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The map label for this gene is OmpR2 [H]

Identifier: 20807256

GI number: 20807256

Start: 773554

End: 774228

Strand: Reverse

Name: OmpR2 [H]

Synonym: TTE0774

Alternate gene names: 20807256

Gene position: 774228-773554 (Counterclockwise)

Preceding gene: 20807259

Following gene: 20807255

Centisome position: 28.79

GC content: 36.89

Gene sequence:

>675_bases
TTGATGCACAAAGTTCTGGTAATTGAAGATGAAGAAGGAATGAGAGATATATTGAAAACTTATTTAGAAAATAATGGATA
TCAAGTATTAACAGCAGAAAATGGAAAAGAAGGCCTTGACCTCTTCAACGAAAACAAAGATATAAAGATAATCCTCTTGG
ATATAATGCTCCCTGATATAAGCGGATGGAGCCTTTTAAAAACAATAAGGGAAACATCAAAAGTTCCTGTGATGATGATA
ACAGCAAGAGGAGAAGAATACGACAAACTTTTAGGCTTTGAATTGGGGGCAGATGATTATGTAGTAAAGCCCTTTAGTCC
CAGAGAAGTAGTGGCCCGTGTAAAAGCAATTTTATCAAGGACATATGGCTCTCAAGATGATGGAAAAACAGAATATCAAG
GGATTGTCATGGATGTTCATTCGAGGGAAGTCACTGTTGATGGCAAAAAAATTGAGCTCACTCCAAAAGAATTTGACCTT
TTAAAGCTTTTACTGGATAACAAGGGAAAAGTTGTATCCCGCGAAAAATGTCTCAATGAAGTCTGGGGCTACGATTTTTA
CGGAGATTTGAGGACAGTCGACACTCACATAAAACAGCTGAGAGAAAAATTGGGTGAGAAAAGAAATCTTATAAAAACTG
TGTGGGGAATAGGTTATAAACTGGAAGGTGACTGA

Upstream 100 bases:

>100_bases
TGACACATTTTTTTAAAATCTGTGAGGAAAGTGTGAAAGTTTAATTTAAAATATTGTAAACTTGCCGAAAAAAAAGTAAA
CTAAAGTTGGGAGGTGTTTT

Downstream 100 bases:

>100_bases
TTTGAAGGGAATAAGGAAAAAACTTTTTATATCATACCTTTCCATAGGAATGGTAGTACTTTTGCTTTTCTGGCTGACAC
AGGTAGTCTTCATAAACAGA

Product: response regulator

Products: NA

Alternate protein names: Staphylococcal respiratory response protein A [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MMHKVLVIEDEEGMRDILKTYLENNGYQVLTAENGKEGLDLFNENKDIKIILLDIMLPDISGWSLLKTIRETSKVPVMMI
TARGEEYDKLLGFELGADDYVVKPFSPREVVARVKAILSRTYGSQDDGKTEYQGIVMDVHSREVTVDGKKIELTPKEFDL
LKLLLDNKGKVVSREKCLNEVWGYDFYGDLRTVDTHIKQLREKLGEKRNLIKTVWGIGYKLEGD

Sequences:

>Translated_224_residues
MMHKVLVIEDEEGMRDILKTYLENNGYQVLTAENGKEGLDLFNENKDIKIILLDIMLPDISGWSLLKTIRETSKVPVMMI
TARGEEYDKLLGFELGADDYVVKPFSPREVVARVKAILSRTYGSQDDGKTEYQGIVMDVHSREVTVDGKKIELTPKEFDL
LKLLLDNKGKVVSREKCLNEVWGYDFYGDLRTVDTHIKQLREKLGEKRNLIKTVWGIGYKLEGD
>Mature_224_residues
MMHKVLVIEDEEGMRDILKTYLENNGYQVLTAENGKEGLDLFNENKDIKIILLDIMLPDISGWSLLKTIRETSKVPVMMI
TARGEEYDKLLGFELGADDYVVKPFSPREVVARVKAILSRTYGSQDDGKTEYQGIVMDVHSREVTVDGKKIELTPKEFDL
LKLLLDNKGKVVSREKCLNEVWGYDFYGDLRTVDTHIKQLREKLGEKRNLIKTVWGIGYKLEGD

Specific function: Member of the two-component regulatory system srrA/srrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels. SrrA binds to the agr, spa and tst promoters and represses their transcript

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=41.1504424778761, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.7079646017699, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=40.3508771929825, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=38.2882882882883, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.920704845815, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=38.1818181818182, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=40.5286343612335, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=35.9307359307359, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.9307359307359, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=36.3636363636364, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=34.6846846846847, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=35.1111111111111, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=30.8823529411765, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25675; Mature: 25675

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHKVLVIEDEEGMRDILKTYLENNGYQVLTAENGKEGLDLFNENKDIKIILLDIMLPDI
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCEEEEEEEEECCCC
SGWSLLKTIRETSKVPVMMITARGEEYDKLLGFELGADDYVVKPFSPREVVARVKAILSR
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHHH
TYGSQDDGKTEYQGIVMDVHSREVTVDGKKIELTPKEFDLLKLLLDNKGKVVSREKCLNE
HCCCCCCCCCHHCEEEEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEHHHHHHHH
VWGYDFYGDLRTVDTHIKQLREKLGEKRNLIKTVWGIGYKLEGD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MMHKVLVIEDEEGMRDILKTYLENNGYQVLTAENGKEGLDLFNENKDIKIILLDIMLPDI
CCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCEEEEEEEEECCCC
SGWSLLKTIRETSKVPVMMITARGEEYDKLLGFELGADDYVVKPFSPREVVARVKAILSR
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHHH
TYGSQDDGKTEYQGIVMDVHSREVTVDGKKIELTPKEFDLLKLLLDNKGKVVSREKCLNE
HCCCCCCCCCHHCEEEEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEHHHHHHHH
VWGYDFYGDLRTVDTHIKQLREKLGEKRNLIKTVWGIGYKLEGD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA