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The map label for this gene is AtpD

Identifier: 20807130

GI number: 20807130

Start: 640311

End: 641696

Strand: Direct

Name: AtpD

Synonym: TTE0637

Alternate gene names: 20807130

Gene position: 640311-641696 (Clockwise)

Preceding gene: 20807129

Following gene: 20807131

Centisome position: 23.81

GC content: 45.74

Gene sequence:

>1386_bases
TTGAAAAAAGGTTACATTACACAGGTAATTGGTCCTGTTGTAGATATAAGGTTTGAAGGGGATCTTCCTCCAATAAATAA
CGCCATAAAAATACCTATGGGAGATAGAGAGCTTGTGGTGGAAGTAGCCCAGCACATAGGGGATAACACAGTAAGATGTG
TGGCAATGGCATCTACAGACGGACTGAGAAGAGGAATGGAGTGCATAGACACCGGCGGACCTATAATGGTTCCTGTTGGA
AAAGGCGTGCTGGGCAGGATGTTTAACGTCTTAGGACAGCCCATTGACGAGCTGGGAGAAGTAAAGGACGTAAAATACAT
GCCCATTCACAAAAAGCCACCTTCTTTTGAGGAGCAAAACCCTGCAACGGAGATTTTAGAGACAGGAATAAAAGTAATTG
ACCTTCTCACACCCTATCCAAAAGGTGGAAAGATAGGGCTTTTTGGCGGTGCAGGTGTTGGGAAGACAGTCCTTATAATG
GAGCTTATACGAAATGTGGCCATTGAGCACGGCGGTTACTCCATATTTGCAGGAGTAGGTGAAAGGTCCCGTGAAGGGAA
TGAATTGTGGCTTGAAATGCACGAGGCTGGAGTTATAGACAAGACAGCTTTTGTGTTCGGTCAGATGAATGAGCCTCCTG
GAGCCAGAATGAGAGTGGGACTTGCAGGGCTTACCATAGCAGAGTACTTTAGGGACGAAGAGCATCAGGACGTTTTGCTT
TTCATAGACAACATCTTTAGGTTTGTACAGGCAGGGTCAGAGGTTTCTGCTCTTTTAGGCAGAATGCCTTCTGCTGTTGG
ATACCAGCCCACTCTTGCTACTGAAATGGGCGCTCTTCAGGAGAGAATCACATCTACAAAGAAGGGTTCTATAACATCGG
TTCAGGCTATTTACGTTCCTGCGGACGACTTGACAGACCCTGCTCCAGCGACAACTTTTGCTCACTTGGATGCTACTACA
GTTTTGTCAAGGAGCATTGCAGAAATGGGTATTTACCCTGCAGTTGACCCGTTGGATTCTACCTCCAGAATACTTGAACC
CCACATAGTAGGAGAAGAGCACTATTACGTTGCTAGGAAAGTGCAGGAAATTCTGCAAAGGTATAAAGAATTGCAGGATA
TCATAGCCATACTCGGCATGGAAGAGCTGACGGAGGAAGACAGGCTCATTGTGTACAGGGCAAGAAAGATACAAAGATTC
TTGTCACAGCCTTTCTTCGTAGCAGAGGCCTTCACTGGGACTCCGGGTAAATATGTTCCTCTCAAAGAGACCATAAGGGG
ATTCAAGAAGATTGTGGAGGGAGAAATGGACGACATACCAGAGCCAGCCTTTTACATGGTAGGAACGATCGATGAAGTTT
ATGAGAAAGCAGAGAAGATGAAATGA

Upstream 100 bases:

>100_bases
AAAGCTCACTCTTTTGTACAACAAGCTAAGGCAGGCTTCTATAACGCAGGAAATTATAGAAATAATTACAGGGGCATCTG
TATAAAAAGGAGATGATAGT

Downstream 100 bases:

>100_bases
GGTGAAATAAATGGATAAAACCTTTCACCTCGAAGTATTGACCCCTTACAGAAAGTTTTATGAAGGGGATGTGGAAGAGA
TAATTGTGACTACTACCACA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKKGYITQVIGPVVDIRFEGDLPPINNAIKIPMGDRELVVEVAQHIGDNTVRCVAMASTDGLRRGMECIDTGGPIMVPVG
KGVLGRMFNVLGQPIDELGEVKDVKYMPIHKKPPSFEEQNPATEILETGIKVIDLLTPYPKGGKIGLFGGAGVGKTVLIM
ELIRNVAIEHGGYSIFAGVGERSREGNELWLEMHEAGVIDKTAFVFGQMNEPPGARMRVGLAGLTIAEYFRDEEHQDVLL
FIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATT
VLSRSIAEMGIYPAVDPLDSTSRILEPHIVGEEHYYVARKVQEILQRYKELQDIIAILGMEELTEEDRLIVYRARKIQRF
LSQPFFVAEAFTGTPGKYVPLKETIRGFKKIVEGEMDDIPEPAFYMVGTIDEVYEKAEKMK

Sequences:

>Translated_461_residues
MKKGYITQVIGPVVDIRFEGDLPPINNAIKIPMGDRELVVEVAQHIGDNTVRCVAMASTDGLRRGMECIDTGGPIMVPVG
KGVLGRMFNVLGQPIDELGEVKDVKYMPIHKKPPSFEEQNPATEILETGIKVIDLLTPYPKGGKIGLFGGAGVGKTVLIM
ELIRNVAIEHGGYSIFAGVGERSREGNELWLEMHEAGVIDKTAFVFGQMNEPPGARMRVGLAGLTIAEYFRDEEHQDVLL
FIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATT
VLSRSIAEMGIYPAVDPLDSTSRILEPHIVGEEHYYVARKVQEILQRYKELQDIIAILGMEELTEEDRLIVYRARKIQRF
LSQPFFVAEAFTGTPGKYVPLKETIRGFKKIVEGEMDDIPEPAFYMVGTIDEVYEKAEKMK
>Mature_461_residues
MKKGYITQVIGPVVDIRFEGDLPPINNAIKIPMGDRELVVEVAQHIGDNTVRCVAMASTDGLRRGMECIDTGGPIMVPVG
KGVLGRMFNVLGQPIDELGEVKDVKYMPIHKKPPSFEEQNPATEILETGIKVIDLLTPYPKGGKIGLFGGAGVGKTVLIM
ELIRNVAIEHGGYSIFAGVGERSREGNELWLEMHEAGVIDKTAFVFGQMNEPPGARMRVGLAGLTIAEYFRDEEHQDVLL
FIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATT
VLSRSIAEMGIYPAVDPLDSTSRILEPHIVGEEHYYVARKVQEILQRYKELQDIIAILGMEELTEEDRLIVYRARKIQRF
LSQPFFVAEAFTGTPGKYVPLKETIRGFKKIVEGEMDDIPEPAFYMVGTIDEVYEKAEKMK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=463, Percent_Identity=70.8423326133909, Blast_Score=661, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=354, Percent_Identity=25.7062146892655, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI19913424, Length=326, Percent_Identity=28.5276073619632, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI19913426, Length=358, Percent_Identity=24.8603351955307, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI50345984, Length=285, Percent_Identity=25.2631578947368, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4757810, Length=285, Percent_Identity=25.2631578947368, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1790170, Length=461, Percent_Identity=68.1127982646421, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=28.8819875776398, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790172, Length=318, Percent_Identity=26.7295597484277, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=464, Percent_Identity=69.1810344827586, Blast_Score=654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=412, Percent_Identity=25, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=418, Percent_Identity=24.6411483253589, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17565854, Length=345, Percent_Identity=27.536231884058, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71988080, Length=314, Percent_Identity=25.1592356687898, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=314, Percent_Identity=25.1592356687898, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=305, Percent_Identity=23.9344262295082, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=456, Percent_Identity=70.6140350877193, Blast_Score=652, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=351, Percent_Identity=25.6410256410256, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319370, Length=349, Percent_Identity=25.214899713467, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320016, Length=251, Percent_Identity=25.0996015936255, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638766, Length=464, Percent_Identity=70.4741379310345, Blast_Score=655, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=468, Percent_Identity=67.948717948718, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI20129479, Length=358, Percent_Identity=26.536312849162, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24583988, Length=348, Percent_Identity=26.1494252873563, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24583986, Length=348, Percent_Identity=26.1494252873563, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24583984, Length=348, Percent_Identity=26.1494252873563, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=27.9503105590062, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281361666, Length=355, Percent_Identity=25.6338028169014, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=355, Percent_Identity=25.6338028169014, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=355, Percent_Identity=25.6338028169014, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=52.7472527472528, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24658560, Length=285, Percent_Identity=24.5614035087719, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_THETN (Q8RC15)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622301.1
- HSSP:   P00829
- ProteinModelPortal:   Q8RC15
- SMR:   Q8RC15
- GeneID:   996574
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0637
- NMPDR:   fig|273068.3.peg.312
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   TTEN273068:TTE0637-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50861; Mature: 50861

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGYITQVIGPVVDIRFEGDLPPINNAIKIPMGDRELVVEVAQHIGDNTVRCVAMASTD
CCCCHHHHHHCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCH
GLRRGMECIDTGGPIMVPVGKGVLGRMFNVLGQPIDELGEVKDVKYMPIHKKPPSFEEQN
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCCCCC
PATEILETGIKVIDLLTPYPKGGKIGLFGGAGVGKTVLIMELIRNVAIEHGGYSIFAGVG
CHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
ERSREGNELWLEMHEAGVIDKTAFVFGQMNEPPGARMRVGLAGLTIAEYFRDEEHQDVLL
CCCCCCCCEEEEEHHCCCEEHHHHEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHH
FIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVP
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPAPATTFAHLDATTVLSRSIAEMGIYPAVDPLDSTSRILEPHIVGEEHYYVARK
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEECCCCHHHHHHH
VQEILQRYKELQDIIAILGMEELTEEDRLIVYRARKIQRFLSQPFFVAEAFTGTPGKYVP
HHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCC
LKETIRGFKKIVEGEMDDIPEPAFYMVGTIDEVYEKAEKMK
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MKKGYITQVIGPVVDIRFEGDLPPINNAIKIPMGDRELVVEVAQHIGDNTVRCVAMASTD
CCCCHHHHHHCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCH
GLRRGMECIDTGGPIMVPVGKGVLGRMFNVLGQPIDELGEVKDVKYMPIHKKPPSFEEQN
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCCCCC
PATEILETGIKVIDLLTPYPKGGKIGLFGGAGVGKTVLIMELIRNVAIEHGGYSIFAGVG
CHHHHHHCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
ERSREGNELWLEMHEAGVIDKTAFVFGQMNEPPGARMRVGLAGLTIAEYFRDEEHQDVLL
CCCCCCCCEEEEEHHCCCEEHHHHEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHH
FIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVP
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPAPATTFAHLDATTVLSRSIAEMGIYPAVDPLDSTSRILEPHIVGEEHYYVARK
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEECCCCHHHHHHH
VQEILQRYKELQDIIAILGMEELTEEDRLIVYRARKIQRFLSQPFFVAEAFTGTPGKYVP
HHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCC
LKETIRGFKKIVEGEMDDIPEPAFYMVGTIDEVYEKAEKMK
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336