity=36.9942196531792, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221458488, Length=150, Percent_Identity=38, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19921738, Length=232, Percent_Identity=31.4655172413793, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28572034, Length=281, Percent_Identity=27.7580071174377, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68119; Mature: 68119

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVREDVRNVAIIAHVDHGKTTLVDAMLKQSGIFRWNEKVEERILDFNDLERERGITIL
CCHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHCCEEEE
AKNTAVRYKNVKINIVDTPGHADFSGEVERVLKMVDGVLLLVDSFEGPMPQTRFVLSKAL
EECCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
ELDLKPIVVISKIDRPDARPNEVIDEVFDLFIELGANDDQIDFPVVYTSGKGGIAKLDLK
HCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEECC
EESRDLRPLFETIIKYIPAPSGDIEGPFQLIVTTLDYDDYIGRIAIGKVVRGRIKAGEEV
HHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
AICKKGGSIQKFNINNIYQFEGLRRVPVEEAKLGDIVAVSGIRDIEIGETIADKDNPEPV
EEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCEEEECCCCEEECCCHHCCCCCCCCC
DFVEIEEPTVSMTFSVNTSPFAGTEGKYVTSRHLRERLFKELETNVALRVEETDSPDSFK
CEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
VSGRGELHLSILIETMRREGYELQVSKPTVIFKEVNGVKMEPIELLTVDIPEEYMGVVME
ECCCCCEEHHHHHHHHHCCCCEEEECCCEEEEEECCCCEECCEEEEEEECCHHHHHHHHH
KLGPRKAELMDMHTLKPGTIRLKFKIPTRGLIGYRSEFLTDTKGNGIMTSVFYGYEPYKG
HCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCC
EIPSRSRGALVAFETGIATTYGLYHAQERGTLFIEPGTKVYEGMVVGMNSRSGDIEVNVC
CCCCCCCCEEEEEECCCCCHHHEEEECCCCEEEECCCCCEECCEEEEECCCCCCEEEEEE
KKKHVTNLRSATAEEALRLSPVKKMTLEEALEFIDNDELVEVTPQSIRIRKKILDSQQRY
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
KSAKQK
HHHCCC
>Mature Secondary Structure
MRAVREDVRNVAIIAHVDHGKTTLVDAMLKQSGIFRWNEKVEERILDFNDLERERGITIL
CCHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHCCEEEE
AKNTAVRYKNVKINIVDTPGHADFSGEVERVLKMVDGVLLLVDSFEGPMPQTRFVLSKAL
EECCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
ELDLKPIVVISKIDRPDARPNEVIDEVFDLFIELGANDDQIDFPVVYTSGKGGIAKLDLK
HCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEECC
EESRDLRPLFETIIKYIPAPSGDIEGPFQLIVTTLDYDDYIGRIAIGKVVRGRIKAGEEV
HHCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
AICKKGGSIQKFNINNIYQFEGLRRVPVEEAKLGDIVAVSGIRDIEIGETIADKDNPEPV
EEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCEEEECCCCEEECCCHHCCCCCCCCC
DFVEIEEPTVSMTFSVNTSPFAGTEGKYVTSRHLRERLFKELETNVALRVEETDSPDSFK
CEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
VSGRGELHLSILIETMRREGYELQVSKPTVIFKEVNGVKMEPIELLTVDIPEEYMGVVME
ECCCCCEEHHHHHHHHHCCCCEEEECCCEEEEEECCCCEECCEEEEEEECCHHHHHHHHH
KLGPRKAELMDMHTLKPGTIRLKFKIPTRGLIGYRSEFLTDTKGNGIMTSVFYGYEPYKG
HCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCC
EIPSRSRGALVAFETGIATTYGLYHAQERGTLFIEPGTKVYEGMVVGMNSRSGDIEVNVC
CCCCCCCCEEEEEECCCCCHHHEEEECCCCEEEECCCCCEECCEEEEECCCCCCEEEEEE
KKKHVTNLRSATAEEALRLSPVKKMTLEEALEFIDNDELVEVTPQSIRIRKKILDSQQRY
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
KSAKQK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]