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The map label for this gene is PurR6 [H]

Identifier: 20807279

GI number: 20807279

Start: 793608

End: 794618

Strand: Direct

Name: PurR6 [H]

Synonym: TTE0797

Alternate gene names: 20807279

Gene position: 793608-794618 (Clockwise)

Preceding gene: 20807278

Following gene: 20807280

Centisome position: 29.51

GC content: 37.09

Gene sequence:

>1011_bases
ATGGCGGTTACAATAAAAGACATAGCAAAATATGCAGGGGTTTCTGTAACCACTGTTTCTCGCGCATTGAACGGGTACCC
GGATGTAAGCGAAGAAACTAGAGCAAAAATAAAAAAAATTGCTGAAGAATTAAATTATACTCCTAATTCTATTGCAAGAG
GGCTTGTAACTAACAAGACCCAAACAATAGGTATGGTTGTATCAGAACTCATAAAACCGGGAGTATATCATCCATTTTTT
CTTGAAGTACTTGCAGGAATAAAAGCAGGGCTAAAAAAGGACAGATATGACCTTATACTTTTTACTGTGGACCCAGAGAG
TCAAGATGCCACTTCTTATGAAAAACTTTGCAATGACAGGAAAGTGGAAGGGGCAATTGTAGAAGGGTTGAGATTAAGCG
ACCCTTACATTGAAGAGATAAAGGGGACACAAATTCCTACAGTTTTAATTGACATACCGATTTTGACAGATAAAGTTGGA
TATGTAAGTTCAGATAATGTTCAGGCGGCTTTTGAAGCCACTAGTTATCTTATTAAATTAGGACACAAAAACATAGGATT
TATAAACGGTCATAAAGATGCGGCTGTTAGCTTTGAAAGATTGGAAGGATATAAAAAAGCTCTTGAAAAAAATGATATCC
CTTACAGAGAAGAGTATGTGATTTTTGCTGATTTCACACAAGAAGGCGGTTATAATGCTTTTAAAACTCTGATTTTTGAA
CATCCTGAAATAACTGCAATTTTTCACGCTTCTGATTTAATGGCAATGGGGTCCTACAGGGCGGCAAAGGATTTGGGAAT
GAGGATACCGGAGGATATCTCTTTGGTAGGATTTGATGATATAGAACTTGCATCACTTATCACGCCGGCATTGACGACTA
TAAGGCAGGATACTTTTAAGATGGGATATACTGCTGCAAAACATTTGCTTGCAATTATAAGAGGAGAAAAGCCTCAACAT
ATAGTTATTCCCCATAAACTTGTAGTTAGAGATTCTGCAAGGAAATTGTGA

Upstream 100 bases:

>100_bases
TGTGTCCTTATGGAAAGAGGAAAAAATCTGTTGACAGGTGAAAAGGTTTTTGATACAATGAAAATGAAGTAACCAAAACG
TTTTGGGAAAGGTGAAGGAG

Downstream 100 bases:

>100_bases
TATTTTTTTAAAAGTCATCCAAAACGTTTCGGATAAAATCTTTGCCAGAGGTCAGGAGGTATGCAAGTGATAAAAAAAGT
AGAAGAATTGATGGGTGATG

Product: transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKTQTIGMVVSELIKPGVYHPFF
LEVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVG
YVSSDNVQAAFEATSYLIKLGHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFADFTQEGGYNAFKTLIFE
HPEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTFKMGYTAAKHLLAIIRGEKPQH
IVIPHKLVVRDSARKL

Sequences:

>Translated_336_residues
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKTQTIGMVVSELIKPGVYHPFF
LEVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVG
YVSSDNVQAAFEATSYLIKLGHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFADFTQEGGYNAFKTLIFE
HPEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTFKMGYTAAKHLLAIIRGEKPQH
IVIPHKLVVRDSARKL
>Mature_335_residues
AVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKTQTIGMVVSELIKPGVYHPFFL
EVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDRKVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVGY
VSSDNVQAAFEATSYLIKLGHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFADFTQEGGYNAFKTLIFEH
PEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTFKMGYTAAKHLLAIIRGEKPQHI
VIPHKLVVRDSARKL

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=341, Percent_Identity=34.3108504398827, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=33.7313432835821, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1790194, Length=303, Percent_Identity=32.6732673267327, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=31.0240963855422, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=30.7432432432432, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=31.1864406779661, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=31.0650887573964, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788474, Length=342, Percent_Identity=31.2865497076023, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787906, Length=339, Percent_Identity=27.1386430678466, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=26.5861027190332, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=27.3584905660377, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789456, Length=355, Percent_Identity=27.6056338028169, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786268, Length=307, Percent_Identity=25.0814332247557, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790689, Length=335, Percent_Identity=24.1791044776119, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790192, Length=286, Percent_Identity=27.6223776223776, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37315; Mature: 37184

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKT
CEEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCH
QTIGMVVSELIKPGVYHPFFLEVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCC
KVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVGYVSSDNVQAAFEATSYLIKL
CCCHHHHCCCCCCCCHHHHHCCCCCCEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
GHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFADFTQEGGYNAFKTLIFE
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCC
HPEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTFK
CCCEEEEEEHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
MGYTAAKHLLAIIRGEKPQHIVIPHKLVVRDSARKL
HHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCC
>Mature Secondary Structure 
AVTIKDIAKYAGVSVTTVSRALNGYPDVSEETRAKIKKIAEELNYTPNSIARGLVTNKT
EEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCH
QTIGMVVSELIKPGVYHPFFLEVLAGIKAGLKKDRYDLILFTVDPESQDATSYEKLCNDR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCC
KVEGAIVEGLRLSDPYIEEIKGTQIPTVLIDIPILTDKVGYVSSDNVQAAFEATSYLIKL
CCCHHHHCCCCCCCCHHHHHCCCCCCEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
GHKNIGFINGHKDAAVSFERLEGYKKALEKNDIPYREEYVIFADFTQEGGYNAFKTLIFE
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCC
HPEITAIFHASDLMAMGSYRAAKDLGMRIPEDISLVGFDDIELASLITPALTTIRQDTFK
CCCEEEEEEHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
MGYTAAKHLLAIIRGEKPQHIVIPHKLVVRDSARKL
HHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]