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The map label for this gene is GalU [H]

Identifier: 20807219

GI number: 20807219

Start: 735617

End: 736525

Strand: Direct

Name: GalU [H]

Synonym: TTE0732

Alternate gene names: 20807219

Gene position: 735617-736525 (Clockwise)

Preceding gene: 20807218

Following gene: 20807220

Centisome position: 27.35

GC content: 38.06

Gene sequence:

>909_bases
ATGAAAATAAAGAAAGCGATAATTCCAGCAGCGGGCCTTGGTACCAGGTTTTTACCTGCTACCAAGGCTCAGCCTAAGGA
AATGCTTCCAATTGTAGACAAGCCTACTATACAGTACATAGTGGAAGAAGCGGTACAGTCAGGAATAGAGGATATTCTTA
TAATAACTGGAAGGAACAAAAGAGCCATAGAAGATCATTTTGACAAATCTGTAGAATTGGAGCTAGAATTAAAGAAAAAG
AATCAGGAAAGTTTACTAAGCCTTGTAGAAGATATTAGCAATATGGTAAATATTCACTATATAAGACAAAAAGAACCTAA
AGGCTTGGGGCATGCCATTTACTGTGCTAAATCTTTTGTTGGCAATGAGCCTTTCGCAGTGCTTTTAGGAGATGACGTGG
TGGATGCTGAAGTACCTGTTTTAAAGCAGATGATAGAGCAGTTTGAGAGGTATAATTGCACCATAATTGGAGTGCAGGAA
GTGCCTGAAGAGGATGTACATAAATATGGAATTGTAAGCGGTACTTTTATTGAGGATAGGCTATATAAAGTCAATGATTT
GATAGAAAAGCCAAGGAGAGAGGAAGCACCTTCTAATATAGCTATTTTGGGAAGGTATATAATTACACCGCGAATATTTG
AGATTTTGGAACATACGCCTCCTGGAAGAGGAGGAGAAATACAATTGACAGACGCTTTAAAAACTCTTTTAAATTATGAG
GCCATTTACGCCTATAATTTTATAGGCAAAAGGTATGATGTGGGGGATAAACTGGGCTATCTCATGGCGACTGTGGAATA
TGCTTTGAAAAGGGAAGATTTGAGAGAGCCTTTTAAAAGGTATTTGATAACAATTGTCCAGGATTTACTTGGTATGGAAG
AAGCCGCAGTGACTGAAAGAGATGTGTAA

Upstream 100 bases:

>100_bases
AGCTAGAACTTCAGAAAAGCTTGAGGAAATTAAAAAAGAACTTTCAGAGGCTTTAGCCAAGTTTGGCGTGAAGTTTGAAT
AACGGAAGAGGGGAAAGTTA

Downstream 100 bases:

>100_bases
TAATGTAGAGTAGGGTGGAGAGGGGAATAAGGGTATGATGGAAGAGGAACTTGACCTCAGAGAAGTTTTTTTGATTCTTA
GAAAAAGAATAAAGATTATA

Product: UDP-glucose pyrophosphorylase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVQSGIEDILIITGRNKRAIEDHFDKSVELELELKKK
NQESLLSLVEDISNMVNIHYIRQKEPKGLGHAIYCAKSFVGNEPFAVLLGDDVVDAEVPVLKQMIEQFERYNCTIIGVQE
VPEEDVHKYGIVSGTFIEDRLYKVNDLIEKPRREEAPSNIAILGRYIITPRIFEILEHTPPGRGGEIQLTDALKTLLNYE
AIYAYNFIGKRYDVGDKLGYLMATVEYALKREDLREPFKRYLITIVQDLLGMEEAAVTERDV

Sequences:

>Translated_302_residues
MKIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVQSGIEDILIITGRNKRAIEDHFDKSVELELELKKK
NQESLLSLVEDISNMVNIHYIRQKEPKGLGHAIYCAKSFVGNEPFAVLLGDDVVDAEVPVLKQMIEQFERYNCTIIGVQE
VPEEDVHKYGIVSGTFIEDRLYKVNDLIEKPRREEAPSNIAILGRYIITPRIFEILEHTPPGRGGEIQLTDALKTLLNYE
AIYAYNFIGKRYDVGDKLGYLMATVEYALKREDLREPFKRYLITIVQDLLGMEEAAVTERDV
>Mature_302_residues
MKIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVQSGIEDILIITGRNKRAIEDHFDKSVELELELKKK
NQESLLSLVEDISNMVNIHYIRQKEPKGLGHAIYCAKSFVGNEPFAVLLGDDVVDAEVPVLKQMIEQFERYNCTIIGVQE
VPEEDVHKYGIVSGTFIEDRLYKVNDLIEKPRREEAPSNIAILGRYIITPRIFEILEHTPPGRGGEIQLTDALKTLLNYE
AIYAYNFIGKRYDVGDKLGYLMATVEYALKREDLREPFKRYLITIVQDLLGMEEAAVTERDV

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=290, Percent_Identity=46.2068965517241, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1788355, Length=276, Percent_Identity=43.4782608695652, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=28.6324786324786, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788351, Length=237, Percent_Identity=29.957805907173, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 34321; Mature: 34321

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVQSGIEDILIITGRNK
CCCCHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
RAIEDHFDKSVELELELKKKNQESLLSLVEDISNMVNIHYIRQKEPKGLGHAIYCAKSFV
CHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHC
GNEPFAVLLGDDVVDAEVPVLKQMIEQFERYNCTIIGVQEVPEEDVHKYGIVSGTFIEDR
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHCCCCCCHHHHH
LYKVNDLIEKPRREEAPSNIAILGRYIITPRIFEILEHTPPGRGGEIQLTDALKTLLNYE
HHHHHHHHHCCHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCHH
AIYAYNFIGKRYDVGDKLGYLMATVEYALKREDLREPFKRYLITIVQDLLGMEEAAVTER
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
DV
CC
>Mature Secondary Structure
MKIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVQSGIEDILIITGRNK
CCCCHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
RAIEDHFDKSVELELELKKKNQESLLSLVEDISNMVNIHYIRQKEPKGLGHAIYCAKSFV
CHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHC
GNEPFAVLLGDDVVDAEVPVLKQMIEQFERYNCTIIGVQEVPEEDVHKYGIVSGTFIEDR
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHCCCCCCHHHHH
LYKVNDLIEKPRREEAPSNIAILGRYIITPRIFEILEHTPPGRGGEIQLTDALKTLLNYE
HHHHHHHHHCCHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCHH
AIYAYNFIGKRYDVGDKLGYLMATVEYALKREDLREPFKRYLITIVQDLLGMEEAAVTER
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
DV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]