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The map label for this gene is macB [H]

Identifier: 20806779

GI number: 20806779

Start: 262442

End: 263617

Strand: Direct

Name: macB [H]

Synonym: TTE0258

Alternate gene names: 20806779

Gene position: 262442-263617 (Clockwise)

Preceding gene: 20806778

Following gene: 20806780

Centisome position: 9.76

GC content: 37.5

Gene sequence:

>1176_bases
GTGAGATATGTACAGGCATTGAAAATTGCTATAAGGAGTATCCTTAGCAATAAGTTAAGGTCGTTTTTGACAATGTTGGG
AATCATAATAGGTGTTACAGCTGTGATAGCGTTGGTCAGCATAGGGCAGGGTTCTACAAAGAGTGTAACTTCCCAAATTC
AAAGCATGGGGTCAAACCTCATAATGGTGAGTGTTATGGGACGCGGATCTCAAGCGTCTCTCACTTATGAGCAAGCGATG
ACATTAAAGGATGGGAATTATATAAAAGCGGTTTCACCTGTCATTTCTTCAAATGTCACTGCTAAGTACGGCAACAATTC
AGTAGATTCTGCTATGGTAAATGGAGTAAATAGTGATTACCAGGCAATTCGCAGCATACAGGTAGCTGAAGGAAGATTTA
TTTCGCCAATGGATGATGAGGGAAGAAATAAAGTTGCGGTTTTAGGGCACAATGTTGCGACAGAATTGTTTGGGTTTACA
GATCCGGTTGGGAAAACTATAAAATTAAACGGTCAGGCTTTTACAGTAGTTGGAGTTTTAGCATTAAAAGGATCTTCAAT
TGCAGGTTCAGACGATGACGCAATATTTATTCCAATAAAGACGATGTTTTATTTCGCAAAAAATAAAAATATAAGGCAAA
TATATATTGGGGCGTCAAATCCTGATACTGTAGAAATAGCCAAAAATATGATAAATAATCACCTGTTGGAGGTTTTTAAA
GGCGATACCAGTGCTTTTACAATAATTGACCAGTCACAGATTTTATCAACGGTAAATAGTGTTACTACTACGCTGAGTTT
GCTTCTTGGAGGAATTGCTGGGATTTCACTTTTAGTCGGTGGAATTGGAATAATGAATATAATGCTTGTATCGGTTACAG
AAAGAACGAGAGAGATAGGAATAAGAAAAGCACTAGGGGCAAAAAAGAGAGATATTCTTCTACAGTTCATTATTGAATCT
TTAACTTTAAGTGGGTTGGGTGGAATATTGGGAATTATAGCAGGATATATTTTAGCAGTGACTTTAGGGAAGGCTATGAA
TATAGATGCGAACCCTACTTTGAGCACGATTTTGATATCTTTTTCTTTTTCAGTTTTGGTGGGACTTTTCTTTGGCGTGT
ATCCTGCGAATAAGGCTGCTAATCTCAATCCAATTGAGGCTTTACGGTATGAATAA

Upstream 100 bases:

>100_bases
CAGTGGTGGTTGTCACTCACGACCCAAATATAGCAGCTCAGGCAAAGAGGATAGTGAGAATAAAAGATGGGCGCATTCTA
GGGGATGAGGTGAAGGCGCA

Downstream 100 bases:

>100_bases
TTTTTATTGATTTTTTGTCGAAAAAGATTTAAAATTGAATCGACAGTTTTTATAGGGGAGGAAATTAGATGATAAAGTGG
ACCGAGTCCCTGTCAGTAGG

Product: ABC-type transport systems, involved in lipoprotein release, permease components

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRYVQALKIAIRSILSNKLRSFLTMLGIIIGVTAVIALVSIGQGSTKSVTSQIQSMGSNLIMVSVMGRGSQASLTYEQAM
TLKDGNYIKAVSPVISSNVTAKYGNNSVDSAMVNGVNSDYQAIRSIQVAEGRFISPMDDEGRNKVAVLGHNVATELFGFT
DPVGKTIKLNGQAFTVVGVLALKGSSIAGSDDDAIFIPIKTMFYFAKNKNIRQIYIGASNPDTVEIAKNMINNHLLEVFK
GDTSAFTIIDQSQILSTVNSVTTTLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKRDILLQFIIES
LTLSGLGGILGIIAGYILAVTLGKAMNIDANPTLSTILISFSFSVLVGLFFGVYPANKAANLNPIEALRYE

Sequences:

>Translated_391_residues
MRYVQALKIAIRSILSNKLRSFLTMLGIIIGVTAVIALVSIGQGSTKSVTSQIQSMGSNLIMVSVMGRGSQASLTYEQAM
TLKDGNYIKAVSPVISSNVTAKYGNNSVDSAMVNGVNSDYQAIRSIQVAEGRFISPMDDEGRNKVAVLGHNVATELFGFT
DPVGKTIKLNGQAFTVVGVLALKGSSIAGSDDDAIFIPIKTMFYFAKNKNIRQIYIGASNPDTVEIAKNMINNHLLEVFK
GDTSAFTIIDQSQILSTVNSVTTTLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKRDILLQFIIES
LTLSGLGGILGIIAGYILAVTLGKAMNIDANPTLSTILISFSFSVLVGLFFGVYPANKAANLNPIEALRYE
>Mature_391_residues
MRYVQALKIAIRSILSNKLRSFLTMLGIIIGVTAVIALVSIGQGSTKSVTSQIQSMGSNLIMVSVMGRGSQASLTYEQAM
TLKDGNYIKAVSPVISSNVTAKYGNNSVDSAMVNGVNSDYQAIRSIQVAEGRFISPMDDEGRNKVAVLGHNVATELFGFT
DPVGKTIKLNGQAFTVVGVLALKGSSIAGSDDDAIFIPIKTMFYFAKNKNIRQIYIGASNPDTVEIAKNMINNHLLEVFK
GDTSAFTIIDQSQILSTVNSVTTTLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKRDILLQFIIES
LTLSGLGGILGIIAGYILAVTLGKAMNIDANPTLSTILISFSFSVLVGLFFGVYPANKAANLNPIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=404, Percent_Identity=35.1485148514851, Blast_Score=197, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41570; Mature: 41570

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVQALKIAIRSILSNKLRSFLTMLGIIIGVTAVIALVSIGQGSTKSVTSQIQSMGSNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IMVSVMGRGSQASLTYEQAMTLKDGNYIKAVSPVISSNVTAKYGNNSVDSAMVNGVNSDY
EEEEEECCCCCCEEEHHHHEEECCCCEEEEHHHHHHCCCEEECCCCCHHHHHHCCCCHHH
QAIRSIQVAEGRFISPMDDEGRNKVAVLGHNVATELFGFTDPVGKTIKLNGQAFTVVGVL
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
ALKGSSIAGSDDDAIFIPIKTMFYFAKNKNIRQIYIGASNPDTVEIAKNMINNHLLEVFK
EECCCCCCCCCCCEEEEEHHHHEEHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
GDTSAFTIIDQSQILSTVNSVTTTLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIG
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKALGAKKRDILLQFIIESLTLSGLGGILGIIAGYILAVTLGKAMNIDANPTLSTILIS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
FSFSVLVGLFFGVYPANKAANLNPIEALRYE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MRYVQALKIAIRSILSNKLRSFLTMLGIIIGVTAVIALVSIGQGSTKSVTSQIQSMGSNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IMVSVMGRGSQASLTYEQAMTLKDGNYIKAVSPVISSNVTAKYGNNSVDSAMVNGVNSDY
EEEEEECCCCCCEEEHHHHEEECCCCEEEEHHHHHHCCCEEECCCCCHHHHHHCCCCHHH
QAIRSIQVAEGRFISPMDDEGRNKVAVLGHNVATELFGFTDPVGKTIKLNGQAFTVVGVL
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
ALKGSSIAGSDDDAIFIPIKTMFYFAKNKNIRQIYIGASNPDTVEIAKNMINNHLLEVFK
EECCCCCCCCCCCEEEEEHHHHEEHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
GDTSAFTIIDQSQILSTVNSVTTTLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIG
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKALGAKKRDILLQFIIESLTLSGLGGILGIIAGYILAVTLGKAMNIDANPTLSTILIS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
FSFSVLVGLFFGVYPANKAANLNPIEALRYE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA