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The map label for this gene is MhpD [C]

Identifier: 20806781

GI number: 20806781

Start: 264165

End: 264893

Strand: Direct

Name: MhpD [C]

Synonym: TTE0260

Alternate gene names: 20806781

Gene position: 264165-264893 (Clockwise)

Preceding gene: 20806780

Following gene: 20806784

Centisome position: 9.82

GC content: 36.9

Gene sequence:

>729_bases
ATGAGGATTGTGAGAGTGGATAAAGAACCTGACAGTTATGGTATCCTAGAAAACGACAAGGTCATCTTATTGAAGGAAGG
GGAAACTTTTTTATATGGATTAAATGAAGTAAAACTTCTTCCTCCCTGTATTCCTTCTAAGGCTATATGCGTAGGTTTAA
ATTATAAAGACCACATAGAGGAGATGGGGGATAAAATTCCAGAGGAACCTACCTTATTTATAAAACCTTCCACTGCAGTA
ATTGGGCCTGATGATTACATAATTCTTCCTGAAATGTCTCGAAGGGTGGATTATGAAGGAGAATTGGCTGTTGTCATAGG
AAGAAAAGCTAAAAATGTTTCTATAGAGGAAGCAAAAAATTACATACTTGGCTATACTATAGCAAATGATGTGACAGCAA
GAGATCTGCAGGCAAAAGATGGCCAGTGGACAAGAGCCAAGTCTTTTGATACCTTTTTGCCTATAGGGCCTTGGATTGTG
ACAGACCTAGACCCTACTTCTTTAAATATAACTACATATGTAAACGGGGAAGTAAAGCAAAAGAGCAATACAAAGTATTT
GATATTTAATGTATTTAAGCTTGTAAGTTTTATATCTCACATAATGACTCTAAACCCGGGAGATGTCATATTGACTGGCA
CTCCTTCAGGTGTTGGACCCTTAAAGTCAGGAGATGTTGTGACAATTGAAATAGAGGGGATAGGAAAGTTGACAAATAGA
GTAAAATAA

Upstream 100 bases:

>100_bases
AATATATAAAAAACCGAAAATAAGCCTTTTTAGGCTATTTTTTTATTATCTTTTTTATGGTAAAATACTATTCAAATCTA
TTTAAAAGGAGGTTTGTGAT

Downstream 100 bases:

>100_bases
AATCAAATTACAAAAAGGACAATAAAATATATAATCAACCCGATTAAAGATAGAGGAATTCCTACCAAAGCCCATTCGCG
GCTTTTTATGTTAAGCTTTC

Product: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRIVRVDKEPDSYGILENDKVILLKEGETFLYGLNEVKLLPPCIPSKAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAV
IGPDDYIILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKNYILGYTIANDVTARDLQAKDGQWTRAKSFDTFLPIGPWIV
TDLDPTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGPLKSGDVVTIEIEGIGKLTNR
VK

Sequences:

>Translated_242_residues
MRIVRVDKEPDSYGILENDKVILLKEGETFLYGLNEVKLLPPCIPSKAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAV
IGPDDYIILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKNYILGYTIANDVTARDLQAKDGQWTRAKSFDTFLPIGPWIV
TDLDPTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGPLKSGDVVTIEIEGIGKLTNR
VK
>Mature_242_residues
MRIVRVDKEPDSYGILENDKVILLKEGETFLYGLNEVKLLPPCIPSKAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAV
IGPDDYIILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKNYILGYTIANDVTARDLQAKDGQWTRAKSFDTFLPIGPWIV
TDLDPTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGPLKSGDVVTIEIEGIGKLTNR
VK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=220, Percent_Identity=45.9090909090909, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI156231349, Length=220, Percent_Identity=45, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI13654274, Length=200, Percent_Identity=40, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=40.1015228426396, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI66348062, Length=192, Percent_Identity=40.625, Blast_Score=153, Evalue=1e-37,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=42.8571428571429, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17557057, Length=190, Percent_Identity=41.5789473684211, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=32.8888888888889, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28572127, Length=220, Percent_Identity=44.5454545454545, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=39.63133640553, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571789, Length=202, Percent_Identity=39.1089108910891, Blast_Score=140, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 26842; Mature: 26842

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVRVDKEPDSYGILENDKVILLKEGETFLYGLNEVKLLPPCIPSKAICVGLNYKDHIE
CEEEEECCCCCCCCEECCCCEEEEECCCEEEEECCCEEECCCCCCCCEEEEECCCHHHHH
EMGDKIPEEPTLFIKPSTAVIGPDDYIILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKN
HHHHHCCCCCEEEECCCEEEECCCCEEECCCHHCCCCCCCCEEEEEECCCCCCCHHHCCC
YILGYTIANDVTARDLQAKDGQWTRAKSFDTFLPIGPWIVTDLDPTSLNITTYVNGEVKQ
EEEEEEEECCCEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCEEEC
KSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGPLKSGDVVTIEIEGIGKLTNR
CCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHC
VK
CC
>Mature Secondary Structure
MRIVRVDKEPDSYGILENDKVILLKEGETFLYGLNEVKLLPPCIPSKAICVGLNYKDHIE
CEEEEECCCCCCCCEECCCCEEEEECCCEEEEECCCEEECCCCCCCCEEEEECCCHHHHH
EMGDKIPEEPTLFIKPSTAVIGPDDYIILPEMSRRVDYEGELAVVIGRKAKNVSIEEAKN
HHHHHCCCCCEEEECCCEEEECCCCEEECCCHHCCCCCCCCEEEEEECCCCCCCHHHCCC
YILGYTIANDVTARDLQAKDGQWTRAKSFDTFLPIGPWIVTDLDPTSLNITTYVNGEVKQ
EEEEEEEECCCEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCEEEEEEEECCEEEC
KSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGPLKSGDVVTIEIEGIGKLTNR
CCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]