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The map label for this gene is LytT [H]

Identifier: 20807062

GI number: 20807062

Start: 566471

End: 567181

Strand: Direct

Name: LytT [H]

Synonym: TTE0561

Alternate gene names: 20807062

Gene position: 566471-567181 (Clockwise)

Preceding gene: 20807061

Following gene: 20807063

Centisome position: 21.06

GC content: 32.63

Gene sequence:

>711_bases
ATGCTCAGAGTTGTTGTCGCGGAGGATGATGAGATTTTCAGGAGGCAGTTAATAGAGTTTCTTAAAAAGATAGATGGGAT
AAGTGTTGAGTACTTTACTGATGATGGTAGAGAGGCTTTAGAAGCTTTAAACAAGATTAAACCGGAAATAGCAATTTTGG
ACATCGAACTTTTCCGCATGTCAGGAATTGAGGTAGCGAAAAAAGTAAGAGAAACCATGCCTTTTTTGGAGATAATTTTT
ATTACTTCTTTTGAAGAGTACATAAAAGAAGCAGTAAAGCTTTACGCTTCTGATTATATTGAAAAGCCATTAAAAGAAGA
GAGATTAAGAGAAACTATTGAAAGGATAAAGAAAAGGTTTTTAAATATTGAAAATTACCTTCCAGTACCTGTGAAGGACA
ATATGAGGCTTATAAATCCCAGAGAGGTTTACTTTGTTCAGGCTAAAAAGAAAAGAAGCGTAATTTACACAGGAGAAGAA
AAAATTGAATGTGATTATTCTTTAAAAGAACTGGAAGAAATATTGCCAGGGGATATATTTTTTAGGACCAATCGCTCTTA
TCTGGTCAATATTTTAAAAGTAGAGGCTTTGAAGGAAAAAAACAGGACTTCTTTTGAAATTACTTTTAAAGGTTGTGCTT
TTAAAGCCTACCTTTCAAAGGATTTATATCAGGAATTTAGGAAAAGGGTGAAAGAGATTTATAGAAATTAA

Upstream 100 bases:

>100_bases
GCTTTTTACCACAGCTGGCAGTTGCAATTTTGTTTTCTATTCTCATCCGCAAATACAGACTTTTTCTCTTTGTTGAGTAA
ATACAGTGGGGATGAAAGGT

Downstream 100 bases:

>100_bases
ATGGCGGGGAATGTAGATGTTTAAGAATATTTATAAAAGCGCGATGCTGATTTATGTAATTCAAATGGTCTTAATAGTGA
TTTTGGTAAATAATAATTTC

Product: response regulators of cell autolysis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MLRVVVAEDDEIFRRQLIEFLKKIDGISVEYFTDDGREALEALNKIKPEIAILDIELFRMSGIEVAKKVRETMPFLEIIF
ITSFEEYIKEAVKLYASDYIEKPLKEERLRETIERIKKRFLNIENYLPVPVKDNMRLINPREVYFVQAKKKRSVIYTGEE
KIECDYSLKELEEILPGDIFFRTNRSYLVNILKVEALKEKNRTSFEITFKGCAFKAYLSKDLYQEFRKRVKEIYRN

Sequences:

>Translated_236_residues
MLRVVVAEDDEIFRRQLIEFLKKIDGISVEYFTDDGREALEALNKIKPEIAILDIELFRMSGIEVAKKVRETMPFLEIIF
ITSFEEYIKEAVKLYASDYIEKPLKEERLRETIERIKKRFLNIENYLPVPVKDNMRLINPREVYFVQAKKKRSVIYTGEE
KIECDYSLKELEEILPGDIFFRTNRSYLVNILKVEALKEKNRTSFEITFKGCAFKAYLSKDLYQEFRKRVKEIYRN
>Mature_236_residues
MLRVVVAEDDEIFRRQLIEFLKKIDGISVEYFTDDGREALEALNKIKPEIAILDIELFRMSGIEVAKKVRETMPFLEIIF
ITSFEEYIKEAVKLYASDYIEKPLKEERLRETIERIKKRFLNIENYLPVPVKDNMRLINPREVYFVQAKKKRSVIYTGEE
KIECDYSLKELEEILPGDIFFRTNRSYLVNILKVEALKEKNRTSFEITFKGCAFKAYLSKDLYQEFRKRVKEIYRN

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=242, Percent_Identity=25.6198347107438, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082052, Length=224, Percent_Identity=27.2321428571429, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28226; Mature: 28226

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVVVAEDDEIFRRQLIEFLKKIDGISVEYFTDDGREALEALNKIKPEIAILDIELFRM
CEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHH
SGIEVAKKVRETMPFLEIIFITSFEEYIKEAVKLYASDYIEKPLKEERLRETIERIKKRF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LNIENYLPVPVKDNMRLINPREVYFVQAKKKRSVIYTGEEKIECDYSLKELEEILPGDIF
CCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEECCCCEECCCCHHHHHHHCCCCEE
FRTNRSYLVNILKVEALKEKNRTSFEITFKGCAFKAYLSKDLYQEFRKRVKEIYRN
EECCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRVVVAEDDEIFRRQLIEFLKKIDGISVEYFTDDGREALEALNKIKPEIAILDIELFRM
CEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHH
SGIEVAKKVRETMPFLEIIFITSFEEYIKEAVKLYASDYIEKPLKEERLRETIERIKKRF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LNIENYLPVPVKDNMRLINPREVYFVQAKKKRSVIYTGEEKIECDYSLKELEEILPGDIF
CCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEECCCCEECCCCHHHHHHHCCCCEE
FRTNRSYLVNILKVEALKEKNRTSFEITFKGCAFKAYLSKDLYQEFRKRVKEIYRN
EECCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]